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Xiang N. et al. Sero-epidemiologic study of influenza A(H7N9) infection among exposed populations, China 2013~2014. Influenza Other Respir Viruses. 2016 Oct 20.  Abstract  
submitted by kickingbird at Nov, 4, 2016 from Influenza Other Respir Viruses. 2016 Oct 20 (via http://onlinelibrary.wiley.com/doi/10.1111/irv.12435/pdf)
Background The first human infections of novel avian influenza A(H7N9) virus were identified in China in March 2013. Sentinel surveillance systems and contact tracing may not identify mild and asymptomatic ...

Liu WJ. et al.. Cross-Immunities against Avian Influenza H7N9 Virus in the Healthy Population Affected by Antigenicity-Dependent Substitutions. J Infect Dis. 2016 Oct 12. pii: jiw471.  Abstract  
submitted by kickingbird at Nov, 4, 2016 from J Infect Dis. 2016 Oct 12. pii: jiw471 (via http://jid.oxfordjournals.org/content/early/2016/10/12/infdi)
Background.?The emergence of infections by the novel avian influenza A (H7N9) virus has posed a threat to human health. Cross-immunity between H7N9 and other heterosubtypic influenza viruses affected by ...

Komeda T. et al. Post-marketing safety evaluation of the intravenous anti-influenza neuraminidase inhibitor peramivir: A drug-use investigation in patients with high risk factors. J Infect Chemother. 2016 Oct;22(10):677-84.  Abstract  
submitted by kickingbird at Nov, 4, 2016 from J Infect Chemother. 2016 Oct;22(10):677-84 (via http://www.jiac-j.com/article/S1341-321X(16)30108-8/fulltext)
Peramivir, the only injectable anti-influenza neuraminidase inhibitor medically available in Japan at present, is considered first-line treatment in patients with high risk factors for influenza exacerbation. ...

ELBAHESH H, Bergmann S, Russell CJ. Focal adhesion kinase (FAK) regulates polymerase activity of multiple influenza A virus subtypes. Virology. 2016 Oct 13;499:369-374..  Abstract  
submitted by kickingbird at Nov, 4, 2016 from Virology. 2016 Oct 13;499:369-374. (via https://www.ncbi.nlm.nih.gov/pubmed/27743963)
Influenza A viruses (IAVs) cause numerous pandemics and yearly epidemics resulting in ~500,000 annual deaths globally. IAV modulates cellular signaling pathways at every step of the infection cycle. Focal ...

YANG J, Atkins KE, Feng L, Pang M, et al. Seasonal influenza vaccination in China: Landscape of diverse regional reimbursement policy, and budget impact analysis. Vaccine. 2016 Nov 11;34(47):5724-5735.  Abstract  
submitted by kickingbird at Nov, 4, 2016 from Vaccine. 2016 Nov 11;34(47):5724-5735 (via https://www.ncbi.nlm.nih.gov/pubmed/27745951)
BACKGROUND: To explore the current landscape of seasonal influenza vaccination across China, and estimate the budget of implementing a national "free-at-the-point-of-care" vaccination program for priority ...

LIU WJ, Tan S, Zhao M, Quan C, et al. Cross-Immunities against Avian Influenza H7N9 Virus in the Healthy Population Affected by Antigenicity-Dependent Substitutions. J Infect Dis. 2016 Oct 12.  Abstract  
submitted by kickingbird at Nov, 4, 2016 from J Infect Dis. 2016 Oct 12 (via https://www.ncbi.nlm.nih.gov/pubmed/27738054)
BACKGROUND: ?The emergence of infections by the novel avian influenza A (H7N9) virus has posed a threat to human health. Cross-immunity between H7N9 and other heterosubtypic influenza viruses affected ...

SITARAS I, Rousou X, Peeters B, de Jong MC, et al. Mutations in the haemagglutinin protein and their effect in transmission of highly pathogenic avian influenza (HPAI) H5N1 virus in sub-optimally vaccinated chickens. Vaccine. 2016 Oct 8.  Abstract  
submitted by kickingbird at Nov, 4, 2016 from Vaccine. 2016 Oct 8 (via https://www.ncbi.nlm.nih.gov/pubmed/27729175)
BACKGROUND: Transmission of highly pathogenic avian influenza (HPAI) viruses in poultry flocks is associated with huge economic losses, culling of millions of birds, as well as human infections and deaths. ...

