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2024-4-28 12:42:24
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Dittmann J, Stertz S, Grimm D, Steel J, García-Sas. Influenza A virus strains differ in sensitivity to the antiviral action of the Mx-GTPase. J Virol. 2008 Jan 16.  Abstract  
submitted by kickingbird at Jan, 23, 2008 from J Virol. 2008 Jan 16 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Interferon-mediated host responses are of great importance for controlling influenza A virus infections. It is well established that the interferon-induced Mx proteins possess powerful antiviral activities ...

Lam WY, Tang JW, Yeung AC, Chiu LC, Sung JJ, Chan. Avian influenza A/HK/483/97(H5N1) NS1 protein induces apoptosis in human airway epithelial cells. J Virol. 2008 Jan 16.  Abstract  
submitted by kickingbird at Jan, 23, 2008 from J Virol. 2008 Jan 16 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Avian H5N1 influenza virus causes a remarkably severe disease in humans, with an overall case-fatality rate of greater than 50%. Human influenza A viruses induce apoptosis in infected cells which can lead ...

Andreasen V, Viboud C, Simonsen L. Epidemiologic characterization of the 1918 influenza pandemic summer wave in copenhagen: implications for pandemic control strategies. J Infect Dis. 2008 Jan 15;197(2):270-8..  Abstract  
submitted by kickingbird at Jan, 23, 2008 from J Infect Dis. 2008 Jan 15;197(2):270-8. (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
The 1918-1919 A/H1N1 influenza pandemic killed 50 million people worldwide. Historical records suggest that an early pandemic wave struck Europe during the summer of 1918. Methods. @nbsp; We obtained surveillance ...

Lang AS, Kelly A, Runstadler JA. Prevalence and diversity of avian influenza viruses in environmental reservoirs. J Gen Virol. 2008 Feb;89(Pt 2):509-19.  Abstract  
submitted by kickingbird at Jan, 23, 2008 from J Gen Virol. 2008 Feb;89(Pt 2):509-19 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Little is known about the ecology and evolution of avian influenza in the natural environment, despite how these affect the potential for transmission. Most work has focused on characterizing viruses isolated ...

Jorba N, Area E, Ortín J. Oligomerization of the influenza virus polymerase complex in vivo. J Gen Virol. 2008 Feb;89(Pt 2):520-4.  Abstract  
submitted by kickingbird at Jan, 23, 2008 from J Gen Virol. 2008 Feb;89(Pt 2):520-4 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
The influenza virus polymerase is a heterotrimer formed by the PB1, PB2 and PA subunits and is responsible for virus transcription and replication. We have expressed the virus polymerase complex by co-transfection ...

YU H, Hua RH, Zhang Q, Liu TQ, et al.. Genetic evolution of swine influenza A (H3N2) viruses in China from 1970 to 2006. J Clin Microbiol. 2008 Jan 16.  Abstract  
submitted by kickingbird at Jan, 23, 2008 from J Clin Microbiol. 2008 Jan 16 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Pigs are susceptible to both human and avian influenza viruses and have been proposed to be intermediate hosts or "mixing vessels" for the generation of pandemic influenza viruses through reassortment ...

M. Giese et al.. Experimental Infection and Natural Contact Exposure of Dogs with Avian Influenza Virus (H5N1). Emerg Infect Dis. 2008 Feb.  Full Text  
submitted by kickingbird at Jan, 22, 2008 from Emerg Infect Dis. 2008 Feb (via http://www.cdc.gov/eid/content/14/2/pdfs/07-0864.pdf)
?Contact exposure experiments of influenza virus (H5N1)–infected cats with susceptible dogs, and   infected dogs with susceptible dogs and cats, did not result in intraspecies or interspecies transmission. ...

Parmley EJ, Bastien N, Booth TF, Bowes V, Buck PA,. Wild Bird Influenza Survey, Canada, 2005. Emerg Infect Dis. 2008 Jan.  Abstract  
submitted by kickingbird at Jan, 22, 2008 from Emerg Infect Dis. 2008 Jan (via http://www.cdc.gov/EID/content/14/1/84.htm)
AbstractOf 4,268 wild ducks sampled in Canada in 2005, real-time reverse transcriptase–PCR detected influenza A matrix protein (M1) gene sequence in 37% and H5 gene sequence in 5%. Mallards accounted for ...

WHO. Update on Avian Influenza A (H5N1) Virus Infection in Humans. NEJM.  Full Text  
submitted by kickingbird at Jan, 17, 2008 from NEJM (via http://content.nejm.org/cgi/content/full/358/3/261)
The unprecedented epizootic of avian influenza A (H5N1) viruses among birds continues to cause human disease with high mortality and to pose the threat of a pandemic. This review updates a 2005 report ...

Ngunjiri JM, Sekellick MJ, Marcus PI.. Clonogenic Assay of Type A Influenza Viruses Reveals Noninfectious Cell-Killing (Apoptosis-Inducing) Particlesa. J Virol. 2008 Jan 9.  Abstract  
submitted by kickingbird at Jan, 17, 2008 from J Virol. 2008 Jan 9 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Clonogenic (single-cell plating) assays were used to define and quantify subpopulations of two genetically closely related variants of influenza virus A/TK/OR/71 that differed primarily in the size of ...

Anwar T, Khan AU.. Identification of a casein kinase II phosphorylation domain in NS1 protein of H5N1 influenza virus.. Bioinformation. 2007 Oct 3;2(2):57-61.  Full Text  
submitted by kickingbird at Jan, 15, 2008 from Bioinformation. 2007 Oct 3;2(2):57-61 (via http://www.ncbi.nlm.nih.gov/pubmed/18188421?ordinalpos=1&ito)
Influenza virus causes febrile respiratory illness. The infection results in significant mortality, morbidity and economic disruption. In this bioinformatics study, we used the NS1 (the conserved nonstructural) ...

