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2026-6-10 16:56:57
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Lite TL, Goya S, Davis ML, Morris AE, Bryson-Cahn. Human Infection with Highly Pathogenic Avian Influenza A(H5N5) Virus. N Engl J Med. 2026 May 7.  Abstract  
submitted by kickingbird at May, 8, 2026 from N Engl J Med. 2026 May 7 (via https://www.nejm.org/doi/10.1056/NEJMc2518178)
Sporadic human infections with avian influenza A viruses have caused a wide spectrum of illness. As these novel influenza A viruses pose pandemic potential, timely detection and characterization of such ...

Lemaitre J, Lessler J. [preprint]Generative diffusion models for spatiotemporal influenza forecasting. ArXiv [Preprint]. 2026 Apr 27:arXiv:2604.24913v1.  Abstract  
submitted by kickingbird at May, 8, 2026 from ArXiv [Preprint]. 2026 Apr 27:arXiv:2604.24913v1 (via https://arxiv.org/abs/2604.24913v1)
Forecasting infectious disease incidence can provide important information to guide public health planning, yet is difficult because epidemic dynamics are complex. Current mechanistic and statistical approaches ...

Chanchaidechachai T, Stegeman A, Velkers FC, Gonza. Assessing the impact of outdoor farming, farm size, and farm density on highly pathogenic avian influenza epidemics: A modelling study in the Netherlands. One Health. 2026 Apr 22;22:101424.  Abstract  
submitted by kickingbird at May, 8, 2026 from One Health. 2026 Apr 22;22:101424 (via https://www.sciencedirect.com/science/article/pii/S235277142)
Poultry farming in the Netherlands is moving toward more extensive systems to promote animal welfare, a shift that has led to the rising number of organic and free-range farms, which provide poultry with ...

Ries HJ, Lalli J, Florek KR, Barlow S, Goss M, et. Weak selection and stochastic processes limit the emergence of antigenic variants during household transmission of influenza A viruses. PLOS Pathogens 22(5): e1013689.  Abstract  
submitted by kickingbird at May, 8, 2026 from PLOS Pathogens 22(5): e1013689 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza viruses undergo antigenic drift, the gradual accumulation of mutations that cause antigenic changes in the viral surface proteins hemagglutinin (HA) and neuraminidase (NA). Although selection ...

Jude V. Lane, etc.,al. HPAI drives a fourfold increase in adult gannet mortality which requires two decades recovery time. Biological Conservation.  Abstract  
submitted by kickingbird at May, 8, 2026 from Biological Conservation (via https://www.sciencedirect.com/science/article/pii/S000632072)
Wildlife disease outbreaks are increasing, representing a growing threat to biodiversity. Despite this, their demographic cost and recover times are poorly quantified. In 2021, HPAI H5Nx viruses entered ...

Linxi He, Daihai He. Sensitivity of Convergent Cross Mapping to temporal discontinuities: A case study of seasonal influenza in Hong Kong. Infectious Disease Modelling.  Abstract  
submitted by kickingbird at May, 8, 2026 from Infectious Disease Modelling (via https://www.sciencedirect.com/science/article/pii/S246804272)
Convergent cross mapping (CCM) method has been widely applied to investigate environmental drivers of infectious disease dynamics, particularly for seasonal influenza. However, its robustness to temporal ...

Schafers J, Warren CJ, Yang J, Zhang J, Cole SJ, C. Stability of influenza viruses in the milk of cows and sheep. J Gen Virol. 2026 May;107(5).  Abstract  
submitted by kickingbird at May, 8, 2026 from J Gen Virol. 2026 May;107(5) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
In late 2023, H5N1 high-pathogenicity avian influenza virus (HPAIV) started circulating in dairy cattle in the USA. High viral titres were detected in milk from infected cows, raising concerns about onward ...

Manoj S Nair, etc., al. Serum neutralisation of H5N1 clade 2.3.4.4b influenza is largely mediated by neuraminidase-directed antibodies. The Lancet Microbe.  Abstract  
submitted by kickingbird at May, 7, 2026 from The Lancet Microbe (via https://www.sciencedirect.com/science/article/pii/S266652472)
Highly pathogenic avian influenza A (H5N1) continues to circulate globally in avian and mammalian species. Since its emergence in 1997, over 1000 confirmed human infections with H5N1 have been reported, ...

Megan R. Miller, etc., al. Evaluation of PCR-Based H5N1 Influenza Detection Methods in Milk from an Inter-laboratory Comparison Study Demonstrating Method-Dependent Sensitivity Variability. Journal of Food Protection.  Abstract  
submitted by kickingbird at May, 7, 2026 from Journal of Food Protection (via https://www.sciencedirect.com/science/article/pii/S0362028X2)
Since March 2024, H5N1 highly pathogenic avian influenza (HPAI) has been detected in U.S. dairy cattle. Infectious virus shed in unpasteurized milk, a matrix not previously evaluated for H5N1 detection, ...

Kun Xiao, Yan Cao, Zhihai Han, Qian Da, Yun Feng,. A large-scale single-cell atlas reveals the pulmonary immune panorama in adult patients with influenza. Am J Respir Crit Care Med. 2026 Mar 16:aamag122.  Abstract  
submitted by kickingbird at May, 6, 2026 from Am J Respir Crit Care Med. 2026 Mar 16:aamag122 (via https://academic.oup.com/ajrccm/advance-article-abstract/doi)
Rationale: The host immune determinants that distinguish protective from life-threatening responses to influenza are poorly understood. Identifying drivers of immunopathology in the human lung is critical ...

