A. Rico, B. Nicks, A. Lago, N. Silva-del-Rio. Insights into Cow-Level Risk Factors for HPAI H5N1 clinical disease in Lactating Holsteins from a Single Outbreak in Colorado (US). An observational study. JDS Communications. Abstract
submitted by kickingbird at Sep, 14, 2025 from JDS Communications (via https://www.sciencedirect.com/science/article/pii/S266691022)
Highly Pathogenic Avian Influenza (HPAI) H5N1 (clade 2.3.4.4b) has spilled over into dairy cattle populations in the US. A year after the initial outbreak, many uncertainties remain about the virus's epidemiology. ... Yang S-T, Hu M-H, Fang W-X, Diao H-M, Musonye HA,. H1N1pdm09 returns: a comparative study in Anhui, China. Microbiol Spectr. 2025 Sep 8:e0221824. Abstract
submitted by kickingbird at Sep, 13, 2025 from Microbiol Spectr. 2025 Sep 8:e0221824 (via https://journals.asm.org/doi/10.1128/spectrum.02218-24)
The 2022/2023 season witnessed a rapid resurgence of H1N1pdm09 in Anhui Province, China, surpassing previous years, prompting an examination of hemagglutinin (HA) gene mutations and cross-immunity in this ... Rimi NA, Fahad MH, Clark A, Sultana R, Hossain K,. Developing a method to estimate aerosol generation during poultry slaughtering and defeathering in Bangladesh: An experimental study. Build Environ . 2025 Mar:271:10.1016/j.buildenv.20. Abstract
submitted by kickingbird at Sep, 13, 2025 from Build Environ . 2025 Mar:271:10.1016/j.buildenv.20 (via https://www.sciencedirect.com/science/article/abs/pii/S03601)
Influenza viruses can be aerosolized when slaughtering infected chickens, which increases the risk of zoonotic transmission. We conducted pilot experiments to measure the concentrations of airborne particles ... Kawano K, Hoshino T, Yano Y, Matsuzaki K. Steady dimer formation by the S31N mutant of influenza A virus M2 protein in living cell membranes. Biochim Biophys Acta Biomembr. 2025 Sep 9:184456. Abstract
submitted by kickingbird at Sep, 13, 2025 from Biochim Biophys Acta Biomembr. 2025 Sep 9:184456 (via https://www.sciencedirect.com/science/article/abs/pii/S00052)
The integral matrix protein M2 of the influenza A virus (H3N2) has been proposed to form a proton-selective channel, and is a target of the antiviral drug amantadine hydrochloride (Am). A significant increase ... Maya Sangesland et al. Functional, immunogenetic, and structural convergence in influenza immunity between humans and macaques. Sci. Transl. Med.17,eady3570(2025). Abstract
submitted by kickingbird at Sep, 13, 2025 from Sci. Transl. Med.17,eady3570(2025) (via https://www.science.org/doi/10.1126/scitranslmed.ady3570)
Human B cell immunity to the influenza hemagglutinin (HA) stem, a universal vaccine target, is often stereotyped and immunogenetically restricted, posing hurdles to study outside of humans. Here, we show ... Ruifeng Xu, Minhao Gao, Nailou Zhang, Zhenhua Wei,. [preprint]Transcontinental Spread of HPAI H5N1 from South America to Antarctica via Avian Vectors. https://doi.org/10.1101/2025.09.06.674605. Abstract
submitted by kickingbird at Sep, 12, 2025 from https://doi.org/10.1101/2025.09.06.674605 (via https://www.biorxiv.org/content/10.1101/2025.09.06.674605v1)
Our study has for the first time identified H5N1 strains (clade 2.3.4.4b, genotype B3.2) in brown skuas from the Fildes Peninsula, South Shetland Islands, Antarctica. These findings indicate that highly ... Antje Steinfurth, etc.,al. [preprint]Investigating high pathogenicity avian influenza virus incursions to remote islands: Detection of H5N1 on Gough Island in the South Atlantic Ocean. https://doi.org/10.1101/2025.09.06.674618. Abstract
submitted by kickingbird at Sep, 12, 2025 from https://doi.org/10.1101/2025.09.06.674618 (via https://www.biorxiv.org/content/10.1101/2025.09.06.674618v1)
