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2025-12-5 20:26:35
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Nishiura H, Kumagai A, Mine J, Takadate Y, Sakuma. Phylogenetic and Pathogenic Analysis of H5N1 and H5N6 High Pathogenicity Avian Influenza Virus Isolated from Poultry Farms (Layer and Broiler Chickens) in Japan in the 2023/2024 Season. Viruses 16, no. 12: 1956.  Abstract  
submitted by kickingbird at Dec, 21, 2024 from Viruses 16, no. 12: 1956 (via https://www.mdpi.com/1999-4915/16/12/1956)
During the 2023–2024 winter, 11 high pathogenicity avian influenza (HPAI) outbreaks caused by clade 2.3.4.4b H5N1 and H5N6 HPAI viruses were confirmed in Japanese domestic poultry among 10 prefectures ...

Komami M, Komu JG, Ishiguro Y, Sasaki M, Matsuda S. Detection of antibodies against H5 subtype highly pathogenic avian influenza viruses in multiple raccoons in Tokachi District, Hokkaido, Japan, from 2022 to 2023. Virus Res. 2024 Dec 15:199515.  Abstract  
submitted by kickingbird at Dec, 18, 2024 from Virus Res. 2024 Dec 15:199515 (via https://pubmed.ncbi.nlm.nih.gov/39689812/)
In recent years, infection cases of H5 subtype highly pathogenic avian influenza viruses (HPAIVs) in wild mammals have increased globally. To obtain recent epidemiological information regarding influenza ...

Li M, Wu Y, Li H, Song W, Chen Z, Peng Y, Yang B,. Mutagenesis studies suggest a mechanism for influenza polymerase stalling during polyadenylation. Nucleic Acids Res. 2024 Dec 16:gkae1225.  Abstract  
submitted by kickingbird at Dec, 17, 2024 from Nucleic Acids Res. 2024 Dec 16:gkae1225 (via https://academic.oup.com/nar/advance-article/doi/10.1093/nar)
Influenza polymerase (FluPol) carries out both viral transcription and replication using the same viral genome segment as a template to yield distinct end products. However, it remains largely unclear ...

Wang X, Yu H, Ma Y, Zhang P, Wang X, Liang J, Zhan. The novel H10N3 avian influenza virus acquired airborne transmission among chickens: an increasing threat to public health. mBio. 2024 Dec 16:e0236324.  Abstract  
submitted by kickingbird at Dec, 17, 2024 from mBio. 2024 Dec 16:e0236324 (via https://journals.asm.org/doi/10.1128/mbio.02363-24)
Following two human infections with the H10N3 avian influenza virus (AIV) in 2021 and 2022, a third case was discovered in Yunnan, China, in 2024, raising concerns about the potential for future pandemics. ...

Andrew J. Lail, etc.,al. [preprint]Pasteurized retail dairy enables genomic surveillance of H5N1 avian influenza virus in United States cattle. https://doi.org/10.1101/2024.12.12.24318872.  Abstract  
submitted by kickingbird at Dec, 16, 2024 from https://doi.org/10.1101/2024.12.12.24318872 (via https://www.medrxiv.org/content/10.1101/2024.12.12.24318872v)
Highly pathogenic avian influenza (HPAI) viruses with H5 hemagglutinin (HA) genes (clade 2.3.4.4b) are causing an ongoing panzootic in wild birds. Circulation of these viruses is associated with spillover ...

Jack Ward, etc.,al. [preprint]Estimates of epidemiological parameters for H5N1 influenza in humans: a rapid review. https://doi.org/10.1101/2024.12.11.24318702.  Abstract  
submitted by kickingbird at Dec, 16, 2024 from https://doi.org/10.1101/2024.12.11.24318702 (via https://www.medrxiv.org/content/10.1101/2024.12.11.24318702v)
Background The ongoing H5N1 panzootic in mammals has amplified zoonotic pathways to facilitate human infection. Characterising key epidemiological parameters for H5N1 is critical should this become widespread.Aim ...

