Guangxu Zhang, Yuren Shi, Haoyu Ge, Yuanzhou Wang,. Genomic signatures and host adaptation of H5N1 clade 2.3.4.4b: A call for global surveillance and multi-target antiviral strategies. Current Research in Microbial Sciences. Abstract
submitted by kickingbird at Mar, 31, 2025 from Current Research in Microbial Sciences (via https://www.sciencedirect.com/science/article/pii/S266651742)
The recent report of the first fatality associated with infection by influenza virus H5N1 clade 2.3.4.4b, identified as genotype D1.1, which is distinct from the B3.13 genotype, has sparked fears of a ... Frutos AM, Tenforde MW, Sundaresan D, Naleway AL,. Influenza-associated hospitalization rates by underlying conditions, 2016-17 to 2019-20: A retrospective cohort study. J Infect Dis. 2025 Mar 28:jiaf164. Abstract
submitted by kickingbird at Mar, 30, 2025 from J Infect Dis. 2025 Mar 28:jiaf164 (via https://pubmed.ncbi.nlm.nih.gov/40155312/)
Background: Various underlying medical conditions (UMCs) elevate the risk of influenza-associated hospitalization. We evaluated how these rates changed by type and number of UMCs.Methods: Retrospective ... Ishiguro N, Morioka I, Nakano T, Manabe A, Kawaguc. Clinical and Virologic Outcomes of Baloxavir Compared with Oseltamivir in Pediatric Patients with Influenza in Japan. Infect Dis Ther. 2025 Mar 28. Abstract
submitted by kickingbird at Mar, 30, 2025 from Infect Dis Ther. 2025 Mar 28 (via https://pubmed.ncbi.nlm.nih.gov/40155497/)
Introduction: Baloxavir marboxil, a cap-dependent endonuclease inhibitor, has proven efficacy against influenza. There are limited comparative data between baloxavir and oseltamivir in Japanese pediatric ... Aaron M Frutos, Mark W Tenforde, Devi Sundaresan,. Influenza-associated hospitalization rates by underlying conditions, 2016~17 to 2019~20: A retrospective cohort study. The Journal of Infectious Diseases, 2025;, jiaf164. Abstract
submitted by kickingbird at Mar, 29, 2025 from The Journal of Infectious Diseases, 2025;, jiaf164 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
BackgroundVarious underlying medical conditions (UMCs) elevate the risk of influenza-associated hospitalization. We evaluated how these rates changed by type and number of UMCs.MethodsRetrospective cohorts ... Yu L, Jiang Y, Rang H, Wang X, Cai Y, Yan H, Wu S,. Restriction of influenza A virus replication by host DCAF7-CRL4B axis. J Virol. 2025 Mar 27:e0013325. Abstract
submitted by kickingbird at Mar, 28, 2025 from J Virol. 2025 Mar 27:e0013325 (via https://journals.asm.org/doi/10.1128/jvi.00133-25)
The balance between cellular defense and viral escape determines the fate of influenza A virus (IAV) infection. Viral polymerase activity is critical for the replication and propagation of IAV. The antiviral ... Cordero-Ortiz M, Magtoto R, Cauwels B, Baum DH, Ar. Fluorescent Microsphere Immunoassay for Isotype-Specific H5N1 Antibody Detection in Serum and Milk Samples From Dairy Cattle: A Tool for Epidemiological Surveillance. J Med Virol. 2025 Apr;97(4):e70321. Abstract
submitted by kickingbird at Mar, 28, 2025 from J Med Virol. 2025 Apr;97(4):e70321 (via https://pubmed.ncbi.nlm.nih.gov/40145266/)
The detection of highly pathogenic avian influenza A virus H5N1 in dairy cows in the United States underscores the urgent need for reliable laboratory tools to support epidemiological surveillance. This ... Bessière Pierre, Brun Jessie, Hayes Brandon, March. Cats as sentinels of mammal exposure to H5Nx avian influenza viruses: a seroprevalence study, France, December 2023 to January 2025. Euro Surveill. 2025;30(12):pii=2500189. Abstract
