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2026-6-11 21:40:04
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Ma T, Nagy A, Xu G, Xin L, Bao D, Lu C, Niu S, Wu. RNA-Seq Analysis of Influenza A Virus-Induced Transcriptional Changes in Mice Lung and Its Possible Implications for the Virus Pathogenicity in Mice. Viruses. 2021 Oct 8;13(10):2031.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Viruses. 2021 Oct 8;13(10):2031 (via https://www.mdpi.com/1999-4915/13/10/2031)
The influenza A virus (IAV) is an important cause of respiratory disease worldwide. It is well known that alveolar epithelial cells are the target cells for the IAV, but there is relatively limited knowledge ...

Cáceres CJ, Rajao DS, Perez DR. Airborne Transmission of Avian Origin H9N2 Influenza A Viruses in Mammals. Viruses. 2021 Sep 24;13(10):1919.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Viruses. 2021 Sep 24;13(10):1919 (via https://www.mdpi.com/1999-4915/13/10/1919)
Influenza A viruses (IAV) are widespread viruses affecting avian and mammalian species worldwide. IAVs from avian species can be transmitted to mammals including humans and, thus, they are of inherent ...

Park MJ, Cha RM, Kye SJ, Lee YN, Kim NY, Baek YG,. Pathogenicity of H5N8 High Pathogenicity Avian Influenza Virus in Chickens and Ducks from South Korea in 2020-2021. Viruses. 2021 Sep 23;13(10):1903.  Abstract  
submitted by kickingbird at Oct, 27, 2021 from Viruses. 2021 Sep 23;13(10):1903 (via https://www.mdpi.com/1999-4915/13/10/1903)
During the 2020-2021 winter season, an outbreak of clade 2.3.4.4b H5N8 high pathogenicity avian influenza (HPAI) virus occurred in South Korea. Here, we evaluated the pathogenicity and transmissibility ...

Jang Y, Seo SH. H5 cleavage-site peptide vaccine protects chickens from lethal infection by highly pathogenic H5 avian influenza viruses. Arch Virol. 2021 Oct 25.  Abstract  
submitted by kickingbird at Oct, 26, 2021 from Arch Virol. 2021 Oct 25 (via https://link.springer.com/article/10.1007%2Fs00705-021-05284)
Highly pathogenic H5Nx avian influenza viruses constantly threaten the poultry industry and humans and have pandemic potential. These viruses continuously evolve, requiring a universal vaccine to protect ...

Kong X, Guan L, Shi J, Kong H, Zhang Y, Zeng X, Ti. A single-amino-acid mutation at position 225 in hemagglutinin attenuates H5N6 influenza virus in mice. Emerg Microbes Infect. 2021 Oct 22:1-21.  Abstract  
submitted by kickingbird at Oct, 26, 2021 from Emerg Microbes Infect. 2021 Oct 22:1-21 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
The highly pathogenic avian influenza H5N6 viruses are widely circulating in poultry and wild birds, and have caused 38 human infections including 21 deaths; however, the key genetic determinants of the ...

Zhao J, He W, Lu M, He H, Lai A. Emergence and Characterization of a Novel Reassortant Canine Influenza Virus Isolated from Cats. Pathogens. 2021 Oct 14;10(10):1320.  Abstract  
submitted by kickingbird at Oct, 26, 2021 from Pathogens. 2021 Oct 14;10(10):1320 (via https://www.mdpi.com/2076-0817/10/10/1320)
Cats are susceptible to a wide range of influenza A viruses (IAV). Furthermore, cats can serve as an intermediate host, and transfer avian influenza virus (AIV) H7N2 to a veterinarian. In this report, ...

Kang HJ, Chu KB, Yoon KW, Eom GD, Mao J, Kim MJ, L. Neuraminidase in Virus-like Particles Contributes to the Protection against High Dose of Avian Influenza Virus Challenge Infection. Pathogens. 2021 Oct 7;10(10):1291.  Abstract  
submitted by kickingbird at Oct, 26, 2021 from Pathogens. 2021 Oct 7;10(10):1291 (via https://www.mdpi.com/2076-0817/10/10/1291)
Neuraminidase is an important target for influenza vaccination. In this study, we generated avian influenza VLPs, expressing hemagglutinin (HA), neuraminidase (NA), HA and NA co-expressed (HANA), to evaluate ...

