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2024-5-18 17:53:38
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Hayden FG. et al. Baloxavir Marboxil for Uncomplicated Influenza in Adults and Adolescents. N Engl J Med. 2018 Sep 6;379(10):913-923.  Abstract  
submitted by kickingbird at Oct, 10, 2018 from N Engl J Med. 2018 Sep 6;379(10):913-923 (via https://www.nejm.org/doi/full/10.1056/NEJMoa1716197)
BackgroundBaloxavir marboxil is a selective inhibitor of influenza cap-dependent endonuclease. It has shown therapeutic activity in preclinical models of influenza A and B virus infections, including strains ...

Steve G.Robison, Ann R.Thomas. Assessing the effectiveness of high-dose influenza vaccine in preventing hospitalization among seniors, and observations on the limitations of effectiveness study design. Vaccine 1 October 2018.  Abstract  
submitted by kickingbird at Oct, 9, 2018 from Vaccine 1 October 2018 (via https://www.sciencedirect.com/science/article/pii/S0264410X1)
BackgroundThe availability of high-dose (HD) influenza vaccine for seniors should decrease influenza-related hospitalization. Studies to date show a range of mostly moderate increased HD vaccine effectiveness ...

Chang P, Sealy JE, Sadeyen JR, Iqbal M. Amino acid residue 217 in the hemagglutinin glycoprotein is a key mediator of avian influenza H7N9 virus antigenicity. J Virol. 2018 Oct 3. pii: JVI.01627-18.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from J Virol. 2018 Oct 3. pii: JVI.01627-18 (via https://www.ncbi.nlm.nih.gov/pubmed/30282714)
Avian influenza viruses continue to evolve and acquire mutations that facilitate antigenic drift and virulence change. In 2017, low pathogenicity H7N9 avian influenza viruses evolved to a high pathogenicity ...

Wang S, etc.,al. Identification of two residues within the NS1 of H7N9 influenza A virus that critically affect the protein stability and function. Vet Res. 2018 Oct 1;49(1):98.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Vet Res. 2018 Oct 1;49(1):98 (via https://www.ncbi.nlm.nih.gov/pubmed/30285871)
The emerging avian-origin H7N9 influenza A virus, which causes mild to lethal human respiratory disease, continues to circulate in China, posing a great threat to public health. Influenza NS1 protein plays ...

Young B, etc.,al. Six-monthly versus annual influenza vaccination in older adults in the tropics: an observer-blind, active-comparator controlled, randomised superiority trial. Clin Infect Dis. 2018 Oct 1..  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Clin Infect Dis. 2018 Oct 1. (via https://www.ncbi.nlm.nih.gov/pubmed/30277500)
Background: Antibody titres and vaccine effectiveness decline within six months after influenza vaccination in older adults. Biannual vaccination may be necessary to provide year-round protection in the ...

Shanks GD. The ´Influenza´ Vaccine Used during the Samoan Pandemic of 1918. Trop Med Infect Dis. 2018 Feb 2;3(1).  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Trop Med Infect Dis. 2018 Feb 2;3(1) (via https://www.ncbi.nlm.nih.gov/pubmed/30274415)
In 1918, a crude influenza vaccine made from chemically inactivated, mixed cultures of respiratory bacteria was widely used prior to the understanding that influenza was caused by a virus. Such vaccines ...

Hayashi T, etc.,al. Impact of early life exposure to ionizing radiation on influenza vaccine response in an elderly Japanese cohort. Vaccine. 2018 Sep 28.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Vaccine. 2018 Sep 28 (via https://www.ncbi.nlm.nih.gov/pubmed/30274868)
The objective of this study was to evaluate effects of whole body radiation exposure early in life on influenza vaccination immune responses much later in life. A total of 292 volunteers recruited from ...

Mirzaei SG, Shoushtari A, Nouri A. Development and Evaluation of Real-Time RT-PCR Test for Quantitative and Qualitative Recognition of Current H9N2 Subtype Avian Influenza Viruses in Iran. Arch Razi Inst. 2018 Sep;73(3):177-182.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Arch Razi Inst. 2018 Sep;73(3):177-182 (via https://www.ncbi.nlm.nih.gov/pubmed/30280837)
Avian influenza H9N2 subtype viruses have had a great impact on Iranian industrial poultry production economy since introduction in the country. To approach Rapid and precise identification of this viruses ...

Hatayama K, etc.,al. Combined effect of anti-high-mobility group box-1 monoclonal antibody and peramivir against influenza A virus-induced pneumonia in mice. J Med Virol. 2018 Oct 3.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from J Med Virol. 2018 Oct 3 (via https://www.ncbi.nlm.nih.gov/pubmed/30281823)
Human pandemic H1N1 2009 influenza virus causes significant morbidity and mortality with severe acute lung injury (ALI) due to excessive inflammatory reaction, even with neuraminidase inhibitor use. The ...

Okamoto M, etc.,al. MicroRNA-451a in extracellular, blood-resident vesicles attenuates macrophage and dendritic cell responses to influenza whole-virus vaccine. J Biol Chem. 2018 Oct 3..  Abstract  
submitted by kickingbird at Oct, 6, 2018 from J Biol Chem. 2018 Oct 3. (via https://www.ncbi.nlm.nih.gov/pubmed/30282637)
The innate immune system is important for the efficacy of vaccines, but excessive innate immune responses can cause adverse reactions after vaccination. Extracellular vesicles (EVs) are enriched in the ...

