Qiong Zhang, etc.,al. [preprint]Preclinical Evaluation of an mRNA Vaccine Developed from the First Human Isolate of Bovine H5N1. https://doi.org/10.21203/rs.3.rs-6758243/v1. Abstract
submitted by kickingbird at May, 31, 2025 from https://doi.org/10.21203/rs.3.rs-6758243/v1 (via https://www.researchsquare.com/article/rs-6758243/v1)
Given the ongoing global health threat posed by the zoonotic emergence of H5N1 clade 2.3.4.4b highly pathogenic avian influenza (HPAI), there is an urgent need for the rapid development of effective vaccines. ... Hassan M, Kaifer B, Christian T, Quaas XT, Mueller. First contact: an interdisciplinary guide into decoding H5N1 influenza virus interactions with glycosaminoglycans in 3D respiratory cell models. Front Cell Infect Microbiol. 2025 May 15;15:159695. Abstract
submitted by kickingbird at May, 30, 2025 from Front Cell Infect Microbiol. 2025 May 15;15:159695 (via https://www.frontiersin.org/journals/cellular-and-infection-)
The human respiratory system is vulnerable to viral infections. The influenza virus family alone accounts for one billion reported cases annually, some of which are severe and can be fatal. Among these, ... Nabeshima, K., Asakura, S., Sakoda, Y. et al. Novel host factors associated with resistance to highly pathogenic avian influenza in wild birds inferred from primary cell culture. Sci Rep 15, 18809 (2025). Abstract
submitted by kickingbird at May, 30, 2025 from Sci Rep 15, 18809 (2025) (via https://www.nature.com/articles/s41598-025-01316-4)
Bird species differ in the sensitivity to the highly pathogenic avian influenza virus (HPAIV). Here, we infected fibroblasts from 11 bird species with the H5N1 HPAIV strain A/chicken/Yamaguchi/7/2004. ... Cao L, Wang T, Ren P, Cheng C, Mao H, Hui X, Lin X. Viral polymerase-host interaction analysis reveals that the association between avian NUP93 and PB1 promotes H5N6 avian influenza virus replication. Microbiol Spectr 0:e03120-24. Abstract
submitted by kickingbird at May, 30, 2025 from Microbiol Spectr 0:e03120-24 (via https://journals.asm.org/doi/10.1128/spectrum.03120-24)
The H5N6 avian influenza virus, a highly pathogenic strain, poses a significant threat to poultry production and public health. The RNA-dependent RNA polymerase (comprising PB1, PB2, and PA proteins) and ... Cong He, etc.,al. A G219A hemagglutinin substitution increases pathogenicity and viral replication of Eurasian avian-like H1N1 swine influenza viruses. Veterinary Microbiology. Abstract
submitted by kickingbird at May, 30, 2025 from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
The Eurasian avian-like swine (EA) H1N1 virus has been widely prevalent in the Chinese swine population and has caused infections in human. However, knowledge regarding its pathogenic mechanisms remains ... Seiler P, Kaplan BS, Brice DC, Duan S, Li L, McGar. Altered germinal center responses in mice vaccinated with highly pathogenic avian influenza A(H5N1) virus. Vaccine. 2025 May 27;60:127311. Abstract
submitted by kickingbird at May, 30, 2025 from Vaccine. 2025 May 27;60:127311 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Highly pathogenic avian influenza (HPAI) H5N1 virus vaccines typically yield lower neutralizing antibody titers in animals than influenza A virus (IAV) vaccines derived from other viral subtypes. To understand ... Jenna Schafers, etc.,al. [preprint]Stability of influenza viruses in the milk of cows and sheep. https://doi.org/10.1101/2025.05.28.25328508. Abstract
submitted by kickingbird at May, 29, 2025 from https://doi.org/10.1101/2025.05.28.25328508 (via https://www.medrxiv.org/content/10.1101/2025.05.28.25328508v)
