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2026-10-9 8:11:27
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Rozek W, Kwasnik M, Socha W, Sztromwasser P, Rola. Analysis of Single Nucleotide Variants (SNVs) Induced by Passages of Equine Influenza Virus H3N8 in Embryonated Chicken Eggs. Viruses. 2021 Aug 5;13(8):1551.  Abstract  
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Aug 5;13(8):1551 (via https://www.mdpi.com/1999-4915/13/8/1551)
Vaccination is an effective method for the prevention of influenza virus infection. Many manufacturers use embryonated chicken eggs (ECE) for the propagation of vaccine strains. However, the adaptation ...

Sulaiman L, Shittu I, Fusaro A, Inuwa B, Zecchin B. Live Bird Markets in Nigeria: A Potential Reservoir for H9N2 Avian Influenza Viruses. Viruses. 2021 Jul 24;13(8):1445.  Abstract  
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Jul 24;13(8):1445 (via https://www.mdpi.com/1999-4915/13/8/1445)
Since 2006, multiple outbreaks of avian influenza (AI) have been reported in Nigeria involving different subtypes. Surveillance and molecular epidemiology have revealed the vital role of live bird markets ...

Oladunni FS, Oseni SO, Martinez-Sobrido L, Chamber. Equine Influenza Virus and Vaccines. Viruses. 2021 Aug 20;13(8):1657.  Abstract  
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Aug 20;13(8):1657 (via https://www.mdpi.com/1999-4915/13/8/1657)
Equine influenza virus (EIV) is a constantly evolving viral pathogen that is responsible for yearly outbreaks of respiratory disease in horses termed equine influenza (EI). There is currently no evidence ...

Frymus T, Belák S, Egberink H, Hofmann-Lehmann R,. Influenza Virus Infections in Cats. Viruses. 2021 Jul 23;13(8):1435.  Abstract  
submitted by kickingbird at Aug, 29, 2021 from Viruses. 2021 Jul 23;13(8):1435 (via https://www.mdpi.com/1999-4915/13/8/1435)
In the past, cats were considered resistant to influenza. Today, we know that they are susceptible to some influenza A viruses (IAVs) originating in other species. Usually, the outcome is only subclinical ...

Stadtmueller MN, Bhatia S, Kiran P, Hilsch M, Reit. Evaluation of Multivalent Sialylated Polyglycerols for Resistance Induction in and Broad Antiviral Activity against Influenza A Viruses. J Med Chem. 2021 Aug 25.  Abstract  
submitted by kickingbird at Aug, 26, 2021 from J Med Chem. 2021 Aug 25 (via https://pubs.acs.org/doi/10.1021/acs.jmedchem.1c00794)
The development of multivalent sialic acid-based inhibitors active against a variety of influenza A virus (IAV) strains has been hampered by high genetic and structural variability of the targeted viral ...

Wilks LR, Joshi G, Grisham MR, Gill HS. Tyrosine-Based Cross-Linking of Peptide Antigens to Generate Nanoclusters with Enhanced Immunogenicity: Demonstration Using the Conserved M2e Peptide of Influenza A. ACS Infect Dis. 2021 Aug 25.  Abstract  
submitted by kickingbird at Aug, 26, 2021 from ACS Infect Dis. 2021 Aug 25 (via https://pubs.acs.org/doi/10.1021/acsinfecdis.1c00219)
A method of creating nanoclusters (NCs) from soluble peptide molecules is described utilizing an approach based on a tyrosine-tyrosine cross-linking reaction. A reactive tag comprising histidine and tyrosine ...

Machado MAA, Moura CS, Abrahamowicz M, Ward BJ, Pi. Relative effectiveness of influenza vaccines in elderly persons in the United States, 2012/2013-2017/2018 seasons. NPJ Vaccines. 2021 Aug 24;6(1):108.  Abstract  
submitted by kickingbird at Aug, 26, 2021 from NPJ Vaccines. 2021 Aug 24;6(1):108 (via https://www.nature.com/articles/s41541-021-00373-w)
Influenza immunization protects seniors against influenza and its potentially serious complications. It is uncertain whether standard-dose (SD) quadrivalent vaccine offers better protection over other ...

