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2018-7-21 21:00:17
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Sant S, etc.,al. Single-Cell Approach to Influenza-Specific CD8+ T Cell Receptor Repertoires Across Different Age Groups, Tissues, and Following Influenza Virus Infection. Front Immunol. 2018 Jun 27;9:1453.  Abstract  
submitted by kickingbird at 5 days ago from Front Immunol. 2018 Jun 27;9:1453 (via https://www.ncbi.nlm.nih.gov/pubmed/29997621)
CD8+ T cells recognizing antigenic peptides derived from conserved internal viral proteins confer broad protection against distinct influenza viruses. As memory CD8+ T cells change throughout the human ...

Kuchar E, etc.,al. Knowledge Regarding Influenza and Influenza Vaccination in General Population: Results of a National Survey in Poland. Adv Exp Med Biol. 2018 Jul 12..  Abstract  
submitted by kickingbird at 5 days ago from Adv Exp Med Biol. 2018 Jul 12. (via https://www.ncbi.nlm.nih.gov/pubmed/29995213)
For the past 10 years, influenza vaccination coverage rate in Poland remains at a low 3% threshold. This low rate may be related to the unsatisfactory knowledge of vaccination, influenza, and misperception ...

de Lusignan S, etc.,al. Enhanced Safety Surveillance of Seasonal Quadrivalent Influenza Vaccines in English Primary Care: Interim Analysis. Adv Ther. 2018 Jul 11..  Abstract  
submitted by kickingbird at 5 days ago from Adv Ther. 2018 Jul 11. (via https://www.ncbi.nlm.nih.gov/pubmed/29995300)
INTRODUCTION: The European Medicines Agency (EMA) requires vaccine manufacturers to conduct enhanced safety surveillance (ESS) of seasonal influenza vaccines including a near real-time evaluation of collected ...

Ye C, etc.,al. Low coverage rate and awareness of influenza vaccine among older people in Shanghai, China: a cross-sectional study. Hum Vaccin Immunother. 2018 Jul 11:1-26.  Abstract  
submitted by kickingbird at 5 days ago from Hum Vaccin Immunother. 2018 Jul 11:1-26 (via https://www.ncbi.nlm.nih.gov/pubmed/29995561)
BACKGROUND: Older individuals are at high risk for morbidity and mortality due to influenza, and the most effective way to prevent influenza is yearly vaccination. In China, the influenza vaccine is not ...

Tsai CP, Tsai HJ. Influenza B Viruses in Pigs, Taiwan. Influenza Other Respir Viruses. 2018 Jul 11.  Abstract  
submitted by kickingbird at 5 days ago from Influenza Other Respir Viruses. 2018 Jul 11 (via https://www.ncbi.nlm.nih.gov/pubmed/29996007)
BACKGROUND: Influenza B viruses (IBVs) have never been isolated from natural-infected pigs in clinical cases, although the susceptibility of domestic pigs to experimental IBV infections had been confirmed ...

Yu WQ, etc.,al. Analysis of 15 cases of avian influenza virus (H7N9) infection. Zhonghua Jie He He Hu Xi Za Zhi. 2018 Jul 12;41(7).  Abstract  
submitted by kickingbird at 5 days ago from Zhonghua Jie He He Hu Xi Za Zhi. 2018 Jul 12;41(7) (via https://www.ncbi.nlm.nih.gov/pubmed/29996349)
Objective: To describe the clinical, chest imaging, pathological manifestations and therapeutic experience of human infection with A/H7N9 virus. Methods: The features of 15 laboratory-confirmed cases of ...

Ng YP, Yip TF, Peiris JSM, Ip NY, Lee SMY. Avian influenza A H7N9 virus infects human astrocytes and neuronal cells and induces inflammatory immune responses. J Neurovirol. 2018 Jul 9.  Abstract  
submitted by kickingbird at 5 days ago from J Neurovirol. 2018 Jul 9 (via https://www.ncbi.nlm.nih.gov/pubmed/29987581)
Seasonal, pandemic, and avian influenza virus infections may be associated with central nervous system pathology, albeit with varying frequency and different mechanisms. Here, we demonstrate that differentiated ...

Adlhoch C, Dabrera G, Penttinen P, Pebody R; Count. Protective Measures for Humans against Avian Influenza A(H5N8) Outbreaks in 22 European Union/European Economic Area Countries and Israel, 2016-17. Emerg Infect Dis. 2018 Oct 17;24(10)..  Abstract  
submitted by kickingbird at 5 days ago from Emerg Infect Dis. 2018 Oct 17;24(10). (via https://www.ncbi.nlm.nih.gov/pubmed/29989531)
We sought to better understand national approaches for managing potential human health risks during outbreaks of infection with avian influenza A(H5N8) virus during 2017-17. Twenty-three countries in the ...

Seiler P, etc.,al. H9N2 influenza viruses from Bangladesh: transmission in chicken and New World quail. Influenza Other Respir Viruses. 2018 Jul 10.  Abstract  
submitted by kickingbird at 5 days ago from Influenza Other Respir Viruses. 2018 Jul 10 (via https://www.ncbi.nlm.nih.gov/pubmed/29989679)
The H9N2 influenza viruses that have become established in Bangladeshi live poultry markets possess five gene segments of the highly pathogenic H7N3 avian influenza virus. We assessed the replication, ...

Hirotsu N, Saisho Y, Hasegawa T. The effect of neuraminidase inhibitors on household transmission in Japanese patients with influenza A and B infection: a prospective, observational study. Influenza Other Respir Viruses. 2018 Jul 10.  Abstract  
submitted by kickingbird at 5 days ago from Influenza Other Respir Viruses. 2018 Jul 10 (via https://www.ncbi.nlm.nih.gov/pubmed/29989680)
BACKGROUND: The relative ability of neuraminidase inhibitors (NAIs) to reduce household influenza transmission when given to index patients is not established.OBJECTIVES: To compare daily secondary infection ...

