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2026-6-24 7:35:26
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Sopko J, Han AR, Powers J, Sauer JA, Avunoori M, Z. Multimodal Data Approaches for Examining the 2024-2025 Highly Pathogenic Avian Influenza Outbreak in the United States: Descriptive Study. JMIR Public Health Surveill. 2026 Jun 22;12:e86209.  Abstract  
submitted by kickingbird at 23 hours ago from JMIR Public Health Surveill. 2026 Jun 22;12:e86209 (via https://publichealth.jmir.org/2026/1/e86209)
Background: Highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b, a globally predominant strain, was introduced into poultry in the United States in 2022 via spillover from wild birds, and has ...

Akin E, Villafuerte DA, Werner AP, Pinsley M, Pier. Emergence of an antigenically drifted and reassorted influenza B virus at the end of the 2024-25 influenza season. mBio 0:e01198-26.  Abstract  
submitted by kickingbird at 23 hours ago from mBio 0:e01198-26 (via https://journals.asm.org/doi/10.1128/mbio.01198-26)
Influenza B virus (IBV) is a significant contributor to annual and severe cases of influenza, particularly in the young and elderly. Late in the 2024-25 Northern Hemisphere influenza season, a surge of ...

Dongah Kim, etc.,al. [preprint]Local Influenza Forecasts Outperform State-Level Forecasts in the United States. https://doi.org/10.64898/2026.06.04.26354836.  Abstract  
submitted by kickingbird at 23 hours ago from https://doi.org/10.64898/2026.06.04.26354836 (via https://www.medrxiv.org/content/10.64898/2026.06.04.26354836)
Accurate outbreak forecasts are critical for timely and effective public health response. In the United States, however, most forecasts are produced at the state level, which can mask substantial sub-state ...

Baumberger, C., F. Di Pillo, F. Sanchez, et al. Serological and Molecular Surveillance of Influenza A Virus in Dogs and Cats in Central Chile. Zoonoses and Public Health.  Abstract  
submitted by kickingbird at 1 days ago from Zoonoses and Public Health (via https://onlinelibrary.wiley.com/doi/10.1111/zph.70073)
IntroductionInfluenza A virus (IAV) is a zoonotic pathogen with pandemic potential that infects a wide range of species, including companion animals. Although surveillance efforts have primarily focused ...

WPRO. Avian Influenza Weekly Update # 1049: 19 June 2026. WHO.  Abstract  
submitted by kickingbird at 2 days ago from WHO (via https://www.who.int/westernpacific/publications/m/item/avian)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ...

Jiachen Liu, etc.,al. Engineered Bacillus subtilis to deliver dsRNA via extracellular vesicles against the H9N2 avian influenza virus. Trends in Biotechnology, 2026.  Abstract  
submitted by kickingbird at 2 days ago from Trends in Biotechnology, 2026 (via https://www.cell.com/trends/biotechnology/fulltext/S0167-779)
RNA interference (RNAi) is a potent antiviral approach, outperforming traditional pesticides and broad-spectrum drugs. Its use in animal disease control faces two challenges: inefficient target design ...

Hammed Olawale Fatoyinbo, Hoyeon Jeong. [preprint]Spatiotemporal dynamics and ecological risk factors of highly pathogenic avian influenza A(H5N1) in Canadian wildlife: A One Health surveillance analysis. https://doi.org/10.48550/arXiv.2605.22352.  Abstract  
submitted by kickingbird at 2 days ago from https://doi.org/10.48550/arXiv.2605.22352 (via https://arxiv.org/html/2605.22352v1)
Highly pathogenic avian influenza A(H5N1) has expanded geographically and ecologically, affecting wild birds, mammalian wildlife, domestic animals, and humans. Wildlife surveillance provides critical early ...

Gao X, Yu H, Zhang N, Liu L, Tong J, Qi X, Huang H. Epidemiological and Virological Characteristics of H9N2 Avian Influenza Virus in Jiangsu Province, China, 2024. Viruses. 2026; 18(6):687.  Abstract  
submitted by kickingbird at 3 days ago from Viruses. 2026; 18(6):687 (via https://www.mdpi.com/1999-4915/18/6/687)
H9N2 avian influenza viruses inherently carry cross-species transmission potential, making continuous surveillance critical for pandemic prevention. This study focused on monitoring the 2024 H9N2 epidemic ...

Cole C, Cleven T, Henige M, Poulsen K, Maroney M,. Innate Pathway Selection Modulates Antibody and T-Cell Responses to Mosaic Influenza Nucleoprotein in Cattle. Viruses. 2026; 18(6):670.  Abstract  
submitted by kickingbird at 4 days ago from Viruses. 2026; 18(6):670 (via https://www.mdpi.com/1999-4915/18/6/670)
Highly pathogenic avian influenza (HPAI) is a lethal disease of poultry that has recently spilled over into mammals, including dairy cattle and humans, heightening concerns for livestock health, food security, ...

Hedman HD. Game Over for the Baseline: Influenza Hospitalization Patterns Before, During, and After the COVID-19 Pandemic (FluSurv-NET, 2009–2025). Infectious Disease Reports. 2026; 18(3):61.  Abstract  
submitted by kickingbird at 4 days ago from Infectious Disease Reports. 2026; 18(3):61 (via https://www.mdpi.com/2036-7449/18/3/61)
Background/Objectives: The trajectory of influenza hospitalization burden from pre-COVID-19 pandemic baseline through post-pandemic recovery remains poorly characterized at the national level. This study ...

