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2026-2-1 15:48:49
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WHO. Influenza at the human-animal interface summary and assessment, 27 May 2025. WHO.  Abstract  
submitted by kickingbird at Jun, 4, 2025 from WHO (via https://www.who.int/publications/m/item/influenza-at-the-hum)
From 23 April to 27 May 2025, based on reporting date, the detection of influenza A(H5N1) in three humans, the detection of influenza A(H9N2) virus in eight humans and the detection of influenza A(H10N3) ...

Yang, J., Li, J., Sun, J. et al. Genetic diversity of H9N2 avian influenza viruses in poultry across China and implications for zoonotic transmission. Nat Microbiol (2025).  Abstract  
submitted by kickingbird at Jun, 3, 2025 from Nat Microbiol (2025) (via https://link.springer.com/article/10.1038/s41564-025-02002-x)
Nationwide surveillance of avian influenza viruses (AIVs) in live poultry markets across China has occurred since 2014, providing a resource for AIV prevalence and genetic diversity studies. Here we report ...

Nunn A, Sinilaite A, Warshawsky B, Salvadori MI, B. Avian influenza and use of the H5N1 vaccine to prevent zoonotic infection in Canada. CMAJ. 2025 Jun 1;197(21):E599-E600.  Abstract  
submitted by kickingbird at Jun, 3, 2025 from CMAJ. 2025 Jun 1;197(21):E599-E600 (via https://www.cmaj.ca/content/197/21/E599)
Key pointsOutbreaks of avian influenza A(H5N1) clade 2.3.4.4b viruses continue to be widespread among birds and poultry in many parts of the world, with transmission to mammals including humans in some ...

Mendoza LM, Anderson EM, Leonard AS, McFarland AG,. Antigenic Characterization of H1N1 Influenza Viruses That Circulated During the 2019-2020 Season in Philadelphia, Pennsylvania. Influenza Other Respir Viruses. 2025 Jun;19(6):e70.  Abstract  
submitted by kickingbird at Jun, 3, 2025 from Influenza Other Respir Viruses. 2025 Jun;19(6):e70 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70104)
Background: Multiple clades of H1N1 influenza A viruses (IAVs) circulated during the 2019-2020 season. Here, we completed serological assays to determine the specificities of serum antibodies from humans ...

Dharmayanti NLPI, Nurjanah D, Indriani R, Suyatno. Genomic surveillance of influenza A virus in live bird markets during the COVID-19 pandemic. Vet World. 2025 Apr;18(4):955-968.  Abstract  
submitted by kickingbird at Jun, 3, 2025 from Vet World. 2025 Apr;18(4):955-968 (via https://veterinaryworld.org/Vol.18/April-2025/20.php)
Background and aim: Despite the global focus on coronavirus disease 2019 (COVID-19), the avian influenza virus (AIV) continues to circulate in Indonesia, particularly in traditional live bird markets (LBMs), ...

Nacken, W., Mayr, J., Schreiber, A. et al. Influenza A virus NS1 suppresses nuclear speckles promoted gene expression by inhibition of transcription. npj Viruses 3, 46 (2025).  Abstract  
submitted by kickingbird at Jun, 2, 2025 from npj Viruses 3, 46 (2025) (via https://www.nature.com/articles/s44298-025-00124-x)
IAV-NS1 proteins that interact with Cleavage and polyadenylation specific factor 30 are known to inhibit host gene expression. Here we report that in both transfection and infection experiments, a strong ...

Lu, X., Zhao, S., Liu, A. et al. Nonlinear Enhanced Prediction of Influenza-Like Illness Using Seasonal-Trend Decomposition and Temporal Dependency. SIViP 19, 681 (2025).  Abstract  
submitted by kickingbird at Jun, 2, 2025 from SIViP 19, 681 (2025) (via https://link.springer.com/article/10.1007/s11760-025-04280-8)
Influenza-like illness (ILI) is a common respiratory infectious disease that puts significant strain on medical resources and leads to numerous fatalities worldwide. Accurate prediction of ILI incidence ...

