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2025-12-6 8:12:20
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Chen F, Liu T, Xu J, Huang Y, Liu S, Yang J. Key amino acid residues of neuraminidase involved in influenza A virus entry. Pathog Dis. 2019 Nov 8..  Abstract  
submitted by kickingbird at Nov, 11, 2019 from Pathog Dis. 2019 Nov 8. (via https://academic.oup.com/femspd/advance-article-abstract/doi)
Generally, influenza virus neuraminidase (NA) plays a critical role in the release stage of influenza virus. Recently, it has been found that NA may promote influenza virus to access the target cells. ...

Baek YG, et al. A novel reassortant clade 2.3.4.4 highly pathogenic avian influenza H5N6 virus identified in South Korea in 2018. Infect Genet Evol. 2019 Nov 1:104056..  Abstract  
submitted by kickingbird at Nov, 7, 2019 from Infect Genet Evol. 2019 Nov 1:104056. (via https://www.ncbi.nlm.nih.gov/pubmed/31683010)
Since 2017, clade 2.3.4.4b H5N6 highly pathogenic avian influenza viruses (HPAIVs) have been detected over a broad geographic region, including Eurasia. These viruses have evolved through reassortment ...

Tapia F, Laske T, Wasik MA, Rammhold M, Genzel Y. Production of Defective Interfering Particles of Influenza A Virus in Parallel Continuous Cultures at Two Residence Times-Insights From qPCR Measurements and Viral Dynamics Modeling. Front Bioeng Biotechnol. 2019 Oct 18;7:275.  Abstract  
submitted by kickingbird at Nov, 7, 2019 from Front Bioeng Biotechnol. 2019 Oct 18;7:275 (via https://www.frontiersin.org/articles/10.3389/fbioe.2019.0027)
Defective interfering particles (DIPs) are a natural byproduct of influenza A virus (IAV) replication. DIPs interfere with the propagation and spread of infectious standard virus (STV), reduce virus yields ...

Zhang F, et al. Phenotypic Characterization of Chinese Rhesus Macaque Plasmablasts for Cloning Antigen-Specific Monoclonal Antibodies. Front Immunol. 2019 Oct 11;10:2426.  Abstract  
submitted by kickingbird at Nov, 7, 2019 from Front Immunol. 2019 Oct 11;10:2426 (via https://www.frontiersin.org/articles/10.3389/fimmu.2019.0242)
Rhesus macaques (Macaca mulatta) are used as a human-relevant animal species for the evaluation of vaccines and as a source for cloning monoclonal antibodies (mAbs) that are highly similar to human-derived ...

Li J, Zhang K, Fan W, Zhang S, Li Y, Gu J, Zhou J,. Transcriptome Profiling Reveals Differential Effect of Interleukin-17A Upon Influenza Virus Infection in Human Cells. Front Microbiol. 2019 Oct 10;10:2344..  Abstract  
submitted by kickingbird at Nov, 7, 2019 from Front Microbiol. 2019 Oct 10;10:2344. (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0234)
Influenza A virus (IAV) has developed elegant strategies to utilize cellular proteins and pathways to promote replication and evade the host antiviral response. Identification of these sabotaged host factors ...

Sakai-Tagawa Y, Yamayoshi S, Kawaoka Y. Sensitivity of Commercially Available Influenza Rapid Diagnostic Tests in the 2018-2019 Influenza Season. Front Microbiol. 2019 Oct 11;10:2342..  Abstract  
submitted by kickingbird at Nov, 7, 2019 from Front Microbiol. 2019 Oct 11;10:2342. (via https://www.frontiersin.org/articles/10.3389/fmicb.2019.0234)
Epidemics of seasonal influenza caused by H1N1pdm09, H3N2, and type B viruses occur throughout the world. Sporadic human H5 and H7N9 virus infections are also reported in particular regions. To treat influenza ...

