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2026-2-1 16:51:15
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Osman, M.K., Robert, J., Broich, L. et al. The bat influenza A virus subtype H18N11 induces nanoscale MHCII clustering upon host cell attachment. Nat Commun 16, 3847 (2025).  Abstract  
submitted by kickingbird at Apr, 27, 2025 from Nat Commun 16, 3847 (2025) (via https://www.nature.com/articles/s41467-025-58834-y)
Prior to the discovery of bat influenza A virus (IAV) subtypes H17N10 and H18N11, all IAVs were thought to bind sialic acid residues via hemagglutinin (HA) to mediate attachment and subsequent viral entry. ...

Thao-Quyen Nguyen et al. Emergence and interstate spread of highly pathogenic avian influenza A(H5N1) in dairy cattle in the United States. Science, 388,eadq0900(2025).  Abstract  
submitted by kickingbird at Apr, 25, 2025 from Science, 388,eadq0900(2025) (via https://www.science.org/doi/10.1126/science.adq0900)
INTRODUCTIONHighly pathogenic avian influenza (HPAI) viruses have critical consequences for animal health and the agricultural economy—and may have pandemic potential. HPAI related to the goose/Guangdong ...

Elizabeth Billington, etc.,al. [preprint]Investigating Factors Driving Shifts in Subtype Dominance within H5Nx Clade 2.3.4.4b High-Pathogenicity Avian Influenza viruses. https://doi.org/10.1101/2025.04.23.650244.  Abstract  
submitted by kickingbird at Apr, 25, 2025 from https://doi.org/10.1101/2025.04.23.650244 (via https://www.biorxiv.org/content/10.1101/2025.04.23.650244v1)
H5Nx clade 2.3.4.4b high-pathogenicity avian influenza viruses (HPAIVs) have decimated wild bird and poultry populations globally since the autumn of 2020. In the United Kingdom (UK) and in continental ...

Huiru Li, etc.,al. [preprint]Development a computational framework for risk evaluation of emerging flu viruses based on genomic sequences and AI. https://doi.org/10.1101/2025.04.18.649608.  Abstract  
submitted by kickingbird at Apr, 25, 2025 from https://doi.org/10.1101/2025.04.18.649608 (via https://www.biorxiv.org/content/10.1101/2025.04.18.649608v1)
The recent resurgence of highly pathogenic avian influenza H5N1 viruses in North America and Europe has heightened global concerns regarding potential influenza pandemics. Despite significant progress ...

Di Pietra G, Munegato D, Poletto C, Conciatori V,. Surveillance of influenza viruses circulating from 2017/2018 to 2023/2024 seasons in Veneto Region, North-East Italy. Virol J. 2025 Apr 24;22(1):114.  Abstract  
submitted by kickingbird at Apr, 25, 2025 from Virol J. 2025 Apr 24;22(1):114 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: In Italy, influenza viruses typically circulate from October to April, causing seasonal epidemics. The pattern of influenza virus circulation varies each season regarding the timing of the ...

Onidje E, Oni OO, Kadja MC, Abraham MB, Burimuah V. Seroprevalence of H9N2 and H5 avian influenza in mixed-species poultry farms in Northern Benin. J Immunoassay Immunochem. 2025 Apr 24:1-15.  Abstract  
submitted by kickingbird at Apr, 25, 2025 from J Immunoassay Immunochem. 2025 Apr 24:1-15 (via https://www.tandfonline.com/doi/full/10.1080/15321819.2025.2)
Avian influenza is one of the major threats to poultry and human health in northern Benin, while mixed-species farming systems increase the risks of viral transmission. The present study estimated the ...

Islam A, Amin E, Khan MA, Islam M, Gupta SD, Abedi. Epidemiology and evolutionary dynamics of H9N2 avian influenza virus in Bangladesh. Emerg Microbes Infect. 2025 Apr 24:2498574.  Abstract  
submitted by kickingbird at Apr, 25, 2025 from Emerg Microbes Infect. 2025 Apr 24:2498574 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Low pathogenicity avian influenza (LPAI) H9N2 has been enzootic in Bangladeshi poultry since 2006. H9N2 outbreaks can decrease egg production and growth and pose a risk to human health. The role of avian ...