Norikazu Isoda, etc.,al. Dynamics of high pathogenicity avian influenza virus infection with multiple introductions in a crow flock in an urban park in Hokkaido, Japan. Comparative Immunology, Microbiology and Infectiou.  Abstract  
submitted by kickingbird at Jun, 2, 2025 from Comparative Immunology, Microbiology and Infectiou (via https://www.sciencedirect.com/science/article/abs/pii/S01479)
Since 2021, high pathogenicity avian influenza viruses (HPAIVs) of the H5N1 clade 2.3.4.4b has been circulating globally, not only in domestic poultry but also in wild birds, both migratory and resident ...

Viviani L, Vecchio R, Pariani E, Sandri L, Binda S. Wastewater-based epidemiology of influenza viruses: a systematic review. Sci Total Environ. 2025 May 30;986:179706.  Abstract  
submitted by kickingbird at Jun, 1, 2025 from Sci Total Environ. 2025 May 30;986:179706 (via https://www.sciencedirect.com/science/article/pii/S004896972)
Introduction: Wastewater-based epidemiology (WBE) has emerged as a valuable public health tool for monitoring the circulation of many pathogens, including influenza viruses (IVs). The general aim of this ...

Martins-Filho PR, Quintans-Júnior LJ. Brazil´s First H5N1 Outbreak in Commercial Poultry: A Sentinel Event for Cross-Border Preparedness. J Travel Med. 2025 May 30:taaf050.  Abstract  
submitted by kickingbird at May, 31, 2025 from J Travel Med. 2025 May 30:taaf050 (via https://academic.oup.com/jtm/advance-article-abstract/doi/10)
Brazil's first confirmed H5N1 outbreak in commercial poultry marks a critical shift in South America's avian influenza landscape. The event calls for strengthened coordination between animal and human ...

Lombard J, Stenkamp-Strahm C, McCluskey B, Melody. Evidence of Viremia in Dairy Cows Naturally Infected with Influenza A Virus, California, USA. Emerg Infect Dis. 2025 Jul.  Abstract  
submitted by kickingbird at May, 31, 2025 from Emerg Infect Dis. 2025 Jul (via https://wwwnc.cdc.gov/eid/article/31/7/25-0134_article)
We confirmed influenza A virus (IAV) by PCR in serum from 18 cows on 3 affected dairy farms in California, USA. Our findings indicate the presence of viremia and might help explain IAV transmission dynamics ...

Qiong Zhang, etc.,al. [preprint]Preclinical Evaluation of an mRNA Vaccine Developed from the First Human Isolate of Bovine H5N1. https://doi.org/10.21203/rs.3.rs-6758243/v1.  Abstract  
submitted by kickingbird at May, 31, 2025 from https://doi.org/10.21203/rs.3.rs-6758243/v1 (via https://www.researchsquare.com/article/rs-6758243/v1)
Given the ongoing global health threat posed by the zoonotic emergence of H5N1 clade 2.3.4.4b highly pathogenic avian influenza (HPAI), there is an urgent need for the rapid development of effective vaccines. ...

Hassan M, Kaifer B, Christian T, Quaas XT, Mueller. First contact: an interdisciplinary guide into decoding H5N1 influenza virus interactions with glycosaminoglycans in 3D respiratory cell models. Front Cell Infect Microbiol. 2025 May 15;15:159695.  Abstract  
submitted by kickingbird at May, 30, 2025 from Front Cell Infect Microbiol. 2025 May 15;15:159695 (via https://www.frontiersin.org/journals/cellular-and-infection-)
The human respiratory system is vulnerable to viral infections. The influenza virus family alone accounts for one billion reported cases annually, some of which are severe and can be fatal. Among these, ...

