An Y, Ding X, Tian Y, Zhang M, Ma Y, Wu X, Cai M,. High-throughput pseudovirus neutralisation maps the antigenic landscape of influenza A/H1N1 viruses. EBioMedicine. 2025 Dec 2;122:106047. Abstract
submitted by kickingbird at 5 hours ago from EBioMedicine. 2025 Dec 2;122:106047 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: The continuous mutations in the haemagglutinin gene in A/H1N1 influenza viruses drives antigenic drift, necessitating frequent vaccine updates. Pseudovirus systems, with their flexible HA protein ... Huddleston J, Bedford T. Timely vaccine strain selection and genomic surveillance improve evolutionary forecast accuracy of seasonal influenza A/H3N2. Elife. 2025 Dec 4;14:RP104282. Abstract
submitted by kickingbird at 5 hours ago from Elife. 2025 Dec 4;14:RP104282 (via https://elifesciences.org/articles/104282)
Evolutionary forecasting models inform seasonal influenza vaccine design by predicting which current genetic variants will dominate in the influenza season 12 months later. Forecasting models depend on ... Guan L, etc., al. Stability of Avian Influenza A(H5N1) Virus in Milk from Infected Cows and Virus-Spiked Milk. N Engl J Med . 2025 Dec 4;393(22):2271-2273. Abstract
submitted by kickingbird at 1 days ago from N Engl J Med . 2025 Dec 4;393(22):2271-2273 (via https://www.nejm.org/doi/10.1056/NEJMc2502494)
In March 2024, public health agencies in the United States reported highly pathogenic avian influenza (HPAI) virus of subtype A(H5N1) in dairy cattle, with virus detected in milk samples from symptomatic ... Kerry Goldin, Meaghan Flagg, Tessa Lutterman, etc. Contemporary highly pathogenic avian influenza (H5N1) viruses retain neurotropism in human cerebral organoids. Open Forum Infectious Diseases, ofaf730. Abstract
submitted by kickingbird at 2 days ago from Open Forum Infectious Diseases, ofaf730 (via https://academic.oup.com/ofid/advance-article/doi/10.1093/of)
BackgroundClade 2.3.4.4b highly pathogenic avian influenza (HPAI) H5N1 viruses are widely circulating in North America with unprecedented transmission into novel host species. A high incidence of neurologic ... Jaume A. Badia-Boher, Michael Schaub, etc.,al. Evaluating the demographic impacts of the highly pathogenic avian influenza panzootic. Journal of Applied Ecology. Abstract
submitted by kickingbird at 2 days ago from Journal of Applied Ecology (via https://besjournals.onlinelibrary.wiley.com/doi/10.1111/1365)
The spread of a new highly pathogenic avian influenza virus (HPAIV-H5N1) has, since 2021, triggered one of the most severe wildlife panzootic ever reported, with suspected population crashes in hundreds ... Zhang J, Cao R, Wang Y, Sun Y, Ji X, et al. Influenza virus infection reprograms cholesterol biosynthesis to facilitate virus replication by the TAK1-RORγ axis. PLOS Pathogens 21(10): e1013646. Abstract
submitted by kickingbird at 2 days ago from PLOS Pathogens 21(10): e1013646 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Infection and replication of enveloped viruses require host cells to supply substantial amounts of cellular cholesterol for processes such as binding, entry, trafficking, assembly, and budding. However, ... Junyi Wu, etc.,al. Emerging adaptation of BJ/94 lineage H9N2 viruses to waterfowl: insights into enhanced replication and immune activation in the host cells. Poultry Science. Abstract
submitted by kickingbird at 2 days ago from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
H9N2 influenza viruses have adapted to terrestrial avian hosts via prolonged circulation in domestic chicken populations across South and Southeast Asia. Recent surveys have documented an increased incidence ... Yu, T.C., Kikawa, C., Dadonaite, B. et al. Pleiotropic mutational effects on function and stability constrain the antigenic evolution of influenza haemagglutinin. Nat Ecol Evol (2025). Abstract
submitted by kickingbird at 2 days ago from Nat Ecol Evol (2025) (via https://www.nature.com/articles/s41559-025-02895-1)
The evolution of human influenza virus haemagglutinin (HA) involves simultaneous selection to acquire antigenic mutations that escape population immunity while preserving protein function and stability. ... Asaad, H.M., Hassanin, O., Saif-Edin, M. et al. The impact of innate and humoral immune mechanisms on vaccine induced protection against avian influenza H9N2 in broilers. Sci Rep 15, 43016 (2025). Abstract
submitted by kickingbird at 2 days ago from Sci Rep 15, 43016 (2025) (via https://www.nature.com/articles/s41598-025-28122-2)
Avian influenza virus (AIV) (H9N2) is a highly contagious avian respiratory disease that causes significant economic losses in the poultry industry sector. Although immunological responses to AIV (H9N2) ... Hayes, S., Hilton, J., Mould-Quevedo, J. et al. Ecology and environment predict spatially stratified risk of H5 highly pathogenic avian influenza clade 2.3.4.4b in wild birds across Europe. Sci Rep (2025). Abstract
submitted by kickingbird at 2 days ago from Sci Rep (2025) (via https://www.nature.com/articles/s41598-025-30651-9)
Highly pathogenic avian influenza (HPAI) represents a threat to animal and human health, with the ongoing H5N1 outbreak within the H5 2.3.4.4b clade being one of the largest on record. However, it remains ... Wang, P., Fu, J., Wu, H. et al. Isolation and characterization of a novel reassortant H3N8 avian influenza virus from chickens in Eastern China. Virus Genes. 2025 Dec 1. Abstract