Understanding the mechanisms underlying the emergence and spread of high pathogenicity avian influenza virus (HPAIV) is critical for tracking its global dissemination, particularly via migratory seabirds, ... Lan R, Yang J, Li J, Li H, Cao X, Tao M, Chang H,. Continuous evolution of Eurasian avian-like H1N1 swine influenza viruses with pdm/09-derived internal genes enhances pathogenicity in mice. J Virol. 2025 Sep 8:e0043025. Abstract
submitted by kickingbird at Sep, 11, 2025 from J Virol. 2025 Sep 8:e0043025 (via https://journals.asm.org/doi/10.1128/jvi.00430-25)
Swine influenza A virus (swIAV) is an important zoonotic pathogen with the potential to cause human influenza pandemics. Swine are considered "mixing vessels" for generating novel reassortant influenza ... Holly A. Coombes, etc.,al. [preprint]Infection of ratites with clade 2.3.4.4b HPAIV H5N1: Potential implications for zoonotic risk. https://doi.org/10.1101/2025.09.08.674895. Abstract
submitted by kickingbird at Sep, 11, 2025 from https://doi.org/10.1101/2025.09.08.674895 (via https://www.biorxiv.org/content/10.1101/2025.09.08.674895v1)
We detected H5N1 high pathogenicity avian influenza in captive Greater Rhea (Rhea americana). Viral genetic analysis revealed the mammalian associated PB2-E627K mutation, indicating selection of mammalian-relevant ... Zhu, Y., Sun, Y., Deng, X., Cao, P., Li, S., Yu, H. Matrix Protein 1 (M1) of Influenza A Virus: Structural and Functional Insights. Emerging Microbes & Infections. Abstract
submitted by kickingbird at Sep, 10, 2025 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Enveloped viruses rely on matrix proteins for structural integrity and lifecycle progression. Matrix protein 1 (M1) is the most abundant structural protein of influenza A virus (IAV), playing a multifaceted ... Ismaila Shittu, Daniel B. Cummings, John T. Groves. Low Levels of Neutralizing Antibodies to Influenza A (H5N1) and D Viruses Among Cattle and Cattle Workers on US Farms, 2024–2025. Influenza and Other Respiratory Viruses. Abstract
submitted by kickingbird at Sep, 9, 2025 from Influenza and Other Respiratory Viruses (via https://onlinelibrary.wiley.com/doi/10.1111/irv.70162)
Bovine respiratory disease complex (BRDC) is a major disease problem in cattle production systems. Numerous pathogens have been implicated as causing BRDC, including the recently discovered influenza D ... Qiao Y, Tang M, Du M, Zhao C, Lv Y, Zhou J, Liu Y,. H5N1 influenza virus-like particles based on BEVS induce robust functional antibodies and immune responses. Virology. 2025 Aug 29;612:110672. Abstract
submitted by kickingbird at Sep, 9, 2025 from Virology. 2025 Aug 29;612:110672 (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Avian influenza virus infections pose a potential pandemic threat. The currently licensed vaccines have inherent limitations, emphasizing the urgent need for improved influenza vaccines. Here, we developed ... Chloe Stenkamp-Strahm, etc.,al. [preprint]Dairy Environments with Milk Exposure are Most Likely to Have Detection of Influenza A Virus. https://doi.org/10.1101/2025.09.03.25335023. Abstract
submitted by kickingbird at Sep, 9, 2025 from https://doi.org/10.1101/2025.09.03.25335023 (via https://www.medrxiv.org/content/10.1101/2025.09.03.25335023v)
Highly pathogenic avian influenza virus of the H5N1 subtype has been infecting U.S dairy cattle and spreading among dairy farms since March 2024. H5N1 surveillance systems for dairy farms are needed, but ... Chen P-L, Yang G, Ojha C, Banoth B, Russell CJ. Modification of H1N1 Influenza Luciferase Reporter Viruses Using StopGo Translation and/or Mouse-Adapted Mutations. Viruses. 2025; 17(9):1211. Abstract
submitted by kickingbird at Sep, 8, 2025 from Viruses. 2025; 17(9):1211 (via https://www.mdpi.com/1999-4915/17/9/1211)
