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2024-4-25 15:01:43
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Yu HJ, etc.,al. Human infection with avian influenza A H7N9 virus: an assessment of clinical severity. The Lancet, Early Online Publication, 24 June 2013.  Abstract  
submitted by kickingbird at Jun, 27, 2013 from The Lancet, Early Online Publication, 24 June 2013 (via http://www.lancet.com/journals/lancet/article/PIIS0140-6736()
Background Characterisation of the severity profile of human infections with influenza viruses of animal origin is a part of pandemic risk assessment, and an important part of the assessment of disease ...

YF Zhu, etc.,al. Human co-infection with novel avian influenza A H7N9 and influenza A H3N2 viruses in Jiangsu province, China. The Lancet, Volume 381, Issue 9883,.  Abstract  
submitted by kickingbird at Jun, 16, 2013 from The Lancet, Volume 381, Issue 9883, (via http://www.thelancet.com/journals/lancet/article/PIIS0140-67)
In February, 2013, a novel avian influenza A H7N9 virus emerged in east China and quickly spread to other areas. 1—3 By May 27, 130 human infections had been confirmed, with 37 deaths. Transmission can ...

Janet E McElhaney, etc.,al. AS03-adjuvanted versus non-adjuvanted inactivated trivalent influenza vaccine against seasonal influenza in elderly people: a phase 3 randomised trial. The Lancet Infectious Diseases, Volume 13, Issue 6.  Abstract  
submitted by kickingbird at Jun, 16, 2013 from The Lancet Infectious Diseases, Volume 13, Issue 6 (via http://www.thelancet.com/journals/laninf/article/PIIS1473-30)
Background We aimed to compare AS03-adjuvanted inactivated trivalent influenza vaccine (TIV) with non-adjuvanted TIV for seasonal influenza prevention in elderly people. ...

JANG YH, Jung EJ, Byun YH, Lee KH, et al. Immunogenicity and protective efficacy of cold-adapted X-31 live attenuated pre-pandemic H5N1 influenza vaccines. Vaccine. 2013 Jun 3..  Abstract  
submitted by kickingbird at Jun, 16, 2013 from Vaccine. 2013 Jun 3. (via http://www.ncbi.nlm.nih.gov/pubmed/23742997)
Despite global efforts to control influenza viruses, they have taken a heavy toll on human public health worldwide. Among particular threats is highly pathogenic avian H5N1 influenza virus (HPAI) due to ...

SEGURA-VELAZQUEZ R, Cervantes J, Acosta E, Sanchez. Influenza vaccine: Development of a novel intranasal and subcutaneous recombinant adjuvant. Vaccine. 2013 Jun 4.  Abstract  
submitted by kickingbird at Jun, 16, 2013 from Vaccine. 2013 Jun 4 (via http://www.ncbi.nlm.nih.gov/pubmed/23746458)
The synthetic peptide GK-1, derived from Taenia crassiceps, enhances the protection induced by human influenza vaccine in both young and aged mice. Herein, the adjuvant properties of GK-1 fused to the ...

Centers for Disease Control and Prevention (CDC).. Influenza activity - United States, 2012-13 season and composition of the 2013-14 influenza vaccine. MMWR. 2013 Jun 14;62(23):473-9.  Abstract  
submitted by kickingbird at Jun, 16, 2013 from MMWR. 2013 Jun 14;62(23):473-9 (via http://www.ncbi.nlm.nih.gov/pubmed/23760189)
During the 2012-13 influenza season in the United States, influenza activity* increased through November and December before peaking in late December. Influenza A (H3N2) viruses predominated overall, but ...

KAPCZYNSKI DR, Pantin-Jackwood M, Guzman SG, Ricar. Characterization of the 2012 Highly Pathogenic Avian Influenza H7N3 virus isolated from poultry in an outbreak in Mexico: Pathobiology and Vaccine Protection. J Virol. 2013 Jun 12..  Abstract  
submitted by kickingbird at Jun, 16, 2013 from J Virol. 2013 Jun 12. (via http://www.ncbi.nlm.nih.gov/pubmed/23760232)
In June of 2012, a H7N3 highly pathogenic avian influenza (HPAI) virus was identified as the cause of a severe disease outbreak in commercial laying chicken farms in Mexico. The purpose of this study was ...

