Laura Reusch, etc.,al. [preprint]Antibodies, Memory B Cells, and Antigen Valency Reshape B Cell Responses to Drifted Influenza Virus Vaccination. https://doi.org/10.1101/2025.11.07.687210. Abstract
submitted by kickingbird at Nov, 9, 2025 from https://doi.org/10.1101/2025.11.07.687210 (via https://www.biorxiv.org/content/10.1101/2025.11.07.687210v1)
Antigenic drift in influenza A virus hemagglutinin (HA) limits humoral protective immunity. Here, we combine cell fate mapping with adoptive transfer of antigenic-site-specific antibodies (Abs) and memory ... Deming, M.E., Toapanta, F.R., Pasetti, M. et al. An intranasal adjuvanted, recombinant influenza A/H5 vaccine primes against diverse H5N1 clades: a phase I trial. Nat Commun 16, 9321 (2025). Abstract
submitted by kickingbird at Nov, 7, 2025 from Nat Commun 16, 9321 (2025) (via https://www.nature.com/articles/s41467-025-64686-3)
Mucosal influenza vaccines may provide improved protection against infection and transmission, but their development is hindered by absence of immune correlates of protection. Here, we report a randomized, ... Tran H, Berke O, Ricker N, Poljak Z. Evaluating machine learning approaches for host prediction using H3 influenza genomic data. PLoS One. 2025 Nov 5;20(11):e0336142. Abstract
submitted by kickingbird at Nov, 6, 2025 from PLoS One. 2025 Nov 5;20(11):e0336142 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Background: H3 influenza A viruses (IAV) have been shown to frequently cross the species barrier which can be an important factor in sustained transmission and spread. Machine learning methods have been ... Nahara Vargas-Maldonado, etc.,al. [preprint]Controlled human influenza infection reveals heterogeneous expulsion of infectious virus into air. https://doi.org/10.1101/2025.11.03.25339190. Abstract
submitted by kickingbird at Nov, 6, 2025 from https://doi.org/10.1101/2025.11.03.25339190 (via https://www.medrxiv.org/content/10.1101/2025.11.03.25339190v)
Influenza virus is transmitted via respiratory expulsions, but detection of infectious virus in such expulsions has been challenging. Here, we describe quantification and genotyping of infectious virus ... Hunter Joseph Ries, etc.,al. [preprint]Weak selection and stochastic processes limit the emergence of antigenic variants during household transmission of influenza A viruses. https://doi.org/10.1101/2025.11.04.686470. Abstract
submitted by kickingbird at Nov, 6, 2025 from https://doi.org/10.1101/2025.11.04.686470 (via https://www.biorxiv.org/content/10.1101/2025.11.04.686470v1)
Influenza viruses undergo antigenic drift, the gradual accumulation of mutations that cause antigenic changes in the viral surface proteins hemagglutinin (HA) and neuraminidase (NA). Although selection ... Farazi R, Tusar MTT, Roy CR, Mia R, Mozumder A, Da. Complete genome sequence of a highly pathogenic H5N1 avian influenza virus from recent poultry outbreak in Bangladesh. Microbiol Resour Announc 0:e00825-25. Abstract
submitted by kickingbird at Nov, 6, 2025 from Microbiol Resour Announc 0:e00825-25 (via https://journals.asm.org/doi/10.1128/mra.00825-25)
Highly pathogenic avian influenza virus (H5N1) continues to cause substantial losses in the poultry industry of Bangladesh, with ongoing genetic evolution. This report presents the complete genome sequence ... Kang, H., Yang, Y., Liu, Y. et al. Coupling of polymerase-nucleoprotein-RNA in an influenza virus mini ribonucleoprotein complex. Nat Commun 16, 9741 (2025). Abstract
submitted by kickingbird at Nov, 5, 2025 from Nat Commun 16, 9741 (2025) (via https://www.nature.com/articles/s41467-025-64741-z)
