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2026-6-10 16:56:06
Article

Hoang-Hai Nguyen, etc.,al. [preprint]Interpreting the WaveSeekerNet model to reveal the evolution and biology of influenza A virus. https://doi.org/10.64898/2026.05.23.726879.  Abstract  
submitted by kickingbird at 13 days ago from https://doi.org/10.64898/2026.05.23.726879 (via https://www.biorxiv.org/content/10.64898/2026.05.23.726879v1)
Background Influenza A virus (IAV) is a major public health burden, causing seasonal epidemics and occasional pandemics. Its transmission from avian species to mammals and subsequent spread requires adaptive ...

Paloma A. Encinas, etc.,al. [preprint]Zoonotic infections and genomic evolution of novel reassortant swine influenza A viruses in Spain. https://doi.org/10.64898/2026.05.22.724525.  Abstract  
submitted by kickingbird at 13 days ago from https://doi.org/10.64898/2026.05.22.724525 (via https://www.biorxiv.org/content/10.64898/2026.05.22.724525v1)
Influenza A virus (IAV) circulates widely in European pig populations and continues to diversify through frequent introductions from humans, followed by reassortment within swine. Spain represents a particularly ...

Huang, J., Sun, Q., Zhong, Y. et al. T-cell-mediated immunity to influenza A (H2N3): implications for caccine efficacy and cross-subtype protection. Arch Microbiol 208, 404 (2026).  Abstract  
submitted by kickingbird at 13 days ago from Arch Microbiol 208, 404 (2026) (via https://link.springer.com/article/10.1007/s00203-026-04928-0)
Influenza A viruses pose a significant pandemic threat, with H2N3 in particular representing a subtype of particular concern due to limited population immunity and potential for zoonotic transmission. ...

Taboada B, Zárate S, Mu?oz-Medina JE, Vazquez-Pere. Post-Pandemic Genomic Diversity and Lineage Turnover of Influenza Viruses in Mexico During 2022–2023. Viruses. 2026; 18(6):609.  Abstract  
submitted by kickingbird at 13 days ago from Viruses. 2026; 18(6):609 (via https://www.mdpi.com/1999-4915/18/6/609)
Seasonal influenza circulation was profoundly disrupted during the COVID-19 pandemic, resulting in an unprecedented global decline in viral activity and genetic diversity. As non-pharmaceutical interventions ...

Hou Z, Wang H, Zhang B, Liu R, Zhang Y, Yang Y, Wu. Aerosol Inhalation of a Recombinant H7N9 Hemagglutinin Antigen Elicits Systemic and Mucosal Immune Responses in Mice. Viruses. 2026 May 21;18(5):579.  Abstract  
submitted by kickingbird at 13 days ago from Viruses. 2026 May 21;18(5):579 (via https://www.mdpi.com/1999-4915/18/5/579)
Highly pathogenic avian influenza A (H7N9) remains a threat to poultry health and poses a zoonotic risk, highlighting the need for vaccine antigens capable of inducing both systemic and mucosal immunity. ...

Zhang Y, Qin C, Zhuang Y, Chen L, Zeng X, Jiang L,. USP17L13 Enhances Influenza a Virus Replication by Mediating the Degradation of RIG-I and MDA5. Viruses. 2026 May 20;18(5):575.  Abstract  
submitted by kickingbird at 13 days ago from Viruses. 2026 May 20;18(5):575 (via https://www.mdpi.com/1999-4915/18/5/575)
The innate immune system, particularly the retinoic acid-inducible gene I (RIG-I)-like receptor (RLR) signaling pathway, is a major early defense barrier against influenza A virus infection. However, excessive ...

Loes AN, Tarabi RAL, Li SH, Atkinson RK, Huddlesto. Strain-specific differences in the response to egg-derived versus recombinant protein influenza vaccines. J Virol. 2026 May 27:e0031726.  Abstract  
submitted by kickingbird at 13 days ago from J Virol. 2026 May 27:e0031726 (via https://journals.asm.org/doi/10.1128/jvi.00317-26)
The 2023/2024 influenza vaccine included an updated H1N1 component designed to better match a new clade of H1N1 that had multiple mutations in antigenic epitopes of hemagglutinin. Despite this update, ...

Liu, Y., Fu, X., Wang, Y., Jia, L., Xu, L., Li, R.. Evaluation of influenza vaccine effectiveness among older adults in Jiaxing, China, 2022-2025: A test negative design-based study. Human Vaccines & Immunotherapeutics, 22(1).  Abstract  
submitted by kickingbird at 13 days ago from Human Vaccines & Immunotherapeutics, 22(1) (via https://www.tandfonline.com/doi/full/10.1080/21645515.2026.2)
Influenza imposes a substantial burden on older adults, underscoring the need for annual evaluation of vaccine effectiveness (VE). Using a test-negative case-control design, this study assessed VE among ...

European Food Safety Authority (EFSA), Miguel Melo. Deriving species-specific relative weights for wild birds in a spatio-temporal risk model of HPAI in Europe. EFSA.  Abstract  
submitted by kickingbird at 14 days ago from EFSA (via https://efsa.onlinelibrary.wiley.com/doi/10.2903/sp.efsa.202)
This report describes the derivation of species-specific relative weights for 25 wild bird species evaluated for inclusion in the Bird Flu Radar, a spatio-temporal risk assessment tool developed by the ...

