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2026-2-1 22:30:43
Article

Figueroa T, Bessière P, Coggon A, Bouwman KM, van. The Microbiota Contributes to the Control of Highly Pathogenic H5N9 Influenza Virus Replication in Ducks. J Virol. 2020 May 4;94(10):e00289-20.  Abstract  
submitted by kickingbird at Jan, 28, 2025 from J Virol. 2020 May 4;94(10):e00289-20 (via https://journals.asm.org/doi/10.1128/jvi.00289-20)
Ducks usually show little or no clinical signs following highly pathogenic avian influenza virus infection. In order to analyze whether the microbiota could contribute to the control of influenza virus ...

Yuk SS, To EO, Kwon JH, Noh JY, Hong WT, Jeong JH,. Optimization of inactivated H5N9 highly pathogenic avian influenza vaccine and inactivated Salmonella enterica serovar Typhimurium vaccine with antigen dose and prime-boost regimen in domestic ducks. Poult Sci. 2017 Sep 1;96(9):3079-3085.  Abstract  
submitted by kickingbird at Jan, 28, 2025 from Poult Sci. 2017 Sep 1;96(9):3079-3085 (via https://www.sciencedirect.com/science/article/pii/S003257911)
Owing to the increase in the number of diseases affecting ducks and the demand for food safety by consumers, vaccination has become one of the factors that influence duck meat productivity. The highly ...

Briand FX, Schmitz A, Ogor K, Le Prioux A, Guillou. Emerging highly pathogenic H5 avian influenza viruses in France during winter 2015/16: phylogenetic analyses and markers for zoonotic potential. Euro Surveill. 2017 Mar 2;22(9):30473.  Abstract  
submitted by kickingbird at Jan, 28, 2025 from Euro Surveill. 2017 Mar 2;22(9):30473 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Several new highly pathogenic (HP) H5 avian influenza virus (AIV) have been detected in poultry farms from south-western France since November 2015, among which an HP H5N1. The zoonotic potential and origin ...

Yu Y, Wang X, Jin T, Wang H, Si W, Yang H, Wu J, Y. Newly Emergent Highly Pathogenic H5N9 Subtype Avian Influenza A Virus. J Virol. 2015 Sep;89(17):8806-15.  Abstract  
submitted by kickingbird at Jan, 28, 2025 from J Virol. 2015 Sep;89(17):8806-15 (via https://journals.asm.org/doi/10.1128/jvi.00653-15)
The novel H7N9 avian influenza virus (AIV) was demonstrated to cause severe human respiratory infections in China. Here, we examined poultry specimens from live bird markets linked to human H7N9 infection ...

El-Shesheny R, Gomaa M, Sayes ME, Kamel MN, Taweel. Emergence of a novel reassortant highly pathogenic avian influenza clade 2.3.4.4b A(H5N2) Virus, 2024. Emerg Microbes Infect. 2025 Jan 27:2455601.  Abstract  
submitted by kickingbird at Jan, 28, 2025 from Emerg Microbes Infect. 2025 Jan 27:2455601 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Reassortant highly pathogenic avian influenza A(H5N2) clade 2.3.4.4.b viruses were detected from ducks and environmental samples in Egypt, June 2024. Genomic and phylogenetic analyses revealed a novel ...

Postel A, Gremmel N, Lydersen C, Kovacs KM, Schick. Highly pathogenic avian influenza virus (H5N5) detected in an Atlantic walrus (Odobenus rosmarus rosmarus) in the Svalbard Archipelago, Norway, 2023. Emerg Microbes Infect. 2025 Jan 27:2456146.  Abstract  
submitted by kickingbird at Jan, 28, 2025 from Emerg Microbes Infect. 2025 Jan 27:2456146 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
We present the first documented case of highly pathogenic avian influenza virus (HPAIV) subtype H5N5 in an Atlantic walrus (Odobenus rosmarus rosmarus). The animal was found dead in Svalbard, Norway, in ...

