Antigua KJC, Baek YH, Choi WS, Jeong JH, Kim EH, O. Multiple HA substitutions in highly pathogenic avian influenza H5Nx viruses contributed to the change in the NA subtype preference. Virulence. 2022 Dec;13(1):990-1004. Abstract
submitted by kickingbird at Dec, 27, 2022 from Virulence. 2022 Dec;13(1):990-1004 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2022.2)
Novel highly pathogenic avian influenza (HPAI) H5Nx viruses are predominantly circulating worldwide, with an increasing potential threat of an outbreak in humans. It remains largely unknown how the stably ... Zhang J, Wang X, Ding S, Ma K, Jiang Y, Guo Y, Zha. Key amino acid position 272 in neuraminidase determines the replication and virulence of H5N6 avian influenza virus in mammals. iScience. 2022 Nov 30;25(12):105693. Abstract
submitted by kickingbird at Dec, 27, 2022 from iScience. 2022 Nov 30;25(12):105693 (via https://www.cell.com/iscience/fulltext/S2589-0042(22)01966-6)
Avian influenza H5N6 virus not only wreaks economic havoc in the poultry industry but also threatens human health. Strikingly, as of August 2022, 78 human beings were infected with H5N6, and the spike ... Yu C, Ding W, Zhu L, Zhou Y, Dong Y, Li L, Liu J,. Screening and characterization of inhibitory vNAR targeting nanodisc-assembled influenza M2 proteins. iScience. 2022 Dec 5;26(1):105736. Abstract
submitted by kickingbird at Dec, 27, 2022 from iScience. 2022 Dec 5;26(1):105736 (via https://www.cell.com/iscience/fulltext/S2589-0042(22)02009-0)
Influenza A virus poses a constant challenge to human health. The highly conserved influenza matrix-2 (M2) protein is an attractive target for the development of a universal antibody-based drug. However, ... Chang P, Lukosaityte D, Sealy JE, Rijal P, Sadeyen. Antigenic Characterization of Human Monoclonal Antibodies for Therapeutic Use against H7N9 Avian Influenza Virus. J Virol. 2022 Dec 21:e0143122. Abstract
submitted by kickingbird at Dec, 22, 2022 from J Virol. 2022 Dec 21:e0143122 (via https://journals.asm.org/doi/10.1128/jvi.01431-22)
Since 2013, H7N9 avian influenza viruses (AIVs) have caused more than 1,500 human infections and the culling of millions of poultry. Despite large-scale poultry vaccination, H7N9 AIVs continue to circulate ... Wang Q, Zeng X, Tan S, Lan L, Wang X, Lai Z, Liu Z. Pathogenicity and anti-infection immunity of animal H3N2 and H6N6 subtype influenza virus cross-species infection with tree shrews. Virus Res. 2022 Dec 18:199027. Abstract
submitted by kickingbird at Dec, 22, 2022 from Virus Res. 2022 Dec 18:199027 (via https://www.sciencedirect.com/science/article/pii/S016817022)
Animal influenza viruses can spread across species and pose a fatal threat to human health due to the high pathogenicity and mortality. Animal models are crucial for studying cross-species infection and ... Stadlbauer D, McMahon M, Turner HL, Zhu X, Wan H,. Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site. Nat Commun. 2022 Dec 21;13(1):7864. Abstract
submitted by kickingbird at Dec, 22, 2022 from Nat Commun. 2022 Dec 21;13(1):7864 (via https://www.nature.com/articles/s41467-022-35586-7)
Contemporary influenza A H3N2 viruses circulating since 2016 have acquired a glycosylation site in the neuraminidase in close proximity to the enzymatic active site. Here, we investigate if this S245N ... Guinat C, Valenzuela Agüí C, Vaughan TG, Scire J,. Disentangling the role of poultry farms and wild birds in the spread of highly pathogenic avian influenza virus in Europe. Virus Evol. 2022 Aug 18;8(2):veac073. Abstract
submitted by kickingbird at Dec, 21, 2022 from Virus Evol. 2022 Aug 18;8(2):veac073 (via https://academic.oup.com/ve/article/8/2/veac073/6671198)
