Hoxie, I., Vasilev, K., Clark, J. et al. A TRAC-478-adjuvanted recombinant N1 neuraminidase influenza virus vaccine induces balanced and broadly protective immune responses. npj Vaccines (2026). Abstract
submitted by kickingbird at May, 3, 2026 from npj Vaccines (2026) (via https://link.springer.com/article/10.1038/s41541-026-01456-2)
Licensed influenza vaccines primarily target the variable hemagglutinin protein and provide inadequate cross-protection against mismatched or drifted viral strains. One promising approach to enhance the ... Ziejka RS, Brown JD, Thompson-Iritani S, Ramirez V. Human and Hunting Dog Interactions in the United States: Exploring Potential Transmission Pathways of Zoonotic Diseases and Highly Pathogenic Avian Influenza Virus. Veterinary Sciences. 2026; 13(5):449. Abstract
submitted by kickingbird at May, 2, 2026 from Veterinary Sciences. 2026; 13(5):449 (via https://www.mdpi.com/2306-7381/13/5/449)
Since 2022, numerous H5N1 highly pathogenic avian influenza virus (HPAIV) detections have been reported in wild and domestic mammals in North America. Although H5N1 HPAIV detections in dogs are rare, hunting ... Benedetti E, Artuso MC, Byrne A, Garibotto MdB, Av. Emergence and Evolution of Triple Reassortant Highly Pathogenic Avian Influenza A(H5N1) Virus, Argentina, 2025. Viruses. 2026; 18(5):525. Abstract
submitted by kickingbird at May, 2, 2026 from Viruses. 2026; 18(5):525 (via https://www.mdpi.com/1999-4915/18/5/525)
The H5N1 subtype of highly pathogenic avian influenza (HPAI) poses a major zoonotic threat due to its high fatality rate and capacity for cross species transmission. In early 2025, Argentina detected a ... Mingyue Wang, etc.,al. A novel self-amplified RNA vaccine co-expressing NA and HA1 delivered by Salmonella confers potent protection against H9N2 influenza in chickens. Poultry Science. Abstract
submitted by kickingbird at May, 2, 2026 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
The ongoing evolution of the H9N2 avian influenza virus presents a growing threat to both the poultry industry and public health. In this context, vaccination is not only a vital preventive measure but ... Min Zhu, etc.,al. Canine influenza virus at the human-animal interface: origins, adaptive evolution, and implications for public health. Virology. Abstract
submitted by kickingbird at May, 2, 2026 from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Canine influenza virus (CIV), an important lineage of influenza A virus (IAV) adapted to canine hosts, has emerged as a significant concern in zoonotic disease control. In recent years, CIV has exhibited ... Fathelrahman E, Mohamed Ali M, Challa TG, Osman R,. Modeling and assessing Highly Pathogenic Avian Influenza (HPAI) spread, epidemiological control measures, and cost. PLoS One. 2026 Apr 30;21(4):e0340004. Abstract
submitted by kickingbird at May, 1, 2026 from PLoS One. 2026 Apr 30;21(4):e0340004 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Highly Pathogenic Avian Influenza (HPAI) is a highly contagious, transboundary disease that can affect animals and humans, posing significant health risks to both. This study aimed to prepare for a potential ... Wang M, Laison EKE, Philippsen T, Ghaemi S, Liu J,. Mechanistic modelling of highly pathogenic avian influenza: A scoping review revealing critical gaps in cross-species transmission models. PLoS One. 2026 Apr 30;21(4):e0347929. Abstract