In late 2023, H5N1 high pathogenicity avian influenza (HPAIV) started circulating in dairy cattle in the USA. High viral titres were detected in milk from infected cows, raising concerns about onwards ... Goldin, K., van Tol, S., Johnson, R.C. et al. Enhanced neurotropism of bovine H5N1 compared to the Vietnam H5N1 isolate in C57BL/6J mice. npj Viruses 3, 43 (2025). Abstract
submitted by kickingbird at May, 29, 2025 from npj Viruses 3, 43 (2025) (via https://www.nature.com/articles/s44298-025-00121-0)
In this study, we investigated differences in tissue tropism of two HPAI H5N1 strains, the isolate A/Vietnam/1203/2004 (VN1203) isolated from a fatal human case in 2004 and the bovine isolate A/Bovine/Ohio/B24osu-342/2024 ... Maeve Louise Farrell, etc.,al. [preprint]Avian Influenza in Ireland: A Spatiotemporal, Subtype, and Host-Based Analysis (1983-2024). https://doi.org/10.1101/2025.05.26.656175. Abstract
submitted by kickingbird at May, 28, 2025 from https://doi.org/10.1101/2025.05.26.656175 (via https://www.biorxiv.org/content/10.1101/2025.05.26.656175v1)
Avian influenza virus (AIV) is a significant global concern, causing widespread mortality in wild birds, domestic poultry and most recently wild and domestic mammals. This study presents a retrospective ... Ralph E.V. Vanstreels, etc.,al. [preprint]Novel Highly Pathogenic Avian Influenza (A)H5N1 Triple Reassortant in Argentina, 2025. https://doi.org/10.1101/2025.05.23.655175. Abstract
submitted by kickingbird at May, 28, 2025 from https://doi.org/10.1101/2025.05.23.655175 (via https://www.biorxiv.org/content/10.1101/2025.05.23.655175v1)
Genomic sequencing of re-emerging highly pathogenic avian influenza A(H5N1) virus detected in Argentina in February 2025 revealed novel triple-reassortant viruses containing gene segments from Eurasian ... Muawan, L., Takada, K., Yoshimoto, S. et al. Characterization of A(H1N1)pdm09 influenza viruses isolated between 2016 and 2019. Npj Viruses. 2025 May 22;3(1):42. Abstract
submitted by kickingbird at May, 25, 2025 from Npj Viruses. 2025 May 22;3(1):42 (via https://www.nature.com/articles/s44298-025-00126-9)
The A(H1N1)pdm09 virus, which caused the 2009 influenza pandemic, has continued to circulate in humans for over a decade. Understanding its biological properties is crucial for effective surveillance, ... Grim R?mo, etc.,al. [preprint]Highly Pathogenic Avian Influenza A(H5N1) Caused Mass Death among Black-legged Kittiwakes (Rissa tridactyla) in Norway, 2023. https://doi.org/10.1101/2025.05.23.655725. Abstract
submitted by kickingbird at May, 25, 2025 from https://doi.org/10.1101/2025.05.23.655725 (via https://www.biorxiv.org/content/10.1101/2025.05.23.655725v1)
In 2023, highly pathogenic avian influenza (HPAI) heavily affected gulls in Europe. In July, a mass mortality event was reported in the Black-legged Kittiwake (Rissa tridactyla) breeding colony at Ekker?y ... AL-Eitan LN, Almahdawi DL, Khair IY. Phylogenetic Analysis and Spread of HPAI H5N1 in Middle Eastern Countries Based on Hemagglutinin and Neuraminidase Gene Sequences. Viruses. 2025; 17(5):734. Abstract
submitted by kickingbird at May, 23, 2025 from Viruses. 2025; 17(5):734 (via https://www.mdpi.com/1999-4915/17/5/734)
Highly pathogenic avian influenza (HPAI) A/H5N1 viruses threaten animal and human health worldwide. The first documented cases in the Middle East were reported in 2005; however, despite extensive phylogenetic ... Bellido-Martín, B., Rijnink, W.F., Iervolino, M. e. Evolution, spread and impact of highly pathogenic H5 avian influenza A viruses. Nat Rev Microbiol (2025). Abstract
submitted by kickingbird at May, 23, 2025 from Nat Rev Microbiol (2025) (via https://link.springer.com/article/10.1038/s41579-025-01189-4)
