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2024-5-3 1:29:41
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Donis RO; The Influenza Cell Culture Working Group. Performance characteristics of qualified cell lines for isolation and propagation of influenza viruses for vaccine manufacturing.. Vaccine. 2014 Jun 24. pii: S0264-410X(14)00846-9..  Abstract  
submitted by kickingbird at Jul, 7, 2014 from Vaccine. 2014 Jun 24. pii: S0264-410X(14)00846-9. (via http://www.ncbi.nlm.nih.gov/pubmed/24975811)
Cell culture is now available as a method for the production of influenza vaccines in addition to eggs. In accordance with currently accepted practice, viruses recommended as candidates for vaccine manufacture ...

AXELSEN JB, Yaari R, Grenfell BT, Stone L, et al. Multiannual forecasting of seasonal influenza dynamics reveals climatic and evolutionary drivers. Proc Natl Acad Sci U S A. 2014;111:9538-42.  Abstract  
submitted by kickingbird at Jul, 7, 2014 from Proc Natl Acad Sci U S A. 2014;111:9538-42 (via http://www.ncbi.nlm.nih.gov/pubmed/24979763)
Human influenza occurs annually in most temperate climatic zones of the world, with epidemics peaking in the cold winter months. Considerable debate surrounds the relative role of epidemic dynamics, viral ...

KANG HM, Lee EK, Song BM, Jeong J, et al. Genetic and pathogenic characteristics of H1 avian and swine influenza A viruses. J Gen Virol. 2014 Jun 27.  Abstract  
submitted by kickingbird at Jul, 7, 2014 from J Gen Virol. 2014 Jun 27 (via http://www.ncbi.nlm.nih.gov/pubmed/24973238)
This study examined the potential for cross-species transmission of influenza viruses by comparing the genetic and pathogenic characteristics of H1 avian influenza viruses (AIVs) with different host origins ...

MOON H, Hong M, Kim JK, Seon B, et al. H3N2 canine influenza virus with the matrix gene from the pandemic A/H1N1 virus: infection dynamics in dogs and ferrets. Epidemiol Infect. 2014 Jun 30:1-9.  Abstract  
submitted by kickingbird at Jul, 7, 2014 from Epidemiol Infect. 2014 Jun 30:1-9 (via http://www.ncbi.nlm.nih.gov/pubmed/24977303)
After an outbreak of pandemic influenza A/H1N1 (pH1N1) virus, we had previously reported the emergence of a recombinant canine influenza virus (CIV) between the pH1N1 virus and the classic H3N2 CIV. Our ...

HAMILTON BS, Chung C, Cyphers SY, Rinaldi VD, et a. Inhibition of influenza virus infection and hemagglutinin cleavage by the protease inhibitor HAI-2. Biochem Biophys Res Commun. 2014 Jun 27.  Abstract  
submitted by kickingbird at Jul, 7, 2014 from Biochem Biophys Res Commun. 2014 Jun 27 (via http://www.ncbi.nlm.nih.gov/pubmed/24978308)
Influenza virus remains a significant concern to public health, with the continued potential for a high fatality pandemic. Vaccination and antiviral therapeutics are effective measures to circumvent influenza ...

SYED MUSTHAQ S, Kumar SR, Szyporta M, Kwang J, et. Immunization with baculovirus displayed H6 hemagglutinin vaccine protects mice against lethal H6 influenza virus challenge. Antiviral Res. 2014 Jun 25. pii: S0166-3542(14)001.  Abstract  
submitted by kickingbird at Jul, 7, 2014 from Antiviral Res. 2014 Jun 25. pii: S0166-3542(14)001 (via http://www.ncbi.nlm.nih.gov/pubmed/24973759)
Low pathogenic influenza viruses of H6 hemagglutinin (HA) subtype have a high prevalence among aquatic and domestic birds and have caused outbreaks in poultry worldwide. The first human infection with ...

Ren L, Yu X, Zhao B, Wu F, Jin Q, Zhang X, et al. Infection with Possible Precursor of Avian Influenza A(H7N9) Virus in a Child, China, 2013. Emerg Infect Dis. 2014 Aug.  Abstract  
submitted by kickingbird at Jul, 4, 2014 from Emerg Infect Dis. 2014 Aug (via http://dx.doi.org/10.3201/eid2008.140325)
During the early stage of the avian influenza A(H7N9) epidemic in China in March 2013, a strain of the virus was identified in a 4-year-old boy with mild influenza symptoms. Phylogenetic analysis indicated ...

