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2026-10-7 13:42:02
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Prantner D, Qi X, Villaneuva LM, Paton J, Blanco J. The signaling adaptor insulin receptor substrate 2 (IRS2) limits lethal host responses induced by influenza infection. Innate Immun. 2026 Jan-Dec;32:17534259261469305.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from Innate Immun. 2026 Jan-Dec;32:17534259261469305 (via https://journals.sagepub.com/doi/10.1177/17534259261469305)
Influenza is a highly contagious virus with most individuals showing recovery within a week after symptom onset. However, children, the elderly, and those with chronic health conditions are at high risk ...

Da Silva K, Naffakh N, Rameix-Welti MA, Lemoine F. Accounting for Defective Viral Genomes in viral consensus genome reconstruction, application to influenza virus. PLoS Comput Biol. 2026 Jul 16;22(7):e1014115.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from PLoS Comput Biol. 2026 Jul 16;22(7):e1014115 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
In the context of viral epidemic surveillance, generating accurate consensus viral genomes from sequencing data is critical for tracking the emergence of mutations of concern, evaluating the genomic diversity ...

Chen Y, Ankerhold J, Jia T, Wolkewitz M, Fuchs J,. Autoantibodies against type I interferons in patients with zoonotic H7N9 influenza: an observational case-control study. EBioMedicine. 2026 Jul 16;130:106387.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from EBioMedicine. 2026 Jul 16;130:106387 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: The determinants of the species barrier preventing human infections with avian influenza A viruses (IAV) are incompletely understood. We previously identified loss-of-function variants of the ...

Han Yan, etc.,al. [preprint]Antibodies against influenza A/H1N1pdm2009 and B/Victoria strains but not A/H3N2 are increased in recent onset type 1 narcolepsy versus matched controls. https://doi.org/10.64898/2026.06.13.26355596.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from https://doi.org/10.64898/2026.06.13.26355596 (via https://www.medrxiv.org/content/10.64898/2026.06.13.26355596)
Study Objectives Onsets of Narcolepsy type-1 (NT1) increased following A/H1N1 vaccination with Pandemrix? in Europe and with A/H1N1pdm2009 infections in China and other countries. To test if other strains ...

Ciminski K, Reuther P, Rijkers R, de Vries RP, Sch. The receptor landscape of influenza A viruses. J Virol 0:e01443-25.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from J Virol 0:e01443-25 (via https://journals.asm.org/doi/10.1128/jvi.01443-25)
Influenza A viruses (IAVs) have a remarkable ability to adapt to new host species, which has been attributed to the specificity of the viral hemagglutinin (HA) for sialylated glycans and the functional ...

Shirazi R, Kim SY, Cruz A, Stumpff JP, Sveiven SN,. RELMα establishes a permissive environment for influenza virus infection through direct effects on lung epithelial cells. J Virol 0:e02225-25.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from J Virol 0:e02225-25 (via https://journals.asm.org/doi/10.1128/jvi.02225-25)
Beyond a physical barrier, the lung epithelium provides an essential line of defense against infectious pathogens, such as influenza A viruses (IAVs), by producing antimicrobial factors and triggering ...

Kubacki J, Renzullo S, Miller-Collmann N, Lale D,. Genome sequence of a Florida Clade 1 case of equine influenza in Switzerland. Microbiol Resour Announc 0:e00635-26.  Abstract  
submitted by kickingbird at Jul, 17, 2026 from Microbiol Resour Announc 0:e00635-26 (via https://journals.asm.org/doi/10.1128/mra.00635-26)
Here, we report the whole-genome sequence of A/Equus caballus/Zuerich/260760/2026, an equine influenza virus (H3N8) belonging to Florida Clade 1, detected in Switzerland following increased reports of ...

