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Nielsen J, et al. European all-cause excess and influenza-attributable mortality in the 2017/18 season: should the burden of influenza B be reconsidered?. Clin Microbiol Infect. 2019 Feb 18..  Abstract  
submitted by kickingbird at Feb, 24, 2019 from Clin Microbiol Infect. 2019 Feb 18. (via https://www.clinicalmicrobiologyandinfection.com/article/S11)
OBJECTIVES: Weekly monitoring of European all-cause excess mortality, the EuroMOMO network, observed high excess mortality during the influenza B/Yamagata dominated 2017/18 winter season, especially among ...

Njouom R, et al. Detection of Influenza C Virus Infection among Hospitalized Patients, Cameroon. Emerg Infect Dis. 2019 Mar;25(3):607-609.  Abstract  
submitted by kickingbird at Feb, 24, 2019 from Emerg Infect Dis. 2019 Mar;25(3):607-609 (via https://wwwnc.cdc.gov/eid/article/25/3/18-1213_article)
We report 3 cases of influenza C virus in children hospitalized with severe acute respiratory infection in Cameroon. Two of these case-patients had grave clinical manifestations, but all 3 recovered. The ...

Han L, et al. Smoking and influenza-associated morbidity and mortality: a systematic review and meta-analysis. Epidemiology. 2019 Feb 15.  Abstract  
submitted by kickingbird at Feb, 24, 2019 from Epidemiology. 2019 Feb 15 (via https://insights.ovid.com/crossref?an=00001648-900000000-985)
BACKGROUND: Although smoking has been recognized as risk factor for many respiratory diseases, its effects on influenza-associated morbidity and mortality remain controversial. We conducted a systematic ...

Thornton AC, et al. Human exposures to H5N6 Avian influenza, England, 2018. J Infect Dis. 2019 Feb 21.  Abstract  
submitted by kickingbird at Feb, 24, 2019 from J Infect Dis. 2019 Feb 21 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
The human risk following exposure to the European reassortant avian influenza A (H5N6) is unknown. We used routine data collected as part of public health follow-up to assess outcomes of individuals exposed ...

Byrd-Leotis L, et al. Influenza binds phosphorylated glycans from human lung. Sci Adv. 2019 Feb 13;5(2):eaav2554.  Abstract  
submitted by kickingbird at Feb, 24, 2019 from Sci Adv. 2019 Feb 13;5(2):eaav2554 (via http://advances.sciencemag.org/content/5/2/eaav2554)
Influenza A viruses can bind sialic acid-terminating glycan receptors, and species specificity is often correlated with sialic acid linkage with avian strains recognizing α2,3-linked sialylated glycans ...

Nieto A, et al. Mutation S110L of H1N1 Influenza Virus Hemagglutinin: A Potent Determinant of Attenuation in the Mouse Model. Front Immunol. 2019 Feb 6;10:132..  Abstract  
submitted by kickingbird at Feb, 24, 2019 from Front Immunol. 2019 Feb 6;10:132. (via https://www.ncbi.nlm.nih.gov/pubmed/30787926)
Characterization of a pandemic 2009 H1N1 influenza virus isolated from a fatal case patient (F-IAV), showed the presence of three different mutations; potential determinants of its high pathogenicity that ...

To EE, et al. Intranasal and epicutaneous administration of Toll-like receptor 7 (TLR7) agonists provides protection against influenza A virus-induced morbidity in mice. Sci Rep. 2019 Feb 20;9(1):2366.  Abstract  
submitted by kickingbird at Feb, 24, 2019 from Sci Rep. 2019 Feb 20;9(1):2366 (via https://www.nature.com/articles/s41598-019-38864-5)
Toll-like receptor 7 (TLR7) is a pattern recognition receptor that recognizes viral RNA following endocytosis of the virus and initiates a powerful immune response characterized by Type I IFN production ...

Meineke R, Rimmelzwaan GF, Elbahesh H. Influenza Virus Infections and Cellular Kinases. Viruses. 2019 Feb 20;11(2).  Abstract  
submitted by kickingbird at Feb, 24, 2019 from Viruses. 2019 Feb 20;11(2) (via https://www.mdpi.com/1999-4915/11/2/171)
Influenza A viruses (IAVs) are a major cause of respiratory illness and are responsible for yearly epidemics associated with more than 500,000 annual deaths globally. Novel IAVs may cause pandemic outbreaks ...

Turgeon N, et al. Design and Validation with Influenza A Virus of an Aerosol Transmission Chamber for Ferrets. Int J Environ Res Public Health. 2019 Feb 19;16(4).  Abstract  
submitted by kickingbird at Feb, 24, 2019 from Int J Environ Res Public Health. 2019 Feb 19;16(4) (via https://www.mdpi.com/1660-4601/16/4/609)
Background: The importance of aerosols in the spread of viruses like influenza is still a subject of debate. Indeed, most viruses can also be transmitted through direct contact and droplets. Therefore, ...

Kandula S, Shaman J. Near-term forecasts of influenza-like illness: An evaluation of autoregressive time series approaches. Epidemics. 2019 Jan 17.  Abstract  
submitted by kickingbird at Feb, 24, 2019 from Epidemics. 2019 Jan 17 (via https://www.ncbi.nlm.nih.gov/pubmed/30792135)
Seasonal influenza in the United States is estimated to cause 9-35 million illnesses annually, with resultant economic burden amounting to $47-$150 billion. Reliable real-time forecasts of influenza can ...