In winter 2016-7, Europe was severely hit by an unprecedented epidemic of highly pathogenic avian influenza viruses (HPAIVs), causing a significant impact on animal health, wildlife conservation, and livestock ... Gaudino M, Chiapponi C, Moreno A, Zohari S, O&acut. Evolutionary and temporal dynamics of emerging influenza D virus in Europe (2009-22). Virus Evol. 2022 Sep 1;8(2):veac081. Abstract
submitted by kickingbird at Dec, 21, 2022 from Virus Evol. 2022 Sep 1;8(2):veac081 (via https://academic.oup.com/ve/article/8/2/veac081/6679728)
Influenza D virus (IDV) is an emerging influenza virus that was isolated for the first time in 2011 in the USA from swine with respiratory illness. Since then, IDV has been detected worldwide in different ... Gouma S, Furey C, Santos JJS, Parkhouse K, Weirick. Nucleoside-Modified mRNA-Based Influenza Vaccines Circumvent Problems Associated with H3N2 Vaccine Strain Egg Adaptation. J Virol. 2022 Dec 19:e0172322. Abstract
submitted by kickingbird at Dec, 21, 2022 from J Virol. 2022 Dec 19:e0172322 (via https://journals.asm.org/doi/10.1128/jvi.01723-22)
Most human influenza vaccine antigens are produced in fertilized chicken eggs. Recent H3N2 egg-based vaccine antigens have limited effectiveness, partially due to egg-adaptive substitutions that alter ... Chiba S, Hatta M, Pattinson D, Yasuhara A, Neumann. Ferret model to mimic the sequential exposure of humans to historical H3N2 influenza viruses. Vaccine. 2022 Dec 12:S0264-410X(22)01518-3. Abstract
submitted by kickingbird at Dec, 17, 2022 from Vaccine. 2022 Dec 12:S0264-410X(22)01518-3 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Mutations accumulate in influenza A virus proteins, especially in the main epitopes on the virus surface glycoprotein hemagglutinin (HA). For influenza A(H3N2) viruses, in particular, the antigenicity ... Noisumdaeng P, Phadungsombat J, Weerated S, Wiriya. Genetic evolution of hemagglutinin and neuraminidase genes of H5N1 highly pathogenic avian influenza viruses in Thailand. PeerJ. 2022 Nov 30;10:e14419. Abstract
submitted by kickingbird at Dec, 17, 2022 from PeerJ. 2022 Nov 30;10:e14419 (via https://peerj.com/articles/14419/)
Background: Ongoing outbreaks of H5N1 highly pathogenic avian influenza (HPAI) viruses and the emergence of the genetic-related hemagglutinin (HA) gene of reassortant H5Nx viruses currently circulating ... Zhang B, Huang W, Pei S, Zeng J, Shen W, Wang D, W. Mechanisms for the circulation of influenza A(H3N2) in China: A spatiotemporal modelling study. PLoS Pathog. 2022 Dec 16;18(12):e1011046.. Abstract
submitted by kickingbird at Dec, 17, 2022 from PLoS Pathog. 2022 Dec 16;18(12):e1011046. (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Circulation of seasonal influenza is the product of complex interplay among multiple drivers, yet characterizing the underlying mechanism remains challenging. Leveraging the diverse seasonality of A(H3N2) ... Marcenac P, McCarron M, Davis W, Igboh LS, Mott JA. Leveraging International Influenza Surveillance Systems and Programs during the COVID-19 Pandemic. Emerg Infect Dis. 2022;28(13):26-33. Abstract
submitted by kickingbird at Dec, 12, 2022 from Emerg Infect Dis. 2022;28(13):26-33 (via https://wwwnc.cdc.gov/eid/article/28/13/21-2248_article)
A network of global respiratory disease surveillance systems and partnerships has been built over decades as a direct response to the persistent threat of seasonal, zoonotic, and pandemic influenza. These ... Chen Y, Wang F, Yin L, Jiang H, Lu X, Bi Y, Zhang. Structural basis for a human broadly neutralizing influenza A hemagglutinin stem-specific antibody including H17/18 subtypes. Nat Commun. 2022 Dec 9;13(1):7603. Abstract
submitted by kickingbird at Dec, 11, 2022 from Nat Commun. 2022 Dec 9;13(1):7603 (via https://www.nature.com/articles/s41467-022-35236-y)