Pia Ryt-Hansen, etc.,al. [preprint]Rapid Surge of Reassortant A(H1N1) Influenza Viruses in Danish Swine and their Zoonotic Potential. https://doi.org/10.1101/2024.12.11.627926.  Abstract  
submitted by kickingbird at Dec, 16, 2024 from https://doi.org/10.1101/2024.12.11.627926 (via https://www.biorxiv.org/content/10.1101/2024.12.11.627926v1)
In 2018, a single detection of a novel reassortant swine influenza A virus (swIAV) was made in Denmark. The hemagglutinin (HA) of the virus was from the H1N1 pandemic 2009 (H1N1pdm09) lineage and the neuraminidase ...

Ayrton S Gouveia, Leonardo G Mata, Daniel A.M. Vil. [preprint]High cumulative viral titers of influenza virus in animals with significant disease fatality rates indicate a potential trade-off between fatality and transmissibility. https://doi.org/10.1101/2024.12.11.627227.  Abstract  
submitted by kickingbird at Dec, 16, 2024 from https://doi.org/10.1101/2024.12.11.627227 (via https://www.biorxiv.org/content/10.1101/2024.12.11.627227v1)
Evaluating the trade-off hypothesis for the evolution of virulence using empirical data poses significant challenges. The hypothesis suggests that pathogens evolve to maximize transmissibility, but fatality ...

Alessandro Zulli, etc.,al. Infectivity and Persistence of Influenza A Virus in Raw Milk. Environ. Sci. Technol. Lett. 2024.  Abstract  
submitted by kickingbird at Dec, 15, 2024 from Environ. Sci. Technol. Lett. 2024 (via https://pubs.acs.org/doi/10.1021/acs.estlett.4c00971)
Influenza A viruses present important public health risks, with recent outbreaks of highly pathogenic avian influenza (HPAI) H5N1 in dairy cattle raising concerns about potential transmission through raw ...

Goraichuk IV, Risalvato J, Pantin-Jackwood M, Suar. Improved influenza A whole-genome sequencing protocol. Front Cell Infect Microbiol. 2024 Nov 28;14:149727.  Abstract  
submitted by kickingbird at Dec, 15, 2024 from Front Cell Infect Microbiol. 2024 Nov 28;14:149727 (via https://www.frontiersin.org/journals/cellular-and-infection-)
Influenza A virus poses significant public health challenges due to its high mutation rate and zoonotic potential. Whole-genome sequencing (WGS) is crucial for monitoring and characterizing these viruses. ...

Ssematimba A, Malladi S, Bonney PJ, St Charles KM,. Estimating the time of Highly Pathogenic Avian Influenza virus introduction into United States poultry flocks during the 2022/24 epizootic. PLoS One. 2024 Dec 13;19(12):e0310733.  Abstract  
submitted by kickingbird at Dec, 15, 2024 from PLoS One. 2024 Dec 13;19(12):e0310733 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Following confirmation of the first case of the ongoing U.S. HPAI H5N1 epizootic in commercial poultry on February 8, 2022, the virus has continued to devastate the U.S. poultry sector and the pathogen ...

Mainenti M, Siepker C, Magstadt DR, Gauger P, Baum. Distribution of lesions and detection of influenza A(H5N1) virus, clade 2.3.4.4b, in ante- and postmortem samples from naturally infected domestic cats on U.S. dairy farms. J Vet Diagn Invest. 2024 Dec 14:10406387241300464.  Abstract  
submitted by kickingbird at Dec, 15, 2024 from J Vet Diagn Invest. 2024 Dec 14:10406387241300464 (via https://journals.sagepub.com/doi/10.1177/10406387241300464)
In March 2024, highly pathogenic avian influenza A(H5N1) virus, clade 2.3.4.4b, was detected in dairy cows in the United States, and at the same time in resident cats on affected farms. To help guide sample ...

Williams SL, Qi L, Sheng ZM, Xiao Y, Freeman A, Ma. Effect of pandemic influenza A virus PB1 genes of avian origin on viral RNA polymerase activity and pathogenicity. Sci Adv. 2024 Dec 13;10(50):eads5735.  Abstract  
submitted by kickingbird at Dec, 15, 2024 from Sci Adv. 2024 Dec 13;10(50):eads5735 (via https://www.science.org/doi/10.1126/sciadv.ads5735)
Zoonotic influenza A virus (IAV) infections pose a substantial threat to global health. The influenza RNA-dependent RNA polymerase (RdRp) comprises the PB2, PB1, and PA proteins. Of the last four pandemic ...

