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2024-3-1 10:12:53

Zhang M, Liu M, Chen H, Qiu T, Jin X, Fu W, Teng Q. PB2 residue 473 contributes to the mammalian virulence of H7N9 avian influenza virus by modulating viral polymerase activity via ANP32A. J Virol. 2024 Feb 29:e0194423.  Abstract  
submitted by kickingbird at 3 hours ago from J Virol. 2024 Feb 29:e0194423 (via https://journals.asm.org/doi/10.1128/jvi.01944-23)
Since the first human infection reported in 2013, H7N9 avian influenza virus (AIV) has been regarded as a serious threat to human health. In this study, we sought to identify the virulence determinant ...

Yang R, Pan M, Guo J, Huang Y, Zhang QC, Deng T, W. Mapping of the influenza A virus genome RNA structure and interactions reveals essential elements of viral replication. Cell Rep. 2024 Feb 27;43(3):113833.  Abstract  
submitted by kickingbird at 1 days ago from Cell Rep. 2024 Feb 27;43(3):113833 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(24)001)
Influenza A virus (IAV) represents a constant public health threat. The single-stranded, segmented RNA genome of IAV is replicated in host cell nuclei as a series of 8 ribonucleoprotein complexes (vRNPs) ...

Han J, Chang W, Fang J, Hou X, Li Z, Wang J, Deng. The H9N2 avian influenza virus increases APEC adhesion to oviduct epithelia by viral NS1 protein-mediated activation of the TGF-β pathway. J Virol. 2024 Feb 28:e0151223.  Abstract  
submitted by kickingbird at 1 days ago from J Virol. 2024 Feb 28:e0151223 (via https://journals.asm.org/doi/10.1128/jvi.01512-23)
Avian influenza A (H9N2) avian influenza is a low-pathogenic avian influenza circulating in poultry and wild birds worldwide and frequently contributes to chicken salpingitis that is caused by avian pathogenic ...

Cardenas-Garcia S, Cáceres CJ, Jain A, Geiger G, M. Impact of sex on humoral immunity with live influenza B virus vaccines in mice. NPJ Vaccines. 2024 Feb 26;9(1):45.  Abstract  
submitted by kickingbird at 2 days ago from NPJ Vaccines. 2024 Feb 26;9(1):45 (via https://www.nature.com/articles/s41541-024-00827-x)
Influenza B virus (FLUBV) poses a significant infectious threat, with frequent vaccine mismatch limiting its effectiveness. Our previous work investigated the safety and efficacy of modified live attenuated ...

de Bruin ACM, Spronken MI, Kok A, Rosu ME, de Meul. Species-specific emergence of H7 highly pathogenic avian influenza virus is driven by intrahost selection differences between chickens and ducks. PLoS Pathog. 2024 Feb 26;20(2):e1011942.  Abstract  
submitted by kickingbird at 3 days ago from PLoS Pathog. 2024 Feb 26;20(2):e1011942 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Highly pathogenic avian influenza viruses (HPAIVs) cause severe hemorrhagic disease in terrestrial poultry and are a threat to the poultry industry, wild life, and human health. HPAIVs arise from low pathogenic ...

Gu C, Fan S, Dahn R, Babujee L, Chiba S, Guan L, M. Characterization of a human H3N8 influenza virus. EBioMedicine. 2024 Feb 25;101:105034.  Abstract  
submitted by kickingbird at 3 days ago from EBioMedicine. 2024 Feb 25;101:105034 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: In 2022 and 2023, novel reassortant H3N8 influenza viruses infected three people, marking the first human infections with viruses of this subtype.Methods: Here, we generated one of these viruses ...

Rose AMC, Pozo F, Martínez-Baz I, Mazagatos C, Bos. Vaccine effectiveness against influenza hospitalisation in adults during the 2022/2023 mixed season of influenza A(H1N1)pdm09, A(H3N2) and B circulation, Europe: VEBIS SARI VE hospital network. Influenza Other Respir Viruses. 2024 Feb;18(2):e13.  Abstract  
submitted by kickingbird at 3 days ago from Influenza Other Respir Viruses. 2024 Feb;18(2):e13 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13255)
We conducted a multicentre hospital-based test-negative case-control study to measure vaccine effectiveness (VE) against PCR-confirmed influenza in adult patients with severe acute respiratory infection ...

