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2024-4-28 12:47:10
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Siru Lin, Junhong Chen, etc.,al. Evolutionary dynamics and comparative pathogenicity of clade 2.3.4.4b H5 subtype avian influenza viruses, China, 2021~2022. Virologica Sinica.  Abstract  
submitted by kickingbird at 4 hours ago from Virologica Sinica (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
The recent concurrent emergence of H5N1, H5N6, and H5N8 avian influenza viruses (AIVs) has caused significant avian mortality globally. Since 2020, frequent human-animal interactions have been documented. ...

Zhi, Y.; Zhao, X.; Liu, Z.; Shen, G.; Zhang, T.; Z. Oxymatrine Modulation of TLR3 Signaling: A Dual-Action Mechanism for H9N2 Avian Influenza Virus Defense and Immune Regulation. Molecules 2024, 29, 1945.  Abstract  
submitted by kickingbird at 15 hours ago from Molecules 2024, 29, 1945 (via https://www.mdpi.com/1420-3049/29/9/1945)
In our research, we explored a natural substance called Oxymatrine, found in a traditional Chinese medicinal plant, to fight against a common bird flu virus known as H9N2. This virus not only affects birds ...

Xia, C.; Wang, T.; Hahm, B. Triggering Degradation of Host Cellular Proteins for Robust Propagation of Influenza Viruses. Int. J. Mol. Sci. 2024, 25, 4677.  Abstract  
submitted by kickingbird at 15 hours ago from Int. J. Mol. Sci. 2024, 25, 4677 (via https://www.mdpi.com/1422-0067/25/9/4677)
Following infection, influenza viruses strive to establish a new host cellular environment optimized for efficient viral replication and propagation. Influenza viruses use or hijack numerous host factors ...

Dias AS, Baker ALV, Baker RB, Zhang J, Zeller MA,. Detection and Characterization of Influenza A Virus Endemic Circulation in Suckling and Nursery Pigs Originating from Vaccinated Farms in the Same Production System. Viruses. 2024 Apr 18;16(4):626.  Abstract  
submitted by kickingbird at 15 hours ago from Viruses. 2024 Apr 18;16(4):626 (via https://www.mdpi.com/1999-4915/16/4/626)
Inactivated influenza A virus (IAV) vaccines help reduce clinical disease in suckling piglets, although endemic infections still exist. The objective of this study was to evaluate the detection of IAV ...

Tare DS, Keng SS, Walimbe AM, Pawar SD. Phylogeography and gene pool analysis of highly pathogenic avian influenza H5N1 viruses reported in India from 2006 to 2021. Arch Virol. 2024 Apr 25;169(5):111.  Abstract  
submitted by kickingbird at 2 days ago from Arch Virol. 2024 Apr 25;169(5):111 (via https://link.springer.com/article/10.1007/s00705-024-06032-4)
India has reported highly pathogenic avian influenza (HPAI) H5N1 virus outbreaks since 2006, with the first human case reported in 2021. These included viruses belonging to the clades 2.2, 2.2.2, 2.2.2.1, ...

Lihong Huang,Zhibei Jiang,Yixiang Wu,Zhaohui Yuan. Analysis of a diffusive epidemic model with a zero-infection zone. Journal of Mathematical Analysis and Applications.  Abstract  
submitted by kickingbird at 2 days ago from Journal of Mathematical Analysis and Applications (via https://www.sciencedirect.com/science/article/abs/pii/S00222)
In this paper, we propose and analyze a diffusive epidemic model with a zero-infection zone for the susceptible population. A distinct feature of the model is that the infected people are assumed to not ...

W Guo, J Luo, S Zhao, L Li, W Xing, R Gao. The critical role of RAGE in severe influenza infection: A target for control of inflammatory response in the disease. Clinical Immunology Volume 262, May 2024, 110178.  Abstract  
submitted by kickingbird at 2 days ago from Clinical Immunology Volume 262, May 2024, 110178 (via https://www.sciencedirect.com/science/article/abs/pii/S15216)
Controlling the excessive inflammatory response is one of the key ways to reduce the severity and mortality of severe influenza virus infections. RAGE is involved in inflammatory responses and acute lung ...