Schr?der T. etc.,al. The clinically approved MEK inhibitor Trametinib efficiently blocks influenza A virus propagation and cytokine expression. Antiviral Res. 2018 Jul 7;157:80-92.  Abstract  
submitted by kickingbird at 5 days ago from Antiviral Res. 2018 Jul 7;157:80-92 (via https://www.ncbi.nlm.nih.gov/pubmed/29990517)
Influenza A virus (IAV) infections are still a major global threat for humans, especially for the risk groups of young children and the elderly. Annual epidemics and sporadically occurring pandemics highlight ...

He Z, Tao H. Epidemiology and ARIMA Model of Positive-Rate of Influenza Viruses among Children in Wuhan, China: A Nine-Year Retrospective Study. Int J Infect Dis. 2018 Jul 7. pii: S1201-9712(18)3.  Abstract  
submitted by kickingbird at 5 days ago from Int J Infect Dis. 2018 Jul 7. pii: S1201-9712(18)3 (via https://www.ncbi.nlm.nih.gov/pubmed/29990540)
OBJECTIVE: Influenza is a common childhood disease and protecting children by predicting the positive rate of influenza virus is important as vaccines are not routinely administered in China. Our study ...

Yip JLY, etc.,al. Outbreaks of influenza-like illness in care homes in the East of England: impact of variations in neuraminidase inhibitor provision. Public Health. 2018 Jul 7;162:98-103..  Abstract  
submitted by kickingbird at 5 days ago from Public Health. 2018 Jul 7;162:98-103. (via https://www.ncbi.nlm.nih.gov/pubmed/29990618)
OBJECTIVES: To examine the differences in outcomes related to variable provision of antivirals in care home respiratory outbreaks.STUDY DESIGN: This is a retrospective observational study.METHODS: Routinely ...

Lau SY, etc.,al. tification of meteorological factors associated with human infection with avian influenza A H7N9 virus in Zhejiang Province, China. Sci Total Environ. 2018 Jul 6;644:696-709.  Abstract  
submitted by kickingbird at 5 days ago from Sci Total Environ. 2018 Jul 6;644:696-709 (via https://www.ncbi.nlm.nih.gov/pubmed/29990917)
BACKGROUND: Since the first reported human infection with an avian-origin influenza A (H7N9) virus in China in early 2013, there have been recurrent outbreaks of the virus in the country. Previous studies ...

Bangaru S, etc.,al. A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA. Nat Commun. 2018 Jul 10;9(1):2669.  Abstract  
submitted by kickingbird at 5 days ago from Nat Commun. 2018 Jul 10;9(1):2669 (via https://www.ncbi.nlm.nih.gov/pubmed/29991715)
The high rate of antigenic drift in seasonal influenza viruses necessitates frequent changes in vaccine composition. Recent seasonal H3 vaccines do not protect against swine-origin H3N2 variant (H3N2v) ...

Sean G. Young´╝îAndrew Kitchen, Ghazi Kayali´╝îMargare. Unlocking pandemic potential: prevalence and spatial patterns of key substitutions in avian influenza H5N1 in Egyptian isolates. BMC Infectious Diseases201818:314.  Abstract  
submitted by kickingbird at 12 days ago from BMC Infectious Diseases201818:314 (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
BackgroundAvian influenza H5N1 has a high human case fatality rate, but is not yet well-adapted to human hosts. Amino acid substitutions currently circulating in avian populations may enhance viral fitness ...

Gao Z, etc.,al. The PA-interacting host protein nucleolin acts as an antiviral factor during highly pathogenic H5N1 avian influenza virus infection. Arch Virol. 2018 Jul 5.  Abstract  
submitted by kickingbird at 12 days ago from Arch Virol. 2018 Jul 5 (via https://www.ncbi.nlm.nih.gov/pubmed/29974255)
Polymerase acidic (PA) protein is a multifunctional regulator of influenza A virus (IAV) replication and pathogenesis. In a previous study, we reported that nucleolin (NCL) is a novel PA-interacting host ...

Keating R, Morris MY, etc.,al. Potential killers exposed: tracking endogenous influenza-specific CD8+ T cells. Immunol Cell Biol. 2018 Jul 4..  Abstract  
submitted by kickingbird at 12 days ago from Immunol Cell Biol. 2018 Jul 4. (via https://www.ncbi.nlm.nih.gov/pubmed/29972699)
Current influenza A virus (IAV) vaccines stimulate antibody responses that are directed against variable regions of the virus, and are therefore ineffective against divergent strains. As CD8+ T cells target ...

Lawrence JL, Hindi H. Capillary Leak Syndrome Aggravated by Influenza Type A Infection. Cureus. 2018 Apr 30;10(4):e2554..  Abstract  
submitted by kickingbird at 12 days ago from Cureus. 2018 Apr 30;10(4):e2554. (via https://www.ncbi.nlm.nih.gov/pubmed/29974010)
A 41-year-old female presented to the emergency department with nausea, vomiting, and diarrhea. Five days prior to this, she tested positive for influenza type A in an urgent care clinic and received Tamiflu. ...

Jaramillo JM, Ma J, van den Driessche P, Yuan S. Host contact structure is important for the recurrence of Influenza A. J Math Biol. 2018 Jul 4.  Abstract  
submitted by kickingbird at 12 days ago from J Math Biol. 2018 Jul 4 (via https://www.ncbi.nlm.nih.gov/pubmed/29974201)
An important characteristic of influenza A is its ability to escape host immunity through antigenic drift. A novel influenza A strain that causes a pandemic confers full immunity to infected individuals. ...

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