submitted by kickingbird at 2 days ago from Virus Genes. 2025 Dec 1 (via https://link.springer.com/article/10.1007/s11262-025-02200-z)
The H3 avian influenza virus (AIV) is a common avian pathogen, widely prevalent among domestic poultry and wild birds. In China, H3N8 AIVs led to two confirmed cases of human infection in 2022, followed ... Wang, J., Chen, P., Liu, Q. et al. Adaptive mutations in HA of avian H9N2 influenza viruses facilitate their transmission to swine. Vet Res (2025). Abstract
submitted by kickingbird at 2 days ago from Vet Res (2025) (via https://link.springer.com/article/10.1186/s13567-025-01678-7)
The cross-species transmission of avian H9N2 influenza viruses to swine increases the risk of viral adaptation to mammalian hosts. However, the mechanisms by which these H9 viruses can overcome the barriers ... Zhang W, Cowling BJ, Tam JSL, Abraham T, Chen H, D. Research Priorities for Zoonotic and Pandemic Influenza Vaccines: Evidence and Recommendations from the WHO Public Health Research Agenda for Influenza (2024 Update). Vaccines. 2025; 13(12):1206. Abstract
submitted by kickingbird at 4 days ago from Vaccines. 2025; 13(12):1206 (via https://www.mdpi.com/2076-393X/13/12/1206)
Zoonotic influenza viruses, including highly pathogenic avian influenza and swine-origin variants, continue to cause sporadic human infections with, in some cases, high case fatality rates and potential ... Baker PH, Glendenning LM, Oliveira MXS, Cobb BA, E. Distribution of sialic acids in the bovine mammary gland across different physiological states. J Dairy Sci. 2025 Nov 27:S0022-0302(25)00977-4. Abstract
submitted by kickingbird at 4 days ago from J Dairy Sci. 2025 Nov 27:S0022-0302(25)00977-4 (via https://www.journalofdairyscience.org/article/S0022-0302(25))
Highly pathogenic avian influenza (HPAI) A(H5N1) virus emerged in lactating dairy cattle in March 2024, causing mastitis-related disease and infections in other farm animals and workers. Recent work identified ... Dylan Andrieux, etc.,al. [preprint]Detection and isolation of H5N1 clade 2.3.4.4b high pathogenicity avian influenza virus from ticks (Ornithodoros maritimus) recovered from a naturally infected slender-billed gull (Chroicoce. https://doi.org/10.1101/2025.11.28.689408. Abstract
submitted by kickingbird at 5 days ago from https://doi.org/10.1101/2025.11.28.689408 (via https://www.biorxiv.org/content/10.1101/2025.11.28.689408v1)
Laridae birds, such as gulls, are known reservoirs of H13 and H16 low pathogenic avian influenza subtypes. However, during the recent outbreaks linked to the reemergence of high pathogenicity avian influenza ... Rahul K. Nelli, etc.,al. Exploring influenza A virus receptor distribution in the lactating mammary gland of domesticated livestock and in human breast tissue. Journal of Dairy Science. Abstract
submitted by kickingbird at 5 days ago from Journal of Dairy Science (via https://www.sciencedirect.com/science/article/pii/S002203022)
The spread of the highly pathogenic avian influenza (HPAI) H5N1 virus in dairy cattle, particularly affecting the mammary glands, highlights the adaptability of influenza A viruses (IAV) to infect nontraditional ... David C. Brice, etc.,al. Immunogenicity and efficacy of commercial poultry avian influenza vaccines against HPAI A(H5N1) clade 2.3.4.4b viruses in Mexico. Virology. Abstract
submitted by kickingbird at 5 days ago from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
The high-pathogenicity avian influenza A(H5N1) viruses of clade 2.3.4.4b have been detected in domestic poultry and wild birds in Mexico. Vaccination with H5 vaccines has been implemented as a complementary ... Nayduch, D., Scroggs, S.L., Shults, P. et al. Detection of H5N1 highly pathogenic avian influenza virus RNA in filth flies collected from California farms in 2024. Sci Rep (2025). Abstract
submitted by kickingbird at 6 days ago from Sci Rep (2025) (via https://www.nature.com/articles/s41598-025-29856-9)
The emergence of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b in U.S. dairy cattle highlights the urgent need to understand transmission dynamics within and among farms. House flies (Musca ... Zhang M, Qin L, Li Z, Chen J, Tong J, Ding X, Li H. Dominant substitutions underlying the antigenic evolution of H5 influenza virus. Nat Commun. 2025 Nov 28;16(1):10708. Abstract
submitted by kickingbird at 6 days ago from Nat Commun. 2025 Nov 28;16(1):10708 (via https://www.nature.com/articles/s41467-025-65730-y)
Highly pathogenic avian influenza (HPAI) H5 viruses have recently been documented in mammals including humans, posing a major threat to global public health. To prevent a potential H5 pandemic, it is critical ... Huang A, Liu Y, Li Y, Yin Z, Huo S, Wang J, Yang Z. Recombinant expression and functional characterization of influenza A virus neuraminidase in a mammalian cell system. Front Microbiol. 2025 Nov 12;16:1729393. Abstract
submitted by kickingbird at 6 days ago from Front Microbiol. 2025 Nov 12;16:1729393 (via https://www.frontiersin.org/journals/microbiology/articles/1)
The soluble and functional expression of influenza A virus neuraminidase (NA) remains a major challenge due to its membrane-associated nature and structural complexity. In this study, we established a ... 6469 items, 20/Page, Page[1/324][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
Related Pages:
Browse by Category
Learn about the flu news, articles, events and more
Subscribe to the weekly F.I.C newsletter!
|
- 