Sikkema RS, Freidl GS, de Bruin E, Koopmans M. Weighing serological evidence of human exposure to animal influenza viruses - a literature review. Euro Surveill. 2016;21(44):pii=30388.  Abstract  
submitted by kickingbird at Nov, 4, 2016 from Euro Surveill. 2016;21(44):pii=30388 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Assessing influenza A virus strains circulating in animals and their potential to cross the species barrier and cause human infections is important to improve human influenza surveillance and ...

K Shimizu, etc.,al. Seroevidence for High Prevalence of Subclinical Infection with Avian Influenza A(H5N1) Virus among Workers in a Live Poultry Market in Indonesia. J Infect Dis. October 15, 2016 214 (8).  Abstract  
submitted by kickingbird at Oct, 11, 2016 from J Infect Dis. October 15, 2016 214 (8) (via http://jid.oxfordjournals.org/content/early/2016/10/06/infdi)
Background.?In Indonesia, highly pathogenic avian influenza A(H5N1) virus has become endemic in poultry, and has caused sporadic deadly infections in human. Since 2012 we have conducted fixed-point surveillance ...

ISHIKAWA H, Fukui T, Ino S, Sasaki H, et al. Influenza virus infection causes neutrophil dysfunction through reduced G-CSF production and an increased risk of secondary bacteria infection in the lung. Virology. 2016 Sep 12;499:23-29..  Abstract  
submitted by kickingbird at Sep, 21, 2016 from Virology. 2016 Sep 12;499:23-29. (via http://www.ncbi.nlm.nih.gov/pubmed/27632562)
The immunological mechanisms of secondary bacterial infection followed by influenza virus infection were examined. When mice were intranasally infected with influenza virus A and then infected with P. ...

DEJESUS E, Costa-Hurtado M, Smith D, Lee DH, et al. Changes in adaptation of H5N2 highly pathogenic avian influenza H5 clade 2.3.4.4 viruses in chickens and mallards. Virology. 2016 Sep 12;499:52-64.  Abstract  
submitted by kickingbird at Sep, 21, 2016 from Virology. 2016 Sep 12;499:52-64 (via http://www.ncbi.nlm.nih.gov/pubmed/27632565)
H5N2 highly pathogenic avian influenza (HPAI) viruses caused a severe poultry outbreak in the United States (U.S.) during 2015. In order to examine changes in adaptation of this viral lineage, the infectivity, ...

PARK S, Lee I, Kim JI, Bae JY, et al.. Effects of HA and NA glycosylation pattern changes on the transmission of avian influenza A(H7N9) virus in guinea pigs. Biochem Biophys Res Commun. 2016 Sep 6.  Abstract  
submitted by kickingbird at Sep, 21, 2016 from Biochem Biophys Res Commun. 2016 Sep 6 (via http://www.amedeo.com/p2.php?id=27613087&s=flu&pm=6213b1b427)
Avian influenza H7N9 virus has posed a concern of potential human-to-human transmission by resulting in seasonal virus-like human infection cases. To address the issue of sustained human infection with ...

Zhou J, Wu J, Zeng X, Huang G, Zou L, Song Y, Gopi. Isolation of H5N6, H7N9 and H9N2 avian influenza A viruses from air sampled at live poultry markets in China, 2014 and 2015. Euro Surveill. 2016;21(35):pii=30331..  Abstract  
submitted by kickingbird at Sep, 5, 2016 from Euro Surveill. 2016;21(35):pii=30331. (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Zoonotic infections by avian influenza viruses occur at the human–poultry interface, but the modes of transmission have not been fully investigated. We assessed the potential for airborne and fomite transmission ...