LU X, Qi J, Shi Y, Wang M, et al. Structure and receptor binding specificity of the hemagglutinin H13 from avian influenza A virus H13N6. J Virol. 2013 Jun 12.  Abstract  
submitted by kickingbird at Jun, 16, 2013 from J Virol. 2013 Jun 12 (via http://www.ncbi.nlm.nih.gov/pubmed/23760233)
Interspecies transmission or host switch/jump of influenza viruses is a key scientific question that must be addressed. In addition to the vigorous research on highly pathogenic avian influenza viruses ...

AEFFNER F, Abdulrahman B, Hickman-Davis JM, Jansse. Heterozygosity for the F508del mutation in the cystic fibrosis transmembrane conductance regulator anion channel attenuates influenza severity. J Infect Dis. 2013 Jun 7..  Abstract  
submitted by kickingbird at Jun, 16, 2013 from J Infect Dis. 2013 Jun 7. (via http://www.ncbi.nlm.nih.gov/pubmed/23749967)
Background.?Seasonal and pandemic influenza are significant public health concerns. Influenza stimulates respiratory epithelial Cl- secretion via the cystic fibrosis transmembrane conductance regulator ...

VIASUS D, Marinescu C, Villoslada A, Cordero E, et. Community-acquired pneumonia during the first post-pandemic influenza season: A prospective, multicentre cohort (postp10-11) study from Spain. J Infect. 2013 Jun 6.  Abstract  
submitted by kickingbird at Jun, 16, 2013 from J Infect. 2013 Jun 6 (via http://www.ncbi.nlm.nih.gov/pubmed/23747416)
OBJECTIVES:  To determine the aetiology, clinical features and prognosis of CAP during the first post-pandemic influenza season. We also assessed the factors associated with severe disease and tested the ability of a scoring system for identifying influenza A (H1N1)pdm09-related pneumonia. ...

THARAKARAMAN K, Jayaraman A, Raman R, Viswanathan. Glycan Receptor Binding of the Influenza A Virus H7N9 Hemagglutinin. Cell. 2013 Jun 4. pii: S0092-8674(.  Abstract  
submitted by kickingbird at Jun, 16, 2013 from Cell. 2013 Jun 4. pii: S0092-8674( (via http://www.ncbi.nlm.nih.gov/pubmed/23746830)
The advent of H7N9 in early 2013 is of concern for a number of reasons, including its capability to infect humans, the lack of clarity in the etiology of infection, and because the human population does ...

HIDARI KI, Yamaguchi M, Ueno F, Abe T, et al. Influenza virus utilizes N-linked sialoglycans as receptors in A549 cells. Biochem Biophys Res Commun. 2013 Jun 4.  Abstract  
submitted by kickingbird at Jun, 16, 2013 from Biochem Biophys Res Commun. 2013 Jun 4 (via http://www.ncbi.nlm.nih.gov/pubmed/23747419)
Influenza viruses (IFVs) recognize sialoglycans expressed on the host cell surface. To understand the mechanisms underlying tissue and host tropisms of IFV, it is essential to elucidate the molecular interaction ...

Palù G, Loregian A.. Inhibition of herpesvirus and influenza virus replication by blocking polymerase subunit interactions. Antiviral Res. 2013 Jun 5.  Abstract  
submitted by kickingbird at Jun, 16, 2013 from Antiviral Res. 2013 Jun 5 (via http://www.ncbi.nlm.nih.gov/pubmed/23748148)
Protein-protein interactions (PPIs) play a key role in many biological processes, including virus replication in the host cell. Since most of the PPIs are functionally essential, a possible strategy to ...

Rimmelzwaan GF, Katz JM.. Immune responses to infection with H5N1 influenza virus. Virus Res. 2013 Jun 1. pii: S0168-1702(13)00176-7..  Abstract  
submitted by kickingbird at Jun, 9, 2013 from Virus Res. 2013 Jun 1. pii: S0168-1702(13)00176-7. (via http://www.ncbi.nlm.nih.gov/pubmed/23735534)
Influenza A H5N1 viruses remain a substantial threat to global public health. In particular, the expanding genetic diversity of H5N1 viruses and the associated risk for human adaptation underscore the ...