Hannah L Wallace, etc.,al. [preprint]Detection of Anti-H5 Antibodies in People with Exposure to Wild Birds in Northern Canada. https://doi.org/10.64898/2026.05.24.26353994.  Abstract  
submitted by kickingbird at 14 days ago from https://doi.org/10.64898/2026.05.24.26353994 (via https://www.medrxiv.org/content/10.64898/2026.05.24.26353994)
Using a commercially available H5 serology assay, we identified a 7.4% (n=5/68) anti-H5 seroreactivity rate among hunters in Northern Canada. All participants reported close contact with wild birds.

Ross A. Edwards, etc.,al. [preprint]The Q226H Mutation in Avian H5N1 Hemagglutinin Mediates a Path towards Structural Adaptation in Humans. https://doi.org/10.64898/2026.05.21.726965.  Abstract  
submitted by kickingbird at 14 days ago from https://doi.org/10.64898/2026.05.21.726965 (via https://www.biorxiv.org/content/10.64898/2026.05.21.726965v1)
The global outbreak of highly pathogenic avian influenza (HPAI) A(H5N1) among birds and the spillover to mammals increases the risk for humans. A recent case in British Columbia with a clade 2.3.4.4b H5 ...

Rang Wang, etc.,al. Genetic determinants of cell- and egg-preferred replication in H3N2 canine influenza virus. Veterinary Microbiology.  Abstract  
submitted by kickingbird at 14 days ago from Veterinary Microbiology (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
The H3N2 canine influenza virus (CIV), which originated from avian influenza viruses and has circulated in dogs for over two decades, remains poorly understood in terms of its host adaptation mechanisms ...

Heidi Liu, etc.,al. Strain-specific responses of avian influenza virus to disruption of solute carrier family 35 member A1 (SLC35A1) in chicken cells. Poultry Science.  Abstract  
submitted by kickingbird at 14 days ago from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian influenza virus (AIV) poses a persistent threat to poultry health and food security, with conventional control measures offering limited protection. A promising alternative is the use of gene editing ...

Vuokko H?rm?, etc.,al. Lessons from the 2024 avian influenza vaccination campaign in Finland: a qualitative inquiry. Vaccine.  Abstract  
submitted by kickingbird at 15 days ago from Vaccine (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Highly pathogenicity avian influenza H5N1 (HPAI H5N1) viruses cause a continuous threat to wild avian populations. During recent years, spillover to both wild and domestic mammals has occurred with an ...

Gomaa MR, Yazbek J, et al. Spill-Over of Avian and Human Influenza a Viruses to Swine in Egypt and Lebanon. Zoonotic Diseases. 2026; 6(2):21.  Abstract  
submitted by kickingbird at 15 days ago from Zoonotic Diseases. 2026; 6(2):21 (via https://www.mdpi.com/2813-0227/6/2/21)
Influenza A viruses circulate between birds, humans, and pigs, creating opportunities for the emergence of new strains with potential public health impact. In avian influenza (AI)-endemic countries such ...

Zhang Y, Bai X, Nie C, et al. Clade 2.3.4.4b H5N1 HPAIV from Migratory Birds in Beidaihe Wetland, North China. Viruses. 2026; 18(6):595.  Abstract  
submitted by kickingbird at 15 days ago from Viruses. 2026; 18(6):595 (via https://www.mdpi.com/1999-4915/18/6/595)
During 2022–2024, a highly pathogenic avian influenza virus (HPAIV) H5N1 strain, designated A/Seagull/Hebei/qhd6/2024 (H5N1), was isolated from migratory birds in Beidaihe National Wetland Park, North ...

Vanstreels RET, Serafini PP, Giacinti J, Younger J. A public database to monitor the spread and impacts of high pathogenicity avian influenza viruses on albatrosses and petrels. Biodivers Data J. 2026 May 15;14:e186836.  Abstract  
submitted by kickingbird at 15 days ago from Biodivers Data J. 2026 May 15;14:e186836 (via https://bdj.pensoft.net/article/186836/)
Background: High pathogenicity avian influenza (HPAI) viruses have rapidly emerged as a major global threat to wildlife, with severe consequences for seabird populations. Albatrosses and petrels (order ...

Brian Root, etc.,al. [preprint]Predicting Influenza Virus Host Tropism and Zoonotic Spillover Risk from Protein Sequences. https://doi.org/10.64898/2026.05.21.726772.  Abstract  
submitted by kickingbird at 15 days ago from https://doi.org/10.64898/2026.05.21.726772 (via https://www.biorxiv.org/content/10.64898/2026.05.21.726772v1)
Novel infectious diseases, predominantly originating from non-human animals, pose a significant threat to global public health and economic stability. Avian influenza virus presents an especially significant ...

Pablo Puchades-Colera etc.,al. Methods for detecting highly pathogenic avian influenza H5N1 virus in dairy processing environments. Front. Microbiol..  Abstract  
submitted by kickingbird at May, 25, 2026 from Front. Microbiol. (via https://www.frontiersin.org/journals/microbiology/articles/1)
The spread of highly pathogenic avian influenza (HPAI) H5N1 into mammals, including U.S. dairy cattle, underscores the need for effective surveillance in milk and environmental samples. This study evaluated ...

Kieran Dee, etc.,al. [preprint]Understanding the emergence of the influenza A/H3N2 K subclade in its historical and evolutionary context. https://doi.org/10.64898/2026.05.21.726823.  Abstract  
submitted by kickingbird at May, 25, 2026 from https://doi.org/10.64898/2026.05.21.726823 (via https://www.biorxiv.org/content/10.64898/2026.05.21.726823v1)
The emergence in 2025/26 of the influenza A/H3N2 K substrain (H3N2/K) was the cause of significant public health concern. This genetically divergent virus was assessed to have a strongly decreased reactivity ...

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