SULTAN S, Bui VN, Hill NJ, Hussein IT, et al. Genetic characterization of H5N2 influenza viruses isolated from wild birds in Japan suggests multiple reassortment. Arch Virol. 2016 Aug 30.  Abstract  
submitted by kickingbird at Sep, 5, 2016 from Arch Virol. 2016 Aug 30 (via http://www.ncbi.nlm.nih.gov/pubmed/27573808)
Low-pathogenic avian influenza viruses (LPAIVs) of the H5 subtype can mutate to highly pathogenic forms, potentially destabilizing the poultry industry. Wild migratory birds are considered a natural reservoir ...

KWON B, Hong M. The Influenza M2 Ectodomain Regulates the Conformational Equilibria of the Transmembrane Proton Channel: Insights from Solid-State NMR. Biochemistry. 2016 Aug 29.  Abstract  
submitted by kickingbird at Sep, 5, 2016 from Biochemistry. 2016 Aug 29 (via http://www.ncbi.nlm.nih.gov/pubmed/27571210)
The influenza M2 protein is the target of the amantadine family of antiviral drugs, and its transmembrane (TM) domain structure and dynamics have been extensively studied. However, little is known about ...

FABRIZIO TP, Sun Y, Yoon SW, Jeevan T, et al. Virologic differences do not fully explain the diversification of swine influenza viruses in the United States. J Virol. 2016 Aug 31..  Abstract  
submitted by kickingbird at Sep, 5, 2016 from J Virol. 2016 Aug 31. (via http://www.ncbi.nlm.nih.gov/pubmed/27581984)
Abstract Influenza A(H1N1) viruses entered the US swine population following the 1918 pandemic and remained genetically stable for roughly 80 years. In 1998, there was an outbreak of influenza-like ...

HURT AC, Su YC, Aban M, Peck H, et al. Evidence for the introduction, reassortment and persistence of diverse influenza A viruses in Antarctica. J Virol. 2016 Aug 17..  Abstract  
submitted by kickingbird at Aug, 29, 2016 from J Virol. 2016 Aug 17. (via http://www.ncbi.nlm.nih.gov/pubmed/27535050)
Avian influenza virus (AIV) surveillance in Antarctica during 2013 revealed the prevalence of evolutionarily distinct influenza viruses of H11N2 subtype in Adélie penguins. Here we present results from ...

DEDIEGO ML, Nogales A, Lambert-Emo K, Martinez-Sob. An NS1 protein mutation (I64T) affects interferon responses and virulence of circulating H3N2 human influenza A viruses. J Virol. 2016 Aug 17.  Abstract  
submitted by kickingbird at Aug, 29, 2016 from J Virol. 2016 Aug 17 (via http://www.ncbi.nlm.nih.gov/pubmed/27535054)
Influenza NS1 protein is the main viral protein counteracting host innate immune responses, allowing the virus to efficiently replicate in interferon (IFN)-competent systems. In this manuscript, we analyzed ...

TENG Q, Xu D, Shen W, Liu Q, et al. A Single Mutation at Position 190 in Hemagglutinin Enhances Binding Affinity for Human Type Sialic Acid Receptor and Replication of H9N2 Avian Influenza Virus in Mice. J Virol. 2016 Aug 24..  Abstract  
submitted by kickingbird at Aug, 29, 2016 from J Virol. 2016 Aug 24. (via http://www.ncbi.nlm.nih.gov/pubmed/27558420)
H9N2 avian influenza virus (AIV) has an extended host range but the molecular basis underlying H9N2 AIV transmission to mammals remains unclear. We isolated more than 900 H9N2 AIVs in our 3-year surveillance ...

LIU L, Zeng X, Chen P, Deng G, et al.. Characterization of Clade 7.2 H5 Avian Influenza Viruses That Continue to Circulate in Chickens in China.. J Virol. 2016 Aug 24..  Abstract  
submitted by kickingbird at Aug, 29, 2016 from J Virol. 2016 Aug 24. (via http://www.ncbi.nlm.nih.gov/pubmed/27558424)
The H5N1 avian influenza viruses emerged in Southeast Asia in the later 20th century and have evolved into multiple phylogenetic clades based on their hemagglutinin (HA)-encoding genes. The clade 7.2 viruses ...

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