Valentina Caliendo, Beatriz Bellido Martin, Ron A.. Highly Pathogenic Avian Influenza in Northern Fulmars (Fulmarus glacialis) in the Netherlands. J Wildl Dis (2025).  Abstract  
submitted by kickingbird at Apr, 24, 2025 from J Wildl Dis (2025) (via https://meridian.allenpress.com/jwd/article/doi/10.7589/JWD-)
We report highly pathogenic avian influenza H5 virus infection in 10 Northern Fulmars (Fulmarus glacialis) found dead throughout January and February 2024 in the Netherlands. Five birds were infected with ...

Xiaoxu Zeng, etc.,al. [preprint]Simultaneous environmental and human surveillance for avian influenza viruses A, H5, H7, H9 and H10 in East, Central and Southwest China. https://doi.org/10.21203/rs.3.rs-6045605/v1.  Abstract  
submitted by kickingbird at Apr, 24, 2025 from https://doi.org/10.21203/rs.3.rs-6045605/v1 (via https://www.researchsquare.com/article/rs-6045605/v1)
Background The recent global rise in AIV outbreaks underscores the risk of transmission to humans. This study conducted surveillance to assess AIV circulation in poultry-related environments and patients ...

Gagandeep Singh, etc.,al. [preprint]Single-Cell Analysis of Host Responses in Bovine Milk Somatic Cells (bMSCs) Following HPAIV Bovine-H5N1 Influenza Infection. DOI:10.20944/preprints202504.0713.v1.  Abstract  
submitted by kickingbird at Apr, 24, 2025 from DOI:10.20944/preprints202504.0713.v1 (via https://www.preprints.org/manuscript/202504.0713/v1)
The 2024 outbreak of highly pathogenic avian influenza virus (HPAIV) H5N1 in U.S. dairy cattle presented an unprecedented scenario where the virus infected bovine mammary glands and was detected in milk, ...

Kim, S., Kim, MA., Kim, B. et al. Machine learning assessment of zoonotic potential in avian influenza viruses using PB2 segment. BMC Genomics 26, 395 (2025).  Abstract  
submitted by kickingbird at Apr, 24, 2025 from BMC Genomics 26, 395 (2025) (via https://link.springer.com/article/10.1186/s12864-025-11589-8)
BackgroundInfluenza A virus (IAV) is a major global health threat, causing seasonal epidemics and occasional pandemics. Particularly, Influenza A viruses from avian species pose significant zoonotic threats, ...

Rapi MC, Martin AMM, Lelli D, Lavazza A, Raimondi. Virological Passive Surveillance of Avian Influenza and Arboviruses in Wild Birds: A Two-Year Study (2023~2024) in Lombardy, Italy. Microorganisms. 2025; 13(5):958.  Abstract  
submitted by kickingbird at Apr, 24, 2025 from Microorganisms. 2025; 13(5):958 (via https://www.mdpi.com/2076-2607/13/5/958)
Avian influenza (AI), caused by Alphainfluenzavirus (family Orthomyxoviridae), poses significant threats to poultry, biodiversity, and public health. AI outbreaks in poultry lead to severe economic losses, ...

Liao X, Xie Q, Liang M, Liao Q, Huang B, Zhang S,. Glucosidase alpha neutral C promotes influenza virus replication by inhibiting proteosome-dependent degradation of hemagglutinin. Signal Transduct Target Ther. 2025 Apr 23;10(1):13.  Abstract  
submitted by kickingbird at Apr, 24, 2025 from Signal Transduct Target Ther. 2025 Apr 23;10(1):13 (via https://www.nature.com/articles/s41392-025-02227-6)
The H7N9 influenza virus poses a significant threat to human health, and the mechanism by which it infects humans remains incompletely understood. Our investigation has unveiled significant insights into ...

