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2026-6-11 2:35:50
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Jhaveri R. Live, Attenuated Influenza Vaccine: Is Past Performance a Guarantee of Future Results?. Clin Ther. 2018 Aug 6. pii: S0149-2918(18)30274-1..  Abstract  
submitted by kickingbird at Aug, 16, 2018 from Clin Ther. 2018 Aug 6. pii: S0149-2918(18)30274-1. (via https://www.ncbi.nlm.nih.gov/pubmed/30093132)
PURPOSE: Live, attenuated influenza vaccine (LAIV) has had a tumultuous recent history that can be difficult for many to follow and understand. This commentary reviews the origin of LAIV; the events and ...

Sano K, Ainai A, Suzuki T, Hasegawa H. Intranasal inactivated influenza vaccines for the prevention of seasonal influenza epidemics. Expert Rev Vaccines. 2018 Aug 9.  Abstract  
submitted by kickingbird at Aug, 16, 2018 from Expert Rev Vaccines. 2018 Aug 9 (via https://www.ncbi.nlm.nih.gov/pubmed/30092690)
Intranasal influenza vaccines are expected to confer protection among vaccine recipients by successful induction of mucosal immune response in the upper respiratory tract. Though only live attenuated influenza ...

Per Eriksson, etc.,al. Characterization of avian influenza virus attachment patterns to human and pig tissues. Scientific Reportsvolume 8, Article number: 12215.  Abstract  
submitted by kickingbird at Aug, 16, 2018 from Scientific Reportsvolume 8, Article number: 12215 (via https://www.nature.com/articles/s41598-018-29578-1)
Wild birds of Anseriformes and Charadriiformes are natural reservoirs of influenza A viruses (IAVs). Occasionally, IAVs transmit and adapt to mammalian hosts, and are maintained as epidemic strains in ...

Thompson MG, Pierse N, Sue Huang Q, Prasad N, et a. Influenza vaccine effectiveness in preventing influenza-associated intensive care admissions and attenuating severe disease among adults in New Zealand 2012-2015. Vaccine 2018 Aug 1. pii: S0264-410X(18)30997.  Abstract  
submitted by kickingbird at Aug, 13, 2018 from Vaccine 2018 Aug 1. pii: S0264-410X(18)30997 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30077480/)
BACKGROUND: Little is known about inactivated influenza vaccine effectiveness (IVE) in preventing very severe disease, including influenza-associated intensive care unit (ICU) admissions.METHODS: The Southern ...

Wu S, Pan Y, Zhang X, Zhang L, et al. Influenza vaccine effectiveness in preventing laboratory-confirmed influenza in outpatient settings: A test-negative case-control study in Beijing, China, 2016/17 season. Vaccine 2018 Aug 4. pii: S0264-410X(18)31097.  Abstract  
submitted by kickingbird at Aug, 13, 2018 from Vaccine 2018 Aug 4. pii: S0264-410X(18)31097 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30087046/)
BACKGROUND: The objective of this study was to estimate influenza vaccine effectiveness (VE) for the 2016/17 epidemic of co-circulating influenza A(H1N1)pdm09 and A(H3N2) viruses in Beijing, the capital ...

Shinjoh M, Sugaya N, Yamaguchi Y, Iibuchi N, et al. Inactivated influenza vaccine effectiveness and an analysis of repeated vaccination for children during the 2016/17 season. Vaccine 2018 Aug 6.  Abstract  
submitted by kickingbird at Aug, 13, 2018 from Vaccine 2018 Aug 6 (via https://www.ncbi.nlm.nih.gov/m/pubmed/30093289/)
OBJECTIVES: We assessed the vaccine effectiveness (VE) of inactivated influenza vaccine (IIV) in children 6?months to 15?years of age during the 2016/17 season. In addition, we estimated the impact of ...

Maier HE, Lopez R, Sanchez N, Ng S, et al. Obesity Increases the Duration of Influenza A Virus Shedding in Adults. J Infect Dis 2018 Aug 2..  Abstract  
submitted by kickingbird at Aug, 13, 2018 from J Infect Dis 2018 Aug 2. (via https://www.ncbi.nlm.nih.gov/m/pubmed/30085119/)
Epidemiologic studies indicate that obesity increases the risk of severe complications and death from influenza virus infections, especially in elderly individuals. This work investigates the effect of ...

