Wang Z, Li H, Li Y, Wu Z, Ai H, Zhang M, Rong L, B. Mixed selling of different poultry species facilitates emergence of public-health-threating avian influenza viruses. Emerg Microbes Infect. 2023 May 16:2214255. Abstract
submitted by kickingbird at May, 17, 2023 from Emerg Microbes Infect. 2023 May 16:2214255 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2023.2)
Live poultry markets (LPMs) are regarded as hubs for avian influenza virus (AIV) transmission in poultry and are a major risk factor in human AIV infections. We performed an AIV surveillance study at a ... Islam A, Islam S, Flora MS, Amin E, Woodard K, Web. Epidemiology and molecular characterization of avian influenza A viruses H5N1 and H3N8 subtypes in poultry farms and live bird markets in Bangladesh. Sci Rep. 2023 May 16;13(1):7912. Abstract
submitted by kickingbird at May, 17, 2023 from Sci Rep. 2023 May 16;13(1):7912 (via https://www.nature.com/articles/s41598-023-33814-8)
Avian influenza virus (AIV) remains a global threat, with waterfowl serving as the primary reservoir from which viruses spread to other hosts. Highly pathogenic avian influenza (HPAI) H5 viruses continue ... Mazel-Sanchez B, Niu C, Williams N, Bachmann M, Ch. Influenza A virus exploits transferrin receptor recycling to enter host cells. Proc Natl Acad Sci U S A. 2023 May 23;120(21):e221. Abstract
submitted by kickingbird at May, 17, 2023 from Proc Natl Acad Sci U S A. 2023 May 23;120(21):e221 (via https://www.pnas.org/doi/10.1073/pnas.2214936120)
Influenza A virus (IAV) enters host cells mostly through clathrin-dependent receptor-mediated endocytosis. A single bona fide entry receptor protein supporting this entry mechanism remains elusive. Here ... Lopez-Moreno G, Culhane MR, Davies P, Corzo C, All. Farm management practices associated with influenza A virus contamination of people working in Midwestern United States swine farms. Porcine Health Manag. 2023 May 15;9(1):13. Abstract
submitted by kickingbird at May, 16, 2023 from Porcine Health Manag. 2023 May 15;9(1):13 (via https://porcinehealthmanagement.biomedcentral.com/articles/1)
Indirect transmission of influenza A virus (IAV) contributes to virus spread in pigs. To identify farm management activities with the ability to contaminate farmworkers' hands and clothing that then could ... Zhang L, Wang Y, Shao Y, Guo J, Gao GF, Deng T. Fine Regulation of Influenza Virus RNA Transcription and Replication by Stoichiometric Changes in Viral NS1 and NS2 Proteins. J Virol. 2023 May 11:e0033723. Abstract
submitted by kickingbird at May, 12, 2023 from J Virol. 2023 May 11:e0033723 (via https://journals.asm.org/doi/10.1128/jvi.00337-23)
In the influenza virus life cycle, viral RNA (vRNA) transcription (vRNA→mRNA) and replication (vRNA→cRNA→vRNA), catalyzed by the viral RNA-dependent RNA polymerase in the host cell nucleus, are delicately ... James J, Billington E, Warren CJ, De Sliva D, Di G. Clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus (HPAIV) from the 2021/22 epizootic is highly duck adapted and poorly adapted to chickens. J Gen Virol. 2023 May;104(5).. Abstract
submitted by kickingbird at May, 12, 2023 from J Gen Virol. 2023 May;104(5). (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
The 2021/2022 epizootic of high pathogenicity avian influenza (HPAIV) remains one of the largest ever in the UK, being caused by a clade 2.3.4.4b H5N1 HPAIV. This epizootic affected more than 145 poultry ... Lin X, Zhu M, Zhao X, Si L, Dong M, Anirudhan V, C. Optimization and applications of an in vivo bioluminescence imaging model of influenza a virus infections. Virol Sin. 2023 May 2:S1995-820X(23)00045-7. Abstract