Mon HH, Hadrill D, Brioudes A, Mon CCS, Sims L, Wi. Longitudinal Analysis of Influenza A(H5) Sero-Surveillance in Myanmar Ducks, 2006-2019. Microorganisms. 2021 Oct 7;9(10):2114.  Abstract  
submitted by kickingbird at Oct, 26, 2021 from Microorganisms. 2021 Oct 7;9(10):2114 (via https://www.mdpi.com/2076-2607/9/10/2114)
Between 2006 and 2019, serological surveys in unvaccinated domestic ducks reared outdoors in Myanmar were performed, using a haemagglutination inhibition (HI) test, to confirm H5 avian influenza virus ...

Elshina E, Te Velthuis AJW. The influenza virus RNA polymerase as an innate immune agonist and antagonist. Cell Mol Life Sci. 2021 Oct 22:1–20.  Abstract  
submitted by kickingbird at Oct, 26, 2021 from Cell Mol Life Sci. 2021 Oct 22:1–20 (via https://link.springer.com/article/10.1007%2Fs00018-021-03957)
Influenza A viruses cause a mild-to-severe respiratory disease that affects millions of people each year. One of the many determinants of disease outcome is the innate immune response to the viral infection. ...

Chen C, Zhang X, Jiang D, Yan D, Guan Z, Zhou Y, L. Associations between Temperature and Influenza Activity: A National Time Series Study in China. Int J Environ Res Public Health. 2021 Oct 15;18(20.  Abstract  
submitted by kickingbird at Oct, 26, 2021 from Int J Environ Res Public Health. 2021 Oct 15;18(20 (via https://www.mdpi.com/1660-4601/18/20/10846)
Previous studies have reported that temperature is the main meteorological factor associated with influenza activity. This study used generalized additive models (GAMs) to explore the relationship between ...

Kou Z, Li J, Fan X, Kosari S, Qiang X. Predicting Cross-Species Infection of Swine Influenza Virus with Representation Learning of Amino Acid Features. Comput Math Methods Med. 2021 Oct 11;2021:6985008.  Abstract  
submitted by kickingbird at Oct, 23, 2021 from Comput Math Methods Med. 2021 Oct 11;2021:6985008 (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8523279/)
Swine influenza viruses (SIVs) can unforeseeably cross the species barriers and directly infect humans, which pose huge challenges for public health and trigger pandemic risk at irregular intervals. Computational ...

Rijks JM, Hesselink H, Lollinga P, Wesselman R, Pr. Highly Pathogenic Avian Influenza A(H5N1) Virus in Wild Red Foxes, the Netherlands, 2021. Emerg Infect Dis. 2021 Nov;27(11):2960-2962.  Abstract  
submitted by kickingbird at Oct, 23, 2021 from Emerg Infect Dis. 2021 Nov;27(11):2960-2962 (via https://wwwnc.cdc.gov/eid/article/27/11/21-1281_article)
We detected infection with highly pathogenic avian influenza A(H5N1) virus clade 2.3.4.4b in 2 red fox (Vulpes vulpes) cubs found in the wild with neurologic signs in the Netherlands. The virus is related ...

He G, Ming L, Li X, Song Y, Tang L, Ma M, Cui J, W. Genetically Divergent Highly Pathogenic Avian Influenza A(H5N8) Viruses in Wild Birds, Eastern China. Emerg Infect Dis. 2021;27(11):2940-2943.  Abstract  
submitted by kickingbird at Oct, 23, 2021 from Emerg Infect Dis. 2021;27(11):2940-2943 (via https://wwwnc.cdc.gov/eid/article/27/11/20-4893_article)
In late 2020, we detected 32 highly pathogenic avian influenza A(H5N8) viruses in migratory ducks in Shanghai, China. Phylogenetic analysis of 5 representative isolates identified 2 sublineages of clade ...