Reporter viruses are valuable tools for studying infections at the cellular level and in living animals. They also enable rapid, high-throughput antiviral drug screening and serological studies. We previously ... Asante IA, Asante-Ntim NA, Abankwa AA, Ofori OB, B. Characterization of the first detected Avian Influenza A(H9N2) human case in Ghana. Emerg Microbes Infect. 2025 Sep 3:2556717. Abstract
submitted by kickingbird at Sep, 6, 2025 from Emerg Microbes Infect. 2025 Sep 3:2556717 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Avian influenza A(H9N2) has been circulating in poultry across Asia, the Middle East, and Africa, posing human health risks. In Ghana, it has co-circulated among poultry with influenza A (H5N1). This report ... Xia Y, Yuan J, Liu T, Zhang R, Wu C, Sui N, Li L,. TRPM2 knockdown alleviated H9N2 influenza virus infected ferroptosis in mouse pulmonary microvascular endothelial cells. Vet Microbiol. 2025 Sep 1;310:110703. Abstract
submitted by kickingbird at Sep, 6, 2025 from Vet Microbiol. 2025 Sep 1;310:110703 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
H9N2 influenza virus, a prevalent influenza A virus, causes acute lung injury through mitochondrial damage associated with oxidative stress. Transient receptor potential melastatin 2 (TRPM2) is a Ca2+ ... Beckmen KB, Burek Huntington KA, Spraker T, Ellis. Pathologic Characterization of Highly Pathogenic H5N1 Avian Influenza Virus Infections in Wild Mammals in Alaska, USA. J Wildl Dis. 2025 Sep 5. Abstract
submitted by kickingbird at Sep, 6, 2025 from J Wildl Dis. 2025 Sep 5 (via https://meridian.allenpress.com/jwd/article/doi/10.7589/JWD-)
This report describes highly pathogenic avian influenza virus (HPAI) H5N1 infections in carnivores in Alaska, US between 2022 and 2024, including a black bear (Ursus americanus), a brown bear (Ursus arctos), ... Tobolowsky FA, Morris E, Castro L, Schaff T, Jacin. Highly Pathogenic Avian Influenza A(H5N1) Virus Infection in a Child with No Known Exposure - San Francisco, California, December 2024-January 2025. MMWR Morb Mortal Wkly Rep. 2025 Sep 4;74(33):522-5. Abstract
submitted by kickingbird at Sep, 5, 2025 from MMWR Morb Mortal Wkly Rep. 2025 Sep 4;74(33):522-5 (via https://www.cdc.gov/mmwr/volumes/74/wr/mm7433a2.htm?s_cid=mm)
In response to a highly pathogenic avian influenza (HPAI) A(H5N1) outbreak in U.S. dairy cows detected in March 2024, with subsequent identification of human cases, the San Francisco Department of Public ... Jordan T. Ort, etc.,al. [preprint]Cross-reactive human antibody responses to H5N1 influenza virus neuraminidase are shaped by immune history. https://doi.org/10.1101/2025.09.02.25334929. Abstract
submitted by kickingbird at Sep, 5, 2025 from https://doi.org/10.1101/2025.09.02.25334929 (via https://www.medrxiv.org/content/10.1101/2025.09.02.25334929v)
H5N1 highly pathogenic avian influenza viruses have spread globally and pose a risk for a human pandemic. Prior studies suggest that early life exposures to group 1 influenza viruses (H1N1 and H2N2) prime ... Rute Maria Pinto, etc.,al. [preprint]The cow udder is a potential mixing vessel for influenza A viruses. https://doi.org/10.1101/2025.08.29.673079. Abstract
submitted by kickingbird at Sep, 4, 2025 from https://doi.org/10.1101/2025.08.29.673079 (via https://www.biorxiv.org/content/10.1101/2025.08.29.673079v1)
The incursion of high pathogenicity avian influenza A virus (IAV) into US dairy cows is unprecedented in the era of molecular diagnosis and pathogen sequencing. This raises questions over the likelihood ... 9542 items, 20/Page, Page[20/478][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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