Influenza virus ribonucleoprotein complexes (RNPs), composed of the polymerase complex (FluPol), nucleoprotein (NP), and RNA, are essential for replication and transcription. We report atomic-resolution ... Song Y, Zhang X, Ji J, Li L, Zhou Y, Li P, Ren G,. Genetic characteristics of influenza A/H3N2 virus in Jiaxing, China (2019~2024). Virol J. 2025 Nov 4;22(1):359. Abstract
submitted by kickingbird at Nov, 5, 2025 from Virol J. 2025 Nov 4;22(1):359 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
The rapid evolution of influenza A/H3N2 virus underscores the imperative for ongoing surveillance. In this study, we analyzed 7,872 respiratory samples collected from patients with influenza-like symptoms ... Harrell T.L., etc.,al. Inactivation of avian influenza virus in yogurt made from raw milk. Food Microbiology. Abstract
submitted by kickingbird at Nov, 5, 2025 from Food Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S07400)
In March 2024, highly pathogenic avian influenza (HPAIV) H5N1 was first detected in U.S. dairy cattle and has since spread to herds across at least 17 states. Infected cows typically present with mastitis, ... Christina Leyson, etc.,al. [prepeint]Viral lineage and mode of exposure modulate within host spatial dynamics of influenza A viruses. https://doi.org/10.1101/2025.11.03.686270. Abstract
submitted by kickingbird at Nov, 5, 2025 from https://doi.org/10.1101/2025.11.03.686270 (via https://www.biorxiv.org/content/10.1101/2025.11.03.686270v1)
The upper and lower respiratory tracts (URT and LRT) present distinct environments for influenza A virus (IAV) replication. Their differential features have major implications for viral evolutionary dynamics, ... Biswas, A., Loeffler, K., Kim, D. et al. Inverted H1 hemagglutinin nanoparticle vaccines protect mice against challenges with human H1N1 and bovine H5N1 influenza viruses. npj Vaccines 10, 225 (2025). Abstract
submitted by kickingbird at Nov, 5, 2025 from npj Vaccines 10, 225 (2025) (via https://link.springer.com/article/10.1038/s41541-025-01276-w)
Influenza is a global health concern, causing over 300,000 deaths worldwide annually. Current vaccines and natural infection mainly elicit antibodies against the variable head domain of the hemagglutinin ... Shintaro Shichinohe, etc.,al. [preprint]A cattle-derived human H5N1 isolate suppresses innate immunity despite efficient replication in human respiratory organoids. https://doi.org/10.1101/2025.11.02.684669. Abstract
submitted by kickingbird at Nov, 3, 2025 from https://doi.org/10.1101/2025.11.02.684669 (via https://www.biorxiv.org/content/10.1101/2025.11.02.684669v1)
The H5N1 high pathogenicity avian influenza virus (HPAIV) of clade 2.3.4.4b, which spreads globally via wild birds, has become a major public health concern because it can infect a variety of mammals, ... Wong SS, Zanin M, Song MS, Contreras C, Fabrizio T. Route of Inoculation Determines Symptom Profile and Replication Dynamics After low Pathogenic Avian Influenza A(H7N9) Virus Infection in Ferrets. Influenza Other Respir Viruses. 2025 Nov;19(11):e7. Abstract
submitted by kickingbird at Nov, 3, 2025 from Influenza Other Respir Viruses. 2025 Nov;19(11):e7 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70183)
Background: Although influenza A viruses (IAVs) are respiratory pathogens, infections may occur via nonrespiratory routes. However, the effects of different routes of exposure on the course of infection ... Lin J, Hu P, Mei G, Guo B, Wang S, Yan S, Chen JL,. Role of long non-coding RNA Lnc9101 and Lnc8475 in regulation of innate immune response to influenza virus infection. Poult Sci. 2025 Oct 4;104(12):105944. Abstract
submitted by kickingbird at Nov, 3, 2025 from Poult Sci. 2025 Oct 4;104(12):105944 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Long non-coding RNAs (lncRNAs) are critical regulators of various biological processes, yet their roles in chicken host-virus interactions remain largely unknown. This study investigated the impact of ... Stelfox AJ, Bessonne M, Bourhis JM, Erba EB, Alban. Monomeric structure of influenza A virus NEP/NS2 obtained with an artificial protein highlights conformational plasticity. J Mol Biol. 2025 Oct 30:169511. Abstract