Wibawa H, Wibowo PE, Supriyadi A, Lestari L, Silab. Highly Pathogenic Avian Influenza A(H5N1) Virus Clade in Domestic Ducks, Indonesia, 2022. Emerg Infect Dis. 2024 Mar;30(3):586-590.  Abstract  
submitted by kickingbird at 3 days ago from Emerg Infect Dis. 2024 Mar;30(3):586-590 (via https://wwwnc.cdc.gov/eid/article/30/3/23-0973_article)
Highly pathogenic avian influenza A(H5N1) clade viruses were isolated from domestic ducks in South Kalimantan, Indonesia, during April 2022. The viruses were genetically similar to those detected ...

Plaza PI, Gamarra-Toledo V, Euguí JR, Lambertucci. Recent Changes in Patterns of Mammal Infection with Highly Pathogenic Avian Influenza A(H5N1) Virus Worldwide. Emerg Infect Dis. 2024 Mar;30(3):444-452.  Abstract  
submitted by kickingbird at 3 days ago from Emerg Infect Dis. 2024 Mar;30(3):444-452 (via https://wwwnc.cdc.gov/eid/article/30/3/23-1098_article)
We reviewed information about mammals naturally infected by highly pathogenic avian influenza A virus subtype H5N1 during 2 periods: the current panzootic (2020-2023) and previous waves of infection (2003-2019). ...

Ranum JN, Ledwith MP, Alnaji FG, Diefenbacher M, O. Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome. Nucleic Acids Res. 2024 Feb 26:gkae133.  Abstract  
submitted by kickingbird at 3 days ago from Nucleic Acids Res. 2024 Feb 26:gkae133 (via https://academic.oup.com/nar/advance-article/doi/10.1093/nar)
Productive infections by RNA viruses require faithful replication of the entire genome. Yet many RNA viruses also produce deletion-containing viral genomes (DelVGs), aberrant replication products with ...

Yang RS, Traver M, Barefoot N, Stephens T, Alabanz. Mosaic quadrivalent influenza vaccine single nanoparticle characterization. Sci Rep. 2024 Feb 24;14(1):4534.  Abstract  
submitted by kickingbird at 4 days ago from Sci Rep. 2024 Feb 24;14(1):4534 (via https://www.nature.com/articles/s41598-024-54876-2)
Recent work by our laboratory and others indicates that co-display of multiple antigens on protein-based nanoparticles may be key to induce cross-reactive antibodies that provide broad protection against ...

Murphy C, Kwan MYW, Chan ELY, Wong JSC, Sullivan S. Influenza vaccine effectiveness against hospitalizations associated with influenza A(H3N2) in Hong Kong children aged 9 months to 17 years, June-November 2023. Vaccine. 2024 Feb 22:S0264-410X(24)00215-9.  Abstract  
submitted by kickingbird at 5 days ago from Vaccine. 2024 Feb 22:S0264-410X(24)00215-9 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
A test negative study was carried out from 13 June through to 15 November 2023 enrolling 3183 children hospitalized with acute respiratory illness in Hong Kong. Influenza A and B viruses were detected ...

Ricci I, Tofani S, Lelli D, Vincifori G, Rosone F,. First Reported Circulation of Equine Influenza H3N8 Florida Clade 1 Virus in Horses in Italy. Animals (Basel). 2024 Feb 12;14(4):598.  Abstract  
submitted by kickingbird at 5 days ago from Animals (Basel). 2024 Feb 12;14(4):598 (via https://www.mdpi.com/2076-2615/14/4/598)
Background: Equine influenza (EI) is a highly contagious viral disease of equids characterized by pyrexia and respiratory signs. Like other influenza A viruses, antigenic drift or shift could lead to a ...