Yang J, Li H, Jia L, Lan X, Zhao Y, Bian H, Li Z. High expression levels of influenza virus receptors in airway of the HBV-transgenic mice. Epidemiol Infect. 2019 Nov 4;147:e297..  Abstract  
submitted by kickingbird at Nov, 7, 2019 from Epidemiol Infect. 2019 Nov 4;147:e297. (via https://www.cambridge.org/core/journals/epidemiology-and-inf)
In the human population, influenza A viruses are associated with acute respiratory illness and are responsible for millions of deaths annually. Avian and human influenza viruses typically have a different ...

Ampomah PB, Lim LHK. Influenza A virus-induced apoptosis and virus propagation. Apoptosis. 2019 Oct 30.  Abstract  
submitted by kickingbird at Nov, 3, 2019 from Apoptosis. 2019 Oct 30 (via https://www.ncbi.nlm.nih.gov/pubmed/31667646)
Influenza A viruses (IAVs) are respiratory pathogens that cause severe morbidity and mortality worldwide. They affect cellular processes such as proliferation, protein synthesis, autophagy, and apoptosis. ...

Uyeki TM, Peiris M. Novel Avian Influenza A Virus Infections of Humans. Infect Dis Clin North Am. 2019 Dec;33(4):907-932..  Abstract  
submitted by kickingbird at Nov, 3, 2019 from Infect Dis Clin North Am. 2019 Dec;33(4):907-932. (via https://www.ncbi.nlm.nih.gov/pubmed/31668198)
A high index of suspicion and early diagnosis of avian influenza A virus infection is essential reduce transmission risk. Clinical suspicion relies on eliciting a history of recent exposure to poultry ...

Leonenko V, Bobashev G. Analyzing influenza outbreaks in Russia using an age-structured dynamic transmission model. Epidemics. 2019 Jul 22:100358..  Abstract  
submitted by kickingbird at Nov, 3, 2019 from Epidemics. 2019 Jul 22:100358. (via https://www.ncbi.nlm.nih.gov/pubmed/31668495)
In this study, we addressed the ability of a minimalistic SEIR model to satisfactorily describe influenza outbreak dynamics in Russian settings. For that purpose, we calibrated an age-specific influenza ...

Kang YM, Cho HK, Kim HM, Lee MH, To TL, Kang HM. Protective efficacy of vaccines of the Korea national antigen bank against the homologous H5Nx clade 2.3.2.1 and clade 2.3.4.4 highly pathogenic avian influenza viruses. Vaccine. 2019 Oct 25.  Abstract  
submitted by kickingbird at Nov, 3, 2019 from Vaccine. 2019 Oct 25 (via https://www.ncbi.nlm.nih.gov/pubmed/31669062)
The occurrence of severe outbreaks of highly pathogenic avian influenza in Korea led to establishment of a national antigen bank for emergency preparedness. Here, we developed five vaccines for this bank ...

Ivan FX, et al. Molecular insights into evolution, mutations and receptor-binding specificity of influenza A and B viruses from outpatients and hospitalized patients in Singapore. Int J Infect Dis. 2019 Oct 25.  Abstract  
submitted by kickingbird at Nov, 3, 2019 from Int J Infect Dis. 2019 Oct 25 (via https://www.ncbi.nlm.nih.gov/pubmed/31669593)
BACKGROUND: This study compared the genomes of influenza viruses that caused mild infections among outpatients and severe infections among hospitalized patients in Singapore, and characterized their molecular ...

Escuyer KL, E Fuschino M, St George K. New York State Emergency Preparedness and Response to Influenza Pandemics 1918-2018. Trop Med Infect Dis. 2019 Oct 30;4(4)..  Abstract  
submitted by kickingbird at Nov, 3, 2019 from Trop Med Infect Dis. 2019 Oct 30;4(4). (via https://www.mdpi.com/2414-6366/4/4/132)
Emergency health preparedness and response efforts are a necessity in order to safeguard the public against major events, such as influenza pandemics. Since posting warnings of the epidemic influenza in ...

