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2025-12-6 4:25:36
Article

Spackman E, Pantin-Jackwood MJ, Sitaras I, Stephen. Identification of Efficacious Vaccines Against Contemporary North American H7 Avian Influenza Viruses. Avian Dis. 2021 Mar;65(1):113-121.  Abstract  
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):113-121 (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
Five vaccines, including four inactivated, whole-virus water-in-oil adjuvanted vaccines and a commercial nonreplicating alphavirus-vectored RNA particle (RP) vaccine were evaluated in chickens for their ...

Wang Y, Chen X, Yuan Y. Antibody Response of an H9 Subtype Avian Influenza Poultry Vaccine on Three Kinds of Wild Birds in Shanghai Zoo. Avian Dis. 2021 Mar;65(1):90-94.  Abstract  
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):90-94 (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
A semiannual immunization with a commercial inactivated H9 subtype avian influenza virus (AIV) vaccine developed for poultry has been used to prevent and control the avian influenza (AI) infections among ...

Lee DH, Killian ML, Deliberto TJ, Wan XF, Lei L, S. H7N1 Low Pathogenicity Avian Influenza Viruses in Poultry in the United States During 2018. Avian Dis. 2021 Mar;65(1):59-62..  Abstract  
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):59-62. (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
Here, we report three detections of H7N1 low pathogenicity avian influenza viruses (LPAIV) from poultry in Missouri (n = 2) and Texas (n = 1) during February and March 2018. Complete genome sequencing ...

Fellahi S, Nassik S, Maaroufi I, Tligui NS, Touzan. Pathogenesis of Avian Influenza Virus Subtype H9N2 in Turkeys and Evaluation of Inactivated Vaccine Efficacy. Avian Dis. 2021 Mar;65(1):46-51.  Abstract  
submitted by kickingbird at Aug, 3, 2021 from Avian Dis. 2021 Mar;65(1):46-51 (via https://bioone.org/journals/avian-diseases/volume-65/issue-1)
Avian influenza H9N2 viruses circulate in all types of poultry species, including turkeys, and cause significant losses for the poultry industry in many parts of the word. The aim of this study was to ...

Sangsiriwut K, Noisumdaeng P, Uiprasertkul M, Pras. Full Genomic Sequences of H5N1 Highly Pathogenic Avian Influenza Virus in Human Autopsy Specimens Reveal Genetic Variability and Adaptive Changes for Growth in MDCK Cell Cultures. Biomed Res Int. 2021 Jul 22;2021:3890681.  Abstract  
submitted by kickingbird at Aug, 3, 2021 from Biomed Res Int. 2021 Jul 22;2021:3890681 (via https://www.hindawi.com/journals/bmri/2021/3890681/)
The entire H5N1 highly pathogenic avian influenza viral genomes were identified in the frozen autopsy specimens: the trachea, lung, colon, and intestinal feces from a patient who died of the disease in ...

Nudelman I, Kudrin D, Nudelman G, Deshpande R, Har. Comparing Host Module Activation Patterns and Temporal Dynamics in Infection by Influenza H1N1 Viruses. Front Immunol. 2021 Jul 14;12:691758..  Abstract  
submitted by kickingbird at Aug, 2, 2021 from Front Immunol. 2021 Jul 14;12:691758. (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.6917)
Influenza is a serious global health threat that shows varying pathogenicity among different virus strains. Understanding similarities and differences among activated functional pathways in the host responses ...

Hernandez-Davies JE, Felgner J, Strohmeier S, Pone. Administration of Multivalent Influenza Virus Recombinant Hemagglutinin Vaccine in Combination-Adjuvant Elicits Broad Reactivity Beyond the Vaccine Components. Front Immunol. 2021 Jul 14;12:692151..  Abstract  
submitted by kickingbird at Aug, 2, 2021 from Front Immunol. 2021 Jul 14;12:692151. (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.6921)
Combining variant antigens into a multivalent vaccine is a traditional approach used to provide broad coverage against antigenically variable pathogens, such as polio, human papilloma and influenza viruses. ...

Mamontov A, Losev I, Korzhevskii D, Guselnikova V,. Study of Antibody-Dependent Reactions of Mast Cells In Vitro and in a Model of Severe Influenza Infection in Mice. Front Immunol. 2021 Jul 14;12:689436..  Abstract  
submitted by kickingbird at Aug, 2, 2021 from Front Immunol. 2021 Jul 14;12:689436. (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.6894)
We investigated the reaction of mouse peritoneal mast cells (MCs) in vitro after IgG-containing immune complex introduction using A/H5N1 and A/H1N1pdm09 influenza viruses as antigens. The sera of immune ...

Trifkovic S, Gilbertson B, Fairmaid E, Cobbin J, R. Gene Segment Interactions Can Drive the Emergence of Dominant Yet Suboptimal Gene Constellations During Influenza Virus Reassortment. Front Microbiol. 2021 Jul 14;12:683152.  Abstract  
submitted by kickingbird at Aug, 2, 2021 from Front Microbiol. 2021 Jul 14;12:683152 (via https://www.frontiersin.org/articles/10.3389/fmicb.2021.6831)
A segmented genome enables influenza virus to undergo reassortment when two viruses infect the same cell. Although reassortment is involved in the creation of pandemic influenza strains and is routinely ...

Lee K, Pusterla N, Barnum SM, Lee DH, Martínez-Lóp. Genome-informed characterization of antigenic drift in the hemagglutinin gene of equine influenza strains circulating in the United States from 2012 to 2017. Transbound Emerg Dis. 2021 Jul 31.  Abstract  
submitted by kickingbird at Aug, 2, 2021 from Transbound Emerg Dis. 2021 Jul 31 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14262)
Equine influenza virus (EIV) is a major infectious pathogen causing significant respiratory signs in equids worldwide. Voluntary surveillances in the United States (US) recently reported EIV detection ...

