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2024-3-29 18:21:02
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MI Nelson, DE Wentworth, SR Das. Evolutionary dynamics of influenza A viruses in US exhibition swine. J Infect Dis. (2015) doi:.  Abstract  
submitted by kickingbird at Aug, 7, 2015 from J Infect Dis. (2015) doi: (via http://jid.oxfordjournals.org/content/early/2015/08/03/infdi)
The role of exhibition swine in influenza A virus (IAVs) transmission was recently demonstrated by over 300 human infections of H3N2v viruses while attending agricultural fairs. Through active IAV surveillance ...

Leung YH, To MK, Lam TS, et al. Epidemiology of human influenza A(H7N9) infection in Hong Kong. J Microbiol Immunol Infect. 2015 Jun.  Abstract  
submitted by kickingbird at Aug, 5, 2015 from J Microbiol Immunol Infect. 2015 Jun (via http://www.e-jmii.com/article/S1684-1182(15)00772-0/fulltext)
Background/Purpose We conducted a case series study to review the epidemiology of human influenza A(H7N9) infection reported in Hong Kong. Methods We reviewed case records of confirmed human cases of ...

Yang ZF, Mok CK, Peiris JS, Zhong NS.. Human Infection with a Novel Avian Influenza A(H5N6) Virus. N Engl J Med 2015; 373:487-489.  Abstract  
submitted by kickingbird at Aug, 2, 2015 from N Engl J Med 2015; 373:487-489 (via http://www.nejm.org/doi/full/10.1056/NEJMc1502983)
Multiple reassortant strains of novel, highly pathogenic avian influenza A(H5) viruses in clade 2.3.4.4 have recently emerged and spread in Asia, Europe, and North America, giving rise to multiple subtypes ...

HARTMANN BM, Thakar J, Albrecht RA, Avey S, et al. Human dendritic cell response signatures distinguish 1918, pandemic and seasonal H1N1 influenza viruses. J Virol. 2015 Jul 29. pii: JVI.01523-15.  Abstract  
submitted by kickingbird at Aug, 2, 2015 from J Virol. 2015 Jul 29. pii: JVI.01523-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26223639)
Influenza viruses continue to present global threats to human health. Antigenic drift and shift, genetic reassortment, and cross-species transmission generate new strains with differences in epidemiology ...

CHENG YH, Wang CH, You SH, Hsieh NH, et al. Assessing coughing-induced influenza droplet transmission and implications for infection risk control. Epidemiol Infect. 2015 Jul 27:1-13..  Abstract  
submitted by kickingbird at Aug, 2, 2015 from Epidemiol Infect. 2015 Jul 27:1-13. (via http://www.ncbi.nlm.nih.gov/pubmed/26211781)
Indoor transmission of respiratory droplets bearing influenza within humans poses high risks to respiratory function deterioration and death. Therefore, we aimed to develop a framework for quantifying ...

Wu H, Peng X, Peng X, Wu N.. Molecular characterization of a reassortant H11N9 subtype avian influenza virus isolated from a domestic duck in Eastern China. Arch Virol. 2015 Jul 28..  Abstract  
submitted by kickingbird at Aug, 2, 2015 from Arch Virol. 2015 Jul 28. (via http://www.ncbi.nlm.nih.gov/pubmed/26212362)
During surveillance for avian influenza viruses (AIVs) in live-poultry markets in Eastern China in 2013, an H11N9 AIV was isolated from a domestic duck. Phylogenetic analysis showed that this strain received ...

Joanna A. Pulit-Penaloza, Xiangjie Sun, Hannah M.. Pathogenesis and transmission of novel HPAI H5N2 and H5N8 avian influenza viruses in ferrets and mice. Journal of Virology.  Abstract  
submitted by kickingbird at Jul, 31, 2015 from Journal of Virology (via http://jvi.asm.org/content/early/2015/07/24/JVI.01438-15.abs)
A novel highly pathogenic avian influenza (HPAI) H5N8 virus, first detected in January 2014 in poultry and wild birds in South Korea, has spread throughout Asia and Europe, and caused outbreaks in Canada ...

