Zheng H, Chen Y, Gao R, Yang W, Lu X, Chen Y, Gu M. NA-N322S and G389D mutations synergize with PB2-627K to enhance H7N9 pathogenicity in mammals. Vet Microbiol. 2025 Oct 30;312:11077. Abstract submitted by kickingbird at 11 hours ago from Vet Microbiol. 2025 Oct 30;312:11077 The H7N9 subtype avian influenza virus (AIV) is currently the subtype with the highest number of human infection cases, with a mortality rate of nearly 40 %,40 %, posing a serious threat to public health. ... Entriken CG, Bruce KL, Coyne BM, Kruyer SH, Sincla. Improved efficacy of an influenza DNA vaccine through high-density microarray patch delivery. J Gen Virol. 2025 Nov;106(11):002179. Abstract submitted by kickingbird at 11 hours ago from J Gen Virol. 2025 Nov;106(11):002179 Pandemic preparedness requires vaccine platforms that are fast to produce, thermostable and suitable for broad deployment. DNA vaccines are well suited to this task but have historically suffered from ... Sullivan J, Poulson R, Olsen GH, Berlin AM, Cao Z,. Rapid increase in antibodies to influenza A virus H5 and N1 in lesser scaup (Aythya Affinis) following the introduction of 2.3.4.4b H5N1 into north America. Can J Microbiol. 2025 Nov 13. Abstract submitted by kickingbird at 11 hours ago from Can J Microbiol. 2025 Nov 13 Clade 2.3.4.4b Eurasian-origin H5N1 entered North America in late 2021 and spread across the continent. While studies have characterized the antibody response mounted by dabbling ducks following exposure, ... Freja CM Kirsebom, etc.,al. [Preprint]Early influenza virus characterisation and vaccine effectiveness in England in autumn 2025. UK Health Security Agency. Abstract submitted by kickingbird at 12 hours ago from UK Health Security Agency New data published today by the UK Health Security Agency (UKHSA) shows the 2025/26 vaccine is currently 70 to 75% effective at preventing hospital attendance in children aged 2 to 17 years and 30 to 40% ... Hunter Joseph Ries, etc.,al. [preprint]Weak selection and stochastic processes limit the emergence of antigenic variants during household transmission of influenza A viruses. https://doi.org/10.1101/2025.11.04.686470. Abstract submitted by kickingbird at 1 days ago from https://doi.org/10.1101/2025.11.04.686470 Influenza viruses undergo antigenic drift, the gradual accumulation of mutations that cause antigenic changes in the viral surface proteins hemagglutinin (HA) and neuraminidase (NA). Although selection ... | |