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H. Nedland, etc.,al. Serological evidence for the co-circulation of two lineages of influenza D viruses in equine populations of the Midwest United States. Zoonoses Public Health,2018 Feb 1.  Abstract  
submitted by kickingbird at Feb, 19, 2018 from Zoonoses Public Health,2018 Feb 1 (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5766371/)
Influenza D virus (IDV) is a newly described influenza type of the Orthomyxoviridae virus family that was first isolated from diseased swine in 2011 and has subsequently been detected in cattle around ...

Xiang D, Shen X, Pu Z, Irwin DM, et al. Convergent Evolution of Human-Isolated H7N9 Avian Influenza A Viruses. J Infect Dis 2018 Feb 9.  Abstract  
submitted by kickingbird at Feb, 19, 2018 from J Infect Dis 2018 Feb 9 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29438519/)
Background: Avian influenza A virus (AIV) H7N9 has caused five epidemic waves of human infections in China since 2013. AIVs may face strong selection to adapt to novel conditions when establishing themselves ...

Anderson AM, Baranowska-Hustad M, Braathen R, Grod. Simultaneous Targeting of Multiple Hemagglutinins to APCs for Induction of Broad Immunity against Influenza. J Immunol 2018 Feb 2.  Abstract  
submitted by kickingbird at Feb, 19, 2018 from J Immunol 2018 Feb 2 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29427414/)
There is a need for vaccines that can confer broad immunity against highly diverse pathogens, such as influenza. The efficacy of conventional influenza vaccines is dependent on accurate matching of vaccines ...

Coates BM, Staricha KL, Koch CM, Cheng Y, et al. Inflammatory Monocytes Drive Influenza A Virus-Mediated Lung Injury in Juvenile Mice. Immunol 2018 Feb 14.  Abstract  
submitted by kickingbird at Feb, 19, 2018 from Immunol 2018 Feb 14 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29445006/)
Healthy children are more likely to die of influenza A virus (IAV) infection than healthy adults. However, little is known about the mechanisms underlying the impact of young age on the development of ...

White KM, Ayllon J, Mena I, Potenski A, et al. Influenza B virus reverse genetic backbones with improved growth properties in the EB66 cell line as basis for vaccine seed virus generation. Vaccine 2018;36:1146-1153.  Abstract  
submitted by kickingbird at Feb, 11, 2018 from Vaccine 2018;36:1146-1153 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29395518/)
Vaccination remains the best available prophylaxis to prevent influenza virus infections, yet current inadequacies in influenza virus vaccine manufacturing often lead to vaccine shortages at times when ...

Westcott MM, Clemens EA, Holbrook BC, King SB, et. The choice of linker for conjugating R848 to inactivated influenza virus determines the stimulatory capacity for innate immune cells. Vaccine 2018;36:1174-1182..  Abstract  
submitted by kickingbird at Feb, 11, 2018 from Vaccine 2018;36:1174-1182. (via https://www.ncbi.nlm.nih.gov/m/pubmed/29398273/)
Inactivated influenza vaccines are not approved for use in infants less than 6?months of age due to poor immunogenicity in that population. While the live attenuated influenza vaccine has the potential ...

Li H, Bradley KC, Long JS, Frise R, Ashcroft JW, H. Internal genes of a highly pathogenic H5N1 influenza virus determine high viral replication in myeloid cells and severe outcome of infection in mice. PLoS Pathog 14(1): e1006821.  Abstract  
submitted by kickingbird at Feb, 1, 2018 from PLoS Pathog 14(1): e1006821 (via http://journals.plos.org/plospathogens/article?id=10.1371/jo)
The highly pathogenic avian influenza (HPAI) H5N1 influenza virus has been a public health concern for more than a decade because of its frequent zoonoses and the high case fatality rate associated with ...

Anne Pohlmann,etc.,al. Swarm incursions of reassortants of highly pathogenic avian influenza virus strains H5N8 and H5N5, clade 2.3.4.4b, Germany, winter 2016/17. Scientific Reportsvolume 8, Article number: 15 (20.  Abstract  
submitted by kickingbird at Feb, 1, 2018 from Scientific Reportsvolume 8, Article number: 15 (20 (via https://www.nature.com/articles/s41598-017-16936-8)
The outbreak of highly pathogenic avian influenza H5Nx viruses in winter 2016/2017 was the most severe HPAI epizootic ever reported in Germany. The H5N8 and H5N5 viruses detected in birds in Germany in ...

Shaoxia Lu,etc.,al. Genetics, pathogenicity and transmissibility of novel reassortant H5N6 highly pathogenic avian influenza viruses first isolated from migratory birds in western China. Emerging Microbes & Infections 7, Article number:.  Abstract  
submitted by kickingbird at Feb, 1, 2018 from Emerging Microbes & Infections 7, Article number: (via https://www.nature.com/articles/s41426-017-0001-1)
Novel H5N6 viruses were first documented in Laos in 2013 and subsequently reported in Vietnam and China1, but these viruses did not initially attract a great deal of attention. Instead, there was a greater ...

Marjolein J. Poen,etc.,al. Local amplification of highly pathogenic avian influenza H5N8 viruses in wild birds in the Netherlands, 2016 to 2017. Euro Surveill. 2018;23(4):pii=17-00449..  Abstract  
submitted by kickingbird at Feb, 1, 2018 from Euro Surveill. 2018;23(4):pii=17-00449. (via http://www.eurosurveillance.org/content/10.2807/1560-7917.ES)
Highly pathogenic avian influenza (HPAI) viruses of the H5 subtype, originating from the A/Goose/Guangdong/1/1996 (GsGd) lineage, have been circulating continuously in poultry in south-east Asia since ...