El-Shesheny, R., Franks, J., Kandeil, A. et al. Cross-species spill-over potential of the H9N2 bat influenza A virus. Nat Commun 15, 3449 (2024).  Abstract  
submitted by kickingbird at 3 days ago from Nat Commun 15, 3449 (2024) (via https://www.nature.com/articles/s41467-024-47635-4)
In 2017, a novel influenza A virus (IAV) was isolated from an Egyptian fruit bat. In contrast to other bat influenza viruses, the virus was related to avian A(H9N2) viruses and was probably the result ...

Halwe, N.J., Hamberger, L., Sehl-Ewert, J. et al. Bat-borne H9N2 influenza virus evades MxA restriction and exhibits efficient replication and transmission in ferrets. Nat Commun 15, 3450 (2024).  Abstract  
submitted by kickingbird at 3 days ago from Nat Commun 15, 3450 (2024) (via https://www.nature.com/articles/s41467-024-47455-6)
Influenza A viruses (IAVs) of subtype H9N2 have reached an endemic stage in poultry farms in the Middle East and Asia. As a result, human infections with avian H9N2 viruses have been increasingly reported. ...

Sandhu S, Ferrante C, MacCosham A, Atchessi N, Ban. Epidemiological characteristics of human infections with avian influenza A(H5N6) virus, China and Laos: A multiple case descriptive analysis, February 2014-June 2023. Can Commun Dis Rep. 2024 Jan 1;50(1-2):77-85.  Abstract  
submitted by kickingbird at 3 days ago from Can Commun Dis Rep. 2024 Jan 1;50(1-2):77-85 (via https://www.canada.ca/content/dam/phac-aspc/documents/servic)
Background: The first human infection with highly pathogenic avian influenza A(H5N6) virus was reported in 2014. From then until June 30, 2023, 85 human cases with confirmed A(H5N6) infection have been ...

Feoktistova, S.; Sayganova, M.; Trutneva, K.; Glaz. Abundant Intra-Subtype Reassortment Revealed in H13N8 Influenza Viruses. Viruses 2024, 16, 568.  Abstract  
submitted by kickingbird at 5 days ago from Viruses 2024, 16, 568 (via https://www.mdpi.com/1999-4915/16/4/568)
Influenza A viruses (IAVs) pose a serious threat to global health. On the one hand, these viruses cause seasonal flu outbreaks in humans. On the other hand, they are a zoonotic infection that has the potential ...

Beniston E, Skittrall JP. Locations and structures of influenza A virus packaging-associated signals and other functional elements via an in silico pipeline for predicting constrained features in RNA viruses. PLoS Comput Biol. 2024 Apr 22;20(4):e1012009.  Abstract  
submitted by kickingbird at 5 days ago from PLoS Comput Biol. 2024 Apr 22;20(4):e1012009 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Influenza A virus contains regions of its segmented genome associated with ability to package the segments into virions, but many such regions are poorly characterised. We provide detailed predictions ...

Azeem, S.; Baroch, J.; Tewari, D.; Pabilonia, K.L.. Molecular Characterization of Non-H5 and Non-H7 Avian Influenza Viruses from Non-Mallard Migratory Waterbirds of the North American Flyways, 2006~2011. Pathogens 2024, 13, 333.  Abstract  
submitted by kickingbird at 5 days ago from Pathogens 2024, 13, 333 (via https://www.mdpi.com/2076-0817/13/4/333)
The surveillance of migratory waterbirds (MWs) for avian influenza virus (AIV) is indispensable for the early detection of a potential AIV incursion into poultry. Surveying AIV infections and virus subtypes ...

