Ito Toshihiro. Pathogenicity and host range of avian influenza viruses: molecular determinants and virological perspectives. J Vet Med Sci. 2025 Sep 16. Abstract
submitted by kickingbird at Sep, 18, 2025 from J Vet Med Sci. 2025 Sep 16 (via https://www.jstage.jst.go.jp/article/jvms/advpub/0/advpub_25)
The pathogenicity of avian influenza virus (AIV) is governed primarily by the hemagglutinin (HA) glycoprotein. Highly pathogenic avian influenza viruses contain a highly cleavable HA molecule susceptible ... Di Genova C, Warren CJ, Johnson S, Riccio S, Roper. Pigeons exhibit low susceptibility and poor transmission capacity for H5N1 clade 2.3.4.4b high pathogenicity avian influenza virus. J Gen Virol. 2025 Sep;106(9). Abstract
submitted by kickingbird at Sep, 18, 2025 from J Gen Virol. 2025 Sep;106(9) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
The ongoing panzootic of H5N1 high pathogenicity avian influenza virus (HPAIV) has caused the deaths of over half a billion wild birds and poultry and has led to spillover events in both wild and domestic ... Sun X, Subbiah J, Belser JA, Brock N, Gansebom S,. Effect of Seasonal Influenza Vaccines on Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Ferrets. Emerg Infect Dis. 2025 Oct. Abstract
submitted by kickingbird at Sep, 18, 2025 from Emerg Infect Dis. 2025 Oct (via https://wwwnc.cdc.gov/eid/article/31/10/25-0668_article)
Highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b viruses have infected >1,000 herds of dairy cattle and hundreds of poultry flocks in the United States since the beginning of 2024. Seventy human ... Banyard AC, Coombes H, Terrey J, McGinn N, Seeking. Detection of clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus in a sheep in Great Britain, 2025. Emerg Microbes Infect. 2025 Dec;14(1):2547730. Abstract
submitted by kickingbird at Sep, 16, 2025 from Emerg Microbes Infect. 2025 Dec;14(1):2547730 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus (HPAIV) continues to pose a significant global threat, affecting wild and domestic avian, and mammalian species. In early 2024, H5N1 HPAIV was ... Eid S, Hagag NM, Mosaad Z, Bakry NR, Elhusseiny MH. Genomic surveillance and evolution of co-circulating avian influenza H5N1 and H5N8 viruses in Egypt, 2022-2024. Emerg Microbes Infect. 2025 Sep 15:2562046. Abstract
submitted by kickingbird at Sep, 16, 2025 from Emerg Microbes Infect. 2025 Sep 15:2562046 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
For over two decades, avian influenza virus (AIV) has significantly impacted the Egyptian poultry population, with multiple subtypes and genotypes contributing to significant economic and agricultural ... Chika Kikuchi, etc.,al. [preprint]H3N2 influenza virus tropism shifts to glycan receptors on tracheal ciliated cells. https://doi.org/10.1101/2025.09.12.675939. Abstract
submitted by kickingbird at Sep, 16, 2025 from https://doi.org/10.1101/2025.09.12.675939 (via https://www.biorxiv.org/content/10.1101/2025.09.12.675939v1)
Human H3N2 influenza viruses, introduced during the 1968 pandemic, have evolved to recognize human-type sialic acid-containing receptors (Neu5Acα2-6Gal) extended with at least three LacNAc (Galβ1-4GlcNAc) ... Lucas Stolle, etc.,al. [preprint]Divergent antibody-mediated population immunity to H5, H7 and H9 subtype potential pandemic influenza viruses. https://doi.org/10.1101/2025.09.08.25335309. Abstract
submitted by kickingbird at Sep, 16, 2025 from https://doi.org/10.1101/2025.09.08.25335309 (via https://www.medrxiv.org/content/10.1101/2025.09.08.25335309v)
