Shen W, Xu J, Chen Z, Wei Y, Wang Q, Wang X, Zhang. Broad-spectrum inhibition of influenza A virus replication by blocking the nuclear export of viral ribonucleoprotein complexes. J Virol 0:e01478-25. Abstract
submitted by kickingbird at 7 days ago from J Virol 0:e01478-25 (via https://journals.asm.org/doi/10.1128/jvi.01478-25)
Influenza A virus (IAV) remains a major threat to global health. The emergence of IAV strains resistant to commonly used anti-influenza medicines has made the need for novel broad-spectrum antiviral agents ... Cargnin Faccin, F., Gay, L.C., Regmi, D. et al. Sequential aerosol and oral immunization with a bivalent H9N2/H5N2 vaccine protects against H5N1 and H9N2 avian influenza challenges. npj Vaccines (2025). Abstract
submitted by kickingbird at 7 days ago from npj Vaccines (2025) (via https://link.springer.com/article/10.1038/s41541-025-01325-4)
Avian influenza continues to be a major threat to poultry and public health. This study investigated the efficacy of a bivalent H9N2/H5N2 modified live virus (MLV) vaccine delivered through a sequential ... Gopal AB, Lv H, Pholcharee T, Ouyang WO, Teo QW, L. Characterization of two non-competing antibodies to influenza H3N2 hemagglutinin stem reveals its evolving antigenicity. Nat Commun. 2025 Nov 26;16(1):10557. Abstract
submitted by kickingbird at 8 days ago from Nat Commun. 2025 Nov 26;16(1):10557 (via https://www.nature.com/articles/s41467-025-65595-1)
The conserved stem domain of influenza hemagglutinin (HA), which is classified into group 1 and group 2, is a target of broadly neutralizing antibodies. While many group 1 HA stem antibodies have been ... Shichinohe S, Hiono T, Itoh Y, Takada K, Kida Y, W. Characterization of H5N1 high pathogenicity avian influenza virus belonging to clade 2.3.4.4b isolated from Ezo red fox in Japan in a mouse model. Microbiol Spectr. 2025 Nov 26:e0109725. Abstract
submitted by kickingbird at 8 days ago from Microbiol Spectr. 2025 Nov 26:e0109725 (via https://journals.asm.org/doi/10.1128/spectrum.01097-25)
H5N1 high pathogenicity avian influenza virus (HPAIV) has spread in wild birds and poultry worldwide. H5N1 HPAIV belonging to the currently predominant clade 2.3.4.4b has infected not only birds but also ... ZHOU Yangzi, LIN Yukun, LI Xiyan, WANG Dayan, YAN. Epidemiological and Genetic Characterization of Canine Influenza Virus Outbreaks at a Dog Breeding Facility in Shangqiu, Henan Province, China, During the Winter of 2024-2025. CHINESE JOURNAL OF VIROLOGY (2025). Abstract
submitted by kickingbird at 8 days ago from CHINESE JOURNAL OF VIROLOGY (2025) (via http://www.flu.org.cn/scn/article_detail.asp?articleId=24526)
Two clusters of influenza?like illness (ILI) occurred during the winter of 2024-2025 at a dog breeding facility in Shangqiu, Henan Province, China. Clinical samples were collected and tested for influenza ... Gary, E.N., Tursi, N.J., Hojecki, C.E. et al. Electroporation and LNP-mediated delivery of plasmid DNA-encoded H5N1 influenza virus hemagglutinin support protection against highly pathogenic avian influenza. npj Vaccines (2025). Abstract
submitted by kickingbird at 9 days ago from npj Vaccines (2025) (via https://link.springer.com/article/10.1038/s41541-025-01316-5)
Highly pathogenic avian influenzas (HPAIs) is a continuing public health threat. Here, we describe the development of plasmid-encoded H5N1 hemagglutinin antigens representing clades that have caused human ... European Food Safety Authority, etc.,al. Unprecedented high level of highly pathogenic avian influenza in wild birds in Europe during the 2025 autumn migration. EFSA Journal. Abstract
submitted by kickingbird at 9 days ago from EFSA Journal (via https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2025)