Campbell AJ, Shephard M, Paulos AP, Pauly MD, Vu M. Surveillance on California dairy farms reveals multiple possible sources of H5N1 influenza virus transmission. PLoS Biol . 2026 May 5;24(5):e3003761.  Abstract  
submitted by kickingbird at May, 6, 2026 from PLoS Biol . 2026 May 5;24(5):e3003761 (via https://journals.plos.org/plosbiology/article?id=10.1371/jou)
Transmission routes of highly pathogenic H5N1 between cows or to humans remain unclear due to limited data from affected dairy farms. We performed air, farm wastewater, and milk sampling on 14 H5N1-positive ...

Xingyi Li, etc.,al. FluNexus: A versatile web platform for antigenic prediction and visualization of influenza A viruses. iMeta.  Abstract  
submitted by kickingbird at May, 5, 2026 from iMeta (via https://onlinelibrary.wiley.com/doi/10.1002/imt2.70127)
Influenza A viruses pose a major global health threat due to their high mutation rates, broad host ranges, and pandemic potential. Human seasonal influenza is primarily driven by H1 and H3 subtypes, which ...

Liu, H., Li, X., Sun, N. et al. Spatiotemporal instability of influenza seasonality during viral co-circulation. npj Syst Biol Appl (2026).  Abstract  
submitted by kickingbird at May, 5, 2026 from npj Syst Biol Appl (2026) (via https://www.nature.com/articles/s41540-026-00729-9)
Co-circulation of multiple influenza subtypes poses a major challenge to global public health. However, its specific impact on non-stationary epidemic sequences and coupling relationships with environmental ...

Mengting Huang, etc.,al. Enhanced Immunogenicity and Dose-Sparing Efficacy of SelfAmplifying RNA Vaccines Against Seasonal Influenza Across Subtypes. Emerging Microbes & Infections.  Abstract  
submitted by kickingbird at May, 5, 2026 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2026.2)
Recent clinical data on seasonal influenza mRNA vaccines have demonstrated suboptimal efficacy against the influenza B virus (IBV). We employed sequence optimization strategies that successfully enhanced ...

C. Stenkamp-Strahm, etc.,al. A longitudinal study of influenza A viral detection in bulk tank and pen-level milk collected from dairy farms in California affected by Highly Pathogenic Avian Influenza H5N1. Journal of Dairy Science.  Abstract  
submitted by kickingbird at May, 5, 2026 from Journal of Dairy Science (via https://www.sciencedirect.com/science/article/pii/S002203022)
Highly pathogenic avian influenza virus H5N1 has been infecting dairy herds in the US since its initial incursion into cows in early 2024. Although national strategies have aimed to detect affected herds ...

Mingyue Wang, etc.,al. A novel self-amplified RNA vaccine co-expressing NA and HA1 delivered by Salmonella confers potent protection against H9N2 influenza in chickens. Poultry Science.  Abstract  
submitted by kickingbird at May, 5, 2026 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
The ongoing evolution of the H9N2 avian influenza virus presents a growing threat to both the poultry industry and public health. In this context, vaccination is not only a vital preventive measure but ...

Ghumra, D.P., Xu, M., Benegal, A. et al. Biofouling-resistant functionalized capacitive biosensor for rapid detection of zoonotic influenza. npj Biosensing 3, 27 (2026).  Abstract  
submitted by kickingbird at May, 5, 2026 from npj Biosensing 3, 27 (2026) (via https://www.nature.com/articles/s44328-026-00092-z)
Emerging zoonotic pathogens represent an escalating threat to global health, underscoring the need for rapid and effective testing strategies. Electrochemical biosensors offer a promising solution for ...

WPRO. Avian Influenza Weekly Update # 1043: 1 May 2026. WHO.  Abstract  
submitted by kickingbird at May, 4, 2026 from WHO (via https://www.who.int/westernpacific/publications/m/item/avian)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ...

Flagg M, Winski CJ, Brackney BG, Lutterman TR, Ort. Replication Efficiency of Contemporary Highly Pathogenic Avian Influenza A(H5N1) Virus Isolates in Human Nasal Epithelium Model. Emerg Infect Dis. 2026 May.  Abstract  
submitted by kickingbird at May, 4, 2026 from Emerg Infect Dis. 2026 May (via https://wwwnc.cdc.gov/eid/article/32/5/26-0053_article)
Replication of influenza A virus in human nasal epithelium affects transmissibility and disease. We compared virus replication and immune responses in human nasal epithelium infected with seasonal and ...

Dressler Aparna, Wagner-Wiening Christiane, Teg. Highly pathogenic avian influenza A(H5N1) in poultry and domestic cats and occupational exposure among veterinary and other first responders, Germany, February 2026. Euro Surveill. 2026;31(17):pii=2600293.  Abstract  
submitted by kickingbird at May, 3, 2026 from Euro Surveill. 2026;31(17):pii=2600293 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
In February 2026, a highly pathogenic avian influenza (HPAI) A(H5N1) outbreak in a poultry holding in Sigmaringen, Germany, affected poultry and domestic cats, with infection confirmed by RT-qPCR. A One ...

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