WHO launches new global influenza strategy    
submitted by kickingbird at Mar, 12, 2019 from WHO
WHO released a Global Influenza Strategy for 2019-2030 aimed at protecting people in all countries from the threat of influenza. The goal of the strategy is to prevent seasonal influenza, control the spread ...

GISAID: H5N1 Bird Flu Circulating in Dairy Cows in the United States    
submitted by kickingbird at 21 hours ago from GISAID
The 2.3.4.4b clade of the highly pathogenic avian influenza (HPAI) virus causing outbreaks in wild and domestic birds around the world, continues to spread in dairy farms across the United States since ...

US: CDC Confirms 3rd Human Case of H5 Bird Flu in California    
submitted by kickingbird at 2 days ago from USCDC
The Centers for Disease Control and Prevention (CDC) has confirmed a third human case of H5 bird flu in California. Like the two cases in that state confirmed last week, the person reported occupational ...

GISAID: H5N1 Bird Flu Circulating in Dairy Cows in the United States    
submitted by kickingbird at 4 days ago from GISAID
The 2.3.4.4b clade of the highly pathogenic avian influenza (HPAI) virus causing outbreaks in wild and domestic birds around the world, continues to spread in dairy farms across the United States since ...

USFDA: Ongoing Work to Ensure Continued Effectiveness of the Federal-State Milk Safety System    
submitted by kickingbird at 8 days ago from USFDA
October 3, 2024Since the onset of the Highly Pathogenic Avian Influenza A H5N1 (H5N1) outbreak in dairy cattle earlier this year, researchers across the federal and state governments have been working ...

María Ríos Carrasco, Andrea Gr?ne, Judith M. A. v. The mammary glands of cows abundantly display receptors for circulating avian H5 viruses. Virology， 10 Oct 2024.  Abstract  
submitted by kickingbird at 8 hours ago from Virology， 10 Oct 2024
Influenza A viruses (IAVs) from the H5N1 2.3.4.4b clade are circulating in dairy farms in the USA.; ruminants were presumed not to be hosts for IAVs. Previously, IAV-positive mammalian species were hunters ...

Jarek Juraszek, etc.,al. Engineering a cleaved, prefusion-stabilized influenza B virus hemagglutinin by identification and locking of all six pH-switches. PNAS Nexus.  Abstract  
submitted by kickingbird at 8 hours ago from PNAS Nexus
Vaccine components based on viral fusion proteins require high stability of the native prefusion conformation for optimal potency and manufacturability. In the case of influenza B virus hemagglutinin (HA), ...

Owuor DC, Ngoi JM, Nyasimi FM, Murunga N, Nyiro JU. Local patterns of spread of influenza A H3N2 virus in coastal Kenya over a 1-year period revealed through virus sequence data. Sci Rep. 2024 Oct 8;14(1):23426.  Abstract  
submitted by kickingbird at 8 hours ago from Sci Rep. 2024 Oct 8;14(1):23426
The patterns of spread of influenza A viruses in local populations in tropical and sub-tropical regions are unclear due to sparsity of representative spatiotemporal sequence data. We sequenced and analyzed ...

Zhang K, Cagatay T, Xie D, Angelos AE, Cornelius S. Cellular NS1-BP Protein Interacts with the mRNA Export Receptor NXF1 to Mediate Nuclear Export of Influenza Virus M mRNAs. J Biol Chem. 2024 Oct 7:107871.  Abstract  
submitted by kickingbird at 9 hours ago from J Biol Chem. 2024 Oct 7:107871
Influenza A viruses have eight genomic RNAs that are transcribed in the host cell nucleus. Two of the viral mRNAs undergo alternative splicing. The M1 mRNA encodes the matrix protein 1 (M1) and is also ...

Schaub A, Luo B, David SC, Glas I, Klein LK, Costa. Salt Supersaturation as an Accelerator of Influenza A Virus Inactivation in 1 μL Droplets. Environ Sci Technol. 2024 Oct 11.  Abstract  
submitted by kickingbird at 9 hours ago from Environ Sci Technol. 2024 Oct 11
Influenza A virus (IAV) spreads through exhaled aerosol particles and larger droplets. Estimating the stability of IAV is challenging and depends on factors such as the respiratory matrix and drying kinetics. ...