Fang C, Sun X, Feng Y, Song H, Wang S. PB1 mutations as key drivers of influenza A virus evolution. Front Microbiol. 2026 Jan 29;17:1768665. Abstract
submitted by kickingbird at Feb, 17, 2026 from Front Microbiol. 2026 Jan 29;17:1768665 (via https://www.frontiersin.org/journals/microbiology/articles/1)
Influenza A virus (IAV) is a zoonotic pathogen with a broad host range, posing an ongoing threat to global public health. As the core subunit of the IAV polymerase, polymerase basic protein 1 (PB1) is ... Cui J, Foo SSW, Kong WT, Lin C, Ampomah PB, Zharko. Irf7 Deficiency Confers Protection Against Influenza Infection, Independent of irf3. Int J Biol Sci. 2026 Jan 22;22(4):1974-1996. Abstract
submitted by kickingbird at Feb, 17, 2026 from Int J Biol Sci. 2026 Jan 22;22(4):1974-1996 (via https://www.ijbs.com/v22p1974.htm)
Interferon regulatory factors irf3 and irf7 are pivotal for antiviral immunity, yet their cell-type-specific contributions, particularly within macrophage and dendritic cell (DC) lineages, have not been ... Yang X, Gao Q, Xi Z, Zhao P, Zhao J. Prevalence and Heterogeneity of Swine Influenza Virus in China From 2010 to 2025: A Systematic Review and Meta-Analysis. Transbound Emerg Dis. 2026 Feb 13;2026:1096796. Abstract
submitted by kickingbird at Feb, 17, 2026 from Transbound Emerg Dis. 2026 Feb 13;2026:1096796 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/1096796)
Background: Swine influenza virus (SIV) is endemic in China, threatening the swine industry and public health. This meta-analysis estimated the national pooled prevalence of SIV (2010-2025) and identified ... Goujgoulova G, Stoimenov G, Koev K. Molecular Characterization of Highly Pathogenic Avian Influenza H5N1 Viruses Circulating in Bulgaria During 2024–2025: Evidence for Hidden Circulation and Zoonotic Risk Markers. International Journal of Molecular Sciences. 2026;. Abstract
submitted by kickingbird at Feb, 15, 2026 from International Journal of Molecular Sciences. 2026; (via https://www.mdpi.com/1422-0067/27/4/1711)
The highly pathogenic avian influenza virus HPAI A(H5N1) genotype AF was detected in southern Europe during the 2021/2022 season and spread widely. It emerged in Bulgaria in 2022/2023, mainly affecting ... Nguyen NMK, West AC, Ambrose RL, Tate MD. Dissecting Cell Death Pathways in Influenza A Virus Infection: Comparative Insights from Human Models. Viruses. 2026; 18(2):246. Abstract
submitted by kickingbird at Feb, 15, 2026 from Viruses. 2026; 18(2):246 (via https://www.mdpi.com/1999-4915/18/2/246)
Influenza A virus remains a major global health threat, causing annual epidemics and occasional pandemics. Programmed cell death, including apoptosis, pyroptosis, and necroptosis, with emerging evidence ... Ga E, Bae E, Xie X, Hwang J, Yeom M, Lim JW, Song. Acquisition of amantadine resistance via M gene reassortment in canine H3N2 influenza virus and elucidation of the resistance mechanism. Virol J. 2026 Feb 13. Abstract
submitted by kickingbird at Feb, 15, 2026 from Virol J. 2026 Feb 13 (via https://link.springer.com/article/10.1186/s12985-026-03097-2)
A novel variant of the canine influenza virus H3N2 (cH3N2), designated as the M variant, was identified as containing a matrix (M) gene segment derived from the 2009 pandemic H1N1 virus (pdmH1N1), raising ... Gai W, Wu S, Li B, Zhang Y, Wang Z, Teng Y, Luo G,. Pocket-Based Generative Diffusion Model Accelerates Potent Influenza A Hemagglutinin Inhibitor Discovery. J Med Chem. 2026 Feb 13. Abstract
submitted by kickingbird at Feb, 15, 2026 from J Med Chem. 2026 Feb 13 (via https://pubs.acs.org/doi/10.1021/acs.jmedchem.5c03787)
The deep generative model has recently advanced 3D chemical space exploration but overlooked the balance between target affinity and structural rationality, limiting their effectiveness in drug discovery. ... Neher RA, Huddleston J, Bedford T, Lewis NS, Harve. Nomenclature for Tracking of Genetic Variation of Seasonal Influenza Viruses. Influenza Other Respir Viruses. 2026 Feb;20(2):e70. Abstract
