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2024-4-28 15:37:37
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Meisner J, Szretter KJ, Bradley KC, Langley WA, Li. Infectivity Studies of Influenza Virus Hemagglutinin Receptor Binding-Site Mutants in Mice. J Virol. 2008 Mar 19.  Abstract  
submitted by kickingbird at Mar, 25, 2008 from J Virol. 2008 Mar 19 (via http://jvi.asm.org/cgi/content/abstract/JVI.01958-07v1)
The replicative properties of influenza hemagglutinin (HA) mutants with altered receptor binding characteristics were analyzed following intranasal inoculation of mice. Among the mutants examined was a ...

Straight TM, Ottolini MG, Prince GA, Eichelberger. Antibody contributes to heterosubtypic protection against influenza A-induced tachypnea in cotton rats.. Virol J. 2008 Mar 20;5(1):44.  Abstract  
submitted by kickingbird at Mar, 25, 2008 from Virol J. 2008 Mar 20;5(1):44 (via http://www.virologyj.com/content/5/1/44)
 Influenza virus infection or vaccination evokes an antibody response to viral hemagglutinin (HA) and neuraminidase (NA) surface glycoproteins, which results in immunity against influenza A viruses ...

Nicas M, Best D.. A study quantifying the hand-to-face contact rate and its potential application to predicting respiratory tract infection.. J Occup Environ Hyg. 2008 Jun;5(6):347-52.  Abstract  
submitted by kickingbird at Mar, 25, 2008 from J Occup Environ Hyg. 2008 Jun;5(6):347-52 (via http://www.informaworld.com/smpp/content?content=10.1080/154)
A substantial portion of human respiratory tract infection is thought to be transmitted via contaminated hand contact with the mouth, eyes, and/or nostrils. Thus, a key risk factor for infection transmission ...

Wang J, Vijaykrishna D, Duan L, Bahl J, Zhang JX,. Identification of the progenitors of Indonesian and Vietnamese avian influenza A (H5N1) viruses from southern China. J Virol. 2008 Apr;82(7):3405-14.  Abstract  
submitted by kickingbird at Mar, 19, 2008 from J Virol. 2008 Apr;82(7):3405-14 (via http://www.ncbi.nlm.nih.gov/pubmed/18216109?ordinalpos=1)
The transmission of highly pathogenic avian influenza H5N1 virus to Southeast Asian countries triggered the first major outbreak and transmission wave in late 2003, accelerating the pandemic threat to ...

Roussan DA, Haddad R, Khawaldeh G.. Molecular survey of avian respiratory pathogens in commercial broiler chicken flocks with respiratory diseases in jordan. Poult Sci. 2008 Mar;87(3):444-8.  Abstract  
submitted by kickingbird at Mar, 19, 2008 from Poult Sci. 2008 Mar;87(3):444-8 (via http://www.ncbi.nlm.nih.gov/pubmed/18281569?dopt=Abstract)
Acute respiratory tract infections are of paramount importance in the poultry industry. Avian influenza virus (AIV), infectious bronchitis virus (IBV), Newcastle disease virus (NDV), avian pneumovirus ...

Raviv Y, Blumenthal R, Tompkins SM, Humberd J, Hog. Hydrophobic Inactivation of Influenza Viruses confers Preservation of Viral Structure with Enhanced Immunogenicity. J Virol. 2008 Feb 27.  Abstract  
submitted by kickingbird at Mar, 19, 2008 from J Virol. 2008 Feb 27 (via http://www.ncbi.nlm.nih.gov/pubmed/18305038?dopt=Abstract)
The use of inactivated influenza virus for the development of vaccines with broad heterosubtypic protection requires selective inactivation techniques that eliminate viral infectivity while preserving ...

Gabriel G, Herwig A, Klenk HD.. Interaction of Polymerase Subunit PB2 and NP with Importin alpha1 Is a Determinant of Host Range of Influenza A Virus. PLoS Pathog. 2008 Feb 1;4(2):e11.  Full Text  
submitted by kickingbird at Mar, 19, 2008 from PLoS Pathog. 2008 Feb 1;4(2):e11 (via http://www.plospathogens.org/article/info:doi/10.1371/journa)
We have previously reported that mutations in the polymerase proteins PB1, PB2, PA, and the nucleocapsid protein NP resulting in enhanced transcription and replication activities in mammalian cells are ...