submitted by kickingbird at Nov, 3, 2025 from J Mol Biol. 2025 Oct 30:169511 (via https://www.sciencedirect.com/science/article/abs/pii/S00222)
The influenza virus nuclear export protein (NEP)/non-structural protein 2 (NS2) is a multifunctional protein, involved in viral ribonucleoprotein export from the nucleus, genome replication enhancement, ... Obdulio Garcia-Nicolas, etc.,al. [preprint]An RNA replicon vaccine encoding HA and NA prevents shedding of antigen-drifted 2009 pandemic H1N1 influenza virus in the pig model. https://doi.org/10.1101/2025.11.01.685547. Abstract
submitted by kickingbird at Nov, 3, 2025 from https://doi.org/10.1101/2025.11.01.685547 (via https://www.biorxiv.org/content/10.1101/2025.11.01.685547v1)
Seasonal influenza viruses escape the human immune response by antigenic drift, i.e. the positive selection of point mutations that prevent the binding of inhibitory antibodies to the influenza antigens ... Jiachen Zhao, Lipeng Liu, Lili Li, Dan Wu, Chunna. Preplanned Studies: Phylogenetic and Molecular Characteristics of An H3N8 Avian Influenza Virus Detected in Wild Birds - Beijing, China, September 2024. China CDC Weekly, 2025, 7(44): 1389-1395. Abstract
submitted by kickingbird at Nov, 2, 2025 from China CDC Weekly, 2025, 7(44): 1389-1395 (via https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2025)
Introduction: The H3N8 avian influenza virus (AIV) is recognized for its capacity for interspecies transmission and has been detected in multiple mammalian hosts. Between 2022 and 2023, three human infections ... Xinyue Zhang, Xinyi Sang, Beibei Liu, Quanyu Wang,. Methods and Applications: Developing Machine Learning Prediction Model for Daily Influenza Reported Cases Using Multichannel Surveillance Data - A City, Hubei Province, China, 2023~2025. China CDC Weekly, 2025, 7(44): 1396-1402. Abstract
submitted by kickingbird at Nov, 2, 2025 from China CDC Weekly, 2025, 7(44): 1396-1402 (via https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2025)
IntroductionPublic health surveillance is crucial for decision-making. Given the significant threat of influenza to public health, developing predictive models using multichannel surveillance systems is ... Abdulgader SA, Abdulwahed AM, Almuqrin AM, Aziz IM. Genetic Divergence of H1N1pdm09 in Saudi Arabia: Unveiling a Novel N-Glycosylation Site and Its Role in Vaccine Mismatch. Vaccines. 2025; 13(11):1111. Abstract
submitted by kickingbird at Nov, 2, 2025 from Vaccines. 2025; 13(11):1111 (via https://www.mdpi.com/2076-393X/13/11/1111)
Background/Objectives: Influenza A virus undergoes continuous antigenic drift, necessitating annual vaccine reformulation. Saudi Arabia faces unique epidemiological challenges owing to mass gatherings ... Wilson A, Jauregui R, Gias E, Low YS, Little A, Jo. Phylogenetic and Molecular Characterization of a Novel Reassortant High-Pathogenicity Avian Influenza A (H7N6) Virus Detected in New Zealand Poultry. International Journal of Molecular Sciences. 2025;. Abstract
submitted by kickingbird at Nov, 2, 2025 from International Journal of Molecular Sciences. 2025; (via https://www.mdpi.com/1422-0067/26/21/10623)
H7 high-pathogenicity avian influenza (HPAI) virus outbreaks can cause high rates of morbidity and mortality in poultry flocks, leading to devastating impacts on poultry industries. In December 2024, an ... 7181 items, 20/Page, Page[41/360][|<<] [|<] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [>|] [>>|] |
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