Yang W, Cowling BJ, Lau EHY, Shaman J. Forecasting Influenza Epidemics in Hong Kong. PLoS Comput Biol 11(7): e1004383. doi:10.1371/jour.  Abstract  
submitted by kickingbird at Jul, 31, 2015 from PLoS Comput Biol 11(7): e1004383. doi:10.1371/jour (via http://journals.plos.org/ploscompbiol/article?id=10.1371/jou)
Recent advances in mathematical modeling and inference methodologies have enabled development of systems capable of forecasting seasonal influenza epidemics in temperate regions in real-time. However, ...

Wu, Y. et al.. A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus. Nature Communications.  Abstract  
submitted by kickingbird at Jul, 28, 2015 from Nature Communications (via http://www.nature.com/ncomms/2015/150721/ncomms8708/full/nco)
Effective annual influenza vaccination requires frequent changes in vaccine composition due to both antigenic shift for different subtype hemagglutinins (HAs) and antigenic drift in a particular HA. Here ...

MEDINA J, Boukhebza H, De Saint Jean A, Sodoyer R,. Optimization of influenza A vaccine virus by reverse genetic using chimeric HA and NA genes with an extended PR8 backbone. Vaccine. 2015 Jul 20. pii: S0264-410X(15)00981-0..  Abstract  
submitted by kickingbird at Jul, 27, 2015 from Vaccine. 2015 Jul 20. pii: S0264-410X(15)00981-0. (via http://www.ncbi.nlm.nih.gov/pubmed/26206270)
The yield of influenza antigen may significantly vary between vaccine strains; for example the A/California/07/09 (H1N1)-X179A vaccine virus, prepared during 2009 influenza pandemic, presented a low antigen ...

DLUGOLENSKI D, Jones L, Howerth E, Wentworth D, et. Swine Influenza Virus PA and Neuraminidase Gene Reassortment into Human H1N1 Influenza Virus Is Associated with an Altered Pathogenic Phenotype Linked to Increased MIP-2 Expression. J Virol. 2015 May;89(10):5651-67..  Abstract  
submitted by kickingbird at Jul, 27, 2015 from J Virol. 2015 May;89(10):5651-67. (via http://www.ncbi.nlm.nih.gov/pubmed/25762737)
Swine are susceptible to infection by both avian and human influenza viruses, and this feature is thought to contribute to novel reassortant influenza viruses. In this study, the influenza virus reassortment ...

VER LS, Marcos-Villar L, Landeras-Bueno S, Nieto A. The cellular factor NXP2/MORC3 is a positive regulator for influenza virus multiplication. J Virol. 2015 Jul 22. pii: JVI.01530-15..  Abstract  
submitted by kickingbird at Jul, 27, 2015 from J Virol. 2015 Jul 22. pii: JVI.01530-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26202233)
Transcription and replication of the influenza A virus are carried out in the nucleus of the infected cells in the context of viral ribonucleoproteins (RNPs). The viral polymerase responsible for these ...

SHIN DL, Hatesuer B, Bergmann S, Nedelko T, et al. Protection from severe influenza infections in mice carrying the Mx1 influenza resistance gene strongly depends on genetic background. J Virol. 2015 Jul 22. pii: JVI.01305-15.  Abstract  
submitted by kickingbird at Jul, 27, 2015 from J Virol. 2015 Jul 22. pii: JVI.01305-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26202236)
Influenza infections represent a serious threat to human health. Both extrinsic and intrinsic factors determine the severity of influenza disease. The MX dynamin-like GTPase 1 (Mx1) gene has been shown ...

LUK GS, Leung CY, Sia SF, Choy KT, et al. Transmission of H7N9 influenza viruses with polymorphism at PB2 residue 627 in chickens and ferrets. J Virol. 2015 Jul 22. pii: JVI.01444-15.  Abstract  
submitted by kickingbird at Jul, 27, 2015 from J Virol. 2015 Jul 22. pii: JVI.01444-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26202239)
Poultry exposure is a major risk factor for human H7N9 zoonotic infections of which the mode of transmission remains unclear. We studied the transmission of genetically related poultry and human H7N9 influenza ...