Srinivasan A, Viswanathan K, Raman R, Chandrasekar. Quantitative biochemical rationale for differences in transmissibility of 1918 pandemic influenza A viruses. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2800-.  Full Text  
submitted by kickingbird at Mar, 19, 2008 from Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2800- (via http://www.pnas.org/cgi/content/full/105/8/2800)
The human adaptation of influenza A viruses is critically governed by the binding specificity of the viral surface hemagglutinin (HA) to long (chain length) alpha2-6 sialylated glycan (alpha2-6) receptors ...

Barr HL, Macfarlane JT, Macgregor O, Foxwell R, Bu. Ethical planning for an influenza pandemic. Clin Med. 2008 Feb;8(1):49-52..  Abstract  
submitted by kickingbird at Mar, 18, 2008 from Clin Med. 2008 Feb;8(1):49-52. (via http://www.ncbi.nlm.nih.gov/pubmed/18335669?ordinalpos=18&it)
A U.K. Pandemic Influenza Contingency Plan was developed in 2006 but little research has since been carried out as to how ethically acceptable it will be to society. A survey containing two hypothetical ...

Ciofi degli Atti ML, Merler S, Rizzo C, Ajelli M,. Mitigation measures for pandemic influenza in Italy: an individual based model considering different scenarios. PLoS ONE. 2008 Mar 12;3(3):e1790.  Full Text  
submitted by kickingbird at Mar, 18, 2008 from PLoS ONE. 2008 Mar 12;3(3):e1790 (via http://www.plosone.org/article/info:doi/10.1371/journal.pone)
BACKGROUND: Individual-based models can provide the most reliable estimates of the spread of infectious diseases. In the present study, we evaluated the diffusion of pandemic influenza in Italy and the ...

Jackson D, Hossain MJ, Hickman D, Perez DR, Lamb R. A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity. Proc Natl Acad Sci U S A. 2008 Mar 11.  Full Text  
submitted by kickingbird at Mar, 18, 2008 from Proc Natl Acad Sci U S A. 2008 Mar 11 (via http://www.pnas.org/cgi/reprint/0800482105v1)
The virulence of influenza virus is a multigenic trait. One determinant of virulence is the multifunctional NS1 protein that functions in several ways to defeat the cellular innate immune response. Recent ...

Vanlaere I, Vanderrijst A, Guénet JL, De Filette M. Mx1 causes resistance against influenza A viruses in the Mus spretus-derived inbred mouse strain SPRET/Ei. Cytokine. 2008 Mar 9.  Abstract  
submitted by kickingbird at Mar, 18, 2008 from Cytokine. 2008 Mar 9 (via http://www.ncbi.nlm.nih.gov/pubmed/18334301?ordinalpos=22&it)
Inbred SPRET/Ei mice, derived from Mus spretus, were found to be extremely resistant to infection with a mouse adapted influenza A virus. The resistance was strongly linked to distal chromosome 16, where ...

Halloran ME, Ferguson NM, Eubank S, Longini IM Jr,. Modeling targeted layered containment of an influenza pandemic in the United States. Proc Natl Acad Sci U S A. 2008 Mar 10.  Full Text  
submitted by kickingbird at Mar, 18, 2008 from Proc Natl Acad Sci U S A. 2008 Mar 10 (via http://www.pnas.org/cgi/reprint/0706849105v1)
Planning a response to an outbreak of a pandemic strain of influenza is a high public health priority. Three research groups using different individual-based, stochastic simulation models have examined ...

Busch MG, Bateman AC, Landolt GA, Karasin AI, Broc. Identification of amino acids in the HA of H3 influenza viruses that determine infectivity levels in primary swine respiratory epithelial cells. Virus Res. 2008 Mar 7.  Abstract  
submitted by kickingbird at Mar, 18, 2008 from Virus Res. 2008 Mar 7 (via http://www.ncbi.nlm.nih.gov/pubmed/18329747?ordinalpos=29&it)
In the late 1990s, triple reassortant H3N2 influenza A viruses emerged and spread widely within the swine population of the United States. We have shown previously that an isolate representative of this ...