Since their first detection in 1996, highly pathogenic avian influenza viruses with H5 haemagglutinin of the A/Goose/Guangdong/1/1996 (Gs/Gd) lineage have caused outbreaks in domestic and wild animals ... Allen JD, Medina JM, Thomas MH, Lynch A, Nelson R,. H3 hemagglutinin proteins optimized for 2018 to 2022 elicit neutralizing antibodies across panels of modern influenza A(H3N2) viruses. J Immunol. 2025 May 21:vkaf092. Abstract
submitted by kickingbird at May, 23, 2025 from J Immunol. 2025 May 21:vkaf092 (via https://academic.oup.com/jimmunol/advance-article-abstract/d)
Influenza A(H3N2) viruses are currently evolving faster than any other subtype of seasonal influenza. As a result, vaccine efficacy can vary widely from one year to the next, and the wild-type antigens ... Ding X, Ma Y, Li S, Liu J, Qin L, Wu A. Influenza virus reassortment patterns exhibit preference and continuity while uncovering cross-species transmission events. Brief Bioinform. 2025 May 1;26(3):bbaf233. Abstract
submitted by kickingbird at May, 23, 2025 from Brief Bioinform. 2025 May 1;26(3):bbaf233 (via https://academic.oup.com/bib/article/26/3/bbaf233/8140404)
Genomic reassortment is a key driver of influenza virus evolution and a major factor in pandemic emergence, as reassorted strains can exhibit significantly altered antigenicity. However, due to technical ... Alkie TN, Embury-Hyatt C, Signore AV, Baldwin F, H. Comparative pathogenicity of three A(H5N1) clade 2.3.4.4b HPAI viruses in blue-winged teal and transmission to domestic poultry. mSphere. 2025 May 22:e0002125. Abstract
submitted by kickingbird at May, 23, 2025 from mSphere. 2025 May 22:e0002125 (via https://journals.asm.org/doi/10.1128/msphere.00021-25)
Long-distance migratory ducks play a critical role in the maintenance and dissemination of A(H5N1) viruses. Comparative pathogenicity studies were conducted on blue-winged teal (BWTE; Anas discors) using ... X Wen, etc.,al. [preprint]Fatal infection of a novel canine/human reassortant H3N2 influenza A virus in the zoo-housed golden monkeys. https://doi.org/10.21203/rs.3.rs-6582619/v1. Abstract
submitted by kickingbird at May, 22, 2025 from https://doi.org/10.21203/rs.3.rs-6582619/v1 (via https://www.researchsquare.com/article/rs-6582619/v1)
Influenza A virus (IAV) is one of the most challenging pathogens that threaten human and animal health. In June 2022, seven golden monkeys (Rhinopithecus roxellanaes) developed flu-like symptoms in succession ... Kwon, T., Trujillo, J. D., Carossino, M., Machkove. Pathogenicity and transmissibility of bovine-derived HPAI H5N1 B3.13 virus in pigs. Emerg Microbes Infect. 2025 May 21:2509742. Abstract
submitted by kickingbird at May, 22, 2025 from Emerg Microbes Infect. 2025 May 21:2509742 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Since the first emergence of highly pathogenic avian influenza (HPAI) H5N1 viruses in dairy cattle, the virus has continued to spread, reaching at least 17 states and at least 950 dairy herds in the United ... Simmons HC, Finney J, Kotaki R, Adachi Y, Moseman. A protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface. mBio. 2025 May 20:e0089225. Abstract
submitted by kickingbird at May, 21, 2025 from mBio. 2025 May 20:e0089225 (via https://journals.asm.org/doi/10.1128/mbio.00892-25)
Influenza infection and vaccination impart strain-specific immunity that protects against neither seasonal antigenic variants nor the next pandemic. However, antibodies directed to conserved sites can ... 6604 items, 20/Page, Page[31/331][|<<] [|<] [31] [32] [33] [34] [35] [36] [37] [38] [39] [40] [>|] [>>|] |
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