submitted by kickingbird at Mar, 28, 2025 from Euro Surveill. 2025;30(12):pii=2500189 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Highly pathogenicity avian influenza viruses (HPAIV) H5Nx of clade 2.3.4.4b have circulated extensively in recent years and become enzootic in many regions since 2020. This increased circulation has led ... Wang, Yan-He et al. Early-warning signals and the role of H9N2 in the spillover of avian influenza viruses. Med, Mar 25, 2025. Abstract
submitted by kickingbird at Mar, 28, 2025 from Med, Mar 25, 2025 (via https://www.cell.com/med/fulltext/S2666-6340(25)00066-2)
BackgroundThe spillover of avian influenza viruses (AIVs) presents a significant global public health threat, leading to unpredictable and recurring pandemics. Current pandemic assessment tools suffer ... Stachler E, Gnirke A, McMahon K, et al. Establishing Methods to Monitor Influenza (A)H5N1 Virus in Dairy Cattle Milk, Massachusetts, USA. Emerging Infectious Diseases. 2025;31(13). Abstract
submitted by kickingbird at Mar, 27, 2025 from Emerging Infectious Diseases. 2025;31(13) (via https://wwwnc.cdc.gov/eid/article/31/13/25-0087_article)
Highly pathogenic avian influenza A(H5N1) virus has caused a multistate outbreak among US dairy cattle, spreading across 16 states and infecting hundreds of herds since its onset. We rapidly developed ... Ramey AM, Beckmen KB, Saalfeld DT, Nicholson KL, M. Exposure of Wild Mammals to Influenza A(H5N1) Virus, Alaska, USA, 2020-2023. Emerg Infect Dis. 2025 Apr;31(4):804-808. Abstract
submitted by kickingbird at Mar, 27, 2025 from Emerg Infect Dis. 2025 Apr;31(4):804-808 (via https://wwwnc.cdc.gov/eid/article/31/4/24-1002_article)
Serum samples from wild mammals inhabiting Alaska, USA, showed that 4 species, including Ursus arctos bears and Vulpes vulpes foxes, were exposed to influenza A(H5N1) viruses. Results indicated some mammals ... Lang Y, Shi L, Roy S, Gupta D, Dai C, Khalid MA, Z. Detection of antibodies against influenza A viruses in cattle. J Virol 0:e02138-24. Abstract
submitted by kickingbird at Mar, 27, 2025 from J Virol 0:e02138-24 (via https://journals.asm.org/doi/10.1128/jvi.02138-24)
Unexpected outbreaks caused by the H5N1 highly pathogenic avian influenza virus (HPAIV) in dairy cows in the United States (US) have raised significant veterinary and public health concerns. When and how ... Otto, S.P., Edgerton, S.V. Lengthy delays in H5N1 genome submissions to GISAID. Nat Biotechnol (2025). Abstract
submitted by kickingbird at Mar, 26, 2025 from Nat Biotechnol (2025) (via https://www.nature.com/articles/s41587-025-02636-6)
Real-time surveillance of viral genomes enables the detection of new variants, the assessment of their impact on infectivity and disease severity, the estimation of rates of spread and routes of transmission ... Jindal, M., Stone, H., Lim, S., & MacIntyre, C. R. A Geospatial Perspective Toward the Role of Wild Bird Migrations and Global Poultry Trade in the Spread of Highly Pathogenic Avian Influenza H5N1. GeoHealth, 9, e2024GH001296. Abstract
submitted by kickingbird at Mar, 26, 2025 from GeoHealth, 9, e2024GH001296 (via https://agupubs.onlinelibrary.wiley.com/doi/10.1029/2024GH00)
This study presents the interplay between wild bird migrations and global poultry trade in the unprecedented spread of highly pathogenic avian influenza, particularly the H5N1 clade 2.3.4.4b strain, across ... Ronja Piesche, etc.,al. [preprint]Immunogenicity and Protective Efficacy Against Highly Pathogenic Avian Influenza Virus H5N1, Clade 2.3.4.4b, in Fattening Geese. https://doi.org/10.20944/preprints202503.0731.v1. Abstract
submitted by kickingbird at Mar, 26, 2025 from https://doi.org/10.20944/preprints202503.0731.v1 (via https://www.preprints.org/manuscript/202503.0731/v1)