WIKRAMARATNA PS, Pybus OG, Gupta S. Contact between bird species of different lifespans can promote the emergence of highly pathogenic avian influenza strains. Proc Natl Acad Sci U S A. 2014 Jun 23..  Abstract  
submitted by kickingbird at Jun, 29, 2014 from Proc Natl Acad Sci U S A. 2014 Jun 23. (via http://www.ncbi.nlm.nih.gov/pubmed/24958867)
Outbreaks of highly pathogenic strains of avian influenza viruses (AIVs) cause considerable economic losses to the poultry industry and also pose a threat to human life. The possibility that one of these ...

AEFFNER F, Woods PS, Davis IC. Activation of A1-adenosine Receptors Promotes Leukocyte Recruitment to the Lung and Attenuates Acute Lung Injury in Mice Infected with Influenza A/WSN/33 (H1N1) Virus. J Virol. 2014 Jun 25. pii: JVI.01068-14.  Abstract  
submitted by kickingbird at Jun, 29, 2014 from J Virol. 2014 Jun 25. pii: JVI.01068-14 (via http://www.ncbi.nlm.nih.gov/pubmed/24965449)
We have shown that bronchoalveolar epithelial A1-adenosine receptors (A1-AdoR) are activated in influenza A virus-infected mice. Alveolar macrophages and neutrophils also express A1-AdoRs and we hypothesized ...

OHKURA T, Momose F, Ichikawa R, Takeuchi K, et al. Influenza A virus hemagglutinin and neuraminidase mutually accelerate their apical targeting through clustering of lipid rafts. J Virol. 2014 Jun 25. pii: JVI.00586-14.  Abstract  
submitted by kickingbird at Jun, 29, 2014 from J Virol. 2014 Jun 25. pii: JVI.00586-14 (via http://www.ncbi.nlm.nih.gov/pubmed/24965459)
In polarized epithelial cells, influenza A virus hemagglutinin (HA) and neuraminidase (NA) are intrinsically associated with lipid rafts and target the apical plasma membrane for viral assembly and budding. ...

WU NC, Young AP, Al-Mawsawi LQ, Olson CA, et al. High-throughput identification of loss-of-function mutations for anti-interferon activity in influenza A virus NS segment. J Virol. 2014 Jun 25. pii: JVI.01494-14..  Abstract  
submitted by kickingbird at Jun, 29, 2014 from J Virol. 2014 Jun 25. pii: JVI.01494-14. (via http://www.ncbi.nlm.nih.gov/pubmed/24965464)
Viral proteins often display several functions which require multiple assays to dissect their genetic basis. Here, we describe a systematic approach to screen for loss-of-function mutations that confer ...

NELSON MI, Wentworth DE, Culhane MR, Vincent AL, e. Introductions and evolution of human-origin seasonal influenza A viruses in multinational swine populations. J Virol. 2014 Jun 25. pii: JVI.01080-14.  Abstract  
submitted by kickingbird at Jun, 29, 2014 from J Virol. 2014 Jun 25. pii: JVI.01080-14 (via http://www.ncbi.nlm.nih.gov/pubmed/24965467)
The capacity of influenza A viruses to cross species barriers presents a continual threat to human and animal health. Knowledge of the human-swine interface is particularly important for understanding ...

YEN HL, Zhou J, Choy KT, Sia SF, et al. The R292 K mutation that confers resistance to neuraminidase inhibitors leads to competitive fitness loss of A/Shanghai/1/2013 (H7N9) influenza virus in ferrets.. J Infect Dis. 2014 Jun 20. pii: jiu353.  Abstract  
submitted by kickingbird at Jun, 29, 2014 from J Infect Dis. 2014 Jun 20. pii: jiu353 (via http://www.ncbi.nlm.nih.gov/pubmed/24951824)
BACKGROUND: ?The neuraminidase (NA) inhibitors are the only licensed therapeutic option for human zoonotic H7N9 infections. An NA-R292 K mutation that confers broad-spectrum resistance to NA inhibitors ...