Okuya K, Esaki M, Tokorozaki K, Hasegawa T, Ozawa. Isolation and genetic characterization of multiple genotypes of both H5 and H7 avian influenza viruses from environmental water in the Izumi plain, Kagoshima prefecture, Japan during the 2021/22 winte. Comp Immunol Microbiol Infect Dis. 2024 Apr 15;109.  Abstract  
submitted by kickingbird at 7 days ago from Comp Immunol Microbiol Infect Dis. 2024 Apr 15;109 (via https://www.sciencedirect.com/science/article/abs/pii/S01479)
In the 2021/22 winter, one H5N1 and nine H5N8 high pathogenicity avian influenza viruses (HPAIVs) of clade 2.3.3.4b were isolated from the water in crane roosts on the Izumi plain, Japan. Additionally, ...

Umar S, Kim S, Gao D, Chen P. Evidence of Reverse Zoonotic Transmission of Human Seasonal Influenza A Virus (H1N1, H3N2) Among Cats. Influenza Other Respir Viruses. 2024 Apr;18(4):e13.  Abstract  
submitted by kickingbird at 8 days ago from Influenza Other Respir Viruses. 2024 Apr;18(4):e13 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13296)
Human–animal interactions are closely intertwined. The connection between animal, human, and environmental health is becoming increasingly complicated with globalization, industrialization, and climate ...

Liu Y, Chen Y, Yang Z, Lin Y, Fu S, Chen J, Xu L,. Evolution and Antigenic Differentiation of Avian Influenza A(H7N9) Virus, China. Emerg Infect Dis. 2024 Apr 19;30(6).  Abstract  
submitted by kickingbird at 8 days ago from Emerg Infect Dis. 2024 Apr 19;30(6) (via https://pubmed.ncbi.nlm.nih.gov/38640498/)
We characterized the evolution and molecular characteristics of avian influenza A(H7N9) viruses isolated in China during 2021-2023. We systematically analyzed the 10-year evolution of the hemagglutinin ...

Hou Y, Deng G, Cui P, Zeng X, Li B, Wang D, He X,. Evolution of H7N9 highly pathogenic avian influenza virus in the context of vaccination. Emerg Microbes Infect. 2024 Apr 17:2343912.  Abstract  
submitted by kickingbird at 9 days ago from Emerg Microbes Infect. 2024 Apr 17:2343912 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Human infections with the H7N9 influenza virus have been eliminated in China through vaccination of poultry; however, the H7N9 virus has not yet been eradicated from poultry. Carefully analysis of H7N9 ...

VanInsberghe D, McBride DS, DaSilva J, Stark TJ, L. Genetic drift and purifying selection shape within-host influenza A virus populations during natural swine infections. PLoS Pathog. 2024 Apr 16;20(4):e1012131.  Abstract  
submitted by kickingbird at 11 days ago from PLoS Pathog. 2024 Apr 16;20(4):e1012131 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Patterns of within-host influenza A virus (IAV) diversity and evolution have been described in natural human infections, but these patterns remain poorly characterized in non-human hosts. Elucidating these ...

Liqi Liu, etc.,al. Comparison of the growth characteristics of influenza subtype H10 reassortant viruses in different cells. DOI: 10.3760/cma.j.issn.1003-9279.2016.01.020.  Abstract  
submitted by kickingbird at 15 days ago from DOI: 10.3760/cma.j.issn.1003-9279.2016.01.020 (via https://rs.yiigle.com/cmaid/867120)
Objective: To evaluate the cells for producing vaccine of avian influenza H10 subtype, the growth characteristics of influenza H10 subtype reassortant viruses in different cells (MDCK and Vero) were investigated.Methods: ...

Hu Y, Liu X, Li S, Guo X, Yang Y, Jin M. Complete genome sequence of a novel H4N1 influenza virus isolated from a pig in central China. J Virol. 2012 Dec;86(24):13879.  Abstract  
submitted by kickingbird at 15 days ago from J Virol. 2012 Dec;86(24):13879 (via https://journals.asm.org/doi/10.1128/jvi.02726-12)
Pigs are proposed to be "mixing vessel" hosts that can produce genetically novel reassortant viruses with pandemic potential. The appearance of any novel influenza viruses among pigs should pose concerns ...

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