Background/Objectives: The risk of introduction of highly pathogenic avian influenza virus (HPAIV) in geese breeding and fattening flocks is heightened due to the necessity of free-range access to grazing ... Iwatsuki-Horimoto K, Uraki R, Ito M, Wang T, Guan. Transmission of bovine H5N1 virus in a hamster model. J Virol. 2025 Mar 25:e0014725. Abstract
submitted by kickingbird at Mar, 26, 2025 from J Virol. 2025 Mar 25:e0014725 (via https://journals.asm.org/doi/10.1128/jvi.00147-25)
Transmission among mammals of bovine highly pathogenic avian influenza (HPAI) H5N1 viruses, which have caused outbreaks in US dairy cattle, has been demonstrated in ferrets by our group (4, 5) and the ... Li X, Li A, Qu F, Li Y, Chen F, Lv X, An Q, Fei M,. Evaluation of Global Distribution, Genetic Evolution, and Mammalian Infectivity and Pathogenicity of H13 and H16 Avian Influenza Viruses. Emerg Microbes Infect. 2025 Mar 25:2482695. Abstract
submitted by kickingbird at Mar, 26, 2025 from Emerg Microbes Infect. 2025 Mar 25:2482695 (via https://pubmed.ncbi.nlm.nih.gov/40130325/)
H13 and H16 subtype avian influenza viruses (AIVs) typically infect Charadriiformes, are widely distributed throughout coastal regions worldwide, and pose a risk of spillover to mammals. Systematic research ... Liu CC, Ru YX, Li HR, Liu DJ, Liu JY, Zhao SL, Wu. Soluble influenza H3 trimer proteins enhance the breadth and potency of antibody response. Int J Biol Macromol. 2025 Mar 19;307(Pt 4):142240. Abstract
submitted by kickingbird at Mar, 25, 2025 from Int J Biol Macromol. 2025 Mar 19;307(Pt 4):142240 (via https://www.sciencedirect.com/science/article/abs/pii/S01418)
Seasonal influenza poses a continuing threat to public health. The effectiveness of the influenza vaccine varies across seasons, with protection against H3N2 being notably less reliable. A primary contributor ... Sen TK, Jing L, Anand A, Zhang Ryan LZ, Ting HT, H. Unique Immune and Other Responses of Human Nasal Epithelial Cells Infected with H5N1 Avian Influenza Virus Compared to Seasonal Human Influenza A and B Viruses. Emerg Microbes Infect. 2025 Mar 24:2484330. Abstract
submitted by kickingbird at Mar, 25, 2025 from Emerg Microbes Infect. 2025 Mar 24:2484330 (via https://pubmed.ncbi.nlm.nih.gov/40126073/)
Highly pathogenic avian influenza (HPAI) virus (e.g. H5N1) infects the lower airway to cause severe infections, and constitute a prime candidate for the emergence of disease X. The nasal epithelium is ... Nicole Lenz-Ajuh, etc.,al. [preprint]Impact of pH and temperature in dairy processing on the infectivity of H5N1 avian influenza viruses. https://doi.org/10.1101/2025.03.21.644501. Abstract
submitted by kickingbird at Mar, 23, 2025 from https://doi.org/10.1101/2025.03.21.644501 (via https://www.biorxiv.org/content/10.1101/2025.03.21.644501v1)
Highly pathogenic avian influenza viruses (HPAIV) of subtype H5N1 (clade 2.3.4.4b) have crossed the species barrier and caused a mastitis-like infection in dairy cows. The high levels of infectious virus ... Amber L Pillar, etc.,al. [preprint]Crucial role for iron metabolism in mediating influenza A virus infection and associated disease. https://doi.org/10.1101/2025.03.20.644262. Abstract
submitted by kickingbird at Mar, 23, 2025 from https://doi.org/10.1101/2025.03.20.644262 (via https://www.biorxiv.org/content/10.1101/2025.03.20.644262v1)
Rationale and Objectives: Iron availability and metabolism are important in the pathogenesis of bacterial infections. More recently, links have been reported between iron and the severity of viral infections. ... 6469 items, 20/Page, Page[32/324][|<<] [|<] [31] [32] [33] [34] [35] [36] [37] [38] [39] [40] [>|] [>>|] |
Related Pages:
Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!
|
- 
