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2025-12-5 16:15:59
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Facciuolo, A., Aubrey, L., Barron-Castillo, U. et. Dairy cows develop protective immunity against reinfection with bovine H5N1 influenza virus. Nat Microbiol (2025).  Abstract  
submitted by kickingbird at Apr, 18, 2025 from Nat Microbiol (2025) (via https://www.nature.com/articles/s41564-025-01998-6)
Infection of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b in dairy cows causes severe mastitis and milk production losses. Whether cows can develop protective immunity is unclear. Here ...

Qin SL, Bai HJ, Deng P, Wang YW, Ma SM, Zhang Y, J. Spatial-temporal evolution patterns of influenza incidence in plateau regions from 2009 to 2023. Front Public Health. 2025 Apr 2;13:1553715.  Abstract  
submitted by kickingbird at Apr, 18, 2025 from Front Public Health. 2025 Apr 2;13:1553715 (via https://www.frontiersin.org/journals/public-health/articles/)
Objectives: This study used (Geographic Information System) GIS technology to analyze the spatiotemporal distribution of influenza incidence in Qinghai from 2009 to 2023, based on influenza surveillance ...

Leda Bassit, etc.,al. [preprint]Towards diagnostic preparedness: detection of highly pathogenic avian influenza A(H5N1) in contrived nasal swab specimens using rapid antigen and point-of-care molecular tests. https://doi.org/10.1101/2025.04.15.25325613.  Abstract  
submitted by kickingbird at Apr, 18, 2025 from https://doi.org/10.1101/2025.04.15.25325613 (via https://www.medrxiv.org/content/10.1101/2025.04.15.25325613v)
Highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b was first detected in birds in the United States in 2021 and an ongoing outbreak in dairy cattle began in early 2024. At least 70 U.S. cases ...

Huang QJ, Kim R, Song K, Grigorieff N, Munro JB, S. Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryoelectron tomography. PNAS 2025 Apr 22;122(16):e2426427122.  Abstract  
submitted by kickingbird at Apr, 18, 2025 from PNAS 2025 Apr 22;122(16):e2426427122 (via https://www.pnas.org/doi/10.1073/pnas.2426427122)
Influenza viruses are enveloped, negative-sense single-stranded RNA viruses covered in a dense layer of glycoproteins. Hemagglutinin (HA) accounts for 80 to 90% of influenza glycoprotein and plays a role ...

Chengyao Zhang, Vicky J Fang, Kwok-Hung Chan, Gabr. Interplay Between Viral Shedding, Age, and Symptoms in Individual Infectiousness of Influenza Cases in Households. he Journal of Infectious Diseases, Volume 231.  Abstract  
submitted by kickingbird at Apr, 18, 2025 from he Journal of Infectious Diseases, Volume 231 (via https://academic.oup.com/jid/article-abstract/231/2/462/7743)
BackgroundUnderstanding factors affecting the infectiousness of influenza cases is crucial for disease prevention and control. Viral shedding is expected to correlate with infectiousness of cases, but ...

Mao J, Chu KB, Eom GD, Yoon KW, Heo SI, Kang HJ, K. Influenza A hemagglutinin virus-like particles confer protection against influenza B virus infection. Emerg Microbes Infect. 2025 Apr 15:2494702.  Abstract  
submitted by kickingbird at Apr, 17, 2025 from Emerg Microbes Infect. 2025 Apr 15:2494702 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Influenza A hemagglutinin (HA), neuraminidase, and/or M2e-containing virus-like particles (VLPs) induce immune responses that contribute to protection against multiple influenza A virus subtypes. In this ...

Moon J, Shim J, Kim E, Hwang E. MIFlu: Large Language Model-based Multimodal Influenza Forecasting Scheme. IEEE J Biomed Health Inform. 2025 Apr 15;PP.  Abstract  
submitted by kickingbird at Apr, 17, 2025 from IEEE J Biomed Health Inform. 2025 Apr 15;PP (via https://ieeexplore.ieee.org/document/10965883)
In order to minimize the impact of influenza on public health, accurate early forecasting is essential. Various deep-learning-based models have been proposed to predict future influenza occurrences by ...