Rongbao Gao. Immunity to Influenza Viruses and Vaccines: From Broader Immunity to Chrono-Optimization and Safety. Vaccines 2026, 14(6), 527.  Abstract  
submitted by kickingbird at 4 days ago from Vaccines 2026, 14(6), 527 (via https://www.mdpi.com/2076-393X/14/6/527)
Influenza viruses remain a formidable challenge to global public health, causing annual epidemics and intermittent pandemics, and resulting in over 3 million severe infections with 290,000–650,000 deaths ...

Antoine Gerodez, etc.,al. Toward Predicting Pandemic Potential: A Comparative Analysis of Virus-Host Interactions Between Diverse Influenza A Viruses and the Human Innate Immune System. PROTEOMICS.  Abstract  
submitted by kickingbird at 4 days ago from PROTEOMICS (via https://analyticalsciencejournals.onlinelibrary.wiley.com/do)
Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range ...

Carrie Julia Moore, Kira Zachmann, Susanne Lackner. Wastewater genomic surveillance of influenza A and B reveals seasonal and off-season circulation differences between municipal sites and an international airport, Germany, 2024. Water Research.  Abstract  
submitted by kickingbird at 4 days ago from Water Research (via https://www.sciencedirect.com/science/article/abs/pii/S00431)
Wastewater surveillance has proved to be a valuable tool for monitoring human pathogens. Whole-genome sequencing of SARS-CoV-2 in wastewater has been extensively applied, allowing for early detection of ...

Jolene Giacinti, etc.,al. North American perspective on the highly pathogenic avian influenza H5Nx clade 2.3.4.4b outbreak (November 2021–March 2025). Canadian Journal of Microbiology.  Abstract  
submitted by kickingbird at 4 days ago from Canadian Journal of Microbiology (via https://www.sciencedirect.com/org/science/article/pii/S00084)
Influenza A (H5Nx) highly pathogenic avian influenza viruses of clade 2.3.4.4b were first detected in North America in late 2021, initiating a multi-year outbreak unprecedented in geographic extent, duration, ...

Puduo Zhu, etc.,al. Characterization and Pathogenicity of a Novel Triple-Reassortant H6N6 Avian Influenza Virus Associated with Reproductive Failure in Breeding Ducks. Poultry Science.  Abstract  
submitted by kickingbird at 4 days ago from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
H6N6 avian influenza virus (AIV) has emerged as a predominant subtype in recent years, with frequent isolations reported in China, Vietnam, and South Korea. As critical reservoirs, waterfowl play a pivotal ...

Wei, D., Pan, Y., Zhang, X. et al. A bivalent mRNA–LNP vaccine confers broad-spectrum protection against both homologous and heterologous H5/H7 highly pathogenic avian influenza viruses in SPF chickens. Vet Res 57, 111 (2026).  Abstract  
submitted by kickingbird at 4 days ago from Vet Res 57, 111 (2026) (via https://link.springer.com/article/10.1186/s13567-026-01790-2)
The continuous evolution and co-circulation of H5 and H7 subtype highly pathogenic avian influenza viruses (HPAIVs) have caused substantial economic losses to the global poultry industry and pose a persistent ...

Peng, C., Zhang, C. & Jiang, T. Validation of a Qualitative Detection Method for Influenza A Virus RNA Based on the RT-RPA-CRISPR/Cas13a System. Curr Microbiol 83, 437 (2026).  Abstract  
submitted by kickingbird at 4 days ago from Curr Microbiol 83, 437 (2026) (via https://link.springer.com/article/10.1007/s00284-026-05028-4)
Seasonal influenza A virus (IAV) frequently causes outbreaks, creating an urgent need for rapid, cost-effective detection. Existing methods have limitations: antigen tests lack sensitivity, RT-qPCR (the ...

Jin, X., Han, P., Wang, Y. et al. Hemagglutinin double-mutation enhances binding of human-infecting avian influenza virus clade 2.3.4.4b H5Ny to human and SLeX receptors. EMBO Rep (2026).  Abstract  
submitted by kickingbird at 4 days ago from EMBO Rep (2026) (via https://link.springer.com/article/10.1038/s44319-026-00816-2)
Clade 2.3.4.4b H5Ny highly pathogenic avian influenza viruses (HPAIVs) continue to circulate worldwide, posing zoonotic threats, especially with recent cattle outbreaks. The mechanisms by which these viruses ...

Srinivas S, Chothe SK, Ramasamy S, Misra S, Nallip. Receptor basis of unusual tissue tropism of avian influenza H5N1 clade 2.3.4.4b virus in cattle. Sci Adv. 2026 Jun 19;12(25):eaea2068.  Abstract  
submitted by kickingbird at 4 days ago from Sci Adv. 2026 Jun 19;12(25):eaea2068 (via https://www.science.org/doi/10.1126/sciadv.aea2068)
The unusual tropism of H5N1 clade 2.3.4.4b for cattle mammary glands, causing necrotizing mastitis without major respiratory involvement, raises critical questions about its underlying mechanisms. We conducted ...

Ao Z, Vendramelli R, Buyu M, Truong T, Liu D, Gao. A VSV-vector vaccine simultaneously targeting H5N1 hemagglutinin and matrix protein 2 induces robust neutralizing and ADCC antibody responses and provides full protection against lethal H5N1 infection. J Virol 0:e00097-26.  Abstract  
submitted by kickingbird at 6 days ago from J Virol 0:e00097-26 (via https://journals.asm.org/doi/10.1128/jvi.00097-26)
Avian influenza A viruses, especially highly pathogenic avian influenza (HPAI) viruses, pose a significant public health threat, and a multivalent vaccine is the primary prophylactic measure to control ...

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