Zhang J, Huang L, Chen Y, Wang X, Liao M, Qi W. Avian influenza H10 subtype viruses continuously pose threat to public health in China. J Infect. 2021 Aug 8:S0163-4453(21)00386-8.  Abstract  
submitted by kickingbird at Aug, 25, 2021 from J Infect. 2021 Aug 8:S0163-4453(21)00386-8 (via J Infect. 2021 Aug 8:S0163-4453(21)00386-8)
Wang and colleges recently reported in this journal the first case of human infection with H10N3 virus in China. 1 In China, H10 subtype (H10N2, H10N3, H10N6, H10N7, H10N8, and et. al.) avian influenza ...

Zhang J, Ma K, Li B, Chen Y, Qiu Z, Xing J, Huang. A risk marker of tribasic hemagglutinin cleavage site in influenza A (H9N2) virus. Commun Biol. 2021 Jan 15;4(1):71.  Abstract  
submitted by kickingbird at Aug, 25, 2021 from Commun Biol. 2021 Jan 15;4(1):71 (via https://www.nature.com/articles/s42003-020-01589-7)
Low pathogenic avian influenza A(H9N2) virus is endemic worldwide and continually recruit internal genes to generate human-infecting H5N1, H5N6, H7N9, and H10N8 influenza variants. Here we show that hemagglutinin ...

Li X, Gu M, Wang X, Gao R, Bu X, Hao X, Ma J, Hu J. G1-like M and PB2 genes are preferentially incorporated into H7N9 progeny virions during genetic reassortment. BMC Vet Res. 2021 Feb 15;17(1):80.  Abstract  
submitted by kickingbird at Aug, 25, 2021 from BMC Vet Res. 2021 Feb 15;17(1):80 (via https://bmcvetres.biomedcentral.com/articles/10.1186/s12917-)
Background: Genotype S H9N2 viruses have become predominant in poultry in China since 2010. These viruses frequently donate their whole internal gene segments to other emerging influenza A subtypes such ...

Turner JCM, Barman S, Feeroz MM, Hasan MK, Akhtar. Highly Pathogenic Avian Influenza A(H5N6) Virus Clade 2.3.4.4h in Wild Birds and Live Poultry Markets, Bangladesh. Emerg Infect Dis. 2021 Sep;27(9):2492-2494..  Abstract  
submitted by kickingbird at Aug, 24, 2021 from Emerg Infect Dis. 2021 Sep;27(9):2492-2494. (via https://wwwnc.cdc.gov/eid/article/27/9/21-0819_article)
Migratory birds play a major role in spreading influenza viruses over long distances. We report highly pathogenic avian influenza A(H5N6) viruses in migratory and resident ducks in Bangladesh. The viruses ...

Pascua PNQ, Jones JC, Marathe BM, Seiler P, Caufie. Baloxavir treatment delays influenza B virus transmission in ferrets and results in limited generation of drug-resistant variants. Antimicrob Agents Chemother. 2021 Aug 23:AAC011372.  Abstract  
submitted by kickingbird at Aug, 24, 2021 from Antimicrob Agents Chemother. 2021 Aug 23:AAC011372 (via https://journals.asm.org/doi/10.1128/AAC.01137-21)
Clinical efficacy of the influenza antiviral baloxavir marboxil (baloxavir) is compromised by treatment-emergent variants harboring a polymerase acidic protein I38T substitution. However, the fitness of ...

Chakma S, Osmani MG, Akwar H, Hasan Z, Nasrin T, K. Risk Areas for Influenza A(H5) Environmental Contamination in Live Bird Markets, Dhaka, Bangladesh. Emerg Infect Dis. 2021 Sep;27(9):2399-2408.  Abstract  
submitted by kickingbird at Aug, 24, 2021 from Emerg Infect Dis. 2021 Sep;27(9):2399-2408 (via https://wwwnc.cdc.gov/eid/article/27/9/20-4447_article)
We evaluated the presence of influenza A(H5) virus environmental contamination in live bird markets (LBMs) in Dhaka, Bangladesh. By using Bernoulli generalized linear models and multinomial logistic regression ...