Lagan P, Lemon K. High Prevalence of Influenza D Virus Infection in Swine, Northern Ireland. Emerg Infect Dis. 2025 May.  Abstract  
submitted by kickingbird at Apr, 24, 2025 from Emerg Infect Dis. 2025 May (via https://wwwnc.cdc.gov/eid/article/31/5/24-1948_article)
We detected influenza D virus in multiple swine herds in Northern Ireland. Whole-genome sequencing showed several circulating genotypes and novel mutations in the receptor-binding site and esterase domains ...

Chen LL, Zhang X, Zhang K, Chan BP, Yuk Yuen JK, Y. Risk assessment of 2024 cattle H5N1 using age-stratified serosurveillance data. Emerg Microbes Infect. 2025 Apr 22:2497304.  Abstract  
submitted by kickingbird at Apr, 24, 2025 from Emerg Microbes Infect. 2025 Apr 22:2497304 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
The highly pathogenic avian influenza virus A(H5N1) clade 2.3.4.4b has caused a human outbreak in North America since March 2024. Here, we conducted a serosurveillance study to determine the risk of A(H5N1) ...

Yang L, Wang R, Liu Q, Shah T, Zhou J, Zhao W, Wan. Genomic Characterization and Phylogenetic Analysis of Five Avian Influenza H5N1 Subtypes from Wild Anser indicus in Yunnan, China. Vet Sci. 2025 Mar 17;12(3):280.  Abstract  
submitted by kickingbird at Apr, 24, 2025 from Vet Sci. 2025 Mar 17;12(3):280 (via https://www.mdpi.com/2306-7381/12/3/280)
Highly pathogenic avian influenza (HPAI) H5 viruses have been found to have a substantial geographic distribution since they were first reported in Guangdong Province, China. The emergence of new genotypes ...

Monto AS, Kuhlbusch K, Bernasconi C, Cao B, Cohen. Efficacy of Baloxavir Treatment in Preventing Transmission of Influenza. N Engl J Med. 2025 Apr 24;392(16):1582-1593.  Abstract  
submitted by kickingbird at Apr, 24, 2025 from N Engl J Med. 2025 Apr 24;392(16):1582-1593 (via https://www.nejm.org/doi/10.1056/NEJMoa2413156)
Background: Baloxavir marboxil (baloxavir) rapidly reduces influenza virus shedding, which suggests that it may reduce transmission. Studies of treatment with neuraminidase inhibitors have not shown sufficient ...

Blais-Savoie J, Yim W, Kotwa JD, Yip L, Kozak R, M. Screening of retail milk in Ontario for the presence of influenza A viral RNA. Can Commun Dis Rep. 2025 Apr 3;51(4):152-155.  Abstract  
submitted by kickingbird at Apr, 24, 2025 from Can Commun Dis Rep. 2025 Apr 3;51(4):152-155 (via https://www.canada.ca/content/dam/phac-aspc/documents/servic)
Background: In April of 2024, studies in the United States (US) identified the presence of influenza A(H5N1) viral RNA in 20%-40% of commercially available pasteurized milk in the US, suggesting that cattle ...

Joel Finney, etc.,al. Fluorescence-barcoded cell lines stably expressing membrane-anchored influenza neuraminidases. Vaccine, Vol 56, 22 May 2025, 127157.  Abstract  
submitted by kickingbird at Apr, 23, 2025 from Vaccine, Vol 56, 22 May 2025, 127157 (via https://www.sciencedirect.com/science/article/abs/pii/S02644)
The discovery of broadly protective antibodies to the influenza virus neuraminidase (NA) has raised interest in NA as a vaccine target. However, recombinant, solubilized tetrameric NA ectodomains are often ...

Anika John, etc.,al. [preprint]Wastewater sequencing reveals the genomic landscape of Influenza A virus in Switzerland. https://doi.org/10.1101/2025.04.17.25325990.  Abstract  
submitted by kickingbird at Apr, 23, 2025 from https://doi.org/10.1101/2025.04.17.25325990 (via https://www.medrxiv.org/content/10.1101/2025.04.17.25325990v)
Influenza A virus poses significant public health challenges, causing seasonal outbreaks and pandemics. Its rapid evolution motivates continuous monitoring of circulating influenza genomes to inform vaccine ...

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