submitted by kickingbird at May, 8, 2023 from Virol Sin. 2023 May 2:S1995-820X(23)00045-7 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Highlights?The in vivo BLI model of IAV infections can simplify the determination of viral load in living animals.?The in vivo BLI model of IAV infections allow longitudinal measurements of virus infection/spread ... Fernández-Díaz M, Villanueva-Pérez D, Tataje-Lavan. Detection and Genomic Characterization of an Avian Influenza Virus Subtype H5N1 (Clade 2.3.4.4b) Strain Isolated from a Pelican in Peru. Microbiol Resour Announc. 2023 May 1:e0019923. Abstract
submitted by kickingbird at May, 4, 2023 from Microbiol Resour Announc. 2023 May 1:e0019923 (via https://journals.asm.org/doi/10.1128/mra.00199-23)
Surveillance helps us identify and monitor strains with zoonotic potential. A tracheal swab from a pelican on a Peruvian beach was H5N1 positive (clade 2.3.4.4b) using Oxford Nanopore's MinION platform. ... Rumfelt KE, Fitzsimmons WJ, Truscon R, Monto AS, M. A rapid and flexible microneutralization assay for serological assessment of influenza viruses. Influenza Other Respir Viruses. 2023;17(4):e13141. Abstract
submitted by kickingbird at May, 4, 2023 from Influenza Other Respir Viruses. 2023;17(4):e13141 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13141)
Background: Serological responses from influenza vaccination or infection are typically measured by hemagglutinin inhibition (HAI) or microneutralization (MN). Both methods are limited in feasibility, ... Zhu AQ, Li ZJ, Zhang HJ. Spatial timing of circulating seasonal influenza A and B viruses in China from 2014 to 2018. Sci Rep. 2023 May 2;13(1):7149. Abstract
submitted by kickingbird at May, 4, 2023 from Sci Rep. 2023 May 2;13(1):7149 (via https://www.nature.com/articles/s41598-023-33726-7)
Major outbreaks of influenza virus occurred in China in 2017-2018. To describe the pattern of influenza circulation and timing of seasonal epidemics, we analyzed data from influenza-like illness (ILI) ... Mirska B, Wo?niak T, Lorent D, Ruszkowska A, Peter. In vivo secondary structural analysis of Influenza A virus genomic RNA. Cell Mol Life Sci. 2023 May 2;80(5):136. Abstract
submitted by kickingbird at May, 4, 2023 from Cell Mol Life Sci. 2023 May 2;80(5):136 (via https://link.springer.com/article/10.1007/s00018-023-04764-1)
Influenza A virus (IAV) is a respiratory virus that causes epidemics and pandemics. Knowledge of IAV RNA secondary structure in vivo is crucial for a better understanding of virus biology. Moreover, it ... Furness RW, Gear SC, Camphuysen KCJ, Tyler G, de S. Environmental Samples Test Negative for Avian Influenza Virus H5N1 Four Months after Mass Mortality at A Seabird Colony. Pathogens. 2023 Apr 12;12(4):584.. Abstract
submitted by kickingbird at May, 1, 2023 from Pathogens. 2023 Apr 12;12(4):584. (via https://www.mdpi.com/2076-0817/12/4/584)
High pathogenicity avian influenza (HPAI) profoundly impacted several seabird populations during the summers of 2021 and 2022. Infection spread rapidly across colonies, causing unprecedented mortality. ... Alvarez I, H?gglund S, N?slund K, Eriksson A, Ahlg. Detection of Influenza D-Specific Antibodies in Bulk Tank Milk from Swedish Dairy Farms. Viruses. 2023 Mar 24;15(4):829. Abstract
submitted by kickingbird at May, 1, 2023 from Viruses. 2023 Mar 24;15(4):829 (via https://www.mdpi.com/1999-4915/15/4/829)
Influenza D virus (IDV) has been detected in bovine respiratory disease (BRD) outbreaks, and experimental studies demonstrated this virus's capacity to cause lesions in the respiratory tract. In addition, ... Abdelwhab EM, Mettenleiter TC. Zoonotic Animal Influenza Virus and Potential Mixing Vessel Hosts. Viruses. 2023 Apr 16;15(4):980. Abstract
submitted by kickingbird at May, 1, 2023 from Viruses. 2023 Apr 16;15(4):980 (via https://www.mdpi.com/1999-4915/15/4/980)
