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2025-12-5 20:43:09
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Benjamin A. Pinsky, Benjamin T. Bradley. Opportunities and challenges for the U.S. laboratory response to highly pathogenic avian influenza A(H5N1). Journal of Clinical Virology Vol 174 , Oct 2024.  Abstract  
submitted by kickingbird at Sep, 3, 2024 from Journal of Clinical Virology Vol 174 , Oct 2024 (via https://www.sciencedirect.com/science/article/pii/S138665322)
On March 25, 2024 an outbreak of highly pathogenic avian influenza (HPAI) A H5N1 was identified in dairy cows across multiple farms in the United States. Zoonotic cases originating in individuals with ...

Degtyarev E, Feoktistova S, Volchkov P, Deviatkin. Complex Evolutionary Dynamics of H5N8 Influenza A Viruses Revealed by Comprehensive Reassortment Analysis. Viruses. 2024; 16(9):1405.  Abstract  
submitted by kickingbird at Sep, 3, 2024 from Viruses. 2024; 16(9):1405 (via https://www.mdpi.com/1999-4915/16/9/1405)
Influenza A viruses (IAVs) circulate among different species and have the potential to cause significant pandemics in humans. This study focuses on reassortment events in the H5N8 subtype of IAV, which ...

Gào X, Sun Y, Shen P, Guo J, Chen Y, Yin Y, Liu Z,. Population-Based Influenza Vaccine Effectiveness Against Laboratory-Confirmed Influenza Infection in Southern China, 2023-2024 Season. Open Forum Infect Dis. 2024 Aug 21;11(9):ofae456.  Abstract  
submitted by kickingbird at Sep, 3, 2024 from Open Forum Infect Dis. 2024 Aug 21;11(9):ofae456 (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11365065/)
Background: In China, the 2022-2023 influenza season began earlier and was characterized by higher levels of influenza activity and co-circulation of various respiratory pathogens compared with seasons ...

Hatuwal B, Goel V, Deliberto TJ, Lowe J, Emch M, W. Spatial patterns of influenza A virus spread across compartments in commercial swine farms in the United States. Emerg Microbes Infect. 2024 Sep 2:2400530.  Abstract  
submitted by kickingbird at Sep, 3, 2024 from Emerg Microbes Infect. 2024 Sep 2:2400530 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Multiple genetic variants of H1 and H3 influenza A viruses (IAVs) circulate concurrently in US swine farms. Understanding the spatial transmission patterns of IAVs among these farms is crucial for developing ...

Bordes L, Germeraad EA, Roose M, van Eijk NMHA, En. Experimental infection of Chickens, Pekin ducks, Eurasian wigeons and Barnacle geese with two recent highly pathogenic avian influenza H5N1 clade 2.3.4.4b viruses. Emerg Microbes Infect. 2024 Sep 2:2399970.  Abstract  
submitted by kickingbird at Sep, 3, 2024 from Emerg Microbes Infect. 2024 Sep 2:2399970 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Multiple genotypes of highly pathogenic avian influenza (HPAI) H5 clade 2.3.4.4b viruses have caused epizootics in wild birds and poultry. The HPAI H5N1 genotype C virus caused a modest epizootic, whereas ...

Wang P, Guo J, Zhou Y, Zhu M, Fang S, Sun F, Huang. The C-terminal amino acid motifs of NS1 protein affect the replication and virulence of naturally NS-truncated H1N1 canine influenza virus. Emerg Microbes Infect. 2024 Sep 2:2400546.  Abstract  
submitted by kickingbird at Sep, 3, 2024 from Emerg Microbes Infect. 2024 Sep 2:2400546 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
The vast majority of data obtained from sequence analysis of influenza A viruses (IAVs) have revealed that nonstructural 1 (NS1) proteins from H1N1 swine, H3N8 equine, H3N2 avian and the correspondent ...

Daniel Higgins, etc.,al. [preprint]Introducing a framework for within-host dynamics and mutations modelling of H5N1 influenza infection in humans. https://doi.org/10.1101/2024.09.01.24312235.  Abstract  
submitted by kickingbird at Sep, 3, 2024 from https://doi.org/10.1101/2024.09.01.24312235 (via https://www.medrxiv.org/content/10.1101/2024.09.01.24312235v)
Avian influenza A(H5N1) poses a risk to public health due to its pandemic potential should the virus mutate to become human-to-human transmissible. To date, reported influenza A(H5N1) human cases have ...