WANG J, Li F, Sun R, Gao X, et al. Klebsiella pneumoniae Alleviates Influenza-Induced Acute Lung Injury via Limiting NK Cell Expansion. J Immunol. 2014 Jun 20. pii: 1303303..  Abstract  
submitted by kickingbird at Jun, 29, 2014 from J Immunol. 2014 Jun 20. pii: 1303303. (via http://www.ncbi.nlm.nih.gov/pubmed/24951819)
A protective effect induced by bacterial preinfection upon a subsequent lethal influenza virus infection has been observed, but the underlying immune mechanisms have not yet been fully elucidated. In this ...

HIRATA N, Suizu F, Matsuda-Lennikov M, Edamura T,. Inhibition of Akt kinase activity suppresses entry and replication of influenza virus. Biochem Biophys Res Commun. 2014 Jun 24..  Abstract  
submitted by kickingbird at Jun, 29, 2014 from Biochem Biophys Res Commun. 2014 Jun 24. (via http://www.ncbi.nlm.nih.gov/pubmed/24971535)
The possibility of the pandemic spread of influenza viruses highlights the need for an effective cure for this life-threatening disease. Influenza A virus, belonging to a family of orthomyxoviruses, is ...

YIN X, Zhao FR, Zhou DH, Wei P, et al. Serological report of pandemic and seasonal human influenza virus infection in dogs in southern China. Arch Virol. 2014 Jun 26..  Abstract  
submitted by kickingbird at Jun, 29, 2014 from Arch Virol. 2014 Jun 26. (via http://www.ncbi.nlm.nih.gov/pubmed/24965232)
From January to July 2012, we looked for evidence of subclinical A (H1N1) pdm09 and seasonal human influenza viruses infections in healthy dogs in China. Sera from a total of 1920 dogs were collected from ...

Yondon M, Zayat B, Nelson MI, Heil GL, Anderson BD. Equine Influenza A(H3N8) Virus Isolated from Bactrian Camel, Mongolia. Emerg Infect Dis. 2014 Dec.  Abstract  
submitted by kickingbird at Jun, 28, 2014 from Emerg Infect Dis. 2014 Dec (via http://wwwnc.cdc.gov/eid/article/20/12/14-0435_article)
Because little is known about the ecology of influenza viruses in camels, 460 nasal swab specimens were collected from healthy (no overt illness) Bactrian camels in Mongolia during 2012. One specimen was ...

Qi W, Zhou X, Shi W, Huang L, Xia W, Liu D, Li H,. Genesis of the novel human-infecting influenza A(H10N8) virus and potential genetic diversity of the virus in poultry, China. Euro Surveill. 2014;19(25):pii=20841.  Abstract  
submitted by kickingbird at Jun, 27, 2014 from Euro Surveill. 2014;19(25):pii=20841 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
Human infection with a novel influenza A(H10N8) virus was first described in China in December 2013. However, the origin and genetic diversity of this virus is still poorly understood. We performed a phylogenetic ...

Wang D, Yang L, Gao R, Zhang X, Tan Y, Wu A, Zhu W. Genetic tuning of the novel avian influenza A(H7N9) virus during interspecies transmission, China, 2013. Euro Surveill. 2014;19(25):pii=20836.  Abstract  
submitted by kickingbird at Jun, 27, 2014 from Euro Surveill. 2014;19(25):pii=20836 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
A novel avian influenza A(H7N9) virus causing human infection emerged in February 2013 in China. To elucidate the mechanism of interspecies transmission, we compared the signature amino acids of avian ...

Hu J, Zhu Y, Zhao B, Li J, Liu L, Gu K, Zhang W, S. Limited human-to-human transmission of avian influenza A(H7N9) virus, Shanghai, China, March to April 2013. Euro Surveill. 2014;19(25):pii=20838.  Abstract  
submitted by kickingbird at Jun, 27, 2014 from Euro Surveill. 2014;19(25):pii=20838 (via http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId=2)
In April 2013, two members of one family were successively confirmed as cases of avian influenza A(H7N9) virus infection in Shanghai, China. Respiratory specimens from the two cases and their close contacts ...

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