Dylag AM, Haak J, Warren R, Yee M, Pryhuber GS, O&. Low Dose Hyperoxia Primes Airways for Fibrosis in Mice after Influenza A Infection. Am J Physiol Lung Cell Mol Physiol. 2021 Jul 29.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from Am J Physiol Lung Cell Mol Physiol. 2021 Jul 29 (via https://journals.physiology.org/doi/abs/10.1152/ajplung.0028)
It is well known that supplemental oxygen used to treat preterm infants in respiratory distress is associated with permanently disrupting lung development and the host response to influenza A virus (IAV). ...

Hall JS, Grear DA, Krauss S, Seiler JP, Dusek RJ,. Highly pathogenic avian influenza virus H5N2 (clade 2.3.4.4) challenge of mallards age appropriate to the 2015 midwestern poultry outbreak. Influenza Other Respir Viruses. 2021 Jul 29.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from Influenza Other Respir Viruses. 2021 Jul 29 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12886)
Background: The 2015 highly pathogenic avian influenza virus (HPAIV) H5N2 clade 2.3.4.4 outbreak in upper midwestern U.S. poultry operations was not detected in wild birds to any great degree during the ...

Chen L, Zhou S, Bao L, Millman AJ, Zhang Z, Wang Y. Incidence rates of influenza illness during pregnancy in Suzhou, China, 2015-2018. Influenza Other Respir Viruses. 2021 Jul 29.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from Influenza Other Respir Viruses. 2021 Jul 29 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.12888)
Background: Data on influenza incidence during pregnancy in China are limited.Methods: From October 2015 to September 2018, we conducted active surveillance for acute respiratory illness (ARI) among women ...

Eiden J, Volckaert B, Rudenko O, Aitchison R, Herb. Single Replication M2SR Influenza Vaccine Induced Immune Responses Associated with Protection Against Human Challenge with Highly Drifted H3N2 Influenza Strain. J Infect Dis. 2021 Jul 29:jiab374.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from J Infect Dis. 2021 Jul 29:jiab374 (via https://academic.oup.com/jid/advance-article/doi/10.1093/inf)
Background: Current influenza vaccines are strain-specific and demonstrate low vaccine efficacy against H3N2 influenza disease, especially when vaccine is mis-matched to circulating virus. The novel influenza ...

Al Saud AA, Goldsmith AJ, Schulwolf S, Almulhim A,. Ultrasound and Influenza: The Spectrum of Lung and Cardiac Ultrasound Findings in Patients with Suspected Influenza A and B. Ultrasound Med Biol. 2021 Jul 26:S0301-5629(21)002.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from Ultrasound Med Biol. 2021 Jul 26:S0301-5629(21)002 (via https://pubmed.ncbi.nlm.nih.gov/34325957/)
In patients with influenza, cardiac and lung ultrasound may help determine the severity of illness and predict clinical outcomes. To determine the ultrasound characteristics of influenza and define the ...

Chen J, Wang J, Zhang J, Ly H. Advances in Development and Application of Influenza Vaccines. Front Immunol. 2021 Jul 13;12:711997.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from Front Immunol. 2021 Jul 13;12:711997 (via https://www.frontiersin.org/articles/10.3389/fimmu.2021.7119)
Influenza A virus is one of the most important zoonotic pathogens that can cause severe symptoms and has the potential to cause high number of deaths and great economic loss. Vaccination is still the best ...

Ngunjiri JM, Taylor KJM, Ji H, Abundo MC, Ghorbani. Influenza A virus infection in turkeys induces respiratory and enteric bacterial dysbiosis correlating with cytokine gene expression. PeerJ. 2021 Jul 22;9:e11806.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from PeerJ. 2021 Jul 22;9:e11806 (via https://peerj.com/articles/11806/)
Turkey respiratory and gut microbiota play important roles in promoting health and production performance. Loss of microbiota homeostasis due to pathogen infection can worsen the disease or predispose ...

El Zowalaty ME, Abdelgadir A, Borkenhagen LK, Duca. Influenza a viruses are likely highly prevalent on South African Swine Farms. Transbound Emerg Dis. 2021 Jul 29.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from Transbound Emerg Dis. 2021 Jul 29 (via https://onlinelibrary.wiley.com/doi/10.1111/tbed.14255)
Growth in pork production during the last decade in South Africa has escalated the risk of zoonotic pathogen emergence. This cross-sectional study was conducted to evaluate evidence for cross-species transmission ...

Depelsenaire ACI, Witham K, Veitch M, Wells JW, An. Cellular responses at the application site of a high-density microarray patch delivering an influenza vaccine in a randomized, controlled phase I clinical trial. PLoS One. 2021 Jul 30;16(7):e0255282.  Abstract  
submitted by kickingbird at Jul, 31, 2021 from PLoS One. 2021 Jul 30;16(7):e0255282 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Microarray patches (MAPs) have the potential to be a safer, more acceptable, easier to use and more cost-effective method for administration of vaccines when compared to the needle and syringe. Since MAPs ...

Bestle D, Limburg H, Kruhl D, Harbig A, Stein DA,. Hemagglutinins of avian influenza viruses are proteolytically activated by TMPRSS2 in human and murine airway cells. J Virol. 2021 Jul 28:JVI0090621.  Abstract  
submitted by kickingbird at Jul, 29, 2021 from J Virol. 2021 Jul 28:JVI0090621 (via https://journals.asm.org/doi/10.1128/JVI.00906-21)
Cleavage of the influenza A virus (IAV) hemagglutinin (HA) by host proteases is indispensable for virus replication. Most IAVs possess a monobasic HA cleavage site cleaved by trypsin-like proteases. Previously, ...

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