Smith S, Rayner JO, Kim JH. Fluorofurimazine, a novel NanoLuc substrate, enhances real-time tracking of influenza A virus infection without altering pathogenicity in mice. Microbiol Spectr. 2025 Jan 27:e0268924.  Abstract  
submitted by kickingbird at Jan, 28, 2025 from Microbiol Spectr. 2025 Jan 27:e0268924 (via https://journals.asm.org/doi/10.1128/spectrum.02689-24)
Bioluminescence imaging (BLI) using engineered bioluminescent viruses has emerged as a powerful tool for real-time, noninvasive monitoring of viral replication in living animals. While traditional luciferase-based ...

Zhang Y, Wu J, Lin Q, Ou J, Qi X, Zheng Y, Li F, W. Infection Tracing and Virus Genomic Analysis of Two Cases of Human Infection with Avian Influenza A(H5N6) - Fujian Province, China, April-May 2024. China CDC Wkly. 2025 Jan 17;7(3):107-112.  Abstract  
submitted by kickingbird at Jan, 28, 2025 from China CDC Wkly. 2025 Jan 17;7(3):107-112 (via https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2024)
What is known about this topic?: Global human cases of zoonotic influenza A(H5N6) have increased significantly in recent years, primarily due to widespread circulation of clade 2.3.4.4b virus since 2020. ...

Gu J, Yan Y, Zeng Z, Liu D, Hu J, Hu S, Wang X, Gu. Hemagglutinin with a polybasic cleavage site confers high virulence on H7N9 avian influenza viruses. Poult Sci. 2025 Jan 18;104(2):104832.  Abstract  
submitted by kickingbird at Jan, 27, 2025 from Poult Sci. 2025 Jan 18;104(2):104832 (via https://www.sciencedirect.com/science/article/pii/S003257912)
H7N9 avian influenza virus (AIV) first emerged in February 2013 in China, and early isolates were all low pathogenic (LP). After circulation for a few years in live poultry markets of China, LP H7N9 AIVs ...

Katharina Daniel, etc.,al. [preprint]Detection of low pre-existing humoral immunity against influenza virus H5N1 clade 2.3.4.4b in unexposed individuals. https://doi.org/10.1101/2025.01.22.634277.  Abstract  
submitted by kickingbird at Jan, 26, 2025 from https://doi.org/10.1101/2025.01.22.634277 (via https://www.biorxiv.org/content/10.1101/2025.01.22.634277v1)
The repeated spill-over of Influenza A virus H5N1 clade 2.3.4.4b from cattle to humans highlights the risk of a human H5N1 pandemic. Given the impact of pre-existing immunity on the course and severity ...

Caliendo V, Bellido Martin B, Fouchier RAM, Verdaa. Highly Pathogenic Avian Influenza Contributes to the Population Decline of the Peregrine Falcon (Falco peregrinus) in The Netherlands. Viruses. 2024 Dec 27;17(1):24.  Abstract  
submitted by kickingbird at Jan, 26, 2025 from Viruses. 2024 Dec 27;17(1):24 (via https://www.mdpi.com/1999-4915/17/1/24)
Highly pathogenic avian influenza (HPAI) epizootics have caused repeated mass mortality events among wild birds. The effect of the infection is potentially detrimental for a variety of bird species, including ...

Alvarez I, Banihashem F, Persson A, Hurri E, Kim H. Detection and Phylogenetic Characterization of Influenza D in Swedish Cattle. Viruses. 2024 Dec 26;17(1):17.  Abstract  
submitted by kickingbird at Jan, 26, 2025 from Viruses. 2024 Dec 26;17(1):17 (via https://www.mdpi.com/1999-4915/17/1/17)
Increased evidence suggests that cattle are the primary host of Influenza D virus (IDV) and may contribute to respiratory disease in this species. The aim of this study was to detect and characterise IDV ...

Sheikh, M.O.B., Rashid, P.M.A., Rahim, Z.H. et al. Molecular characterization and genetic analysis of highly pathogenic H5N1 clade 2.3.4.4b in seagulls from Dukan Lake, Iraq. Virus Genes (2025).  Abstract  
submitted by kickingbird at Jan, 24, 2025 from Virus Genes (2025) (via https://link.springer.com/article/10.1007/s11262-025-02133-7)
Avian influenza virus (AIV) remains a significant global threat, with periodic reemergence in Iraq. This study marks the first molecular characterization of the highly pathogenic avian influenza (HPAI) ...