Su W, Sia SF, Choy KT, Ji Y, Chen D, Lau EHY, Fu G. Limited onward transmission potential of reassortment genotypes from chickens co-infected with H9N2 and H7N9 avian influenza viruses. Emerg Microbes Infect. 2021 Oct 19:1-36.  Abstract  
submitted by kickingbird at Oct, 21, 2021 from Emerg Microbes Infect. 2021 Oct 19:1-36 (via https://pubmed.ncbi.nlm.nih.gov/34666614/)
The segmented genome of influenza A virus has conferred significant evolutionary advantages to this virus through genetic reassortment, a mechanism that facilitates the rapid expansion of viral genetic ...

Mhamdi Z, Carbonneau J, Venable MC, Baz M, Abed Y,. Replication and transmission of an influenza A(H3N2) virus harboring the polymerase acidic I38T substitution, in guinea pigs. J Gen Virol. 2021 Oct;102(10).  Abstract  
submitted by kickingbird at Oct, 19, 2021 from J Gen Virol. 2021 Oct;102(10) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
The polymerase acidic (PA) I38T substitution is a dominant marker of resistance to baloxavir. We evaluated the impact of I38T on the fitness of a contemporary influenza A(H3N2) virus. Influenza A/Switzerland/9715293/2013 ...

Abolnik C, Ostmann E, Woods M, Wandrag DBR, Grewar. Experimental infection of ostriches with H7N1 low pathogenic and H5N8 clade 2.3.4.4B highly pathogenic influenza A viruses. Vet Microbiol. 2021 Oct 8;263:109251.  Abstract  
submitted by kickingbird at Oct, 19, 2021 from Vet Microbiol. 2021 Oct 8;263:109251 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Infection dynamics data for influenza A virus in a species is important for understanding host-pathogen interactions and developing effective control strategies. Seven-week-old ostriches challenged with ...

Zhang G, Ng F, Chen M. Short-hairpin RNAs delivered by recombinant adeno-associated virus inhibited the replication of influenza A viruses in vitro. Virology. 2021 Oct 11;564:46-52.  Abstract  
submitted by kickingbird at Oct, 19, 2021 from Virology. 2021 Oct 11;564:46-52 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Antiviral short-hairpin RNAs (shRNAs) delivered by recombinant adeno-associated virus (rAAV) were investigated for their potential prophylactic and therapeutic applications related to the influenza A virus ...

Bdeir N, Arora P, G?rtner S, P?hlmann S, Winkler M. Evidence that two instead of one defective interfering RNA in influenza A virus-derived defective interfering particles (DIPs) does not enhance antiviral activity. Sci Rep. 2021 Oct 14;11(1):20477.  Abstract  
submitted by kickingbird at Oct, 19, 2021 from Sci Rep. 2021 Oct 14;11(1):20477 (via https://www.nature.com/articles/s41598-021-99691-1)
Influenza A virus (IAV) infection constitutes a significant health threat. Defective interfering particles (DIPs) can arise during IAV infection and inhibit spread of wild type (WT) IAV. DIPs harbor defective ...

Alqazlan N, Emam M, Nagy é, Bridle B, Sargolzaei M. Transcriptomics of chicken cecal tonsils and intestine after infection with low pathogenic avian influenza virus H9N2. Sci Rep. 2021 Oct 14;11(1):20462.  Abstract  
submitted by kickingbird at Oct, 19, 2021 from Sci Rep. 2021 Oct 14;11(1):20462 (via https://www.nature.com/articles/s41598-021-99182-3)
Influenza viruses cause severe respiratory infections in humans and birds, triggering global health concerns and economic burden. Influenza infection is a dynamic process involving complex biological host ...

Kombiah S, Kumar M, Murugkar HV, Nagarajan S, Tosh. Role of expression of host cytokines in the pathogenesis of H9N2-PB2 reassortant and non-reassortant H5N1 avian influenza viruses isolated from crows in BALB/c mice. Microb Pathog. 2021 Oct 11;161(Pt A):105239.  Abstract  
submitted by kickingbird at Oct, 19, 2021 from Microb Pathog. 2021 Oct 11;161(Pt A):105239 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
The present experiment was conducted to study the role of cytokine, chemokine and TLRs responses of H9N2-PB2 reassortant H5N1 virus as compared to non-reassortant H5N1 virus isolated from crows in BALB/c ...

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