Nabeshima, K., Asakura, S., Sakoda, Y. et al. Novel host factors associated with resistance to highly pathogenic avian influenza in wild birds inferred from primary cell culture. Sci Rep 15, 18809 (2025).  Abstract  
submitted by kickingbird at May, 30, 2025 from Sci Rep 15, 18809 (2025) (via https://www.nature.com/articles/s41598-025-01316-4)
Bird species differ in the sensitivity to the highly pathogenic avian influenza virus (HPAIV). Here, we infected fibroblasts from 11 bird species with the H5N1 HPAIV strain A/chicken/Yamaguchi/7/2004. ...

Cao L, Wang T, Ren P, Cheng C, Mao H, Hui X, Lin X. Viral polymerase-host interaction analysis reveals that the association between avian NUP93 and PB1 promotes H5N6 avian influenza virus replication. Microbiol Spectr 0:e03120-24.  Abstract  
submitted by kickingbird at May, 30, 2025 from Microbiol Spectr 0:e03120-24 (via https://journals.asm.org/doi/10.1128/spectrum.03120-24)
The H5N6 avian influenza virus, a highly pathogenic strain, poses a significant threat to poultry production and public health. The RNA-dependent RNA polymerase (comprising PB1, PB2, and PA proteins) and ...

Fahim, M., Alim, W., Abukamar, S. et al. Study of the effectiveness of a supported intervention package in reducing the risk of avian influenza human exposure through the reduction of infections in poultry: Egypt, 2006–2021. Virol J 22, 170 (2025).  Abstract  
submitted by kickingbird at May, 30, 2025 from Virol J 22, 170 (2025) (via https://link.springer.com/article/10.1186/s12985-025-02810-x)
IntroductionFor a decade, avian influenza (AI) viruses were major concern for Egypt since they are endemic in poultry and have caused 359 human infections, accounting for 40% of cases globally. Interventions ...

Cong He, etc.,al. A G219A hemagglutinin substitution increases pathogenicity and viral replication of Eurasian avian-like H1N1 swine influenza viruses. Veterinary Microbiology.  Abstract  
submitted by kickingbird at May, 30, 2025 from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
The Eurasian avian-like swine (EA) H1N1 virus has been widely prevalent in the Chinese swine population and has caused infections in human. However, knowledge regarding its pathogenic mechanisms remains ...

Seiler P, Kaplan BS, Brice DC, Duan S, Li L, McGar. Altered germinal center responses in mice vaccinated with highly pathogenic avian influenza A(H5N1) virus. Vaccine. 2025 May 27;60:127311.  Abstract  
submitted by kickingbird at May, 30, 2025 from Vaccine. 2025 May 27;60:127311 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Highly pathogenic avian influenza (HPAI) H5N1 virus vaccines typically yield lower neutralizing antibody titers in animals than influenza A virus (IAV) vaccines derived from other viral subtypes. To understand ...

Jenna Schafers, etc.,al. [preprint]Stability of influenza viruses in the milk of cows and sheep. https://doi.org/10.1101/2025.05.28.25328508.  Abstract  
submitted by kickingbird at May, 29, 2025 from https://doi.org/10.1101/2025.05.28.25328508 (via https://www.medrxiv.org/content/10.1101/2025.05.28.25328508v)
In late 2023, H5N1 high pathogenicity avian influenza (HPAIV) started circulating in dairy cattle in the USA. High viral titres were detected in milk from infected cows, raising concerns about onwards ...

Goldin, K., van Tol, S., Johnson, R.C. et al. Enhanced neurotropism of bovine H5N1 compared to the Vietnam H5N1 isolate in C57BL/6J mice. npj Viruses 3, 43 (2025).  Abstract  
submitted by kickingbird at May, 29, 2025 from npj Viruses 3, 43 (2025) (via https://www.nature.com/articles/s44298-025-00121-0)
In this study, we investigated differences in tissue tropism of two HPAI H5N1 strains, the isolate A/Vietnam/1203/2004 (VN1203) isolated from a fatal human case in 2004 and the bovine isolate A/Bovine/Ohio/B24osu-342/2024 ...

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