Patricia J. Campbell, Shamika Danzy, Constantinos. The M Segment of the 2009 Pandemic Influenza Virus Confers Increased Neuraminidase Activity, Filamentous Morphology, and Efficient Contact Transmissibility to A/Puerto Rico/8/1934-Based Reassortant Vi. J. Virol. April 2014 vol. 88 no. 7 3802-3814. Abstract
submitted by kickingbird at Mar, 20, 2014 from J. Virol. April 2014 vol. 88 no. 7 3802-3814 (via http://jvi.asm.org/content/88/7/3802.abstract)
The 2009 H1N1 lineage represented the first detection of a novel, highly transmissible influenza A virus genotype: six gene segments originated from the North American triple-reassortant swine lineage, ... Lee YJ, Kang HM, Lee EK, Song BM, Jeong J, Kwon YK. Novel Reassortant Influenza A(H5N8) Viruses, South Korea, 2014. Emerg Infect Dis. 2014 Jun. Full Text
submitted by kickingbird at Mar, 17, 2014 from Emerg Infect Dis. 2014 Jun (via http://wwwnc.cdc.gov/eid/article/20/6/14-0233_article.htm)
Highly pathogenic avian influenza (HPAI) viruses have caused considerable economic losses to the poultry industry and poses potential threats to animal and human health (www.oie.int/en/ and www.who.int/en/). ... SUN Y, Xu Q, Shen Y, Liu L, et al. Naturally occurring mutations in the PA gene are key contributors to increased virulence of pandemic H1N1/09 influenza virus in mice.. J Virol. 2014. Abstract
submitted by kickingbird at Feb, 16, 2014 from J Virol. 2014 (via http://www.ncbi.nlm.nih.gov/pubmed/24522908)
We examined the molecular basis of virulence of pandemic H1N1/09 influenza viruses by reverse genetics based on two H1N1/09 virus isolates (A/California/04/2009 [CA04] and A/swine/Shandong/731/2009 [SD731]) ... TARNOW C, Engels G, Arendt A, Schwalm F, et al. TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 influenza A virus in mice. J Virol. 2014 Feb 12. Abstract
submitted by kickingbird at Feb, 16, 2014 from J Virol. 2014 Feb 12 (via http://www.ncbi.nlm.nih.gov/pubmed/24522916)
Cleavage of the hemagglutinin (HA) by host proteases is essential for the infectivity of influenza viruses. We have analysed here the role of the serine protease TMPRSS2 activating HA in the human respiratory ... NEUMANN G, Macken CA, Kawaoka Y. Identification of amino acid changes that may have been critical for the genesis of A(H7N9) influenza viruses. J Virol. 2014 Feb 12. Abstract
submitted by kickingbird at Feb, 16, 2014 from J Virol. 2014 Feb 12 (via http://www.ncbi.nlm.nih.gov/pubmed/24522919)
Novel influenza A viruses of the H7N9 subtype [A(H7N9)] emerged in the spring of 2013 in China and have infected 163 people as of January 10, 2014; fifty of them died of the severe respiratory infection ... YANG H, Chang JC, Guo Z, Carney PJ, et al. Structural stability of influenza A(H1N1)pdm09 virus hemagglutinins. J Virol. 2014 Feb 12.. Abstract
submitted by kickingbird at Feb, 16, 2014 from J Virol. 2014 Feb 12. (via http://www.ncbi.nlm.nih.gov/pubmed/24522930)
The non-covalent interactions that mediate trimerization of the influenza hemagglutinin (HA) are important determinants of its biological activities. Recent studies have demonstrated that mutations in ... HE L, Wu Q, Jiang K, Duan Z, et al. Differences in transmissibility and pathogenicity of reassortants between H9N2 and 2009 pandemic H1N1 influenza A viruses from humans and swine. Arch Virol. 2014 Feb 9. Abstract
submitted by kickingbird at Feb, 16, 2014 from Arch Virol. 2014 Feb 9 (via http://www.ncbi.nlm.nih.gov/pubmed/24510170)
Both H9N2 subtype avian influenza and 2009 pandemic H1N1 viruses (pH1N1) can infect humans and pigs, which provides the opportunity for virus reassortment, leading to the genesis of new strains with potential ... IVACHTCHENKO AV, Ivanenkov YA, Mitkin OD, Yamanush. A novel influenza virus neuraminidase inhibitor AV5027. Antiviral Res. 2013 Oct 24. pii: S0166-3542. Abstract
submitted by kickingbird at Feb, 16, 2014 from Antiviral Res. 2013 Oct 24. pii: S0166-3542 (via http://www.ncbi.nlm.nih.gov/pubmed/24513312)
A medium-sized focused library of novel Oseltamivir structural analogues with promising antiviral activity was successfully synthesized using a combinatorial approach. The synthesized compounds were then ... SH Wei, etc.,al. Human infection with avian influenza A H6N1 virus: an epidemiological analysis. The Lancet Respiratory Medicine, Volume 1, Issue. Abstract
submitted by kickingbird at Feb, 5, 2014 from The Lancet Respiratory Medicine, Volume 1, Issue (via http://www.thelancet.com/journals/lanres/article/PIIS2213-26)
Background
Avian influenza A H6N1 virus is one of the most common viruses isolated from wild and domestic avian species, but human infection with this virus has not been previously reported. We report ... Chen H, Yuan H, Gao R, et al. Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study. Lancet 2014 (published online Feb 4). Abstract
submitted by kickingbird at Feb, 5, 2014 from Lancet 2014 (published online Feb 4) (via http://www.thelancet.com/journals/lancet/article/PIIS0140-67)
Background
Human infections with different avian influenza viruses—eg, H5N1, H9N2, and H7N9—have raised concerns about pandemic potential worldwide. We report the first human infection with a novel ... WHO. Background and summary of human infection with influenza A(H7N9) virus. WHO. Abstract