Sreenivasan CC, Thomas M, Kaushik RS, Wang D, Li F. Influenza A in Bovine Species: A Narrative Literature Review. Viruses. 2019 Jun 17;11(6):561.  Abstract  
submitted by kickingbird at Dec, 14, 2024 from Viruses. 2019 Jun 17;11(6):561 (via https://www.mdpi.com/1999-4915/11/6/561)
It is quite intriguing that bovines were largely unaffected by influenza A, even though most of the domesticated and wild animals/birds at the human-animal interface succumbed to infection over the past ...

Kieran TJ, Sun X, Maines TR, Belser JA. Optimal thresholds and key parameters for predicting influenza A virus transmission events in ferrets. Npj Viruses. 2024;2(1):64.  Abstract  
submitted by kickingbird at Dec, 13, 2024 from Npj Viruses. 2024;2(1):64 (via https://www.nature.com/articles/s44298-024-00074-w)
Although assessments of influenza A virus transmissibility in the ferret model play a critical role in pandemic risk evaluations, few studies have investigated which virological data collected from virus-inoculated ...

Borkenhagen LK, Runstadler JA. Examining the Influenza A Virus Sialic Acid Binding Preference Predictions of a Sequence-Based Convolutional Neural Network. Influenza Other Respir Viruses. 2024 Dec;18(12):e7.  Abstract  
submitted by kickingbird at Dec, 13, 2024 from Influenza Other Respir Viruses. 2024 Dec;18(12):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70044)
Background: Though receptor binding specificity is well established as a contributor to host tropism and spillover potential of influenza A viruses, determining receptor binding preference of a specific ...

Joao Paulo Portela Catani, etc.,al. [preprint]The antigenic landscape of N1 neuraminidase in human influenza A virus strains isolated between 2009 and 2020. https://doi.org/10.1101/2024.12.10.627724.  Abstract  
submitted by kickingbird at Dec, 12, 2024 from https://doi.org/10.1101/2024.12.10.627724 (via https://www.biorxiv.org/content/10.1101/2024.12.10.627724v1)
The clinical burden caused by influenza can be mitigated by the prophylactic use of seasonal influenza vaccines. Their immunogen composition is revised biannually to optimally match the antigenic drift ...

Elyse Stachler, etc.,al. [preprint]Establishing methods to monitor H5N1 influenza virus in dairy cattle milk. https://doi.org/10.1101/2024.12.04.24318491.  Abstract  
submitted by kickingbird at Dec, 11, 2024 from https://doi.org/10.1101/2024.12.04.24318491 (via https://www.medrxiv.org/content/10.1101/2024.12.04.24318491v)
Highly Pathogenic Avian Influenza strain H5N1 has caused a multi-state outbreak among US dairy cattle, spreading across 15 states and infecting hundreds of herds since its onset. We rapidly developed and ...

Hubbard LE, Stelzer EA, Poulson RL, Kolpin DW, Sza. Development of a Large-Volume Concentration Method to Recover Infectious Avian Influenza Virus from the Aquatic Environment. Viruses. 2024; 16(12):1898.  Abstract  
submitted by kickingbird at Dec, 11, 2024 from Viruses. 2024; 16(12):1898 (via https://www.mdpi.com/1999-4915/16/12/1898)
Since late 2021, outbreaks of highly pathogenic avian influenza virus have caused a record number of mortalities in wild birds, domestic poultry, and mammals in North America. Wetlands are plausible environmental ...

Ramos-Martínez I, Ramos-Martínez E, Saavedra-Monta. Meta-Analysis of Seroprevalence and Prevalence of Influenza A Viruses (Subtypes H3N2, H3N8, and H1N1) in Dogs. Animals. 2024; 14(23):3467.  Abstract  
submitted by kickingbird at Dec, 11, 2024 from Animals. 2024; 14(23):3467 (via https://www.mdpi.com/2076-2615/14/23/3467)
Influenza A is a zoonotic disease that affects dogs. In this work, we performed a meta-analysis of the prevalence and seroprevalence of reports from all over the world. We found a combined seroprevalence ...

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