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2020-4-1 13:54:22
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Lee CY, An SH, Choi JG, Lee YJ, Kim JH, Kwon HJ. Rank orders of mammalian pathogenicity-related PB2 mutations of avian influenza A viruses. Sci Rep. 2020 Mar 24;10(1):5359..  Abstract  
submitted by kickingbird at 1 days ago from Sci Rep. 2020 Mar 24;10(1):5359. (via https://www.ncbi.nlm.nih.gov/pubmed/32210274)
The PB2 gene is one of the key determinants for the mammalian adaptation of avian influenza A viruses (IAVs). Although mammalian pathogenicity-related mutations (MPMs) in PB2 genes were identified in different ...

Jia N, et al. The Human Lung Glycome Reveals Novel Glycan Ligands for Influenza A Virus. Sci Rep. 2020 Mar 24;10(1):5320.  Abstract  
submitted by kickingbird at 1 days ago from Sci Rep. 2020 Mar 24;10(1):5320 (via https://www.ncbi.nlm.nih.gov/pubmed/32210305)
Glycans within human lungs are recognized by many pathogens such as influenza A virus (IAV), yet little is known about their structures. Here we present the first analysis of the N- and O- and glycosphingolipid-glycans ...

Venkatesh D, et al. Detection of H3N8 influenza A virus with multiple mammalian-adaptive mutations in a rescued Grey seal (Halichoerus grypus) pup. Virus Evol. 2020 Mar 18;6(1):veaa016..  Abstract  
submitted by kickingbird at 1 days ago from Virus Evol. 2020 Mar 18;6(1):veaa016. (via https://academic.oup.com/ve/article/6/1/veaa016/5809603)
Avian influenza A viruses (IAVs) in different species of seals display a spectrum of pathogenicity, from sub-clinical infection to mass mortality events. Here we present an investigation of avian IAV infection ...

Shi C, Shi P, Yang X, Bao J, Qian Y, Shen Y. Person-to-Person Transmission of Avian Influenza A (H7N9) Among Family Members in Eastern China, 2016. Disaster Med Public Health Prep. 2020 Mar 27:1-6.  Abstract  
submitted by kickingbird at 1 days ago from Disaster Med Public Health Prep. 2020 Mar 27:1-6 (via https://www.cambridge.org/core/journals/disaster-medicine-an)
OBJECTIVE: Human infections with avian influenza A (H7N9) virus are associated with exposure to poultry and live poultry markets, but the evidence of person-to-person transmission remains limited. This ...

Yang F, et al. Generation of neutralizing and non-neutralizing monoclonal antibodies against H7N9 influenza virus. Emerg Microbes Infect. 2020 Mar 20;9(1):664-675..  Abstract  
submitted by kickingbird at 8 days ago from Emerg Microbes Infect. 2020 Mar 20;9(1):664-675. (via https://www.ncbi.nlm.nih.gov/pubmed/32193996)
The H7N9 viruses have been circulating for six years. The insertion of a polybasic cleavage site in the haemagglutinin (HA) protein of H7N9 has resulted in the emergence of a highly pathogenic (HP) avian ...

Wu H, Liu F, Yang F, Xiao Y, Yao H, Wu N. Amino acid substitutions involved in the adaptation of a novel H7N7 avian influenza virus in mice. Res Vet Sci. 2020 Mar 10;130:203-206..  Abstract  
submitted by kickingbird at 8 days ago from Res Vet Sci. 2020 Mar 10;130:203-206. (via https://www.ncbi.nlm.nih.gov/pubmed/32200160)
The H7N7 avian influenza viruses can infect humans and poses a great threat to human health. To identify the amino acid substitutions that are associated with adaptation of avian-origin H7N7 virus to mammals, ...

Zhang T, et al. Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis. Cell. 2020 Mar 19;180(6):1115-1129.e13..  Abstract  
submitted by kickingbird at 8 days ago from Cell. 2020 Mar 19;180(6):1115-1129.e13. (via https://www.ncbi.nlm.nih.gov/pubmed/32200799)
Influenza A virus (IAV) is a lytic RNA virus that triggers receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-mediated pathways of apoptosis and mixed lineage kinase domain-like pseudokinase ...

Shiu EYC, et al. Frequent recovery of influenza A but not influenza B virus RNA in aerosols in pediatric patient rooms. Indoor Air. 2020 Mar 23..  Abstract  
submitted by kickingbird at 8 days ago from Indoor Air. 2020 Mar 23. (via https://www.ncbi.nlm.nih.gov/pubmed/32201989)
Influenza transmission occurs through the air, but the relative importance of small droplets, or aerosols, in influenza transmission especially within healthcare facilities remains uncertain. Detections ...

Balasuriya UBR. Type A Influenza Virus Detection from Horses by Real-Time RT-qPCR and Insulated Isothermal RT-PCR. Methods Mol Biol. 2020;2123:383-392.  Abstract  
submitted by kickingbird at Mar, 16, 2020 from Methods Mol Biol. 2020;2123:383-392 (via https://www.ncbi.nlm.nih.gov/pubmed/32170704)
Equine influenza (EI) is a highly contagious disease of horses caused by the equine influenza virus (EIV) H3N8 subtype. EI is the most important respiratory virus infection of horses and can disrupt major ...

Balasuriya UBR. RNA Extraction from Equine Samples for Equine Influenza Virus. Methods Mol Biol. 2020;2123:369-382.  Abstract  
submitted by kickingbird at Mar, 16, 2020 from Methods Mol Biol. 2020;2123:369-382 (via https://www.ncbi.nlm.nih.gov/pubmed/32170703)
The primary goals of this chapter are to discuss common viral RNA isolation and purification methods that are routinely used by various diagnostic laboratories and to highlight the advantages and drawbacks ...