submitted by kickingbird at May, 1, 2026 from PLoS One. 2026 Apr 30;21(4):e0347929 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Background: Highly pathogenic avian influenza (HPAI) viruses, particularly subtypes such as H5N1 and H7N9, have caused widespread outbreaks in wild birds, poultry, livestock and occasionally humans, raising ... Daines R, Sadeyen J, Chang P, Iqbal M. 0. Mapping hemagglutinin residues driving antigenic diversity in H5Nx avian influenza viruses. J Virol 0:e00095-26. Abstract
submitted by kickingbird at May, 1, 2026 from J Virol 0:e00095-26 (via https://journals.asm.org/doi/10.1128/jvi.00095-26)
Since its emergence in 1996, the H5 avian influenza virus (AIV) A/Goose/Guangdong/1/1996 (Gs/GD) hemagglutinin (HA) has evolved into over 30 genetically and antigenically distinct clades, including the ... Wang W, Xing J, Jiang H, Lu F, Huang H, Zhang Y, S. Human infections with avian influenza A(H5) viruses with potential pandemic risk: 1997-2025. Natl Sci Rev. 2025 Nov 10;13(7):nwaf471. Abstract
submitted by kickingbird at May, 1, 2026 from Natl Sci Rev. 2025 Nov 10;13(7):nwaf471 (via https://academic.oup.com/nsr/article/doi/10.1093/nsr/nwaf471)
Highly pathogenic avian influenza (HPAI) A(H5) viruses have caused sporadic human infections since 1997, with recent detections in the Americas and Asia. However, the evolutionary dynamics of different ... Ashraf M, Boivin W, Nguyen-Van-Tam JS, Nolan T, St. Development of an adjuvanted, higher-dose, cell-based influenza vaccine: combining advanced technologies to improve vaccine effectiveness. Expert Rev Vaccines. 2026 Apr 29:2667732. Abstract
submitted by kickingbird at May, 1, 2026 from Expert Rev Vaccines. 2026 Apr 29:2667732 (via https://www.tandfonline.com/doi/full/10.1080/14760584.2026.2)
Introduction: Influenza remains a significant public health burden, particularly for high-risk populations such as older adults and those with chronic diseases. Effectiveness of standard-dose egg-grown ... Wongnak P, Seers T, Jittamala P, Imwong M, Schilli. Characterizing viral clearance kinetics in acute influenza. Philos Trans R Soc Lond B Biol Sci. 2026 Apr 30;38. Abstract
submitted by kickingbird at May, 1, 2026 from Philos Trans R Soc Lond B Biol Sci. 2026 Apr 30;38 (via https://royalsocietypublishing.org/rstb/article/381/1949/202)
Pharmacometric assessment of antiviral efficacy in acute influenza informs treatment decisions and pandemic preparedness. We characterized natural viral clearance in acute influenza to guide phase II trial ... Sun X, Belser JA, Li Z-N, Liu F, Brock N, Pulit-Pe. Prior immunity to seasonal influenza A(H3N2) virus confers varying levels of cross-protection against challenge with clade 2.3.4.4b A(H5N1), A(H7N9), or A(H9N2) virus in a ferret model. Microbiol Spectr. 2026 Apr 30:e0397425. Abstract
submitted by kickingbird at May, 1, 2026 from Microbiol Spectr. 2026 Apr 30:e0397425 (via https://journals.asm.org/doi/10.1128/spectrum.03974-25)
Evaluating how prior immunity to seasonal influenza viruses influences subsequent zoonotic influenza A virus (IAV) infection in animal models is critical for pandemic preparedness. In this study, we investigated ... Shuk Hang Li, etc.,al. Childhood immunological imprinting of cross-subtype antibodies targeting the hemagglutinin head domain of influenza viruses. Cell Host & Microbe. Abstract
submitted by kickingbird at May, 1, 2026 from Cell Host & Microbe (via https://www.sciencedirect.com/science/article/abs/pii/S19313)
Influenza virus cross-subtype antibodies targeting epitopes in the hemagglutinin (HA) head are rare because these epitopes are variable between influenza virus subtypes. We found that a large proportion ... WHO. Influenza at the human-animal interface summary and assessment, 31 March 2026. WHO. Abstract
submitted by kickingbird at Apr, 30, 2026 from WHO (via https://cdn.who.int/media/docs/default-source/influenza/huma)
