Haw DJ, Biggerstaff M, Prasad P, Walker J, Grenfel. Using real-time data to guide decision-making during an influenza pandemic: A modelling analysis. PLoS Comput Biol. 2023 Feb 27;19(2):e1010893. Abstract
submitted by kickingbird at Feb, 28, 2023 from PLoS Comput Biol. 2023 Feb 27;19(2):e1010893 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
Influenza pandemics typically occur in multiple waves of infection, often associated with initial emergence of a novel virus, followed (in temperate regions) by a resurgence accompanying the onset of the ... Li X, Xu Y, Li W, Che J, Zhao X, Cao R, Li X, Li S. Design, Synthesis, Biological Evaluation, and Molecular Dynamics Simulation of Influenza Polymerase PB2 Inhibitors. Molecules. 2023 Feb 15;28(4):1849. Abstract
submitted by kickingbird at Feb, 26, 2023 from Molecules. 2023 Feb 15;28(4):1849 (via https://www.mdpi.com/1420-3049/28/4/1849)
The PB2 subunit of the influenza RNA-dependent RNA polymerase (RdRp) has been identified as a promising target for the treatment of influenza. To expand the chemical space of the known influenza polymerase ... Ip HS, Uhm S, Killian ML, Torchetti MK. An Evaluation of Avian Influenza Virus Whole-Genome Sequencing Approaches Using Nanopore Technology. Microorganisms. 2023 Feb 19;11(2):529. Abstract
submitted by kickingbird at Feb, 26, 2023 from Microorganisms. 2023 Feb 19;11(2):529 (via https://www.mdpi.com/2076-2607/11/2/529)
As exemplified by the global response to the SARS-CoV-2 pandemic, whole-genome sequencing played an important role in monitoring the evolution of novel viral variants and provided guidance on potential ... Vreman S, Kik M, Germeraad E, Heutink R, Harders F. Zoonotic Mutation of Highly Pathogenic Avian Influenza H5N1 Virus Identified in the Brain of Multiple Wild Carnivore Species. Pathogens. 2023 Jan 20;12(2):168. Abstract
submitted by kickingbird at Feb, 26, 2023 from Pathogens. 2023 Jan 20;12(2):168 (via https://www.mdpi.com/2076-0817/12/2/168)
Wild carnivore species infected with highly pathogenic avian influenza (HPAI) virus subtype H5N1 during the 2021-2022 outbreak in the Netherlands included red fox (Vulpes vulpes), polecat (Mustela putorius), ... Chappell DE, Barnett DC, James K, Craig B, Bain F,. Voluntary Surveillance Program for Equine Influenza Virus in the United States during 2008-2021. Pathogens. 2023 Jan 27;12(2):192. Abstract
submitted by kickingbird at Feb, 26, 2023 from Pathogens. 2023 Jan 27;12(2):192 (via https://www.mdpi.com/2076-0817/12/2/192)
A voluntary upper respiratory biosurveillance program in the USA received 9740 nasal swab submissions during the years 2008-2021 from 333 veterinarians and veterinary clinics. The nasal swabs were submitted ... Tarasiuk K, Kycko A, ?wi?toń E, Bocian ?, Wyrostek. Homo- and Heterosubtypic Immunity to Low Pathogenic Avian Influenza Virus Mitigates the Clinical Outcome of Infection with Highly Pathogenic Avian Influenza H5N8 Clade 2.3.4.4.b in Captive Mallards (. Pathogens. 2023 Jan 30;12(2):217.. Abstract
submitted by kickingbird at Feb, 26, 2023 from Pathogens. 2023 Jan 30;12(2):217. (via https://www.mdpi.com/2076-0817/12/2/217)
In this study, we investigated the clinical response, viral shedding, transmissibility, pathologic lesions, and tropism of HPAIV Gs/Gd H5N8 subtype (clade 2.3.4.4b), following experimental infection of ... Sinnathamby MA, Warburton F, Reynolds AJ, Cottrell. An intercountry comparison of the impact of the paediatric live attenuated influenza vaccine (LAIV) programme across the UK and the Republic of Ireland (ROI), 2010 to 2017. Influenza Other Respir Viruses. 2023 Feb 13;17(2):. Abstract
submitted by kickingbird at Feb, 25, 2023 from Influenza Other Respir Viruses. 2023 Feb 13;17(2): (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13099)