Chambers TM, Reedy SE. Equine Influenza Culture Methods. Methods Mol Biol. 2020;2123:393-400..  Abstract  
submitted by kickingbird at Mar, 16, 2020 from Methods Mol Biol. 2020;2123:393-400. (via https://www.ncbi.nlm.nih.gov/pubmed/32170705)
Equine influenza viruses are cultured in embryonated chicken eggs or in mammalian cells, generally Madin-Darby canine kidney (MDCK) cells, using methods much the same as for other influenza A viruses. ...

Chambers TM, Reedy SE. Equine Influenza Diagnosis: Sample Collection and Transport. Methods Mol Biol. 2020;2123:361-367.  Abstract  
submitted by kickingbird at Mar, 16, 2020 from Methods Mol Biol. 2020;2123:361-367 (via https://www.ncbi.nlm.nih.gov/pubmed/32170702)
In horses, presumptive diagnosis of equine influenza is commonly made on the basis of clinical signs. This alone is insufficient for confirmation of equine influenza, because other equine infectious respiratory ...

Cho JH, et al. Molecular recognition of a host protein by NS1 of pandemic and seasonal influenza A viruses. Proc Natl Acad Sci U S A. 2020 Mar 9.  Abstract  
submitted by kickingbird at Mar, 11, 2020 from Proc Natl Acad Sci U S A. 2020 Mar 9 (via https://www.pnas.org/content/early/2020/03/06/1920582117)
The 1918 influenza A virus (IAV) caused the most severe flu pandemic in recorded human history. Nonstructural protein 1 (NS1) is an important virulence factor of the 1918 IAV. NS1 antagonizes host defense ...

Li X, Zhang L, Liu Y, Ma L, Zhang N, Xia C. Structures of the MHC-I molecule BF2*1501 disclose the preferred presentation of an H5N1 virus-derived epitope. J Biol Chem. 2020 Mar 9..  Abstract  
submitted by kickingbird at Mar, 11, 2020 from J Biol Chem. 2020 Mar 9. (via https://www.ncbi.nlm.nih.gov/pubmed/32152225)
Lethal infections by strains of the highly pathogenic avian influenza virus (HPAIV) H5N1 pose serious threats to both the poultry industry and public health worldwide. A lack of confirmed HPAIV epitopes ...

Chambers TM. Equine Influenza. Cold Spring Harb Perspect Med. 2020 Mar 9..  Abstract  
submitted by kickingbird at Mar, 11, 2020 from Cold Spring Harb Perspect Med. 2020 Mar 9. (via https://www.ncbi.nlm.nih.gov/pubmed/32152243)
Horses are the third major mammalian species, along with humans and swine, long known to be subject to acute upper respiratory disease from influenza A virus infection. The viruses responsible are subtype ...

Yang S, et al. NMP4 regulates the innate immune response to influenza A virus infection. Mucosal Immunol. 2020 Mar 9.  Abstract  
submitted by kickingbird at Mar, 11, 2020 from Mucosal Immunol. 2020 Mar 9 (via https://www.ncbi.nlm.nih.gov/pubmed/32152414)
Severe influenza A virus infection typically triggers excessive and detrimental lung inflammation with massive cell infiltration and hyper-production of cytokines and chemokines. We identified a novel ...

Coloma R, et al. Structural insights into influenza A virus ribonucleoproteins reveal a processive helical track as transcription mechanism. Nat Microbiol. 2020 Mar 9..  Abstract  
submitted by kickingbird at Mar, 11, 2020 from Nat Microbiol. 2020 Mar 9. (via https://www.nature.com/articles/s41564-020-0675-3)
The influenza virus genome consists of eight viral ribonucleoproteins (vRNPs), each consisting of a copy of the polymerase, one of the genomic RNA segments and multiple copies of the nucleoprotein arranged ...

Leite JA, et al. Genetic evolution of influenza viruses among selected countries in Latin America, 2017-2018. PLoS One. 2020 Mar 10;15(3):e0227962..  Abstract  
submitted by kickingbird at Mar, 11, 2020 from PLoS One. 2020 Mar 10;15(3):e0227962. (via https://journals.plos.org/plosone/article?id=10.1371/journal)
OBJECTIVE: Since the 2009 influenza pandemic, Latin American (LA) countries have strengthened their influenza surveillance systems. We analyzed influenza genetic sequence data from the 2017 through 2018 ...

Morris AK, et al. Cellular mRNA export factor UAP56 recognizes nucleic acid binding site of influenza virus NP protein. Biochem Biophys Res Commun. 2020 Feb 19.  Abstract  
submitted by kickingbird at Mar, 1, 2020 from Biochem Biophys Res Commun. 2020 Feb 19 (via https://www.ncbi.nlm.nih.gov/m/pubmed/32085897/)
Influenza A virus nucleoprotein (NP) is a structural component that encapsulates the viral genome into the form of ribonucleoprotein complexes (vRNPs). Efficient assembly of vRNPs is critical for the virus ...

Kumari R, et al. Influenza virus NS1- C/EBPβ gene regulatory complex inhibits RIG-I transcription. Antiviral Res. 2020 Feb 2.  Abstract  
submitted by kickingbird at Mar, 1, 2020 from Antiviral Res. 2020 Feb 2 (via https://www.ncbi.nlm.nih.gov/m/pubmed/32092305/)
Influenza virus non-structural protein 1 (NS1) counteracts host antiviral innate immune responses by inhibiting Retinoic acid inducible gene-I (RIG-I) activation. However, whether NS1 also specifically ...

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