Good MR, Suja D, Guthmiller JJ. The sweet side of H5N1 influenza virus infection. PLoS Pathog 21(1): e1012847.  Abstract  
submitted by kickingbird at Jan, 24, 2025 from PLoS Pathog 21(1): e1012847 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
H5Nx viruses remain a threat to human health. Over the past few years, the H5Nx clade 2.3.4.4b has rapidly spread to 6 continents, leading to massive avian and mammalian host deaths. In late March 2024, ...

Zhang M, Zeng Z, Chen X, Wang G, Cai X, Hu Z, Gu M. Phosphorylation of PA at serine 225 enhances viral fitness of the highly pathogenic H5N1 avian influenza virus in mice. Vet Microbiol. 2025 Jan 20;302:110400.  Abstract  
submitted by kickingbird at Jan, 24, 2025 from Vet Microbiol. 2025 Jan 20;302:110400 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Currently, there is increasing spillover of highly pathogenic H5N1 avian influenza virus (AIV) to mammals, raising a concern of pandemic threat about this virus. Although the function of PA protein of ...

Song H, Hao T, Han P, Wang H, Zhang X, Li X, Wang. Receptor binding, structure, and tissue tropism of cattle-infecting H5N1 avian influenza virus hemagglutinin. Cell. 2025 Jan 22:S0092-8674(25)00048-0.  Abstract  
submitted by kickingbird at Jan, 24, 2025 from Cell. 2025 Jan 22:S0092-8674(25)00048-0 (via https://www.cell.com/cell/abstract/S0092-8674(25)00048-0)
The ongoing circulation of highly pathogenic avian influenza (HPAI) A (H5N1) viruses, particularly clade 2.3.4.4b strains, poses a significant threat to animal and public health. Recent outbreaks in cattle ...

Sun R, Feng X, Huang J, Zheng F, Xie R, Zhang C, Z. Characterization of novel highly pathogenic avian influenza A(H5N6) clade 2.3.4.4b virus in wild birds, East China, 2024. Virol Sin. 2025 Jan 21:S1995-820X(25)00002-1.  Abstract  
submitted by kickingbird at Jan, 24, 2025 from Virol Sin. 2025 Jan 21:S1995-820X(25)00002-1 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Highlights?We reported a novel H5N6 HPAIV belonging to clade 2.3.4.4b in wild birds in eastern China.?The novel H5N6 HPAIV most likely descended from clade 2.3.4.4b H5N1 virus in Japan.?The novel H5N6 ...

Yang Z, Ren ZD, Wang J, Dong W. Based on the MaxEnt model the analysis of influencing factors and simulation of potential risk areas of human infection with avian influenza A (H7N9) in China. Front Cell Infect Microbiol. 2025 Jan 3;14:1496991.  Abstract  
submitted by kickingbird at Jan, 21, 2025 from Front Cell Infect Microbiol. 2025 Jan 3;14:1496991 (via https://www.frontiersin.org/journals/cellular-and-infection-)
Exposure to infected animals and their contaminated environments may be the primary cause of human infection with the H7N9 avian influenza virus. However, the transmission characteristics and specific ...

WPRO. WPRO/WHO: Avian Influenza Weekly Update, 17 January 2025. WHO.  Abstract  
submitted by kickingbird at Jan, 20, 2025 from WHO (via https://cdn.who.int/media/docs/default-source/wpro---documen)
From 10 to 16 January 2025, one new case of human infection with avian influenza A(H5N1) virus was reported to WHO in the Western Pacific Region. The case is a 28-year-old male from Kampong Cham Province, ...

Ziegler E, Matthes KL, Middelkamp PW, Schuenemann. Retrospective modelling of the disease and mortality burden of the 1918-1920 influenza pandemic in Zurich, Switzerland. Epidemics. 2025 Jan 11;50:100813.  Abstract  
submitted by kickingbird at Jan, 19, 2025 from Epidemics. 2025 Jan 11;50:100813 (via https://www.sciencedirect.com/science/article/pii/S175543652)
Background: Our study aims to enhance future pandemic preparedness by integrating lessons from historical pandemics, focusing on the multidimensional analysis of past outbreaks. It addresses the gap in ...

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