Brodskaia AV, etc.,al. Inhibition of influenza A virus by mixed siRNAs, targeting the PA, NP, and NS genes, delivered by hybrid microcarriers. Antiviral Res. 2018 Aug 6. pii: S0166-3542(17)3073.  Abstract  
submitted by kickingbird at Aug, 11, 2018 from Antiviral Res. 2018 Aug 6. pii: S0166-3542(17)3073 (via https://www.ncbi.nlm.nih.gov/pubmed/30092251)
In the present study, a highly effective carrier system has been developed for the delivery of antiviral siRNA mixtures. The developed hybrid microcarriers, made of biodegradable polymers and SiO2 nanostructures, ...

Kuenstling TE, Sambol AR, Hinrichs SH. Oligomerization of bacterially expressed H1N1 recombinant hemagglutinin contributes to protection against viral challenge. Sci Rep. 2018 Aug 7;8(1):11856.  Abstract  
submitted by kickingbird at Aug, 11, 2018 from Sci Rep. 2018 Aug 7;8(1):11856 (via https://www.ncbi.nlm.nih.gov/pubmed/30087372)
Vaccination is the most effective intervention to prevent influenza and control the spread of the virus. Alternatives are needed to the traditional egg-based vaccine strategy for a more rapid response ...

Furusawa Y, Yamada S, Kawaoka Y. Host Factor Nucleoporin 93 Is Involved in the Nuclear Export of Influenza Virus RNA. Front Microbiol. 2018 Jul 24;9:1675.  Abstract  
submitted by kickingbird at Aug, 11, 2018 from Front Microbiol. 2018 Jul 24;9:1675 (via https://www.ncbi.nlm.nih.gov/pubmed/30087672)
Influenza virus replication relies on the functions of host factors. In our previous study, we identified host factors involved in virus replication and began analyses of their roles in this process. In ...

Fox A, Quinn KM, Subbarao K. Extending the Breadth of Influenza Vaccines: Status and Prospects for a Universal Vaccine. Drugs. 2018 Aug 7. doi: 10.1007/s40265-018-0958-7.  Abstract  
submitted by kickingbird at Aug, 11, 2018 from Drugs. 2018 Aug 7. doi: 10.1007/s40265-018-0958-7 (via https://www.ncbi.nlm.nih.gov/pubmed/30088204)
Despite the widespread use of seasonal influenza vaccines, there is urgent need for a universal influenza vaccine to provide broad, long-term protection. A number of factors underpin this urgency, including ...

Liang F, Guan P, Wu W, Liu J, Zhang N, Zhou B. A review of documents prepared by international organizations about influenza pandemics, including the 2009 pandemic: a bibliometric analysis. BMC Infect Dis. 2018 Aug 8;18(1):383.  Abstract  
submitted by kickingbird at Aug, 11, 2018 from BMC Infect Dis. 2018 Aug 8;18(1):383 (via https://www.ncbi.nlm.nih.gov/pubmed/30089459)
BACKGROUND: World Health Organization (WHO), the World Bank, UN System Influenza Coordination (UNSIC) and other international organizations released a series of documents to fight against the influenza ...

Du W, Dai M, Li Z, Boons GJ, Peeters B, van K. Substrate binding by the 2nd sialic acid-binding site of influenza A virus N1 neuraminidase contributes to enzymatic activity. J Virol. 2018 Aug 8..  Abstract  
submitted by kickingbird at Aug, 11, 2018 from J Virol. 2018 Aug 8. (via https://www.ncbi.nlm.nih.gov/pubmed/30089692)
The influenza A virus (IAV) neuraminidase (NA) protein plays an essential role in the release of virus particles from cells and decoy receptors. The NA enzymatic activity presumably needs to match the ...