Chen W, Ma T, Liu S, Zhong Y, Yu H, Shu J, Wang X,. N-Glycan Profiles of Neuraminidase from Avian Influenza Viruses. Viruses. 2024 Jan 26;16(2):190.  Abstract  
submitted by kickingbird at 5 days ago from Viruses. 2024 Jan 26;16(2):190 (via https://www.mdpi.com/1999-4915/16/2/190)
The cleavage of sialic acids by neuraminidase (NA) facilitates the spread of influenza A virus (IV) descendants. Understanding the enzymatic activity of NA aids research into the transmission of IVs. An ...

Li T, Zhao C, Guo Y, Dong J, Du F, Zhou Y, Shu S,. Genetic and Biological Characteristics of Duck-Origin H4N6 Avian Influenza Virus Isolated in China in 2022. Viruses. 2024 Jan 30;16(2):207.  Abstract  
submitted by kickingbird at 5 days ago from Viruses. 2024 Jan 30;16(2):207 (via https://www.mdpi.com/1999-4915/16/2/207)
The interaction between migratory birds and domestic waterfowl facilitates viral co-infections, leading to viral reassortment and the emergence of novel viruses. In 2022, samples were collected from duck ...

Di Pietro C, Haberman AM, Lindenbach BD, Smith PC,. Prior Influenza Infection Mitigates SARS-CoV-2 Disease in Syrian Hamsters. Viruses. 2024 Feb 3;16(2):246.  Abstract  
submitted by kickingbird at 5 days ago from Viruses. 2024 Feb 3;16(2):246 (via https://www.mdpi.com/1999-4915/16/2/246)
Seasonal infection rates of individual viruses are influenced by synergistic or inhibitory interactions between coincident viruses. Endemic patterns of SARS-CoV-2 and influenza infection overlap seasonally ...

Nagy A, Stará M, ?erníková L, Kli?ková E, Horák O,. Enzootic Circulation, Massive Gull Mortality and Poultry Outbreaks during the 2022/2023 High-Pathogenicity Avian Influenza H5N1 Season in the Czech Republic. Viruses. 2024 Jan 31;16(2):221.  Abstract  
submitted by kickingbird at 5 days ago from Viruses. 2024 Jan 31;16(2):221 (via https://www.mdpi.com/1999-4915/16/2/221)
In 2022/2023, Europe experienced its third consecutive season of high-pathogenicity avian influenza. During this period, the Czech Republic was again severely affected. For the first time, the number of ...

Flores RA, Cammayo-Fletcher PLT, Nguyen BT, Villav. Genetic Characterization and Phylogeographic Analysis of the First H13N6 Avian Influenza Virus Isolated from Vega Gull in South Korea. Viruses. 2024 Feb 12;16(2):285.  Abstract  
submitted by kickingbird at 5 days ago from Viruses. 2024 Feb 12;16(2):285 (via https://www.mdpi.com/1999-4915/16/2/285)
Avian influenza virus (AIV) is a pathogen with zoonotic and pandemic potential. Migratory birds are natural reservoirs of all known subtypes of AIVs, except for H17N10 and H18N11, and they have been implicated ...

Carter T, Iqbal M. The Influenza A Virus Replication Cycle: A Comprehensive Review. Viruses. 2024 Feb 19;16(2):316.  Abstract  
submitted by kickingbird at 5 days ago from Viruses. 2024 Feb 19;16(2):316 (via https://www.mdpi.com/1999-4915/16/2/316)
Influenza A virus (IAV) is the primary causative agent of influenza, colloquially called the flu. Each year, it infects up to a billion people, resulting in hundreds of thousands of human deaths, and causes ...

Tawfik A, Kawaguchi T, Takahashi M, Setoh K, Yamag. Transcriptomic Analysis Reveals Sixteen Potential Genes Associated with the Successful Differentiation of Antibody-Secreting Cells through the Utilization of Unfolded Protein Response Mechanisms in Ro. Vaccines (Basel). 2024 Jan 29;12(2):136.  Abstract  
submitted by kickingbird at 5 days ago from Vaccines (Basel). 2024 Jan 29;12(2):136 (via https://www.mdpi.com/2076-393X/12/2/136)
The seasonal influenza vaccine remains one of the vital recommended infection control measures for the elderly with chronic illnesses. We investigated the immunogenicity of a single dose of influenza vaccine ...

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