Guan Y, Smith GJ.. The emergence and diversification of panzootic H5N1 influenza viruses. Virus Res. 2013 Jun 1. pii: S0168-1702(13)00177-9.  Abstract  
submitted by kickingbird at Jun, 9, 2013 from Virus Res. 2013 Jun 1. pii: S0168-1702(13)00177-9 (via http://www.ncbi.nlm.nih.gov/pubmed/23735533)
The Asian highly pathogenic avian influenza H5N1 virus was first detected in the goose population of Guangdong, China in 1996. The viruses in this lineage are unique in their ecological success, demonstrating ...

Sonnberg S, Webby RJ, Webster RG. Natural History of Highly Pathogenic Avian Influenza H5N1. Virus Res. 2013 Jun 1. pii: S0168-1702(13)00174-3..  Abstract  
submitted by kickingbird at Jun, 9, 2013 from Virus Res. 2013 Jun 1. pii: S0168-1702(13)00174-3. (via http://www.ncbi.nlm.nih.gov/pubmed/23735535)
The ecology of highly pathogenic avian influenza (HPAI) H5N1 has significantly changed from sporadic outbreaks in terrestrial poultry to persistent circulation in terrestrial and aquatic poultry and potentially ...

HU Y, Lu S, Song Z, Wang W, et al. Association between adverse clinical outcome in human disease caused by novel influenza A H7N9 virus and sustained viral shedding and emergence of antiviral resistance. Lancet. 2013 May 29. pii: S0140-6736(13)61125-3.  Abstract  
submitted by kickingbird at Jun, 9, 2013 from Lancet. 2013 May 29. pii: S0140-6736(13)61125-3 (via http://www.ncbi.nlm.nih.gov/pubmed/23726392)
BACKGROUND: On March 30, a novel influenza A subtype H7N9 virus (A/H7N9) was detected in patients with severe respiratory disease in eastern China. Virological factors associated with a poor clinical ...

SUN X, Jayaraman A, Maniprasad P, Raman R, et al. N-linked Glycosylation of the hemagglutinin protein influences virulence and antigenicity of the 1918 pandemic and seasonal H1N1 influenza A viruses. J Virol. 2013 Jun 5..  Abstract  
submitted by kickingbird at Jun, 9, 2013 from J Virol. 2013 Jun 5. (via http://www.ncbi.nlm.nih.gov/pubmed/23740978)
The hemagglutinin (HA) protein is a major virulence determinant for the 1918 pandemic virus, however it encodes no known virulence-associated determinants. In comparison to seasonal influenza viruses of ...

INGLIS NJ, Bagnall H, Janmohamed K, Suleman S, et. Measuring the effect of influenza A(H1N1)pdm09: the epidemiological experience in the West Midlands, England during the ´containment´ phase. Epidemiol Infect. 2013 Jun 4:1-10.  Abstract  
submitted by kickingbird at Jun, 9, 2013 from Epidemiol Infect. 2013 Jun 4:1-10 (via http://www.ncbi.nlm.nih.gov/pubmed/23731730)
SUMMARY The West Midlands was the first English region to report sustained community transmission during the 'containment' phase of the influenza A(H1N1)pdm09 pandemic in England. To describe the epidemiological ...

Huang Y, Zhu W, Zeng X, Li S, Li X, Lu C.. Innate and adaptive immune responses in patients with pandemic influenza A(H1N1)pdm09. Arch Virol. 2013 Jun 1..  Abstract  
submitted by kickingbird at Jun, 9, 2013 from Arch Virol. 2013 Jun 1. (via http://www.ncbi.nlm.nih.gov/pubmed/23728719)
Innate and adaptive immune responses play critical roles in the body's defense against viruses. We investigated the host immune response against the 2009 pandemic H1N1 influenza virus [A(H1N1)pdm09] in ...

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