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2024-4-30 19:13:14
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Maslanka Figueroa S, et al. Influenza A virus mimetic nanoparticles trigger selective cell uptake. Proc Natl Acad Sci U S A. 2019 Apr 29..  Abstract  
submitted by kickingbird at May, 2, 2019 from Proc Natl Acad Sci U S A. 2019 Apr 29. (via https://www.pnas.org/content/early/2019/04/25/1902563116)
Poor target cell specificity is currently a major shortcoming of nanoparticles (NPs) used for biomedical applications. It causes significant material loss to off-target sites and poor availability at the ...

Soh YS, et al. Comprehensive mapping of adaptation of the avian influenza polymerase protein PB2 to humans. Elife. 2019 Apr 30;8.  Abstract  
submitted by kickingbird at May, 2, 2019 from Elife. 2019 Apr 30;8 (via https://elifesciences.org/articles/45079)
Viruses like influenza are infamous for their ability to adapt to new hosts. Retrospective studies of natural zoonoses and passaging in the lab have identified a modest number of host-adaptive mutations. ...

Hornick EE, et al. Dendritic cell NLRC4 regulates influenza A virus-specific CD4 T cell responses through FasL expression.. J Clin Invest. 2019 Apr 30;130.  Abstract  
submitted by kickingbird at May, 2, 2019 from J Clin Invest. 2019 Apr 30;130 (via https://www.jci.org/articles/view/124937)
Influenza A virus (IAV)-specific T cell responses are important correlates of protection during primary and subsequent infections. Generation and maintenance of robust IAV-specific T cell responses relies ...

Noor M, et al. Influenza Virus Subtyping by Multiplex PCR during Winter Months of 2017~2018. J Coll Physicians Surg Pak. 2019 May;29(5):459-462.  Abstract  
submitted by kickingbird at May, 2, 2019 from J Coll Physicians Surg Pak. 2019 May;29(5):459-462 (via https://www.jcpsp.pk/archive/2019/May2019/16.pdf)
OBJECTIVE: To determine the frequency of infections caused by Influenza viruses, i.e. Influenza A (H1N1) pdm09, Influenza A (H3N2) and Influenza B in patients presenting with respiratory tract infections, ...

Elbahesh H, Gerlach T, Saletti G, Rimmelzwaan G. Response Modifiers: Tweaking the Immune Response Against Influenza A Virus. Front Immunol. 2019 Apr 12;10:809.  Abstract  
submitted by kickingbird at May, 1, 2019 from Front Immunol. 2019 Apr 12;10:809 (via https://www.frontiersin.org/articles/10.3389/fimmu.2019.0080)
Despite causing pandemics and yearly epidemics that result in significant morbidity and mortality, our arsenal of options to treat influenza A virus (IAV) infections remains limited and is challenged by ...

Liu X, et al. Evidence for a novel mechanism of influenza A virus host adaption modulated by PB2-627. FEBS J. 2019 Apr 29..  Abstract  
submitted by kickingbird at May, 1, 2019 from FEBS J. 2019 Apr 29. (via https://febs.onlinelibrary.wiley.com/doi/abs/10.1111/febs.14)
Influenza virus cross-species transmission is restricted by the host, but viruses overcome this restriction by accumulating mutations which allow them to adapt to a new host. Among the many factors which ...

Shen X, Pu Z, Irwin DM, Shen Y. No gene communication between the human H3N2 and H1N1 pandemic 2009 influenza A viruses. J Infect. 2019 Apr 25.  Abstract  
submitted by kickingbird at Apr, 29, 2019 from J Infect. 2019 Apr 25 (via https://www.journalofinfection.com/article/S0163-4453(19)301)
Recently, a study in this journal suggested that the 2014 H1N1 pandemic 2009 (H1N1/pdm2009) had gene communication with 2016/2017 H3N2. The influenza A H1N1/pdm2009 virus, a novel swine-derived, triple ...

Xiang B, et al. Genetic characterization of H7N4 avian influenza virus in China in 2018. J Infect. 2019 Apr 25.  Abstract  
submitted by kickingbird at Apr, 29, 2019 from J Infect. 2019 Apr 25 (via https://www.journalofinfection.com/article/S0163-4453(19)301)
Recent study in this journal reported that the first case of human infection with H7N4 avian influenza virus (AIV) was confirmed in China.1 Subsequently, 11 H7N4 AIVs were isolated from poultries, 4 viruses ...

Cui B, Liu ZP, Ke J, Tian Y. Determinants of highly pathogenic avian influenza outbreak information sources, risk perception and adoption of biosecurity behaviors among poultry farmers in China. Prev Vet Med. 2019 Jun 1;167:25-31.  Abstract  
submitted by kickingbird at Apr, 29, 2019 from Prev Vet Med. 2019 Jun 1;167:25-31 (via https://www.sciencedirect.com/science/article/pii/S016758771)
The implementation of biosecurity measures among farmers is the first line of defense against highly pathogenic avian influenza (HPAI) on poultry farms. Yet much less is known about the association between ...

Li Y, et al. Prevalence, distribution and risk factors of farmer reported swine influenza infection in Guangdong Province, China. Prev Vet Med. 2019 Jun 1;167:1-8.  Abstract  
submitted by kickingbird at Apr, 29, 2019 from Prev Vet Med. 2019 Jun 1;167:1-8 (via https://www.sciencedirect.com/science/article/pii/S016758771)
A cross-sectional study was undertaken to better understand the husbandry, management and biosecurity practices of pig farms in Guangdong Province (GD), China to identify risk factors for farmer reported ...