submitted by kickingbird at Feb, 2, 2014 from WHO (via http://www.who.int/influenza/human_animal_interface/20140131)
in association with poultry outbreaks. The infections mainly resulted in conjunctivitis and mild upper respiratory symptoms, with the exception of one death, which occurred in the Netherlands.Since the ... Jones JC, Sonnberg S, Ko?er ZA, Shanmuganatham K,. Possible Role of Songbirds and Parakeets in Transmission of Influenza A(H7N9) Virus to Humans. Emerg Infect Dis. 2014 Mar. Abstract
submitted by kickingbird at Feb, 2, 2014 from Emerg Infect Dis. 2014 Mar (via http://wwwnc.cdc.gov/eid/article/20/3/13-1271_article.htm)
Avian-origin influenza A(H7N9) recently emerged in China, causing severe human disease. Several subtype H7N9 isolates contain influenza genes previously identified in viruses from finch-like birds. Because ... Verhagen JH, Majoor G, Lexmond P, Vuong O, Kasemir. Epidemiology of Influenza A Virus among Black-headed Gulls, the Netherlands, 2006–2010. Emerg Infect Dis. 2014 Jan. Abstract
submitted by kickingbird at Jan, 28, 2014 from Emerg Infect Dis. 2014 Jan (via http://wwwnc.cdc.gov/eid/article/20/1/13-0984_article.htm)
We sampled 7,511 black-headed gulls for influenza virus in the Netherlands during 2006–2010 and found that subtypes H13 and H16 caused annual epidemics in fledglings on colony sites. Our findings validate ... Guo L, Zhang X, Ren L, Yu X, Chen L, Zhou H, et al. Human Antibody Responses to Avian Influenza A(H7N9) Virus, 2013. 2013. Emerg Infect Dis. 2014 Feb. Abstract
submitted by kickingbird at Jan, 27, 2014 from 2013. Emerg Infect Dis. 2014 Feb (via http://wwwnc.cdc.gov/eid/article/20/2/13-1094_article.htm)
Understanding host antibody response is crucial for predicting disease severity and for vaccine development. We investigated antibody responses against influenza A(H7N9) virus in 48 serum samples from ... Komadina N, McVernon J, Hall R, Leder K.. A Historical Perspective of Influenza A(H1N2) Virus. Emerg Infect Dis. 2014 Jan. Abstract
submitted by kickingbird at Jan, 27, 2014 from Emerg Infect Dis. 2014 Jan (via http://wwwnc.cdc.gov/eid/article/20/1/12-1848_article.htm)
The emergence and transition to pandemic status of the influenza A(H1N1)A(H1N1)pdm09) virus in 2009 illustrated the potential for previously circulating human viruses to re-emerge in humans and cause a ... Westgeest KB, Russell CA, Lin X, Spronken MI, et a. Genome-wide Analysis of Reassortment and Evolution of Human Influenza A(H3N2) Viruses Circulating between 1968 and 2011. J Virol 2013.. Abstract
submitted by kickingbird at Jan, 4, 2014 from J Virol 2013. (via http://www.ncbi.nlm.nih.gov/m/pubmed/24371052/)
Influenza A(H3N2) viruses became widespread in humans during the 1968 H3N2 virus pandemic and have been a major cause of influenza epidemics ever since. The viruses evolve continuously by reassortment ... Yamayoshi S, Yamada S, Fukuyama S, Murakami S, et. Virulence-Affecting Amino Acid Changes in the PA Protein of H7N9 Influenza A Viruses. J Virol 2013. Abstract
submitted by kickingbird at Jan, 4, 2014 from J Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24371069/)
Novel avian-origin influenza A(H7N9) viruses were first reported to infect humans in March 2013. To date, 143 human cases, including 45 deaths, have been recorded. By using sequence comparisons and phylogenetic ... Bissel SJ, Wang G, Carter DM, Crevar CJ, et al.. H1N1, but not H3N2, influenza A virus infection protects ferrets from H5N1 encephalitis. J Virol 2013.. Abstract
submitted by kickingbird at Jan, 4, 2014 from J Virol 2013. (via http://www.ncbi.nlm.nih.gov/m/pubmed/24371072/)
Seasonal influenza causes substantial morbidity and mortality because of efficient human-to-human spread. Rarely, zoonotic strains of influenza virus spread to humans, where they have the potential to ... Binh NT, Wakai C, Kawaguchi A, Nagata K, et al. Involvement of the N-terminal portion of influenza virus RNA polymerase subunit PB1 in nucleotide recognition. Biochem Biophys Res Commun 2013 Dec 19. pii: S0006. Abstract
submitted by kickingbird at Jan, 4, 2014 from Biochem Biophys Res Commun 2013 Dec 19. pii: S0006 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24361882/)
The influenza virus PB1 protein functions as a catalytic subunit of the viral RNA-dependent RNA polymerase and contains the highly conserved motifs of RNA-dependent RNA polymerases together with putative ... Varich NL, Sadykova GK, Prilipov AG, Kochergin-Nik. Location and architecture of an antibody-binding site of influenza A virus nucleoprotein. Arch Virol 2013. Abstract
submitted by kickingbird at Jan, 4, 2014 from Arch Virol 2013 (via http://www.ncbi.nlm.nih.gov/m/pubmed/24357080/)
Amino acid positions recognized by monoclonal antibodies (MAbs) in the influenza A virus nucleoprotein (NP) have been reported. As these residues were scattered in the three-dimensional (3D) structure ... 7508 items, 20/Page, Page[259/376][|<<] [|<] [251] [252] [253] [254] [255] [256] [257] [258] [259] [260] [>|] [>>|] |
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