Influenza infection continues are a persistent threat to public health. The identification and characterization of human broadly neutralizing antibodies can facilitate the development of antibody drugs ... He J, Hou S, Xiong C, Hu L, Gong L, Yu J, Zhou X,. Avian influenza A virus H7N9 in China, a role reversal from reassortment receptor to the donator. J Med Virol. 2022 Dec 9. Abstract
submitted by kickingbird at Dec, 11, 2022 from J Med Virol. 2022 Dec 9 (via https://onlinelibrary.wiley.com/doi/10.1002/jmv.28392)
Reassortment can introduce one or more gene segments of influenza A viruses (IAVs) into another, resulting in novel subtypes. Since 2013, a new outbreak of human highly pathogenic avian influenza has emerged ... Kandeil A, Kayed A, Moatasim Y, Aboulhoda BE, El T. Molecular identification and virological characteristics of highly pathogenic avian influenza A/H5N5 virus in wild birds in Egypt. Microb Pathog. 2022 Dec 2:105928. Abstract
submitted by kickingbird at Dec, 8, 2022 from Microb Pathog. 2022 Dec 2:105928 (via https://www.sciencedirect.com/science/article/abs/pii/S08824)
Multiple incursions of different subtypes of highly pathogenic avian influenza (HPAI) A/H5NX viruses have caused widely considerable outbreaks in poultry and hundreds of human infections. Extensive reassortment ... Ng H, Li Y, Zhang T, Lu Y, Wong C, Ni J, Zhao Q. Association between multiple meteorological variables and seasonal influenza A and B virus transmission in Macau. Heliyon. 2022 Nov 24;8(11):e11820. Abstract
submitted by kickingbird at Dec, 5, 2022 from Heliyon. 2022 Nov 24;8(11):e11820 (via https://www.cell.com/heliyon/fulltext/S2405-8440(22)03108-5)
Few studies have evaluated the influence of meteorological variables on different influenza types in subtropical regions. This study aimed to explore the association between meteorological variables and ... Hiono T, Kobayashi D, Kobayashi A, Suzuki T, Satak. Virological, pathological, and glycovirological investigations of an Ezo red fox and a tanuki naturally infected with H5N1 high pathogenicity avian influenza viruses in Hokkaido, Japan. Virology. 2022 Nov 29;578:35-44. Abstract
submitted by kickingbird at Dec, 5, 2022 from Virology. 2022 Nov 29;578:35-44 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
In winter/spring 2021-2022, high pathogenicity avian influenza viruses (HPAIVs) that are genetically closely related to each other were detected worldwide. In a public garden in Sapporo, Hokkaido, Japan, ... Ivaturi K, Tsukhai V, Hassan WM. Influenza Type B Complicates a Previously Undiagnosed Case of Pericarditis. Cureus. 2022 Oct 28;14(10):e30810. Abstract
submitted by kickingbird at Dec, 4, 2022 from Cureus. 2022 Oct 28;14(10):e30810 (via https://www.cureus.com/articles/117490-influenza-type-b-comp)
We report the first case of pericarditis exacerbation due to influenza B viral infection while emphasizing the importance of cardiac magnetic resonance (CMR) for the timely diagnosis and ruling out of ... Ren W, Pei S, Jiang W, Zhao M, Jiang L, Liu H, Yi. A replication-deficient H9N2 influenza virus carrying H5 hemagglutinin conferred protection against H9N2 and H5N1 influenza viruses in mice. Front Microbiol. 2022 Nov 15;13:1042916. Abstract
submitted by kickingbird at Dec, 4, 2022 from Front Microbiol. 2022 Nov 15;13:1042916 (via https://www.frontiersin.org/articles/10.3389/fmicb.2022.1042)
H5N1 and H9N2 influenza viruses have been reported to cause human infections and are believed to have pandemic potential. The vaccine is an effective tool to prevent influenza virus infection. However, ... 7585 items, 20/Page, Page[44/380][|<<] [|<] [41] [42] [43] [44] [45] [46] [47] [48] [49] [50] [>|] [>>|] |
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