Influenza continues to cause significant mortality globally and possesses substantial pandemic potential. Assessing pandemic risk requires a clear understanding of existing population immunity. Leveraging ... A. Rico, B. Nicks, A. Lago, N. Silva-del-Rio. Insights into Cow-Level Risk Factors for HPAI H5N1 clinical disease in Lactating Holsteins from a Single Outbreak in Colorado (US). An observational study. JDS Communications. Abstract
submitted by kickingbird at Sep, 14, 2025 from JDS Communications (via https://www.sciencedirect.com/science/article/pii/S266691022)
Highly Pathogenic Avian Influenza (HPAI) H5N1 (clade 2.3.4.4b) has spilled over into dairy cattle populations in the US. A year after the initial outbreak, many uncertainties remain about the virus's epidemiology. ... Yang S-T, Hu M-H, Fang W-X, Diao H-M, Musonye HA,. H1N1pdm09 returns: a comparative study in Anhui, China. Microbiol Spectr. 2025 Sep 8:e0221824. Abstract
submitted by kickingbird at Sep, 13, 2025 from Microbiol Spectr. 2025 Sep 8:e0221824 (via https://journals.asm.org/doi/10.1128/spectrum.02218-24)
The 2022/2023 season witnessed a rapid resurgence of H1N1pdm09 in Anhui Province, China, surpassing previous years, prompting an examination of hemagglutinin (HA) gene mutations and cross-immunity in this ... Rimi NA, Fahad MH, Clark A, Sultana R, Hossain K,. Developing a method to estimate aerosol generation during poultry slaughtering and defeathering in Bangladesh: An experimental study. Build Environ . 2025 Mar:271:10.1016/j.buildenv.20. Abstract
submitted by kickingbird at Sep, 13, 2025 from Build Environ . 2025 Mar:271:10.1016/j.buildenv.20 (via https://www.sciencedirect.com/science/article/abs/pii/S03601)
Influenza viruses can be aerosolized when slaughtering infected chickens, which increases the risk of zoonotic transmission. We conducted pilot experiments to measure the concentrations of airborne particles ... Kawano K, Hoshino T, Yano Y, Matsuzaki K. Steady dimer formation by the S31N mutant of influenza A virus M2 protein in living cell membranes. Biochim Biophys Acta Biomembr. 2025 Sep 9:184456. Abstract
submitted by kickingbird at Sep, 13, 2025 from Biochim Biophys Acta Biomembr. 2025 Sep 9:184456 (via https://www.sciencedirect.com/science/article/abs/pii/S00052)
The integral matrix protein M2 of the influenza A virus (H3N2) has been proposed to form a proton-selective channel, and is a target of the antiviral drug amantadine hydrochloride (Am). A significant increase ... Maya Sangesland et al. Functional, immunogenetic, and structural convergence in influenza immunity between humans and macaques. Sci. Transl. Med.17,eady3570(2025). Abstract
submitted by kickingbird at Sep, 13, 2025 from Sci. Transl. Med.17,eady3570(2025) (via https://www.science.org/doi/10.1126/scitranslmed.ady3570)
Human B cell immunity to the influenza hemagglutinin (HA) stem, a universal vaccine target, is often stereotyped and immunogenetically restricted, posing hurdles to study outside of humans. Here, we show ... Ruifeng Xu, Minhao Gao, Nailou Zhang, Zhenhua Wei,. [preprint]Transcontinental Spread of HPAI H5N1 from South America to Antarctica via Avian Vectors. https://doi.org/10.1101/2025.09.06.674605. Abstract
submitted by kickingbird at Sep, 12, 2025 from https://doi.org/10.1101/2025.09.06.674605 (via https://www.biorxiv.org/content/10.1101/2025.09.06.674605v1)
Our study has for the first time identified H5N1 strains (clade 2.3.4.4b, genotype B3.2) in brown skuas from the Fildes Peninsula, South Shetland Islands, Antarctica. These findings indicate that highly ... Antje Steinfurth, etc.,al. [preprint]Investigating high pathogenicity avian influenza virus incursions to remote islands: Detection of H5N1 on Gough Island in the South Atlantic Ocean. https://doi.org/10.1101/2025.09.06.674618. Abstract