Fay EJ, etc.,al. Engineered small molecule control of influenza A virus replication. J Virol. 2018 Oct 3..  Abstract  
submitted by kickingbird at Oct, 6, 2018 from J Virol. 2018 Oct 3. (via https://www.ncbi.nlm.nih.gov/pubmed/30282710)
Influenza A virus (IAV) remains a global health concern despite the availability of a seasonal vaccine. It is difficult to predict which strains will circulate during influenza season, and therefore extremely ...

Jang Y, etc.,al. Salinomycin Inhibits Influenza Virus Infection by Disrupting Endosomal Acidification and Viral Matrix Protein 2 Function. J Virol. 2018 Oct 3.  Abstract  
submitted by kickingbird at Oct, 6, 2018 from J Virol. 2018 Oct 3 (via https://www.ncbi.nlm.nih.gov/pubmed/30282713)
Screening of chemical libraries with 2,000 synthetic compounds identified salinomycin as a hit against influenza A and B viruses with 50% effective concentrations ranging from 0.4 to 4.3 μM in cells. This ...

Lee JJ, etc.,al. The clinical utility of point-of-care tests for influenza in ambulatory care: A systematic review and meta-analysis. Clin Infect Dis. 2018 Oct 4..  Abstract  
submitted by kickingbird at Oct, 6, 2018 from Clin Infect Dis. 2018 Oct 4. (via https://www.ncbi.nlm.nih.gov/pubmed/30285232)
Background: Point-of-care tests (POCTs) for influenza are diagnostically superior to clinical diagnosis, but their impact on patient outcomes is unclear.Methods: A systematic review of influenza POCTs ...

Trinh P, etc.,al. Temporal and spatial associations between influenza and asthma hospitalisations in New York City from 2002 to 2012: a longitudinal ecological study. BMJ Open. 2018 Sep 28;8(9):e020362..  Abstract  
submitted by kickingbird at Oct, 3, 2018 from BMJ Open. 2018 Sep 28;8(9):e020362. (via https://www.ncbi.nlm.nih.gov/pubmed/30269061)
OBJECTIVES: To determine whether asthma hospitalisations of children and adults in the five boroughs of New York City are correlated with influenza hospitalisations temporally and spatially.DESIGN: A longitudinal ...

Reid SM, etc.,al. Detection of non-notifiable H4N6 avian influenza virus in poultry in Great Britain. Vet Microbiol. 2018 Oct;224:107-115..  Abstract  
submitted by kickingbird at Oct, 3, 2018 from Vet Microbiol. 2018 Oct;224:107-115. (via https://www.ncbi.nlm.nih.gov/pubmed/30269784)
A 12-month pilot project for notifiable avian disease (NAD) exclusion testing in chicken and turkey flocks in Great Britain (GB) offered, in partnership with industry, opportunities to carry out differential ...

Srivastav A, O´Halloran A, Lu PJ, Williams W. Influenza Vaccination Coverage Among English-Speaking Asian Americans. Am J Prev Med. 2018 Sep 19.  Abstract  
submitted by kickingbird at Oct, 3, 2018 from Am J Prev Med. 2018 Sep 19 (via https://www.ncbi.nlm.nih.gov/pubmed/30262150)
INTRODUCTION: English-speaking non-Hispanic Asians (Asians) in the U.S. include populations with multiple geographic origins and ethnicities (e.g., Asian Indian, Chinese, Filipino, Japanese, Korean, and ...

Yamazaki W, Makino R, Nagao K, etc.,al. New Micro-amount of Virion Enrichment Technique (MiVET) to Detect Influenza A Virus in the Duck Feces. Transbound Emerg Dis. 2018 Sep 29.  Abstract  
submitted by kickingbird at Oct, 3, 2018 from Transbound Emerg Dis. 2018 Sep 29 (via https://www.ncbi.nlm.nih.gov/pubmed/30267611)
Transboundary animal diseases, including highly pathogenic avian influenza, cause vast economic losses throughout the world. While it is important to identify the sources and propagation routes of the ...

Ogasawara K. The long-run effects of pandemic influenza on the development of children from elite backgrounds: Evidence from industrializing Japan. Econ Hum Biol. 2018 Sep 1;31:125-137..  Abstract  
submitted by kickingbird at Oct, 3, 2018 from Econ Hum Biol. 2018 Sep 1;31:125-137. (via https://www.ncbi.nlm.nih.gov/pubmed/30265896)
his study estimates the lingering effects of fetal exposure to the 1918 influenza pandemic on the development of secondary school and girls' high school students in industrializing Japan. In order to refine ...

Kavunga-Membo H, etc.,al. Epidemiology of circulating human influenza viruses from the Democratic Republic of Congo, 2015. PLoS One. 2018 Sep 28;13(9):e0203995.  Abstract  
submitted by kickingbird at Oct, 3, 2018 from PLoS One. 2018 Sep 28;13(9):e0203995 (via https://www.ncbi.nlm.nih.gov/pubmed/30265699)
INTRODUCTION: The establishment of the influenza sentinel surveillance system in Kinshasa, Bas Congo, Maniema, Katanga, and Kasai Provinces allowed generation of important data on the molecular epidemiology ...

Strohmidel P, Sperling M, Karst U. Investigations on the binding of ethylmercury from thiomersal to proteins in influenza vaccines. J Trace Elem Med Biol. 2018 Dec;50:100-104.  Abstract  
submitted by kickingbird at Oct, 3, 2018 from J Trace Elem Med Biol. 2018 Dec;50:100-104 (via https://www.ncbi.nlm.nih.gov/pubmed/30262265)
This study investigates the binding of ethylmercury (EtHg+) released from the preservative thiomersal by hydrolysis to proteins in influenza vaccines via ultrafiltration and subsequent total reflection ...

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