submitted by kickingbird at Feb, 15, 2026 from Influenza Other Respir Viruses. 2026 Feb;20(2):e70 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70230)
Background: Genomic surveillance of human seasonal influenza viruses is an essential component of the Global Influenza Surveillance and Response system (GISRS) and informs the recommendations for the seasonal ... Papkiauri A, Urushadze L, Tevdoradze T, Sidamonidz. Genomic-based biosurveillance for avian influenza: whole genome sequencing from wild mallards sampled during autumn migration in 2022-2023 reveals a high co-infection rate on migration stopover site i. Front Microbiol. 2026 Jan 28;17:1735728. Abstract
submitted by kickingbird at Feb, 13, 2026 from Front Microbiol. 2026 Jan 28;17:1735728 (via https://www.frontiersin.org/journals/microbiology/articles/1)
The Caucasus region, including Georgia, is an important intersection for migratory waterbirds, offering potential for avian influenza virus (AIV) transmission between populations from different geographic ... Leyson CM, Vargas-Maldonado N, Gaddy M, Raghunatha. Viral lineage and mode of exposure modulate within-host spatial dynamics of influenza A viruses in a guinea pig model. J Virol. 2026 Feb 12:e0188925. Abstract
submitted by kickingbird at Feb, 13, 2026 from J Virol. 2026 Feb 12:e0188925 (via https://journals.asm.org/doi/10.1128/jvi.01889-25)
The upper and lower respiratory tracts (URT and LRT) present distinct environments for influenza A virus (IAV) replication. Their differential features have major implications for viral evolutionary dynamics, ... Sanders CG, Liu M, Fusco JA, Ohl EM, Tarbuck NN, K. [preprint]Efficient replication of influenza D virus in the human airway underscores zoonotic potential. https://doi.org/10.64898/2026.02.07.704474. Abstract
submitted by kickingbird at Feb, 13, 2026 from https://doi.org/10.64898/2026.02.07.704474 (via https://www.biorxiv.org/content/10.64898/2026.02.07.704474v1)
Influenza D virus (IDV), primarily found in livestock species, has demonstrated cross-species transmission potential, yet its threat to humans remains poorly understood. Here, we curated a panel of IDV ... Gagandeep Singh, etc.,al. [preprint]Population immunity to clade 2.3.4.4b H5N1 is dominated by anti-neuraminidase antibodies. https://doi.org/10.64898/2026.02.10.26346014. Abstract
submitted by kickingbird at Feb, 13, 2026 from https://doi.org/10.64898/2026.02.10.26346014 (via https://www.medrxiv.org/content/10.64898/2026.02.10.26346014)
Clade 2.3.4.4b highly pathogenic avian influenza A(H5N1) viruses continue to expand geographically and across mammalian hosts, raising concern about pandemic potential. The degree and specificity of pre-existing ... Jiao J, Ding J, Sun Z, Chi C, Liu S, Jiang S, Chen. Characterization of a reassortant H3N2 swine influenza virus with 2009 pandemic internal genes and enhanced potential for zoonotic risk. Vet Microbiol. 2026 Feb 7;315:110937. Abstract
submitted by kickingbird at Feb, 13, 2026 from Vet Microbiol. 2026 Feb 7;315:110937 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Pigs serve as key "mixing vessels" for influenza A viruses, playing a critical role in cross-species transmission, while the H3N2 subtype represents an important lineage within the swine influenza virus ... Downey J, Oliveira-Coelho A, Kiss MG, Laghlali G,. Influenza hijacks myeloid cells to inflict type-I interferon-fueled damage in the heart. Immunity. 2026 Feb 9:S1074-7613(25)00567-9. Abstract
submitted by kickingbird at Feb, 12, 2026 from Immunity. 2026 Feb 9:S1074-7613(25)00567-9 (via https://www.cell.com/immunity/abstract/S1074-7613(25)00567-9)