Lei N, et al. Molecular evolution of influenza B virus during 2011-2017 in Chaoyang, Beijing, suggesting the free influenza vaccine policy. Sci Rep. 2019 Feb 21;9(1):2432..  Abstract  
submitted by kickingbird at Feb, 24, 2019 from Sci Rep. 2019 Feb 21;9(1):2432. (via https://www.nature.com/articles/s41598-018-38105-1)
Two influenza B virus lineages, B/Victoria and B/Yamagata, are co-circulating in human population. While the two lineages are serologically distinct and TIV only contain one lineage. It is important to ...

Zhang W, et al. Genetic Evolution and Molecular Selection of the HE Gene of Influenza C Virus. Viruses. 2019 Feb 19;11(2).  Abstract  
submitted by kickingbird at Feb, 24, 2019 from Viruses. 2019 Feb 19;11(2) (via https://www.mdpi.com/1999-4915/11/2/167)
Influenza C virus (ICV) was first identified in humans and swine, but recently also in cattle, indicating a wider host range and potential threat to both the livestock industry and public health than was ...

Jiao H, et al. MicroRNA expression profiles from HEK293 cells expressing H5N1 avian influenza virus non-structural protein 1. Innate Immun. 2019 Feb;25(2):110-117.  Abstract  
submitted by kickingbird at Feb, 22, 2019 from Innate Immun. 2019 Feb;25(2):110-117 (via https://journals.sagepub.com/doi/full/10.1177/17534259198263)
H5N1 avian influenza poses a serious threat to the poultry industry and human health. Non-structural protein 1 (NS1) plays an important role in the replication and pathogenesis of avian influenza virus ...

Sambala EZ, Ndwandwe DE, Imaan LM, Wiysonge CS. Evaluation of influenza surveillance systems in sub-Saharan Africa: a systematic review protocol. BMJ Open. 2019 Jan 28;9(1):e023335..  Abstract  
submitted by kickingbird at Feb, 22, 2019 from BMJ Open. 2019 Jan 28;9(1):e023335. (via https://bmjopen.bmj.com/content/9/1/e023335.long)
INTRODUCTION: Influenza infrastructure systems are crucial for maintaining surveillance operations, and for mitigating and responding to the disease. The role of surveillance is to isolate and identify ...

Qiu Y, et al. Viral infection detection using metagenomics technology in six poultry farms of eastern China. PLoS One. 2019 Feb 20;14(2):e0211553.  Abstract  
submitted by kickingbird at Feb, 21, 2019 from PLoS One. 2019 Feb 20;14(2):e0211553 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
With rapidly increasing animal pathogen surveillance requirements, new technologies are needed for a comprehensive understanding of the roles of pathogens in the occurrence and development of animal diseases. ...

Tseng YC, et al. Egg-based influenza split virus vaccine with monoglycosylation induces cross-strain protection against influenza virus infections. Proc Natl Acad Sci U S A. 2019 Feb 19.  Abstract  
submitted by kickingbird at Feb, 21, 2019 from Proc Natl Acad Sci U S A. 2019 Feb 19 (via https://www.pnas.org/content/early/2019/02/12/1819197116)
Each year influenza virus infections cause hundreds of thousands of deaths worldwide and a significant level of morbidity with major economic burden. At the present time, vaccination with inactivated virus ...

Yokomichi H, et al. Incidence of hospitalisation for severe complications of influenza virus infection in Japanese patients between 2012 and 2016: a cross-sectional study using routinely collected administrative data. BMJ Open. 2019 Jan 17;9(1):e024687.  Abstract  
submitted by kickingbird at Feb, 21, 2019 from BMJ Open. 2019 Jan 17;9(1):e024687 (via https://bmjopen.bmj.com/content/9/1/e024687)
OBJECTIVE: To calculate the incidence of hospitalisation due to acute respiratory failure, pneumonia, acute respiratory distress syndrome (ARDS), febrile seizures and encephalitis/encephalopathy among ...

Gerlach T, Elbahesh H, Saletti G, Rimmelzwaan G. Recombinant influenza A viruses as vaccine vectors. Expert Rev Vaccines. 2019 Feb 19..  Abstract  
submitted by kickingbird at Feb, 21, 2019 from Expert Rev Vaccines. 2019 Feb 19. (via https://www.ncbi.nlm.nih.gov/pubmed/30777467)
Various viruses, including poxviruses, adenoviruses and vesicular stomatitis virus, have been considered as vaccine vectors for the delivery of antigens of interest in the development of vaccines against ...

Smieszek T, Lazzari G, Salathé M. Assessing the Dynamics and Control of Droplet- and Aerosol-Transmitted Influenza Using an Indoor Positioning System. Sci Rep. 2019 Feb 18;9(1):2185..  Abstract  
submitted by kickingbird at Feb, 21, 2019 from Sci Rep. 2019 Feb 18;9(1):2185. (via https://www.ncbi.nlm.nih.gov/pubmed/30778136)
There is increasing evidence that aerosol transmission is a major contributor to the spread of influenza. Despite this, virtually all studies assessing the dynamics and control of influenza assume that ...

Koutsakos M, et al. Human CD8+ T cell cross-reactivity across influenza A, B and C viruses. Nat Immunol. 2019 Feb 18..  Abstract  
submitted by kickingbird at Feb, 21, 2019 from Nat Immunol. 2019 Feb 18. (via https://www.nature.com/articles/s41590-019-0320-6)
Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally and infect humans, with IAV and IBV causing the most severe disease. CD8+ T cells confer cross-protection against IAV strains, ...

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