Ríos Carrasco M, Lin TH, Zhu X, Gabarroca García A. The Q226L mutation can convert a highly pathogenic H5 2.3.4.4e virus to bind human-type receptors. PNAS 2025 Apr 22;122(16):e2419800122.  Abstract  
submitted by kickingbird at Apr, 17, 2025 from PNAS 2025 Apr 22;122(16):e2419800122 (via https://www.pnas.org/doi/10.1073/pnas.2419800122)
H5Nx viruses continue to wreak havoc in avian and mammalian species worldwide. The virus distinguishes itself by the ability to replicate to high titers and transmit efficiently in a wide variety of hosts ...

Jimenez C, Hoepner LA. Exploring Methods to Evaluate HPAI Transmission Risk in Iowa During Peak HPAI Incidence, February 2022~December 2023. Int J Environ Res Public Health. 2025 Mar 10;22(3).  Abstract  
submitted by kickingbird at Apr, 17, 2025 from Int J Environ Res Public Health. 2025 Mar 10;22(3) (via https://www.mdpi.com/1660-4601/22/3/400)
Highly pathogenic avian influenza (HPAI), H5N1 strain, began to circulate in the United States on 8 February 2022. The state of Iowa lost the most domestic poultry to HPAI from February 2022-December 2023. ...

Pittman Ratterree DC, Chitlapilly Dass S, Ndeffo-M. Estimating the risk of zoonotic transmission of swine influenza A variant during agricultural fairs in the United States: a mathematical modeling. Front Vet Sci. 2025 Apr 1;12:1523981.  Abstract  
submitted by kickingbird at Apr, 17, 2025 from Front Vet Sci. 2025 Apr 1;12:1523981 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Introduction: Agricultural fairs offer a unique interface between humans and swine. We investigate the transmissibility of influenza A variant from pigs to humans using epidemiological data from a 2011 ...

Katzner TE, Blackford AV, Donahue M, Gibbs SEJ, Le. Safety and Immunogenicity of Poultry Vaccine for Protecting Critically Endangered Avian Species against Highly Pathogenic Avian Influenza Virus, United States. Emerg Infect Dis. 2025 Jun.  Abstract  
submitted by kickingbird at Apr, 17, 2025 from Emerg Infect Dis. 2025 Jun (via https://wwwnc.cdc.gov/eid/article/31/6/24-1558_article)
In 2023, an outbreak of highly pathogenic avian influenza occurred among critically endangered California condors (Gymnogyps californianus), and >21 died. We evaluated safety, immunogenicity, vaccination ...

Takashita E, Morita H, Nagata S, Fujisaki S, Miura. Influenza A(H1N1)pdm09 Virus with Reduced Susceptibility to Baloxavir, Japan, 2024. Emerg Infect Dis. 2025 May.  Abstract  
submitted by kickingbird at Apr, 15, 2025 from Emerg Infect Dis. 2025 May (via https://wwwnc.cdc.gov/eid/article/31/5/24-1123_article)
Influenza A(H1N1)pdm09 virus carrying an I38N substitution was detected in an untreated teenager in Japan. The I38N mutant virus exhibited reduced susceptibility to baloxavir but remained susceptible to ...

Akhtar Z, Moa AM, Tan TC, Fr?bert O, Menzies R, Ma. Prevention of Cardiovascular Diseases with Standard-Dose Quadrivalent Influenza Vaccine in People Aged ≥50 Years in Australia During the 2017 A/H3N2 Epidemic. Vaccines. 2025; 13(4):407.  Abstract  
submitted by kickingbird at Apr, 15, 2025 from Vaccines. 2025; 13(4):407 (via https://www.mdpi.com/2076-393X/13/4/407)
Background: In Australia, 2017 was a severe A/H3N2 season and, therefore, we estimated the effectiveness of standard-dose quadrivalent influenza vaccine in preventing hospitalization for cardiovascular ...