Liao YC, Lee MS, Ko CY, Hsiung CA.. Bioinformatics models for predicting antigenic variants of influenza A/H3N2 virus. Bioinformatics. 2008 Jan 10.  Abstract  
submitted by kickingbird at Jan, 15, 2008 from Bioinformatics. 2008 Jan 10 (via http://www.ncbi.nlm.nih.gov/pubmed/18187440?ordinalpos=3&ito)
MOTIVATION: Continual and accumulated mutations in hemagglutinin (HA) protein of influenza A virus generate novel antigenic strains that cause annual epidemics. RESULTS: We propose a model by incorporating ...

Ng SS, Li OT, Cheung TK, Peiris JM, Poon LL. Heterologous influenza vRNA segments with identical non-coding sequences stimulate viral RNA replication in trans. Virol J. 2008 Jan 11;5(1):2.  Abstract  
submitted by kickingbird at Jan, 15, 2008 from Virol J. 2008 Jan 11;5(1):2 (via http://www.ncbi.nlm.nih.gov/pubmed/18186945?ordinalpos=4&ito)
ABSTRACT: The initiation of transcription and replication of influenza A virus requires the 5' and 3' ends of vRNA. Here, the role of segment-specific non-coding sequences of influenza A virus on viral ...

Wang Q, Cheng F, Lu M, Tian X, Ma J.. Crystal Structure of Unliganded Influenza B Virus Hemagglutinin. J Virol. 2008 Jan 9.  Abstract  
submitted by kickingbird at Jan, 15, 2008 from J Virol. 2008 Jan 9 (via http://www.ncbi.nlm.nih.gov/pubmed/18184701?ordinalpos=10&it)
Here we report the crystal structure of hemagglutinin (HA) from influenza B/HK/8/73 virus determined to 2.8 A. At a sequence identity of approximately 25% to influenza A virus HAs, B/HK HA shares a similar ...

Djikeng A, Halpin RA, Kuzmickas R, Depasse J, Feld. Viral genome sequencing by random priming methods. BMC Genomics. 2008 Jan 7;9(1):5.  Full Text  
submitted by kickingbird at Jan, 11, 2008 from BMC Genomics. 2008 Jan 7;9(1):5 (via http://www.ncbi.nlm.nih.gov/pubmed/18179705?ordinalpos=10&it)
Most emerging health threats are of zoonotic origin. For the overwhelming majority, their causative agents are RNA viruses which include but are not limited to HIV, Influenza, SARS, Ebola, Dengue, and ...

Mazur I, Anhlan D, Mitzner D, Wixler L, Schubert U. The proapoptotic influenza A virus protein PB1-F2 regulates viral polymerase activity by interaction with the PB1 protein. Cell Microbiol. 2008 Jan 7.  Abstract  
submitted by kickingbird at Jan, 11, 2008 from Cell Microbiol. 2008 Jan 7 (via http://www.ncbi.nlm.nih.gov/pubmed/18182088?ordinalpos=4&ito)
The 11(th) influenza A virus protein PB1-F2 was previously shown to enhance apoptosis in response to cytotoxic stimuli. The 87 amino acid protein that is encoded by an alternative reading frame of the ...

Aarthi Chandrasekaran, etc.,al. Glycan topology determines human adaptation of avian H5N1 virus hemagglutinin. Nature Biotechnology 26, 107 - 113 (2007).  Abstract  
submitted by kickingbird at Jan, 9, 2008 from Nature Biotechnology 26, 107 - 113 (2007) (via http://www.nature.com/nbt/journal/v26/n1/abs/nbt1375.html)
A switch in specificity of avian influenza A viruses' hemagglutinin (HA) from avian-like (2-3 sialylated glycans) to human-like (2-6 sialylated glycans) receptors is believed to be associated with their ...

Shen CH, Ge Q, Talay O, Eisen HN, García-Sastre A,. Loss of IL-7R and IL-15R Expression Is Associated with Disappearance of Memory T Cells in Respiratory Tract following Influenza Infection. J Immunol. 2008 Jan 1;180(1):171-8.  Abstract  
submitted by kickingbird at Jan, 9, 2008 from J Immunol. 2008 Jan 1;180(1):171-8 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Following influenza virus infection, memory CD8 T cells are found in both lymphoid and nonlymphoid organs, where they exhibit striking differences in survival. We have assessed persistence, phenotype, ...

Zhou J, Matsuoka M, Cantor H, Homer R, Enelow RI.. Cutting Edge: Engagement of NKG2A on CD8+ Effector T Cells Limits Immunopathology in Influenza Pneumonia. J Immunol. 2008 Jan 1;180(1):25-9.  Abstract  
submitted by kickingbird at Jan, 9, 2008 from J Immunol. 2008 Jan 1;180(1):25-9 (via http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=Pub)
Influenza pneumonia results in considerable lung injury, a significant component of which is mediated by CD8(+) T cell Ag recognition in the distal airways and alveoli. TNF-alpha produced by Ag-specific ...

Itoh Y, Ozaki H, Tsuchiya H, Okamoto K, Torii R, S. A vaccine prepared from a non-pathogenic H5N1 avian influenza virus strain confers protective immunity against highly pathogenic avian influenza virus infection in cynomolgus macaques. Vaccine. 2007 Dec 3.  Abstract  
submitted by kickingbird at Jan, 7, 2008 from Vaccine. 2007 Dec 3 (via http://www.ncbi.nlm.nih.gov/pubmed/18164788?ordinalpos=25&it)
In order to prepare for the emergence of pandemic influenza viruses, we have established an influenza virus library that contains non-pathogenic influenza A virus strains with 135 combinations of 15 hemagglutinin ...

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