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Collins JP, et al. Outcomes of immunocompromised adults hospitalized with laboratory-confirmed influenza in the United States, 2011~2015. Clin Infect Dis. 2019 Jul 11..  Abstract  
submitted by kickingbird at Jul, 15, 2019 from Clin Infect Dis. 2019 Jul 11. (via https://academic.oup.com/cid/advance-article-abstract/doi/10)
BACKGROUND: Hospitalized immunocompromised (IC) adults with influenza may have worse outcomes than hospitalized non-immunocompromised adults.METHODS: We identified adults (≥18 years) hospitalized with ...

Abood RN, et al. IL-22-binding protein exacerbates influenza, bacterial super-infection. Mucosal Immunol. 2019 Jul 11..  Abstract  
submitted by kickingbird at Jul, 15, 2019 from Mucosal Immunol. 2019 Jul 11. (via https://www.nature.com/articles/s41385-019-0188-7)
Secondary bacterial pneumonia is a significant complication of severe influenza infection and Staphylococcus aureus and Streptococcus pneumoniae are the primary pathogens of interest. IL-22 promotes S. ...

Lee DH, et al. Genome Sequences of an H9N2 Avian Influenza Virus Strain Found in Pakistan in 2017. Microbiol Resour Announc. 2019 Jul 11;8(28)..  Abstract  
submitted by kickingbird at Jul, 15, 2019 from Microbiol Resour Announc. 2019 Jul 11;8(28). (via https://mra.asm.org/content/8/28/e00433-19)
In 2017, we isolated an H9N2 avian influenza virus in Pakistan. Genetic analysis showed that the A/chicken/Kasoor/SI36/2017(H9N2) isolate belongs to the G1 lineage. In addition, this isolate possesses ...

Carlock MA, et al. Impact of age and pre-existing influenza on the induction of human antibody responses against influenza B viruses. Hum Vaccin Immunother. 2019 Jul 10..  Abstract  
submitted by kickingbird at Jul, 12, 2019 from Hum Vaccin Immunother. 2019 Jul 10. (via https://www.tandfonline.com/doi/abs/10.1080/21645515.2019.16)
Pre-existing immunity to influenza is dependent on a number of factors and can vary greatly within and across influenza subtypes. In this study, volunteers (aged 18-85 years) were vaccinated with split, ...

Chua H, et al. Effectiveness of partial and full influenza vaccination in children aged <9 years in Hong Kong, 2011~2019. J Infect Dis. 2019 Jul 9..  Abstract  
submitted by kickingbird at Jul, 12, 2019 from J Infect Dis. 2019 Jul 9. (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
INTRODUCTION: Two doses of influenza vaccination are recommended for previously unvaccinated children aged METHODS: Using the test-negative design we enrolled 23,187 children aged RESULTS: Overall VE estimates ...

Trebbien R, et al. A case of reassortant seasonal influenza A(H1N2) virus, Denmark, April 2019. Euro Surveill. 2019 Jul;24(27)..  Abstract  
submitted by kickingbird at Jul, 12, 2019 from Euro Surveill. 2019 Jul;24(27). (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
A reassortant influenza A subtype H1N2 virus with gene segments from seasonal A(H1N1)pdm09 virus (HA, MP, NP, NS, PA, PB1 and PB2) and seasonal A(H3N2) virus (NA) was identified in a routine surveillance ...

Mishin VP, Patel MC, Chesnokov A, De La Cruz J, Ng. Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir. Emerg Infect Dis. 2019 Oct.  Abstract  
submitted by kickingbird at Jul, 12, 2019 from Emerg Infect Dis. 2019 Oct (via https://wwwnc.cdc.gov/eid/article/25/10/19-0607_article)
Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2-98.3 nmol/L); susceptibility pattern was influenza A ? B ? C ? D. ...

Wang G, et al. Characterization of swine-origin H1N1 canine influenza viruses. Emerg Microbes Infect. 2019;8(1):1017-1026.  Abstract  
submitted by kickingbird at Jul, 12, 2019 from Emerg Microbes Infect. 2019;8(1):1017-1026 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
Host switch events of influenza A viruses (IAVs) continuously pose a zoonotic threat to humans. In 2013, swine-origin H1N1 IAVs emerged in dogs soon after they were detected in swine in the Guangxi province ...

Kode SS, et al. A novel I117T substitution in neuraminidase of highly pathogenic avian influenza H5N1 virus conferring reduced susceptibility to oseltamivir and zanamivir. Vet Microbiol. 2019 Jun 5;235:21-24..  Abstract  
submitted by kickingbird at Jul, 12, 2019 from Vet Microbiol. 2019 Jun 5;235:21-24. (via https://www.sciencedirect.com/science/article/pii/S037811351)
Occurrence of avian influenza (AI) with Neuraminidase (NA) mutations which confer reduced neuraminidase inhibitor (NAI) susceptibility has remained a cause of concern. The susceptibility to NAIs of 67 ...

Peacock TP, Sheppard CM, Staller E, Barclay WS. Host Determinants of Influenza RNA Synthesis. Annu Rev Virol. 2019 Jul 5.  Abstract  
submitted by kickingbird at Jul, 12, 2019 from Annu Rev Virol. 2019 Jul 5 (via https://www.annualreviews.org/doi/10.1146/annurev-virology-0)
Influenza viruses are a leading cause of seasonal and pandemic respiratory illness. Influenza is a negative-sense single-stranded RNA virus that encodes its own RNA-dependent RNA polymerase (RdRp) for ...