Mancini DA, Alves RC, Mendon?a RM, Bellei NJ, Carr. Influenza virus and proteolytic bacteria co-infection in respiratory tract from individuals presenting respiratory manifestations. Rev Inst Med Trop Sao Paulo. 2008 Feb;50(1):41-46.  Abstract  
submitted by kickingbird at Mar, 18, 2008 from Rev Inst Med Trop Sao Paulo. 2008 Feb;50(1):41-46 (via http://www.ncbi.nlm.nih.gov/pubmed/18327486?ordinalpos=36&it)
A role for proteolytic bacteria in the exacerbation of influenza virus has been shown in natural hosts such as pigs and humans. Four hundred seven samples were collected from the respiratory tract of individuals ...

Wong TY, Koh GCh, Cheong SK, Lee HY, Fong YT, Sund. Concerns, Perceived Impact and Preparedness in an Avian Influenza Pandemic - a Comparative Study between Healthcare Workers in Primary and Tertiary Care. Ann Acad Med Singapore. 2008 Feb;37(2):96-7..  Abstract  
submitted by kickingbird at Mar, 18, 2008 from Ann Acad Med Singapore. 2008 Feb;37(2):96-7. (via http://www.ncbi.nlm.nih.gov/pubmed/18327343?ordinalpos=37&it)
Introduction: With the potential threat of an avian influenza (AI) pandemic, healthcare workers (HCWs) are expected to play important roles, and they encounter significant stress levels from an expected ...

Li WC, Shih SR, Huang YC, Chen GW, Chang SC, Hsiao. Clinical and genetic characterization of severe influenza B-associated diseases during an outbreak in Taiwan. J Clin Virol. 2008 Mar 4.  Abstract  
submitted by kickingbird at Mar, 18, 2008 from J Clin Virol. 2008 Mar 4 (via http://www.ncbi.nlm.nih.gov/pubmed/18325832?ordinalpos=39&it)
BACKGROUND: Mismatches between circulating and vaccine strains of influenza virus had been observed in Taiwan. A comprehensive clinical and genetic analysis of influenza B viruses-associated important ...

Long JX, Peng DX, Liu YL, Wu YT, Liu XF.. Virulence of H5N1 avian influenza virus enhanced by a 15-nucleotide deletion in the viral nonstructural gene. Virus Genes. 2008 Mar 4.  Abstract  
submitted by kickingbird at Mar, 9, 2008 from Virus Genes. 2008 Mar 4 (via http://www.ncbi.nlm.nih.gov/pubmed/18317917?ordinalpos=46&it)
More and more H5N1 subtype avian influenza viruses possessing a 15-nucleotide (15-nt) deletion in the viral nonstructural protein (NS) gene from position 263 to 277 have emerged since 2000. In order to ...

Nandi T.. Proposed lead molecules against Hemagglutinin of avian influenza virus (H5N1).. Bioinformation. 2008 Jan 27;2(6):240-4.  Abstract  
submitted by kickingbird at Mar, 9, 2008 from Bioinformation. 2008 Jan 27;2(6):240-4 (via http://www.ncbi.nlm.nih.gov/pubmed/18317572?ordinalpos=47&it)
Human infection with avian influenza H5N1 is an emerging infectious disease characterized by respiratory symptoms and a high fatality rate. Hemagglutinin and neuraminidase are the two surface proteins ...

Yamanaka T, Tsujimura K, Kondo T, Matsumura T.. Evaluation of antigen detection kits for diagnosis of equine influenza. J Vet Med Sci. 2008 Feb;70(2):189-92..  Abstract  
submitted by kickingbird at Mar, 9, 2008 from J Vet Med Sci. 2008 Feb;70(2):189-92. (via http://www.ncbi.nlm.nih.gov/pubmed/18319581?ordinalpos=37&it)
In this study, we evaluated whether five rapid antigen detection kits for human influenza could be used for the diagnosis of equine influenza (EI). Limiting dilution analyses showed that Directigen Flu ...

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