Background: The universal paediatric live attenuated influenza vaccine (LAIV) programme commenced in the United Kingdom (UK) in 2013/2014. Since 2014/2015, all pre-school and primary school children in ... Braun KM, Haddock Iii LA, Crooks CM, Barry GL, Lal. Avian H7N9 influenza viruses are evolutionarily constrained by stochastic processes during replication and transmission in mammals. Virus Evol. 2023 Jan 19;9(1):vead004. Abstract
submitted by kickingbird at Feb, 24, 2023 from Virus Evol. 2023 Jan 19;9(1):vead004 (via https://academic.oup.com/ve/article/9/1/vead004/6991850)
H7N9 avian influenza viruses (AIVs) have caused over 1,500 documented human infections since emerging in 2013. Although wild-type H7N9 AIVs can be transmitted by respiratory droplets in ferrets, they have ... Nie J, Wang Q, Jin S, Yao X, Xu L, Chang Y, Ding F. Self-assembled multiepitope nanovaccine based on NoV P particles induces effective and lasting protection against H3N2 influenza virus. Nano Res. 2023 Feb 16:1-10. Abstract
submitted by kickingbird at Feb, 24, 2023 from Nano Res. 2023 Feb 16:1-10 (via https://link.springer.com/article/10.1007/s12274-023-5395-6)
Current seasonal influenza vaccines confer only limited coverage of virus strains due to the frequent genetic and antigenic variability of influenza virus (IV). Epitope vaccines that accurately target ... Aznar E, Casas I, González Praetorius A, Ruano Ram. Influenza A(H5N1) detection in two asymptomatic poultry farm workers in Spain, September to October 2022: suspected environmental contamination. Euro Surveill. 2023 Feb;28(8). Abstract
submitted by kickingbird at Feb, 24, 2023 from Euro Surveill. 2023 Feb;28(8) (via https://pubmed.ncbi.nlm.nih.gov/36820643/)
In autumn 2022, the Spanish Influenza National Reference Laboratory (NRL) confirmed the detection of influenza A(H5N1) in samples from two asymptomatic workers linked to an outbreak in a poultry farm in ... Gu M, Jiao J, Liu S, Zhao W, Ge Z, Cai K, Xu L, He. Monoclonal antibody targeting a novel linear epitope on nucleoprotein confers pan-reactivity to influenza A virus. Appl Microbiol Biotechnol. 2023 Feb 23:1–14.. Abstract
submitted by kickingbird at Feb, 24, 2023 from Appl Microbiol Biotechnol. 2023 Feb 23:1–14. (via https://link.springer.com/article/10.1007/s00253-023-12433-3)
Nucleoprotein (NP) functions crucially in the replicative cycle of influenza A virus (IAV) via forming the ribonucleoprotein complex together with PB2, PB1, and PA proteins. As its high conservation, NP ... McLean HQ, Petrie JG, Hanson KE, Meece JK, Rolfes. Interim Estimates of 2022-23 Seasonal Influenza Vaccine Effectiveness - Wisconsin, October 2022-February 2023. MMWR Morb Mortal Wkly Rep. 2023 Feb 24;72(8):201-2. Abstract
submitted by kickingbird at Feb, 24, 2023 from MMWR Morb Mortal Wkly Rep. 2023 Feb 24;72(8):201-2 (via https://www.cdc.gov/mmwr/volumes/72/wr/mm7208a1.htm?s_cid=mm)
In the United States, 2022-23 influenza activity began earlier than usual, increasing in October 2022, and has been associated with high rates of hospitalizations among children*. Influenza A(H3N2) represented ... Liu Y, Zeng Q, Hu X, Xu Z, Pan C, Liu Q, Yu J, Wu. Natural variant R246K in hemagglutinin increased zoonotic characteristics and renal inflammation in mice infected with H9N2 influenza virus. Vet Microbiol. 2023 Feb 3;279:109667. Abstract
submitted by kickingbird at Feb, 23, 2023 from Vet Microbiol. 2023 Feb 3;279:109667 (via https://www.sciencedirect.com/science/article/pii/S037811352)
Considered a potential pandemic candidate, the widespread among poultry of H9N2 avian influenza viruses across Asia and North Africa pose an increasing threat to poultry and human health. The massive epidemic ... Yin Y, Liu Y, Fen J, Liu K, Qin T, Chen S, Peng D,. Characterization of an H7N9 Influenza Virus Isolated from Camels in Inner Mongolia, China. Microbiol Spectr. 2023 Feb 21:e0179822. Abstract