Blaurock C, Blohm U, Luttermann C, Holzerland J, S. The C-Terminus of Non-Structural Protein 1 (NS1) in H5N8 Clade 2.3.4.4 Avian Influenza Virus Affects Virus Fitness in Human Cells and Virulence in Mice. Emerg Microbes Infect. 2021 Aug 22:1-48..  Abstract  
submitted by kickingbird at Aug, 24, 2021 from Emerg Microbes Infect. 2021 Aug 22:1-48. (via https://www.tandfonline.com/doi/full/10.1080/22221751.2021.1)
Avian influenza viruses (AIV) H5N8 clade 2.3.4.4 pose a public health threat but the viral factors relevant for its potential adaptation to mammals are largely unknown. The non-structural protein 1 (NS1) ...

Peng HK, Dombkowski KJ, Freed GL, Creary SE, Smith. Influenza immunization coverage of children with sickle cell disease. Vaccine. 2021 Aug 17:S0264-410X(21)01072-0.  Abstract  
submitted by kickingbird at Aug, 22, 2021 from Vaccine. 2021 Aug 17:S0264-410X(21)01072-0 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Objectives: To assess receipt of annual flu immunization among children living with sickle cell disease (SCD).Methods: Receipt of flu immunization (2014-2019) by SCD status was assessed among all Michigan ...

Han T, Lai Y, Jiang Y, Liu X, Li D. Influenza A virus infects pulmonary microvascular endothelial cells leading to microvascular leakage and release of pro-inflammatory cytokines. PeerJ. 2021 Aug 3;9:e11892.  Abstract  
submitted by kickingbird at Aug, 22, 2021 from PeerJ. 2021 Aug 3;9:e11892 (via https://peerj.com/articles/11892/)
Objective: To investigate the replication of influenza A virus A/Puerto Rico/8/34 (H1N1) in pulmonary microvascular endothelial cells and its effect on endothelial barrier function.Methods: Human pulmonary ...

Flores-Torres AS, Rendon A, Salinas-Carmona MC, Sa. Human Eosinophils Reduce Viral Titer, Secrete IL-8, and Increase RIG-I Expression in Response to Influenza A H1N1 pdm09. Viral Immunol. 2021 Aug 19.  Abstract  
submitted by kickingbird at Aug, 22, 2021 from Viral Immunol. 2021 Aug 19 (via https://www.liebertpub.com/doi/10.1089/vim.2021.0004)
Eosinophils participate in the immune response against many pathogens, including viruses. Since mouse eosinophils are susceptible to influenza A virus infection and possess antiviral activity, we evaluated ...

Gao R, Zheng H, Liu K, Ji Z, Cai M, Gu M, Hu J, Li. Genesis, Evolution and Host Species Distribution of influenza A (H10N3) Virus in China. J Infect. 2021 Aug 17:S0163-4453(21)00403-5.  Abstract  
submitted by kickingbird at Aug, 22, 2021 from J Infect. 2021 Aug 17:S0163-4453(21)00403-5 (via https://www.journalofinfection.com/article/S0163-4453(21)004)
A recent article by Wang in the Journal of Infection ( 1 ) confirmed the first case of human infection with H10N3 avian influenza virus (AIV) in Zhenjiang, Jiangsu Province, China, in April 2021. Transmission ...

Chen Y, Graf L, Chen T, Liao Q, Bai T, Petric PP,. Rare variant MX1 alleles increase human susceptibility to zoonotic H7N9 influenza virus. Science. 2021 Aug 20;373(6557):918-922.  Abstract  
submitted by kickingbird at Aug, 20, 2021 from Science. 2021 Aug 20;373(6557):918-922 (via https://science.sciencemag.org/content/373/6557/918)
Zoonotic avian influenza A virus (IAV) infections are rare. Sustained transmission of these IAVs between humans has not been observed, suggesting a role for host genes. We used whole-genome sequencing ...

Cardona C, Wileman B, Malladi S, Ceballos R, Culha. The Risk of Highly Pathogenic Influenza A Virus Transmission to Turkey Hen Flocks Through Artificial Insemination. Avian Dis. 2021 Jun;65(2):303-309.  Abstract  
submitted by kickingbird at Aug, 20, 2021 from Avian Dis. 2021 Jun;65(2):303-309 (via https://bioone.org/journals/avian-diseases/volume-65/issue-2)
Artificial insemination is a routine practice for turkeys that can introduce pathogens into breeder flocks in a variety of ways. In this manuscript, a risk analysis on the potential transmission of highly ...

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