WATSON SJ, Langat P, Reid SM, Lam TT, et al. Molecular Epidemiology and Evolution of Influenza Viruses Circulating within European Swine between 2009 and 2013. J Virol. 2015 Jul 22. pii: JVI.00840-15.  Abstract  
submitted by kickingbird at Jul, 27, 2015 from J Virol. 2015 Jul 22. pii: JVI.00840-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26202246)
The emergence in humans of the A(H1N1)pdm09 influenza virus, a complex reassortant virus of swine origin, highlighted the importance of worldwide influenza virus surveillance in swine. To date, large-scale ...

LERSRITWIMANMAEN P, Na-Ek P, Thanunchai M, Thewsoo. The presence of monocytes enhances the susceptibility of B cells to highly pathogenic avian influenza (HPAI) H5N1 virus possibly through the increased expression of α2,3 SA receptor. Biochem Biophys Res Commun. 2015 Jul 15..  Abstract  
submitted by kickingbird at Jul, 27, 2015 from Biochem Biophys Res Commun. 2015 Jul 15. (via http://www.ncbi.nlm.nih.gov/pubmed/26187669)
The highly pathogenic avian influenza (HPAI) H5N1 virus causes severe systemic infection in avian and mammalian species, including humans by first targeting immune cells. This subsequently renders the ...

Arriola CS, Nelson DI, Deliberto TJ, Blanton L, Kn. Infection Risk for Persons Exposed to Highly Pathogenic Avian Influenza A H5 Virus–Infected Birds, United States, December 2014–March 2015. Emerg Infect Dis. 2015 Dec.  Abstract  
submitted by kickingbird at Jul, 25, 2015 from Emerg Infect Dis. 2015 Dec (via http://wwwnc.cdc.gov/eid/article/21/12/15-0904_article)
Newly emerged highly pathogenic avian influenza (HPAI) A H5 viruses have caused outbreaks among birds in the United States. These viruses differ genetically from HPAI H5 viruses that previously caused ...

Nelson MI, Schaefer R, Gava D, Cant?o ME, Ciacci-Z. Influenza A Viruses of Human Origin in Swine, Brazil. Emerg Infect Dis. 2015 Aug.  Abstract  
submitted by kickingbird at Jul, 20, 2015 from Emerg Infect Dis. 2015 Aug (via http://wwwnc.cdc.gov/eid/article/21/8/14-1891_article)
The evolutionary origins of the influenza A(H1N1)pdm09 virus that caused the first outbreak of the 2009 pandemic in Mexico remain unclear, highlighting the lack of swine surveillance in Latin American ...

BAO H, Ma Y, Shi J, Zeng X, et al. Evaluation and application of a one-step duplex real-time reverse transcription polymerase chain reaction assay for the rapid detection of influenza A (H7N9) virus from poultry samples. Arch Virol. 2015 Jul 16..  Abstract  
submitted by kickingbird at Jul, 20, 2015 from Arch Virol. 2015 Jul 16. (via http://www.ncbi.nlm.nih.gov/pubmed/26179621)
In China, a novel reassortant influenza A (H7N9) virus, which has caused 435 cases of human infection, has recently emerged. Most cases of human infections with the H7N9 virus are known to be associated ...

XIONG X, Corti D, Liu J, Pinna D, et al. Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody. Proc Natl Acad Sci U S A. 2015 Jul 13. pii: 201510.  Abstract  
submitted by kickingbird at Jul, 20, 2015 from Proc Natl Acad Sci U S A. 2015 Jul 13. pii: 201510 (via http://www.ncbi.nlm.nih.gov/pubmed/26170284)
H5N1 avian influenza viruses remain a threat to public health mainly because they can cause severe infections in humans. These viruses are widespread in birds, and they vary in antigenicity forming three ...

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