Snyder CA, Janzen GM, Zanella GC, Moraes DCA, Silv. Occupationally Exposed and General Population Antibody Profiles to Influenza A Viruses Circulating in Swine as Indication of Zoonotic Risk. Emerg Infect Dis. 2026 Aug.  Abstract  
submitted by kickingbird at Jul, 16, 2026 from Emerg Infect Dis. 2026 Aug (via https://wwwnc.cdc.gov/eid/article/32/8/25-1995_article)
Persons with occupational exposure to swine might be at disproportionate risk for zoonotic swine influenza A virus. To evaluate human antibody responses, we tested serum or plasma from swine veterinarian, ...

Seger H, Baker AL, Buckley AC, Anderson TK, Markin. Detection of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Genotype D1.2 Virus in Swine after Experimental Inoculation. Emerg Infect Dis. 2026 Aug.  Abstract  
submitted by kickingbird at Jul, 16, 2026 from Emerg Infect Dis. 2026 Aug (via https://wwwnc.cdc.gov/eid/article/32/8/25-1765_article)
Highly pathogenic avian influenza H5NX clade 2.3.4.4b viruses continue to circulate globally. Reintroduction of Eurasian lineage viruses into North America and reassortment with endemic low pathogenicity ...

Pyles, K., Darling, T.L., Huang, LC. et al. Intranasal and intramuscular H5-Matrix-M nanoparticle vaccines protects against highly pathogenic H5N1 influenza virus in mice. npj Vaccines (2026).  Abstract  
submitted by kickingbird at Jul, 15, 2026 from npj Vaccines (2026) (via https://link.springer.com/article/10.1038/s41541-026-01523-8)
The emergence of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in dairy cows and transmission to humans has heightened public health concerns. In this work, we characterized the immunogenicity ...

Jiahao Zhang, Huaiyuan Cai, Tingting Man, Lihong H. Heterogeneous viral-host response at single-cell resolution and viral adaptive mutational atlas in birds and mammals upon H5 influenza virus infection. National Science Review, 2026;, nwag380.  Abstract  
submitted by kickingbird at Jul, 15, 2026 from National Science Review, 2026;, nwag380 (via https://academic.oup.com/nsr/advance-article/doi/10.1093/nsr)
H5 highly pathogenic avian influenza viruses (HPAIVs) are prevalent in birds, causing infection in over 60 mammalian species worldwide. However, species-specific viral-host response at the single-cell ...

Ren Y, Li H, Yan W, Liu X, Chi W, Luo R, Stoeger T. Novel Reassortant H9N2 Avian Influenza Viruses with Dual Receptor-Binding Capacity and Evidence of Direct Mammalian Infectivity Circulating in Northeast China Live Poultry Markets. Viruses. 2026; 18(7):771.  Abstract  
submitted by kickingbird at Jul, 15, 2026 from Viruses. 2026; 18(7):771 (via https://www.mdpi.com/1999-4915/18/7/771)
H9N2 low-pathogenic avian influenza viruses (LPAIV) represent an ongoing zoonotic threat due to their enzootic circulation in poultry, reassortment capacity, and increasing human transmission events. This ...

Higerd-Rusli GP, Hoffman SA, Karan A, Huang C, Sah. Validation of sample pooling for high-throughput RT-qPCR subtyping of avian influenza A(H5). Microbiol Spectr 0:e00850-26.  Abstract  
submitted by kickingbird at Jul, 15, 2026 from Microbiol Spectr 0:e00850-26 (via https://journals.asm.org/doi/10.1128/spectrum.00850-26)
Highly pathogenic avian influenza A(H5N1) is a global health threat due to its high historical virulence and increasing mammalian host range, as demonstrated by the 2024–2025 outbreak among U.S. dairy ...