Paget J, et al. Global mortality associated with seasonal influenza epidemics: New burden estimates and predictors from the GLaMOR Project. J Glob Health. 2019 Dec;9(2):020421..  Abstract  
submitted by kickingbird at Nov, 3, 2019 from J Glob Health. 2019 Dec;9(2):020421. (via https://www.ncbi.nlm.nih.gov/pubmed/31673337)
Background: Until recently, the World Health Organization (WHO) estimated the annual mortality burden of influenza to be 250?000 to 500?000 all-cause deaths globally; however, a 2017 study indicated a ...

He G, Yang P, Yan Q, Xiong C. Debate on the compositions of influenza B in northern hemisphere seasonal influenza vaccines. Antimicrob Resist Infect Control. 2019 Oct 28;8:16.  Abstract  
submitted by kickingbird at Nov, 3, 2019 from Antimicrob Resist Infect Control. 2019 Oct 28;8:16 (via https://www.ncbi.nlm.nih.gov/pubmed/31673353)
Background: Annual influenza vaccination is the most effective way to prevent influenza. Influenza vaccines have traditionally included the hemagglutinins (HA) and neuraminidases (NA) from the two A viruses ...

Kwon JH, et al. Domestic ducks play a major role in the maintenance and spread of H5N8 highly pathogenic avian influenza viruses in South Korea. Transbound Emerg Dis. 2019 Nov 1.  Abstract  
submitted by kickingbird at Nov, 3, 2019 from Transbound Emerg Dis. 2019 Nov 1 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13406)
The H5N8 highly pathogenic avian influenza viruses (HPAIV) belonging to clade 2.3.4.4 spread from Eastern China to Korea in 2014 and caused outbreaks in domestic poultry until 2016. To understand how H5N8 ...

Stadlbauer D, et al. Broadly protective human antibodies that target the active site of influenza virus neuraminidase. Science. 2019 Oct 25;366(6464):499-504..  Abstract  
submitted by kickingbird at Oct, 29, 2019 from Science. 2019 Oct 25;366(6464):499-504. (via https://science.sciencemag.org/content/366/6464/499)
Better vaccines against influenza virus are urgently needed to provide broader protection against diverse strains, subtypes, and types. Such efforts are assisted by the identification of novel broadly ...

Wu L, et al. Characterization of H7N9 avian influenza viruses isolated from duck meat products. Transbound Emerg Dis. 2019 Oct 25..  Abstract  
submitted by kickingbird at Oct, 29, 2019 from Transbound Emerg Dis. 2019 Oct 25. (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13398)
Avian influenza H7N9 viruses have caused five epidemic waves of human infections since the first human cases were reported in 2013. In 2016, the initial low pathogenic avian influenza (LPAI) H7N9 viruses ...

Harada Y, et al. Comparison of suspension MDCK cells, adherent MDCK cells, and LLC-MK2 cells for selective isolation of influenza viruses to be used as vaccine seeds. Influenza Other Respir Viruses. 2019 Oct 25..  Abstract  
submitted by kickingbird at Oct, 29, 2019 from Influenza Other Respir Viruses. 2019 Oct 25. (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12694)
BACKGROUND: Cell-based influenza vaccines can solve the problem of the frequent occurrence of egg adaptation-associated antigenic changes observed in egg-based vaccines. Seed viruses for cell-based vaccines ...

Matsuzawa Y, et al. Antigenic Change in Human Influenza A(H2N2) Viruses Detected by Using Human Plasma from Aged and Younger Adult Individuals. Viruses. 2019 Oct 23;11(11)..  Abstract  
submitted by kickingbird at Oct, 29, 2019 from Viruses. 2019 Oct 23;11(11). (via https://www.mdpi.com/1999-4915/11/11/978)
Human influenza A(H2N2) viruses emerged in 1957 and were replaced by A(H3N2) viruses in 1968. The antigenicity of human H2N2 viruses has been tested by using ferret antisera or mouse and human monoclonal ...

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