Zhao M, etc.,al. Heterosubtypic Protections against Human-Infecting Avian Influenza Viruses Correlate to Biased Cross-T-Cell Responses. MBio. 2018 Aug 7;9(4)..  Abstract  
submitted by kickingbird at Aug, 11, 2018 from MBio. 2018 Aug 7;9(4). (via https://www.ncbi.nlm.nih.gov/pubmed/30087171)
Against a backdrop of seasonal influenza virus epidemics, emerging avian influenza viruses (AIVs) occasionally jump from birds to humans, posing a public health risk, especially with the recent sharp increase ...

Dickey T, Schweir M, Hysell M. Fatal Influenza B Myocarditis in a 34-Year-Old Female. Clin Pract Cases Emerg Med. 2018 May 29;2(3):219-2.  Abstract  
submitted by kickingbird at Aug, 11, 2018 from Clin Pract Cases Emerg Med. 2018 May 29;2(3):219-2 (via https://www.ncbi.nlm.nih.gov/pubmed/30083637)
A 34-year-old female reported to the emergency department with a chief complaint of epigastric pain. Initial rapid screening was negative for both influenza A and B. The patient eventually developed myocarditis ...

Lambertz RLO, Pippel J, Gerhauser I, Kollmus H. Exchange of amino acids in the H1-haemagglutinin to H3 residues is required for efficient influenza A virus replication and pathology in Tmprss2 knock-out mice. J Gen Virol. 2018 Aug 6..  Abstract  
submitted by kickingbird at Aug, 11, 2018 from J Gen Virol. 2018 Aug 6. (via https://www.ncbi.nlm.nih.gov/pubmed/30084768)
The haemagglutinin (HA) of H1N1 and H3N2 influenza A virus (IAV) subtypes has to be activated by host proteases. Previous studies showed that H1N1 virus cannot replicate efficiently in Tmprss2-/- knock-out ...

Epstein SL. Universal Influenza Vaccines: Progress in Achieving Broad Cross-Protection In Vivo. Am J Epidemiol. 2018 Aug 1..  Abstract  
submitted by kickingbird at Aug, 11, 2018 from Am J Epidemiol. 2018 Aug 1. (via https://www.ncbi.nlm.nih.gov/pubmed/30084906)
Despite all we have learned since 1918 about influenza virus and immunity, available influenza vaccines remain inadequate to control outbreaks of unexpected strains. Universal vaccines not requiring strain-matching ...

Loy H, Kuok DIT, Hui KPY, Choi MHL, Yuen W. Therapeutic implications of human umbilical cord mesenchymal stromal cells in attenuating influenza A/H5N1-associated acute lung injury. J Infect Dis. 2018 Aug 2..  Abstract  
submitted by kickingbird at Aug, 11, 2018 from J Infect Dis. 2018 Aug 2. (via https://www.ncbi.nlm.nih.gov/pubmed/30085072)
Background: Highly pathogenic avian influenza viruses can cause severe forms of acute lung injury (ALI) in humans, where pulmonary flooding leads to respiratory failure. Therapeutic benefits of bone-marrow ...

Song L, Xiong D, Hu M, Jiao X, Pan Z. Enhanced Th1/Th2 mixed immune responses elicited by polyethyleneimine adjuvanted influenza A (H7N9) antigen HA1-2 in chickens. Poult Sci. 2018 Aug 1.  Abstract  
submitted by kickingbird at Aug, 11, 2018 from Poult Sci. 2018 Aug 1 (via https://www.ncbi.nlm.nih.gov/pubmed/30085299)
Influenza A (H7N9) viruses have caused severe human infections and deaths every year in China since 2013. To reduce the risk of human infection and prevent a new influenza pandemic, there is a pressing ...

Grech-Angelini S, Hervé S, Rose N, Barbier N. Serological survey of influenza A viruses in domestic and wild Suidae in Corsica (France), a Mediterranean island environment.. Prev Vet Med. 2018 Sep 1;157:94-98..  Abstract  
submitted by kickingbird at Aug, 11, 2018 from Prev Vet Med. 2018 Sep 1;157:94-98. (via https://www.ncbi.nlm.nih.gov/pubmed/30086855)
Corsica is a mountainous French island in the north-western Mediterranean Sea. It is a rural area, where pig farming is a major economic activity. Although no acute respiratory outbreaks due to swine influenza ...

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