submitted by kickingbird at Feb, 23, 2023 from Microbiol Spectr. 2023 Feb 21:e0179822 (via https://journals.asm.org/doi/10.1128/spectrum.01798-22)
The H7N9 subtype of influenza virus can infect birds and humans, causing great losses in the poultry industry and threatening public health worldwide. However, H7N9 infection in other mammals has not been ... Wang T, Zhang J, Wang Y, Li Y, Wang L, Yu Y, Yao Y. Influenza-trained mucosal-resident alveolar macrophages confer long-term antitumor immunity in the lungs. Nat Immunol. 2023 Feb 20. Abstract
submitted by kickingbird at Feb, 23, 2023 from Nat Immunol. 2023 Feb 20 (via https://www.nature.com/articles/s41590-023-01428-x)
Respiratory viral infections reprogram pulmonary macrophages with altered anti-infectious functions. However, the potential function of virus-trained macrophages in antitumor immunity in the lung, a preferential ... Nemoto M, Reedy SE, Yano T, Suzuki K, Fukuda S, Ga. Antigenic comparison of H3N8 equine influenza viruses belonging to Florida sublineage clade 1 between vaccine strains and North American strains isolated in 2021-2022. Arch Virol. 2023 Feb 19;168(3):94. Abstract
submitted by kickingbird at Feb, 23, 2023 from Arch Virol. 2023 Feb 19;168(3):94 (via https://pubmed.ncbi.nlm.nih.gov/36806782/)
Equine influenza virus strains of Florida sublineage clade 1 (Fc1) have been circulating in North America. In this study, virus neutralization assays were performed to evaluate antigenic differences between ... Zhang Y, Zhu T, Xu S, Gu P, Cai G, Peng S, Liu Z,. Cationic Nanoparticle-Stabilized Vaccine Delivery System for the H9N2 Vaccine to Promote Immune Response in Chickens. Mol Pharm. 2023 Feb 16. Abstract
submitted by kickingbird at Feb, 19, 2023 from Mol Pharm. 2023 Feb 16 (via https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.2c00805)
Chinese yam polysaccharides (CYPs) have received wide attention for their immunomodulatory activity. Our previous studies had discovered that the Chinese yam polysaccharide PLGA-stabilized Pickering emulsion ... Vatzia E, Feest K, McNee A, Manjegowda T, Carr BV,. Immunization with matrix-, nucleoprotein and neuraminidase protects against H3N2 influenza challenge in pH1N1 pre-exposed pigs. NPJ Vaccines. 2023 Feb 15;8(1):19. Abstract
submitted by kickingbird at Feb, 17, 2023 from NPJ Vaccines. 2023 Feb 15;8(1):19 (via https://pubmed.ncbi.nlm.nih.gov/36792640/)
There is an urgent need for influenza vaccines providing broader protection that may decrease the need for annual immunization of the human population. We investigated the efficacy of heterologous prime ... Chien YA, Alford BK, Wasik BR, Weichert WS, Parris. Single Particle Analysis of H3N2 Influenza Entry Differentiates the Impact of the Sialic Acids (Neu5Ac and Neu5Gc) on Virus Binding and Membrane Fusion. J Virol. 2023 Feb 13:e0146322. Abstract
submitted by kickingbird at Feb, 17, 2023 from J Virol. 2023 Feb 13:e0146322 (via https://journals.asm.org/doi/10.1128/jvi.01463-22)
Entry of influenza A viruses (IAVs) into host cells is initiated by binding to sialic acids (Sias), their primary host cell receptor, followed by endocytosis and membrane fusion to release the viral genome ... Yang L, Li G, Yang J, Zhang T, Du J, Liu T, Zhang. Deep-Learning Model for Influenza Prediction From Multisource Heterogeneous Data in a Megacity: Model Development and Evaluation. J Med Internet Res. 2023 Feb 13;25:e44238. Abstract
submitted by kickingbird at Feb, 17, 2023 from J Med Internet Res. 2023 Feb 13;25:e44238 (via https://www.jmir.org/2023/1/e44238)
Background: In megacities, there is an urgent need to establish more sensitive forecasting and early warning methods for acute respiratory infectious diseases. Existing prediction and early warning models ... 7583 items, 20/Page, Page[40/380][|<<] [|<] [31] [32] [33] [34] [35] [36] [37] [38] [39] [40] [>|] [>>|] |
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