submitted by kickingbird at Sep, 12, 2025 from https://doi.org/10.1101/2025.09.06.674618 (via https://www.biorxiv.org/content/10.1101/2025.09.06.674618v1)
Understanding the mechanisms underlying the emergence and spread of high pathogenicity avian influenza virus (HPAIV) is critical for tracking its global dissemination, particularly via migratory seabirds, ... Lan R, Yang J, Li J, Li H, Cao X, Tao M, Chang H,. Continuous evolution of Eurasian avian-like H1N1 swine influenza viruses with pdm/09-derived internal genes enhances pathogenicity in mice. J Virol. 2025 Sep 8:e0043025. Abstract
submitted by kickingbird at Sep, 11, 2025 from J Virol. 2025 Sep 8:e0043025 (via https://journals.asm.org/doi/10.1128/jvi.00430-25)
Swine influenza A virus (swIAV) is an important zoonotic pathogen with the potential to cause human influenza pandemics. Swine are considered "mixing vessels" for generating novel reassortant influenza ... Holly A. Coombes, etc.,al. [preprint]Infection of ratites with clade 2.3.4.4b HPAIV H5N1: Potential implications for zoonotic risk. https://doi.org/10.1101/2025.09.08.674895. Abstract
submitted by kickingbird at Sep, 11, 2025 from https://doi.org/10.1101/2025.09.08.674895 (via https://www.biorxiv.org/content/10.1101/2025.09.08.674895v1)
We detected H5N1 high pathogenicity avian influenza in captive Greater Rhea (Rhea americana). Viral genetic analysis revealed the mammalian associated PB2-E627K mutation, indicating selection of mammalian-relevant ... Zhu, Y., Sun, Y., Deng, X., Cao, P., Li, S., Yu, H. Matrix Protein 1 (M1) of Influenza A Virus: Structural and Functional Insights. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Sep, 10, 2025 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Enveloped viruses rely on matrix proteins for structural integrity and lifecycle progression. Matrix protein 1 (M1) is the most abundant structural protein of influenza A virus (IAV), playing a multifaceted ... Chloe Stenkamp-Strahm, etc.,al. [preprint]Dairy Environments with Milk Exposure are Most Likely to Have Detection of Influenza A Virus. https://doi.org/10.1101/2025.09.03.25335023. Abstract
submitted by kickingbird at Sep, 9, 2025 from https://doi.org/10.1101/2025.09.03.25335023 (via https://www.medrxiv.org/content/10.1101/2025.09.03.25335023v)
Highly pathogenic avian influenza virus of the H5N1 subtype has been infecting U.S dairy cattle and spreading among dairy farms since March 2024. H5N1 surveillance systems for dairy farms are needed, but ... Chen P-L, Yang G, Ojha C, Banoth B, Russell CJ. Modification of H1N1 Influenza Luciferase Reporter Viruses Using StopGo Translation and/or Mouse-Adapted Mutations. Viruses. 2025; 17(9):1211. Abstract
submitted by kickingbird at Sep, 8, 2025 from Viruses. 2025; 17(9):1211 (via https://www.mdpi.com/1999-4915/17/9/1211)
Reporter viruses are valuable tools for studying infections at the cellular level and in living animals. They also enable rapid, high-throughput antiviral drug screening and serological studies. We previously ... Xia Y, Yuan J, Liu T, Zhang R, Wu C, Sui N, Li L,. TRPM2 knockdown alleviated H9N2 influenza virus infected ferroptosis in mouse pulmonary microvascular endothelial cells. Vet Microbiol. 2025 Sep 1;310:110703. Abstract
submitted by kickingbird at Sep, 6, 2025 from Vet Microbiol. 2025 Sep 1;310:110703 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
H9N2 influenza virus, a prevalent influenza A virus, causes acute lung injury through mitochondrial damage associated with oxidative stress. Transient receptor potential melastatin 2 (TRPM2) is a Ca2+ ... 6469 items, 20/Page, Page[13/324][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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