Joel Armando Vázquez-Pérez, etc.,al. [preprint]First laboratory-confirmed human case of infection with influenza A(H5N2) virus reported in Mexico. https://doi.org/10.1101/2024.08.15.24311897.  Abstract  
submitted by kickingbird at Sep, 3, 2024 from https://doi.org/10.1101/2024.08.15.24311897 (via https://www.medrxiv.org/content/10.1101/2024.08.15.24311897v)
In late April, 2024, we detected a non-subtypeable influenza virus in a hospitalized patient, resident of the Metropolitan area of Mexico City. Our results using 5 complete viral segments M, NS, NA, NP ...

Foong Ying Wong, etc.,al. [preprint]Highly pathogenic avian influenza H5 virus exposure in goats and sheep. https://doi.org/10.1101/2024.08.31.610397.  Abstract  
submitted by kickingbird at Sep, 2, 2024 from https://doi.org/10.1101/2024.08.31.610397 (via https://www.biorxiv.org/content/10.1101/2024.08.31.610397v1)
The recent outbreaks of highly pathogenic avian influenza A(H5N1) virus in North and South America, including widespread infection of cattle in the United States, calls for an urgent assessment of the ...

Claire Guinat, etc.,al. [preprint]Promising effects of duck vaccination against highly pathogenic avian influenza, France 2023~24. https://doi.org/10.1101/2024.08.28.609837.  Abstract  
submitted by kickingbird at Sep, 2, 2024 from https://doi.org/10.1101/2024.08.28.609837 (via https://www.biorxiv.org/content/10.1101/2024.08.28.609837v1)
The ongoing panzootic of highly pathogenic avian influenza (HPAI) H5 clade 2.3.4.4b has caused widespread poultry mortality and raised concerns about zoonotic pandemics and wildlife conservation. France ...

Huang X, Cheng Z, Lv Y, Li W, Liu X, Huang W, Zhao. Neutralization potency of the 2023-24 seasonal influenza vaccine against circulating influenza H3N2 strains. Hum Vaccin Immunother. 2024 Dec 31;20(1):2380111.  Abstract  
submitted by kickingbird at Sep, 2, 2024 from Hum Vaccin Immunother. 2024 Dec 31;20(1):2380111 (via https://www.tandfonline.com/doi/full/10.1080/21645515.2024.2)
Seasonal influenza is a severe disease that significantly impacts public health, causing millions of infections and hundreds of thousands of deaths each year. Seasonal influenza viruses, particularly the ...

Fan, Y., Nishimura, H., Sakata, S. et al. Minimal influenza virus transmission from touching contaminated face masks: a laboratory study. Sci Rep 14, 20211 (2024).  Abstract  
submitted by kickingbird at Sep, 1, 2024 from Sci Rep 14, 20211 (2024) (via https://www.nature.com/articles/s41598-024-70615-z#citeas)
The risk of virus transmission via the touching of contaminated masks has long been assumed by infection control teams. Yet, robust evidence to support this belief has been lacking. This risk was investigated ...

Drehoff CC, White EB, Frutos AM, et al. Cluster of Influenza A(H5) Cases Associated with Poultry Exposure at Two Facilities - Colorado, July 2024. MMWR Morb Mortal Wkly Rep 2024;73:734–739.  Abstract  
submitted by kickingbird at Aug, 30, 2024 from MMWR Morb Mortal Wkly Rep 2024;73:734–739 (via https://www.cdc.gov/mmwr/volumes/73/wr/mm7334a1.htm?s_cid=mm)
Persons who work in close contact with dairy cattle and poultry that are infected with highly pathogenic avian influenza (HPAI) A(H5N1) virus are at increased risk for infection. In July 2024, the Colorado ...