Li, M., Cai, S., Chen, J. et al. Spatiotemporal epidemiology of influenza in Fujian Province: an 18-year observational study. BMC Infect Dis (2026).  Abstract  
submitted by kickingbird at Jul, 15, 2026 from BMC Infect Dis (2026) (via https://link.springer.com/article/10.1186/s12879-026-13938-8)
ObjectiveTo investigate the spatiotemporal epidemiological characteristics and temporal trends of influenza in Fujian Province, China, from 2005 to 2022.MethodsDescriptive epidemiological methods were ...

Li, Z. et al. (2027). A Unified Benchmark and Conditional Sequence Modeling Framework for Future Influenza Evolution Prediction. ISBRA 2026. Lecture Notes in Computer Science.  Abstract  
submitted by kickingbird at Jul, 15, 2026 from ISBRA 2026. Lecture Notes in Computer Science (via https://link.springer.com/chapter/10.1007/978-981-92-3716-6_)
Vaccination remains the most effective strategy for seasonal influenza prevention, but vaccine strain selection depends on anticipating future circulating variants before they are fully observed. This ...

Takadate Y, Nishiura H, Kumagai A, Mine J, Tsuneku. High pathogenicity avian influenza A (H5N1) viruses isolated from poultry and wild birds in Japan during the 2024-2025 season. Microbiol Spectr. 2026 Jul 14:e0029326.  Abstract  
submitted by kickingbird at Jul, 15, 2026 from Microbiol Spectr. 2026 Jul 14:e0029326 (via https://journals.asm.org/doi/10.1128/spectrum.00293-26)
H5N1 high pathogenicity avian influenza (HPAI) viruses of clade 2.3.4.4b continue to spread globally among wild birds and poultry, and diversify through gene reassortment. Since 2024, spillovers of H5N1 ...

Mirolo M, Ludlow M, Osterhaus A. Mass mortality events in aquatic mammals caused by avian influenza viruses. Curr Opin Virol. 2026 Jul 13;77:101566.  Abstract  
submitted by kickingbird at Jul, 15, 2026 from Curr Opin Virol. 2026 Jul 13;77:101566 (via https://www.sciencedirect.com/science/article/pii/S187962572)
In recent decades, mass mortality events (MMEs) among aquatic mammals have been caused by morbillivirus or avian influenza virus (AIV) infections. Thus far, AIV infections have been predominantly associated ...

Scotch M, Faleye TOC, Urquidez-Negrete A, Varsani. Rapid Expansion of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Genotype D1.1 Virus across Flyway Regions, North America, Fall 2024. Emerg Infect Dis. 2026 Aug.  Abstract  
submitted by kickingbird at Jul, 14, 2026 from Emerg Infect Dis. 2026 Aug (via https://wwwnc.cdc.gov/eid/article/32/8/26-0205_article)
Highly pathogenic avian influenza clade 2.3.4.4b virus continues to circulate in North America and has caused severe human disease. That clade includes genotype D1.1, which became dominant in birds in ...

Zhang, X., Tang, Q., Zhang, Y. et al. Divergent pathogenic mechanisms of influenza A and influenza B viruses. Arch Microbiol 208, 476 (2026).  Abstract  
submitted by kickingbird at Jul, 13, 2026 from Arch Microbiol 208, 476 (2026) (via https://link.springer.com/article/10.1007/s00203-026-05032-z)
Seasonal influenza in humans is predominantly caused by influenza A virus (IAV) and influenza B virus (IBV), but they differ markedly in host range, evolutionary dynamics, and pandemic potential. Such ...

Pyles, K., Darling, T.L., Huang, LC. et al. Intranasal and intramuscular H5-Matrix-M nanoparticle vaccines protects against highly pathogenic H5N1 influenza virus in mice. npj Vaccines (2026).  Abstract  
submitted by kickingbird at Jul, 13, 2026 from npj Vaccines (2026) (via https://link.springer.com/article/10.1038/s41541-026-01523-8)
The emergence of clade 2.3.4.4b highly pathogenic H5N1 influenza virus in dairy cows and transmission to humans has heightened public health concerns. In this work, we characterized the immunogenicity ...

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