Huo C, et al. Genomic and Bioinformatic Characterization of Mouse Mast Cells (P815) Upon Different Influenza A Virus (H1N1, H5N1, and H7N2) Infections. Front Genet. 2019 Jun 21;10:595.  Abstract  
submitted by kickingbird at Jul, 12, 2019 from Front Genet. 2019 Jun 21;10:595 (via https://www.frontiersin.org/articles/10.3389/fgene.2019.0059)
Influenza A virus (IAV) is a segmented negative-stranded RNA virus that brings a potentially serious threat to public health and animal husbandry. Mast cells play an important role in both the inherent ...

Elhakim M, et al. Epidemiology of severe cases of influenza and other acute respiratory infections in the Eastern Mediterranean Region, July 2016 to June 2018. J Infect Public Health. 2019 Jul 4.  Abstract  
submitted by kickingbird at Jul, 12, 2019 from J Infect Public Health. 2019 Jul 4 (via https://www.ncbi.nlm.nih.gov/pubmed/31281105)
BACKGROUND: Influenza surveillance systems in the Eastern Mediterranean Region have been strengthened in the past few years and 16 of the 19 countries in the Region with functional influenza surveillance ...

Mei K, et al. Different Pathogenicity and Transmissibility of Goose-Origin H5N6 Avian Influenza Viruses in Chickens. Viruses. 2019 Jul 4;11(7)..  Abstract  
submitted by kickingbird at Jul, 10, 2019 from Viruses. 2019 Jul 4;11(7). (via https://www.mdpi.com/1999-4915/11/7/612)
Highly pathogenic avian influenza H5N6 viruses have been circulating in poultry in Asia since 2013 and producing serious diseases in chickens. Here, we analyzed the genetic properties of 10 H5N6 subtypes ...

Ding P, et al. A Universal Influenza Nanovaccine for "Mixing Vessel" Hosts Confers Potential Ability to Block Cross-Species Transmission. Adv Healthc Mater. 2019 Jul 3:e1900456..  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Adv Healthc Mater. 2019 Jul 3:e1900456. (via https://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.2019004)
Influenza A virus (IAV), a deadly zoonotic pathogen, poses a tremendous threat and burden to global health systems. Pigs act as "mixing vessel" hosts to support and generate new pandemic viruses. Preventing ...

Basch CH, Fera J, Garcia P. Readability of influenza information online: Implications for consumer health. Am J Infect Control. 2019 Jun 25.  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Am J Infect Control. 2019 Jun 25 (via https://www.ajicjournal.org/article/S0196-6553(19)30461-4/fu)
BACKGROUND: Influenza (flu) is pervasive and burdensome. The purpose of this study was to determine the readability levels of online articles related to flu.METHODS: Using the search term "influenza," ...

To J, Torres J. Viroporins in the Influenza Virus. Cells. 2019 Jun 29;8(7)..  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Cells. 2019 Jun 29;8(7). (via https://www.mdpi.com/2073-4409/8/7/654)
Influenza is a highly contagious virus that causes seasonal epidemics and unpredictable pandemics. Four influenza virus types have been identified to date: A, B, C, and D, where only A-C are known to infect ...

Zhang K, et al. Structural basis for influenza virus NS1 protein block of mRNA nuclear export. Nat Microbiol. 2019 Jul 1..  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Nat Microbiol. 2019 Jul 1. (via https://www.nature.com/articles/s41564-019-0482-x)
Influenza viruses antagonize key immune defence mechanisms via the virulence factor non-structural protein 1 (NS1). A key mechanism of virulence by NS1 is blocking nuclear export of host messenger RNAs, ...

Wang GL, Gray GC, Chen JM, Ma MJ. Will China´s H7N9 Control Strategy Continue to Be Effective?. Open Forum Infect Dis. 2019 May 31;6(6):ofz258.  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Open Forum Infect Dis. 2019 May 31;6(6):ofz258 (via https://academic.oup.com/ofid/article/6/6/ofz258/5509882)
Since the first outbreak of avian influenza A(H7N9) virus in China in early 2013, several interventions to control the transmission of H7N9 virus from poultry to humans have been implemented. Temporarily ...

Watkins LC, Liang R, Swanson JMJ, DeGrado WF, Voth. Proton Induced Conformational and Hydration Dynamics in the Influenza A M2 Channel. J Am Chem Soc. 2019 Jul 2..  Abstract  
submitted by kickingbird at Jul, 7, 2019 from J Am Chem Soc. 2019 Jul 2. (via https://pubs.acs.org/doi/10.1021/jacs.9b05136)
The influenza A M2 protein is an acid-activated proton channel responsible for the acidification of the inside of the virus, a critical step in the viral life cycle. This channel has four central histidine ...

Zhou L, Li Q, Uyeki TM.. Estimated Incubation Period and Serial Interval for Human-to-Human Influenza A(H7N9) Virus Transmission. Emerg Infect Dis. 2019 Oct 17;25(10)..  Abstract  
submitted by kickingbird at Jul, 7, 2019 from Emerg Infect Dis. 2019 Oct 17;25(10). (via https://wwwnc.cdc.gov/eid/article/25/10/19-0117_article)
We estimated the incubation period and serial interval for human-to-human-transmitted avian influenza A(H7N9) virus infection using case-patient clusters from epidemics in China during 2013-2017. The median ...

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