Uhart, M.M., Vanstreels, R.E.T., Nelson, M.I. et a. Epidemiological data of an influenza A/H5N1 outbreak in elephant seals in Argentina indicates mammal-to-mammal transmission. Nat Commun 15, 9516 (2024).  Abstract  
submitted by kickingbird at Apr, 14, 2025 from Nat Commun 15, 9516 (2024) (via https://www.nature.com/articles/s41467-024-53766-5)
H5N1 high pathogenicity avian influenza virus has killed thousands of marine mammals in South America since 2022. Here we report epidemiological data and full genome characterization of clade 2.3.4.4b ...

Morris SE, Mathis SM, Reeves E, Chung JR, Borcheri. Modeling the Potential Impacts of Outpatient Antiviral Treatment in Reducing Influenza-Associated Hospitalizations in the United States. J Infect Dis. 2025 Apr 12:jiaf061.  Abstract  
submitted by kickingbird at Apr, 13, 2025 from J Infect Dis. 2025 Apr 12:jiaf061 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: Seasonal influenza causes an estimated 120 000 to 710 000 hospitalizations annually in the United States. Treatment with antiviral medications, such as oseltamivir, can reduce risks of hospitalization ...

Claudio Campagna, Richard Condit, etc.,al. Predicting Population Consequences of an Epidemic of High Pathogenicity Avian Influenza on Southern Elephant Seals. Marine Mammal Science.  Abstract  
submitted by kickingbird at Apr, 13, 2025 from Marine Mammal Science (via https://onlinelibrary.wiley.com/doi/10.1111/mms.70009)
The colony of southern elephant seals (Mirounga leonina) at Península Valdés (Argentina) grew by 0.9% from 2000 to 2022, reaching a population of 18,000 reproductive females. In 2023, an epidemic of the ...

Juan Li, Bingxin Nie, etc.,al. Modelling for assessing the compulsory vaccination strategy against highly pathogenic avian influenza in a poultry farm of China. Applied Mathematical Modelling.  Abstract  
submitted by kickingbird at Apr, 13, 2025 from Applied Mathematical Modelling (via https://www.sciencedirect.com/science/article/pii/S0307904X2)
The prevalence of highly pathogenic avian influenza (HPAI) has become substantial obstacles for the poultry industry and international trade with potential threat to human health. We developed a data-driven ...

Adu OF, Sempere Borau M, Früh SP, Karakus U, Weich. Cell binding, uptake, and infection of influenza A virus using recombinant antibody-based receptors. J Virol. 2025 Apr 10:e0227524.  Abstract  
submitted by kickingbird at Apr, 13, 2025 from J Virol. 2025 Apr 10:e0227524 (via https://journals.asm.org/doi/10.1128/jvi.02275-24)
Human and avian influenza A viruses bind to sialic acid (Sia) receptors on cells as their primary receptors, and this results in endocytic uptake of the virus. While the role of Sia on glycoproteins and/or ...

Zhang X, Zhou Q, Bu S, Yang Y, Wang L, Xu C, Hao Z. A lateral flow biosensor based on duplex-specific nuclease and novel isothermal amplification for detection of influenza virus. Enzyme Microb Technol. 2025 Apr 7;188:110653.  Abstract  
submitted by kickingbird at Apr, 13, 2025 from Enzyme Microb Technol. 2025 Apr 7;188:110653 (via https://www.sciencedirect.com/science/article/abs/pii/S01410)
Here, we describe a lateral flow biosensor capable of detecting H1N1 virus by integrating duplex-specific nuclease (DSN) and a novel isothermal amplification, two probe isothermal amplification (TPIA). ...

Alene KA, Moore HC, Clements ACA, Gilmour B, Barth. Spatiotemporal patterns of influenza in Western Australia. Public Health Pract (Oxf). 2025 Mar 15;9:100602.  Abstract  
submitted by kickingbird at Apr, 12, 2025 from Public Health Pract (Oxf). 2025 Mar 15;9:100602 (via https://www.sciencedirect.com/science/article/pii/S266653522)
Background: Understanding the geospatial distribution of influenza infection and the risk factors associated with infection clustering can inform targeted preventive interventions. We conducted a geospatial ...

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