Between 6 September and 14 November 2025, 1,443 highly pathogenic avian influenza (HPAI) A(H5) virus detections were reported in wild birds across 26 countries in Europe. This number was four times higher ... Hye-Ryoung Kim, etc.,al. Comparison of Gross Lesions in Poultry Naturally Infected With High Pathogenicity Avian Influenza H5N6 and H5N1 Viruses in South Korea, 2023-2025. Transboundary and Emerging Diseases. Abstract
submitted by kickingbird at 9 days ago from Transboundary and Emerging Diseases (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/1736453)
High pathogenicity avian influenza (HPAI) is an acute infectious disease of poultry and wild birds that has been occurring worldwide and has been controlled in many countries by culling birds on farms ... Larsen SV, Israelson R, Torp C, Larsen LE, Jensen. Transmission, Pathological and Clinical Manifestations of Highly Pathogenic Avian Influenza A Virus in Mammals with Emphasis on H5N1 Clade 2.3.4.4b. Viruses. 2025; 17(12):1548. Abstract
submitted by kickingbird at 9 days ago from Viruses. 2025; 17(12):1548 (via https://www.mdpi.com/1999-4915/17/12/1548)
Highly pathogenic avian influenza A virus (HPAIV) H5N1, clade 2.3.4.4b, has emerged as a significant zoonotic threat. H5N1 is widely circulating in wild birds, and an increasing number of spillover events ... Joel Armando Vazquez-Perez, etc.,al. [preprint]Emergence of a novel reassorted high pathogenicity avian influenza A(H5N2) virus associated with severe pneumonia in a young adult. https://doi.org/10.1101/2025.11.21.25340167. Abstract
submitted by kickingbird at 9 days ago from https://doi.org/10.1101/2025.11.21.25340167 (via https://www.medrxiv.org/content/10.1101/2025.11.21.25340167v)
Background Infection of backyard and poultry with low pathogenicity avian influenza LPAI A(H5N2) viruses has occurred in Mexico since 1994, and the first human infection caused by this influenza virus ... Zhang X, Lam SJ, Chen LL, Fong CH, Chan WM, Ip JD,. Avian influenza virus A(H5N1) genotype D1.1 is better adapted to human nasal and airway organoids than genotype B3.13. J Infect Dis. 2025 Nov 24:jiaf598. Abstract
submitted by kickingbird at 9 days ago from J Infect Dis. 2025 Nov 24:jiaf598 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
Three critically ill or fatal avian influenza A(H5N1) human infections have been reported in North America since November 2024. Notably, all were infected with genotype D1.1 instead of B3.13, the dominant ... Huang QJ, McDaniel CN, Griffith AA, Schiffer CA, S. Subnanometer-resolution Structural Determination of Hemagglutinin from Cryo-electron Tomography of Influenza Viruses. J Vis Exp. 2025 Nov 7;(225). Abstract
submitted by kickingbird at 9 days ago from J Vis Exp. 2025 Nov 7;(225) (via https://app.jove.com/t/68636/subnanometer-resolution-structu)
Cryo-electron tomography is a powerful tool to visualize heterogeneous samples, with one major application being structural characterization of pleomorphic viruses. In recent years, subtomogram averaging ... Chalkowski K, Miller RS, Chandler JC, Campos A, Ar. Elevated Exposure to Influenza A Viruses in Wild Pigs (Sus scrofa), Texas, USA. J Wildl Dis. 2025 Nov 25. Abstract
submitted by kickingbird at 9 days ago from J Wildl Dis. 2025 Nov 25 (via https://meridian.allenpress.com/jwd/article/doi/10.7589/JWD-)
Detections of highly pathogenic avian influenza viruses in mammals have increased globally, underscoring the need to assess influenza A virus (IAV) exposure in species that bridge wildlife, livestock, ... Kikawa C, Huddleston J, Loes AN, Turner SA, Lee J,. Near real-time data on the human neutralizing antibody landscape to influenza virus to inform vaccine-strain selection in September 2025. Virus Evol. 2025 Nov 3;11(1):veaf086. Abstract