Influenza viruses belong to the family Orthomyxoviridae with a negative-sense, single-stranded segmented RNA genome. They infect a wide range of animals, including humans. From 1918 to 2009, there were ... Ghafoori SM, Petersen GF, Conrady DG, Calhoun BM,. Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site. Sci Rep. 2023 Apr 28;13(1):6940. Abstract
submitted by kickingbird at May, 1, 2023 from Sci Rep. 2023 Apr 28;13(1):6940 (via https://www.nature.com/articles/s41598-023-33529-w)
Influenza virus (IV) causes several outbreaks of the flu each year resulting in an economic burden to the healthcare system in the billions of dollars. Several influenza pandemics have occurred during ... Liu L, Madhugiri R, Saul VV, Bacher S, Kracht M, P. Phosphorylation of the PA subunit of influenza polymerase at Y393 prevents binding of the 5´-termini of RNA and polymerase function. Sci Rep. 2023 Apr 29;13(1):7042. Abstract
submitted by kickingbird at May, 1, 2023 from Sci Rep. 2023 Apr 29;13(1):7042 (via https://www.nature.com/articles/s41598-023-34285-7)
The influenza A virus (IAV) polymerase is a multifunctional machine that can adopt alternative configurations to perform transcription and replication of the viral RNA genome in a temporally ordered manner. ... Guo Y, Sun T, Bai X, Liang B, Deng L, Zheng Y, Yu. Comprehensive analysis of the key amino acid substitutions in the polymerase and NP of avian influenza virus that enhance polymerase activity and affect adaptation to mammalian hosts. Vet Microbiol. 2023 Apr 25;282:109760. Abstract
submitted by kickingbird at May, 1, 2023 from Vet Microbiol. 2023 Apr 25;282:109760 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
Accumulation of adaptive mutations in the polymerase and NP genes is crucial for the adaptation of avian influenza A viruses (IAV) to a new host. Here, we identified residues in the polymerase and NP proteins ... Hui KPY, Ho JCW, Ng KC, Cheng SMS, Sit KY, Au TWK,. Replication of Novel Zoonotic-Like Influenza A(H3N8) Virus in Ex Vivo Human Bronchus and Lung. Emerg Infect Dis. 2023 Apr 24;29(6). Abstract
submitted by kickingbird at Apr, 27, 2023 from Emerg Infect Dis. 2023 Apr 24;29(6) (via https://pubmed.ncbi.nlm.nih.gov/37095078/)
Human infection with avian influenza A(H3N8) virus is uncommon but can lead to acute respiratory distress syndrome. In explant cultures of the human bronchus and lung, novel H3N8 virus showed limited replication ... Bruno A, Alfaro-Nú?ez A, de Mora D, Armas R, Olmed. Phylogenetic analysis reveals that the H5N1 avian influenza A outbreak in poultry in Ecuador in November 2022 is associated to the highly pathogenic clade 2.3.4.4b. Int J Infect Dis. 2023 Apr 20:S1201-9712(23)00533-. Abstract
submitted by kickingbird at Apr, 24, 2023 from Int J Infect Dis. 2023 Apr 20:S1201-9712(23)00533- (via https://www.ijidonline.com/article/S1201-9712(23)00533-7/ful)
The ongoing H5N1 outbreak in the Americas caused by clade 2.3.4.4, is causing unprecedented impact in poultry and wild birds. In November 2022, a highly pathogenic avian influenza A outbreak was declared ... Bhat P, Aksenova V, Gazzara M, Rex EA, Aslam S, Ha. Influenza virus mRNAs encode determinants for nuclear export via the cellular TREX-2 complex. Nat Commun. 2023 Apr 21;14(1):2304. Abstract
submitted by kickingbird at Apr, 24, 2023 from Nat Commun. 2023 Apr 21;14(1):2304 (via https://www.nature.com/articles/s41467-023-37911-0)
Nuclear export of influenza A virus (IAV) mRNAs occurs through the nuclear pore complex (NPC). Using the Auxin-Induced Degron (AID) system to rapidly degrade proteins, we show that among the nucleoporins ... 10272 items, 20/Page, Page[170/514][|<<] [|<] [161] [162] [163] [164] [165] [166] [167] [168] [169] [170] [>|] [>>|] |
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