From 23 January to 31 March 2026, based on reporting date, detections of influenza A(H5N1) in four humans, influenza A(H9N2) in five humans, influenza A(H10N3) in one human, an influenza A(H1N1) variant ... Hao, J., Wang, P., Li, L. et al. Generation of an autophagy-targeting influenza A virus as live attenuated vaccine. Nat Commun (2026). Abstract
submitted by kickingbird at Apr, 30, 2026 from Nat Commun (2026) (via https://www.nature.com/articles/s41467-026-72426-4)
Despite existing vaccines, influenza remains a significant public health burden, highlighting the need for vaccine strategies with improved safety and efficacy. Here we develop an autophagy-targeting influenza. ... Scarvaglieri I, De Francesco MA, Alberti M, Cesane. Influenza A(H3N2) Subclade K: Epidemiology, Molecular Evolution and Vaccine Effectiveness in Europe. Pathogens. 2026; 15(5):474. Abstract
submitted by kickingbird at Apr, 30, 2026 from Pathogens. 2026; 15(5):474 (via https://www.mdpi.com/2076-0817/15/5/474)
Background: Influenza A(H3N2) viruses remain a major public health concern due to their rapid antigenic evolution and association with severe disease, particularly among high-risk populations. During the ... Tewari D, Sekhwal MK, Nicholson C, Killian ML, Zel. Genotype Diversity of Highly Pathogenic Avian Influenza H5N1 Clade 2.3.4.4b in Pennsylvania Poultry During Disease Outbreak from April 2022 to March 2023. Viruses. 2026; 18(5):502. Abstract
submitted by kickingbird at Apr, 30, 2026 from Viruses. 2026; 18(5):502 (via https://www.mdpi.com/1999-4915/18/5/502)
The 2022 highly pathogenic avian influenza (HPAI) outbreak of H5N1 clade 2.3.4.4b was one of the major avian influenza outbreaks, leading to multiple spillover events infecting domestic and wild bird flocks, ... Günther A, Herrmann C, Sehl-Ewert J, Piro S, Ahren. Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus and Mass Mortality in Eurasian Cranes, Germany, 2025. Emerg Infect Dis. 2026 May. Abstract
submitted by kickingbird at Apr, 30, 2026 from Emerg Infect Dis. 2026 May (via https://wwwnc.cdc.gov/eid/article/32/5/26-0170_article)
In autumn 2025, highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b virus, genotype EA-2024-DI.2.1, caused systemic infections leading to a mass mortality event among the western migrating subpopulation ... Meseko C, Zecchin B, Go-Maro EW, Dianati M, Mkpuma. Emergence and Rapid Spread of a New Reassortant High Pathogenicity H5N1 Clade 2.3.4.4b Avian Influenza Virus in Nigeria. Influenza Other Respir Viruses. 2026 May;20(5):e70. Abstract
submitted by kickingbird at Apr, 29, 2026 from Influenza Other Respir Viruses. 2026 May;20(5):e70 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70260)
Over the past two decades, West Africa has experienced recurrent incursions of Goose/Guangdong-lineage highly pathogenic avian influenza (HPAI) A(H5N1), with Nigeria as a hotspot for repeated introductions ... Xu, Y., Wan, X., Chen, M. et al. Influenza mRNA vaccine with engineered panhandle-forming UTRs provides potent, dose-sparing protection against seasonal influenza viruses. npj Vaccines (2026). Abstract
submitted by kickingbird at Apr, 29, 2026 from npj Vaccines (2026) (via https://www.nature.com/articles/s41541-026-01463-3)
Influenza viruses pose a persistent threat to global public health, causing widespread respiratory illness and significant morbidity. Vaccination remains the most effective strategy to reduce the burden ... 10273 items, 20/Page, Page[9/514][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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