Goodwin E, Gibbs JS, Yewdell JW, Eisenlohr LC, Hen. Influenza virus antibodies inhibit antigen-specific de novo B cell responses in mice. J Virol. 2024 Aug 28:e0076624.  Abstract  
submitted by kickingbird at Aug, 29, 2024 from J Virol. 2024 Aug 28:e0076624 (via https://journals.asm.org/doi/10.1128/jvi.00766-24)
Antibody responses to influenza vaccines tend to be focused on epitopes encountered during prior influenza exposures, with little production of de novo responses to novel epitopes. To examine the contribution ...

Schughart K, Smith AM, Tsalik EL, Threlkeld SC, Se. Host response to influenza infections in human blood: association of influenza severity with host genetics and transcriptomic response. Front Immunol. 2024 Aug 13;15:1385362.  Abstract  
submitted by kickingbird at Aug, 28, 2024 from Front Immunol. 2024 Aug 13;15:1385362 (via https://www.frontiersin.org/journals/immunology/articles/10.)
Introduction: Influenza virus infections are a major global health problem. Influenza can result in mild/moderate disease or progress to more severe disease, leading to high morbidity and mortality. Severity ...

Kutkat O, Gomaa M, Moatasim Y, Taweel AE, Kamel MN. Highly Pathogenic Avian Influenza Virus H5N1 clade 2.3.4.4b in Wild Rats in Egypt during 2023. Emerg Microbes Infect. 2024 Aug 28:2396874.  Abstract  
submitted by kickingbird at Aug, 28, 2024 from Emerg Microbes Infect. 2024 Aug 28:2396874 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Avian influenza viruses (AIVs) pose continuous challenges to human and animal health worldwide. Wild birds are considered the natural reservoir for AIVs and play a major role in spreading influenza viruses ...

Zhao X, Gu Y, Tang X, Jiang C, Fang F, Chu W, Tao. Whole-genome analysis of circulating influenza A virus (H3N2) strains in Shanghai, China from 2005 to 2023. Emerg Microbes Infect. 2024 Aug 28:2396867.  Abstract  
submitted by kickingbird at Aug, 28, 2024 from Emerg Microbes Infect. 2024 Aug 28:2396867 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Seasonal influenza A virus subtype H3N2 (A/H3N2) circulates globally and has been linked to higher hospitalization rates and summer outbreaks in temperate regions. Here, A/H3N2 circulation in Shanghai, ...

Zhang X, Wu J, Wang Y, Hao M, Liu H, Fan S, et al. Highly Pathogenic Avian Influenza A Virus in Wild Migratory Birds, Qinghai Lake, China, 2022. Emerg Infect Dis. 2024 Oct.  Abstract  
submitted by kickingbird at Aug, 28, 2024 from Emerg Infect Dis. 2024 Oct (via https://wwwnc.cdc.gov/eid/article/30/10/24-0460_article)
In July 2022, an outbreak of highly pathogenic avian influenza A(H5N1) virus clade 2.3.4.4b occurred among migratory birds at Qinghai Lake in China. The virus circulated in June, and reassortants emerged ...

Din GU, Wu C, Tariq Z, Hasham K, Amjad MN, Shen B,. Unlocking influenza B: exploring molecular biology and reverse genetics for epidemic control and vaccine innovation. Virol J. 2024 Aug 23;21(1):196.  Abstract  
submitted by kickingbird at Aug, 27, 2024 from Virol J. 2024 Aug 23;21(1):196 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Influenza is a highly contagious acute viral illness that affects the respiratory system, posing a significant global public health concern. Influenza B virus (IBV) causes annual seasonal epidemics. The ...

Gao Y, Guyatt G, Uyeki TM, Liu M, Chen Y, Zhao Y,. Antivirals for treatment of severe influenza: a systematic review and network meta-analysis of randomised controlled trials. Lancet. 2024 Aug 24;404(10454):753-763.  Abstract  
submitted by kickingbird at Aug, 27, 2024 from Lancet. 2024 Aug 24;404(10454):753-763 (via https://www.thelancet.com/journals/lancet/article/PIIS0140-6)
Background: The optimal antiviral drug for treatment of severe influenza remains unclear. To support updated WHO influenza clinical guidelines, this systematic review and network meta-analysis evaluated ...

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