Guo F, Shen X, Irwin DM, Shen Y. Avian influenza A viruses H5Nx (N1, N2, N6 and N8) show different adaptations of their codon usage patterns to their hosts. J Infect. 2019 Apr 25. pii: S0163-4453(19)30126-4.  Abstract  
submitted by kickingbird at Apr, 29, 2019 from J Infect. 2019 Apr 25. pii: S0163-4453(19)30126-4 (via https://www.journalofinfection.com/article/S0163-4453(19)301)
A recent study in this journal identified three H5 highly pathogenic avian influenza A viruses (HPAIVs) with differing NA subtypes (N1, N6 and N8) and revealed that while the three isolates were all highly ...

Poen MJ, et al. Co-circulation of genetically distinct highly pathogenic avian influenza A clade 2.3.4.4 (H5N6) viruses in wild waterfowl and poultry in Europe and East Asia, 2017~18. Virus Evol. 2019 Apr 22;5(1):vez004.  Abstract  
submitted by kickingbird at Apr, 28, 2019 from Virus Evol. 2019 Apr 22;5(1):vez004 (via https://academic.oup.com/ve/article/5/1/vez004/5476200)
Highly pathogenic avian influenza (HPAI) H5 clade 2.3.4.4 viruses were first introduced into Europe in late 2014 and re-introduced in late 2016, following detections in Asia and Russia. In contrast to ...

Holwerda M, et al. Determining the Replication Kinetics and Cellular Tropism of Influenza D Virus on Primary Well-Differentiated Human Airway Epithelial Cells. Viruses. 2019 Apr 24;11(4)..  Abstract  
submitted by kickingbird at Apr, 28, 2019 from Viruses. 2019 Apr 24;11(4). (via https://www.mdpi.com/1999-4915/11/4/377)
Influenza viruses are notorious pathogens that frequently cross the species barrier with often severe consequences for both animal and human health. In 2011, a novel member of the Orthomyxoviridae family, ...

Novianti AN, et al. Whole-Genome Sequence of an Avian Influenza A/H9N2 Virus Isolated from an Apparently Healthy Chicken at a Live-Poultry Market in Indonesia. Microbiol Resour Announc. 2019 Apr 25;8(17)..  Abstract  
submitted by kickingbird at Apr, 28, 2019 from Microbiol Resour Announc. 2019 Apr 25;8(17). (via https://mra.asm.org/content/8/17/e01671-18)
We isolated an avian influenza A/H9N2 virus from an apparently healthy chicken at a live-poultry market in January 2018. This is the first report of a whole-genome sequence of A/H9N2 virus in Indonesia. ...

Mi?o S, et al. Equine influenza virus in Asia: phylogeographic pattern and molecular features revealed the circulation of an autochthonous lineage. J Virol. 2019 Apr 24..  Abstract  
submitted by kickingbird at Apr, 27, 2019 from J Virol. 2019 Apr 24. (via https://jvi.asm.org/content/early/2019/04/18/JVI.00116-19)
Equine influenza virus (EIV) causes severe acute respiratory disease in horses. Currently, the strains belonging to the H3N8 genotype are divided into two clades, Florida clade 1 (FC1) and Florida clade ...

Toolsie O, Tehreem A, Diaz-Fuentes G. Influenza A Pneumonia Associated with Diffuse Alveolar Hemorrhage. A Case Report and Literature Review. Am J Case Rep. 2019 Apr 25;20:592-596.  Abstract  
submitted by kickingbird at Apr, 27, 2019 from Am J Case Rep. 2019 Apr 25;20:592-596 (via https://www.amjcaserep.com/abstract/index/idArt/913801)
BACKGROUND Diffuse alveolar hemorrhage (DAH) represents a life-threatening complication for many respiratory infections. We present a case of a patient with influenza A pneumonia associated with DAH. CASE ...

Tang BM, Feng CG, McLean AS. Understanding the role of host response in influenza pneumonitis. Intensive Care Med. 2019 Apr 24..  Abstract  
submitted by kickingbird at Apr, 27, 2019 from Intensive Care Med. 2019 Apr 24. (via https://link.springer.com/article/10.1007%2Fs00134-019-05582)
Most influenza-related deaths are caused by influenza pneumonitis, a serious complication of influenza virus infection characterised by uncontrolled lung inflammation, acute lung injury and respiratory ...

Loubet P, Nguyen C, Burnet E, Launay O. Influenza vaccination of pregnant women in Paris, France: Knowledge, attitudes and practices among midwives. PLoS One. 2019 Apr 25;14(4):e0215251.  Abstract  
submitted by kickingbird at Apr, 27, 2019 from PLoS One. 2019 Apr 25;14(4):e0215251 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
INTRODUCTION: In France, midwives have been authorized to prescribe vaccines since 2016. Yet vaccination coverage among pregnant women remains low. Understanding the knowledge, attitudes and practices ...

Zhao ZX, Cheng LP, Li M, Pang W, Wu FH. Discovery of novel acylhydrazone neuraminidase inhibitors. Eur J Med Chem. 2019 Apr 5;173:305-313.  Abstract  
submitted by kickingbird at Apr, 27, 2019 from Eur J Med Chem. 2019 Apr 5;173:305-313 (via https://www.sciencedirect.com/science/article/pii/S022352341)
Neuraminidase (NA) plays a crucial role in the replication and transmission of influenza virus. NA inhibitors have been developed as effective treatments for influenza A and B infections. In this paper, ...

Kukushkin VI, et al. Highly sensitive detection of influenza virus with SERS aptasensor. PLoS One. 2019 Apr 25;14(4):e0216247.  Abstract  
submitted by kickingbird at Apr, 27, 2019 from PLoS One. 2019 Apr 25;14(4):e0216247 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
Highly sensitive and rapid technology of surface enhanced Raman scattering (SERS) was applied to create aptasensors for influenza virus detection. SERS achieves 106?109 times signal amplification, yielding ...

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