Beerens N, Koch G, Heutink R, Harders F, Vries DPE. Novel Highly Pathogenic Avian Influenza A(H5N6) Virus in the Netherlands, December 2017. Emerg Infect Dis. 2018 Apr.  Abstract  
submitted by kickingbird at Feb, 1, 2018 from Emerg Infect Dis. 2018 Apr (via https://wwwnc.cdc.gov/eid/article/24/4/17-2124_article)
A novel highly pathogenic avian influenza A(H5N6) virus affecting wild birds and commercial poultry was detected in the Netherlands in December 2017. Phylogenetic analysis demonstrated that the virus is ...

Kosik I, Ince WL, Gentles LE, Oler AJ, Kosikova M,. Influenza A virus hemagglutinin glycosylation compensates for antibody escape fitness costs. PLoS Pathog 14(1): e1006796..  Abstract  
submitted by kickingbird at Feb, 1, 2018 from PLoS Pathog 14(1): e1006796. (via http://journals.plos.org/plospathogens/article?id=10.1371/jo)
Rapid antigenic evolution enables the persistence of seasonal influenza A and B viruses in human populations despite widespread herd immunity. Understanding viral mechanisms that enable antigenic evolution ...

Xue R, Tian Y, Hou T, et al. H9N2 influenza virus isolated from minks has enhanced virulence in mice. Transbound Emerg Dis. 2018;00:1–7.  Abstract  
submitted by kickingbird at Feb, 1, 2018 from Transbound Emerg Dis. 2018;00:1–7 (via http://onlinelibrary.wiley.com/doi/10.1111/tbed.12805/full)
H9N2 is one of the major subtypes of influenza virus circulating in poultry in China, which has a wide host range from bird to mammals. Two H9N2 viruses were isolated from one mink farm in 2014. Phylogenetic ...

Kwong JC, Schwartz KL, Campitelli MA, Chung H, et. Acute Myocardial Infarction after Laboratory-Confirmed Influenza Infection. N Engl J Med 2018;378:345-353.  Abstract  
submitted by kickingbird at Jan, 28, 2018 from N Engl J Med 2018;378:345-353 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29365305/)
BACKGROUND: Acute myocardial infarction can be triggered by acute respiratory infections. Previous studies have suggested an association between influenza and acute myocardial infarction, but those studies ...

Read + Share Maemura T, Fukuyama S, Sugita Y, Lope. Lung-derived exosomal miR-483-3p regulates the innate immune response to influenza virus infection. J Infect Dis 2018 Jan 24.  Abstract  
submitted by kickingbird at Jan, 28, 2018 from J Infect Dis 2018 Jan 24 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29373693/)
Exosomes regulate cell-cell communication by transferring functional proteins and RNAs between cells. Here, to clarify the function of exosomes during influenza virus infection, we characterized lung-derived ...

Koo BS, Kim HK, Song D, Na W, et al. Virological and pathological characterization of an avian H1N1 influenza A virus. Arch Virol 2018 Jan 24.  Abstract  
submitted by kickingbird at Jan, 28, 2018 from Arch Virol 2018 Jan 24 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29368065/)
Gene segments from avian H1N1 influenza A viruses have reassorted with other influenza viruses to generate pandemic strains over the past century. Nevertheless, little effort has been invested in understanding ...

Lee YN, Lee EK, Song BM, Heo GB, et al. Evaluation of the zoonotic potential of multiple subgroups of clade 2.3.4.4 influenza A (H5N8) virus. Virology 2018;516:38-45.  Abstract  
submitted by kickingbird at Jan, 21, 2018 from Virology 2018;516:38-45 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29324360/)
Clade 2.3.4.4 H5N8 highly pathogenic avian influenza viruses (HPAIVs) have spread worldwide. Phylogenetic analysis identified two genetic groups of the H5N8 HPAIVs in South Korea; group A evolved further ...

Creager HM, Kumar A, Zeng H, Maines TR, et al. Infection and replication of influenza virus at the ocular surface. J Virol 2018 Jan 10.  Abstract  
submitted by kickingbird at Jan, 21, 2018 from J Virol 2018 Jan 10 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29321303/)
Though influenza viruses typically cause respiratory tract disease, some viruses, particularly those with an H7 hemagglutinin, have been isolated from the eyes of conjunctivitis cases. Previous work has ...

Aydillo T, Ayllon J, Pavlisin A, Martinez-Romero C. Specific mutations in the PB2 protein of influenza A virus compensate for the lack of efficient IFN antagonism of the NS1 protein of bat influenza A-like viruses. J Virol 2018 Jan 10.  Abstract  
submitted by kickingbird at Jan, 21, 2018 from J Virol 2018 Jan 10 (via https://www.ncbi.nlm.nih.gov/m/pubmed/29321309/)
Recently, two new influenza A-like viruses have been discovered in bats, HL17NL10 and HL18NL11. The hemagglutinin-like (HL) and neuraminidase like (NL) proteins of these viruses lack hemagglutination and ...

Nakatsu S, Murakami S, Shindo K, Horimoto T, et al. Influenza C and D viruses package eight organized ribonucleoprotein complexes. J Virol 2018 Jan 10..  Abstract  
submitted by kickingbird at Jan, 21, 2018 from J Virol 2018 Jan 10. (via https://www.ncbi.nlm.nih.gov/m/pubmed/29321324/)
Influenza A and B viruses have eight-segmented, single-stranded, negative-sense RNA genomes, whereas influenza C and D viruses have seven-segmented genomes. Each genomic RNA segment exists in the form ...

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