submitted by kickingbird at 9 days ago from Virus Evol. 2025 Nov 3;11(1):veaf086 (via https://academic.oup.com/ve/article/11/1/veaf086/8313343)
The hemagglutinin of human influenza virus evolves rapidly to erode neutralizing antibody immunity. Twice per year, new vaccine strains are selected with the goal of providing maximum protection against ... EFSA. Avian influenza in Europe: enhanced surveillance and strict biosecurity needed as detections surge. EFSA. Abstract
submitted by kickingbird at 9 days ago from EFSA (via https://www.efsa.europa.eu/en/news/avian-influenza-europe-en)
Between 6 September and 14 November 2025, 1,443 detections of highly pathogenic avian influenza (HPAI) A(H5) viruses were reported in wild birds across 26 European countries – four times higher than the ... Tommy Tsan-Yuk Lam, Todd Davis. [preprint]Nomenclature updates to the hemagglutinin gene clade designations resulting from the continued evolution of high pathogenicity avian influenza A(H5) virus clades 2.3.2.1c and 2.3.4.4. https://doi.org/10.1101/2025.11.23.690055. Abstract
submitted by kickingbird at 10 days ago from https://doi.org/10.1101/2025.11.23.690055 (via https://www.biorxiv.org/content/10.1101/2025.11.23.690055v1)
The evolutionary divergence of the A(H5) hemagglutinin (HA) gene of high pathogenicity avian influenza (HPAI) viruses (A/goose/Guangdong/96 lineage) was analyzed by phylogenetic and average pairwise distance ... Moreno A, Pongolini S, Merialdi G, Cattoli G, Terr. Inactivation of Influenza A Viruses (H1N1, H5N1) During Grana-Type Raw Milk Cheesemaking: Implications for Foodborne Transmission Risk. Viruses. 2025; 17(12):1535. Abstract
submitted by kickingbird at 10 days ago from Viruses. 2025; 17(12):1535 (via https://www.mdpi.com/1999-4915/17/12/1535)
The detection of H5N1 highly pathogenic avian influenza virus (HPAIV) in lactating dairy cattle in the United States, with high viral titers in raw milk, has raised concerns about zoonotic transmission ... Li Z, Liu M, Yang J, Sun Q, Ye D, Zhou W, Du R, Ch. Generation and Characterization of a CE1-Modified mCherry-Expressing Influenza A Virus for In Vivo Imaging and Antiviral Drug Evaluation. Viruses. 2025; 17(12):1537. Abstract
submitted by kickingbird at 10 days ago from Viruses. 2025; 17(12):1537 (via https://www.mdpi.com/1999-4915/17/12/1537)
Influenza reporter viruses are essential for studying viral infection dynamics and assessing antiviral drug efficacy. However, insertion of exogenous reporter genes can impair both viral replication and ... Pérez-Sánchez T, Báez JC, Johnstone C. Concern for Highly Pathogenic Avian Influenza Spillover into Cetaceans. Viruses. 2025; 17(12):1536. Abstract
submitted by kickingbird at 10 days ago from Viruses. 2025; 17(12):1536 (via https://www.mdpi.com/1999-4915/17/12/1536)
Influenza A virus (IAV) has a wide range of avian and mammalian hosts, leading to disease outbreaks and increasing the risk of panzootics and pandemics. Subtype H5N1 of clade 2.3.4.4b is causing the current ... Majumdar, D., Hann, E., Short, K.R. et al. Genetic strategies for avian influenza resilience in poultry: from host-pathogen interaction studies to precision breeding. Funct Integr Genomics 25, 252 (2025). Abstract
submitted by kickingbird at 10 days ago from Funct Integr Genomics 25, 252 (2025) (via https://link.springer.com/article/10.1007/s10142-025-01777-w)
Avian influenza virus (AIV) remains a persistent threat to global poultry production and public health, owing to its ability to infect a wide range of avian and mammalian species. The global resurgence ... 9542 items, 20/Page, Page[3/478][|<<] [|<] [1] [2] [3] [4] [5] [6] [7] [8] [9] [10] [>|] [>>|] |
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