Abundant evidence has correlated influenza infection with cardiovascular disease, yet mechanisms linking infection with the heart remain poorly understood. Here, we show that influenza infection damaged ... Cardenas M, Compton S, Caceres CJ, García-Sastre A. MHC class II functions as a host-specific entry receptor for representative human and swine H3N2 influenza A viruses. Nat Commun. 2026 Feb 10. Abstract
submitted by kickingbird at Feb, 12, 2026 from Nat Commun. 2026 Feb 10 (via https://www.nature.com/articles/s41467-026-69267-6)
Influenza A viruses (FLUAV) utilize sialic acid to enter host cells via the envelope's hemagglutinin (HA), and its affinity for host-specific sialic acid linkage configuration is a major host range determinant. ... Encinas P, Nogales A, Escribano-Romero E, Del Burg. Longitudinal Surveillance of Influenza A Virus Exposure in Wild Boars (Sus scrofa) in Spain (2015-2023): Serologic and Virologic Evidence of Subtype Infections and H5N1 Spillover Risk. Zoonoses Public Health. 2026 Feb 10. Abstract
submitted by kickingbird at Feb, 12, 2026 from Zoonoses Public Health. 2026 Feb 10 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.70040)
Introduction: Influenza A viruses (IAVs) are responsible for respiratory infections in a wide range of species, including birds, swine and humans. The role of wild boar (Sus scrofa) in IAV epidemiology ... Bjorn Koel, etc.,al. [preprint]Emergence and antigenic characterisation of influenza A(H3N2) viruses with hemagglutinin substitutions N158K and K189R during the 2024/25 influenza season. https://doi.org/10.64898/2026.02.10.704996. Abstract
submitted by kickingbird at Feb, 11, 2026 from https://doi.org/10.64898/2026.02.10.704996 (via https://www.biorxiv.org/content/10.64898/2026.02.10.704996v1)
Background Seasonal human influenza viruses can escape from antibody-mediated neutralization when amino acid changes occur in the hemagglutinin protein. Routine surveillance identified circulation of an ... Daiki Mori, Nicolas Sax, Nozomi Shimada, Mana Kuwa. Epitope specificity shapes the CD4+ T cell response to influenza virus infection in mice. International Immunology, 2026;, dxag008. Abstract
submitted by kickingbird at Feb, 11, 2026 from International Immunology, 2026;, dxag008 (via https://academic.oup.com/intimm/advance-article-abstract/doi)
Helper CD4+ T cells play a central role in orchestrating protective immune responses during infection and vaccination. Activation of na?ve CD4+ T cells is initiated by the recognition of antigenic peptides ... Lejeune M, Tornos J, Bralet T, De Pasquale C, Mar?. Vaccination against H5 HP avian influenza virus leads to persistent immune response in wild king penguins. Nat Commun. 2026 Feb 9;17(1):1395. Abstract
submitted by kickingbird at Feb, 10, 2026 from Nat Commun. 2026 Feb 9;17(1):1395 (via https://www.nature.com/articles/s41467-026-69094-9)
Since 2021, the panzootic nature of high pathogenicity avian influenza (HPAI) represents an increasing threat to wild vertebrate populations. In this context, recent vaccines developed for poultry could ... Ichikawa Y, Saito R, Chon I, Phyu WW, Kyaw Y, Win. Molecular Epidemiology and Genetic Diversity of Influenza B Viruses Based on Whole-Genome Analysis in Japan and Myanmar, 2016-2020. Influenza Other Respir Viruses. 2026 Feb;20(2):e70. Abstract
submitted by kickingbird at Feb, 10, 2026 from Influenza Other Respir Viruses. 2026 Feb;20(2):e70 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70234)
Background: Influenza B virus (IBV) contributes to seasonal epidemics, but its molecular evolution is less defined than influenza A. We analyzed IBVs collected in Japan and Myanmar (2016-2020) to investigate ... 6878 items, 20/Page, Page[13/344][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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