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Chen KY, et al. Influenza virus polymerase subunits co-evolve to ensure proper levels of dimerization of the heterotrimer. PLoS Pathog. 2019 Oct 3;15(10).  Abstract  
submitted by kickingbird at Oct, 5, 2019 from PLoS Pathog. 2019 Oct 3;15(10) (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
The influenza A virus RNA-dependent RNA polymerase complex consists in three subunits, PB2, PB1 and PA, that perform transcription and replication of the viral genome through very distinct mechanisms. ...

Sun J, et al. Novel H5N6 Avian Influenza Virus Reassortants with European H5N8 Isolated in Migratory Birds, China. Transbound Emerg Dis. 2019 Oct 3.  Abstract  
submitted by kickingbird at Oct, 5, 2019 from Transbound Emerg Dis. 2019 Oct 3 (via https://onlinelibrary.wiley.com/doi/abs/10.1111/tbed.13380)
Five novel H5N6 influenza viruses, including four highly pathogenic avian influenza viruses and one low pathogenic avian influenza virus, were isolated from migratory birds in Ningxia, China in November ...

Gao J, Pasion J, Sanchez-Petitto G, Law J. Influenza virus B-associated hemophagocytic lymphohistiocytosis. Hematol Rep. 2019 Sep 18;11(3):8268..  Abstract  
submitted by kickingbird at Oct, 5, 2019 from Hematol Rep. 2019 Sep 18;11(3):8268. (via https://www.pagepress.org/journals/index.php/hr/article/view)
This original report describes the diagnosis and management of a male with hemophagocytic lymphohistiocytosis (HLH) triggered by influenza B virus infection. The patient was diagnosed with HLH- 2004 clinical ...

Popova AV, et al. Allele-specific nonstationarity in evolution of influenza A virus surface proteins. Proc Natl Acad Sci U S A. 2019 Oct 2..  Abstract  
submitted by kickingbird at Oct, 5, 2019 from Proc Natl Acad Sci U S A. 2019 Oct 2. (via https://www.pnas.org/content/early/2019/10/01/1904246116)
Influenza A virus (IAV) is a major public health problem and a pandemic threat. Its evolution is largely driven by diversifying positive selection so that relative fitness of different amino acid variants ...

Nogales A, L DeDiego M. Host Single Nucleotide Polymorphisms Modulating Influenza A Virus Disease in Humans. Pathogens. 2019 Sep 30;8(4)..  Abstract  
submitted by kickingbird at Oct, 3, 2019 from Pathogens. 2019 Sep 30;8(4). (via https://www.mdpi.com/2076-0817/8/4/168)
A large number of human genes associated with viral infections contain single nucleotide polymorphisms (SNPs), which represent a genetic variation caused by the change of a single nucleotide in the DNA ...

Furusawa Y, et al. Influenza Virus Polymerase Mutation Stabilizes a Foreign Gene Inserted into the Virus Genome by Enhancing the Transcription/Replication Efficiency of the Modified Segment. MBio. 2019 Oct 1;10(5)..  Abstract  
submitted by kickingbird at Oct, 3, 2019 from MBio. 2019 Oct 1;10(5). (via https://mbio.asm.org/content/10/5/e01794-19)
We previously attempted to establish a reporter influenza virus by inserting the gene for the Venus fluorescent protein into the NS segment of influenza A/Puerto Rico/8/34 (PR8, H1N1) virus to yield WT-Venus-PR8. ...

Nantima N, et al. Managing the challenges of a highly pathogenic avian influenza H5N8 outbreak in Uganda: a case study. Rev Sci Tech. 2019 May;38(1):225-237..  Abstract  
submitted by kickingbird at Oct, 1, 2019 from Rev Sci Tech. 2019 May;38(1):225-237. (via https://doc.oie.int/dyn/portal/index.seam?page=alo&aloId=388)
In 2016-2017, the H5N8 strain of highly pathogenic avian influenza (HPAI) spread worldwide and Uganda reported the first occurrence of the disease in its poultry and wild birds. Genetic analysis revealed ...

Kim GS, et al. The difference of detection rate of avian influenza virus in the wild bird surveillance using various methods. J Vet Sci. 2019 Sep;20(5):e56.  Abstract  
submitted by kickingbird at Oct, 1, 2019 from J Vet Sci. 2019 Sep;20(5):e56 (via http://mr.crossref.org/iPage?doi=10.4142%2Fjvs.2019.20.e56)
Korea is located within the East Asian-Australian flyway of wild migratory birds during the fall and winter seasons. Consequently, the likelihood of introduction of numerous subtypes and pathotypes of ...

Tsai CH, et al. Generation of Stable Influenza Virus Hemagglutinin through Structure-Guided Recombination. ACS Synth Biol. 2019 Sep 30..  Abstract  
submitted by kickingbird at Oct, 1, 2019 from ACS Synth Biol. 2019 Sep 30. (via https://www.ncbi.nlm.nih.gov/pubmed/31565926)
Hemagglutinin (HA) is the major surface antigen of influenza virus and the most promising influenza vaccine immunogen. In 2013, the devastating H7N9 influenza virus was identified in China, which induced ...

Walaza S, et al. Influenza and tuberculosis co-infection: A systematic review. Influenza Other Respir Viruses. 2019 Sep 30..  Abstract  
submitted by kickingbird at Oct, 1, 2019 from Influenza Other Respir Viruses. 2019 Sep 30. (via https://onlinelibrary.wiley.com/doi/full/10.1111/irv.12670)
INTRODUCTION: There are limited data on risk of severe disease or outcomes in patients with influenza and pulmonary tuberculosis (PTB) co-infection compared to those with single infection.METHODS: We conducted ...

Tsang TK, et al. Association between the respiratory microbiome and susceptibility to influenza virus infection. Clin Infect Dis. 2019 Sep 28.  Abstract  
submitted by kickingbird at Sep, 30, 2019 from Clin Infect Dis. 2019 Sep 28 (via https://www.ncbi.nlm.nih.gov/pubmed/31562814)
BACKGROUND: Previous studies suggest that the nose/throat microbiome may play an important role in shaping host immunity and modifying the risk of respiratory infection. Our aim is to quantify the association ...

Wong HH, Fung K, Nicholls JM. MDCK-B4GalNT2 cells disclose a α2,3-sialic acid requirement for the 2009 pandemic H1N1 A/California/04/2009 and NA aid entry of A/WSN/33. Emerg Microbes Infect. 2019;8(1):1428-1437.  Abstract  
submitted by kickingbird at Sep, 30, 2019 from Emerg Microbes Infect. 2019;8(1):1428-1437 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2019.1)
Switching of receptor binding preference has been widely considered as one of the necessary mutations for avian influenza viruses, enabling efficient transmissions between human hosts. By stably overexpressing ...

Le KP, et al. Molecular Docking of Broad-Spectrum Antibodies on Hemagglutinins of Influenza A Virus. Evol Bioinform Online. 2019 Sep 16;15:117693431987.  Abstract  
submitted by kickingbird at Sep, 29, 2019 from Evol Bioinform Online. 2019 Sep 16;15:117693431987 (via https://journals.sagepub.com/doi/10.1177/1176934319876938)
AbstractInfluenza A has caused several deadly pandemics throughout human history. The virus is often resistant to developed treatments because of its genetic drift or shift property. Broad-spectrum antibodies ...

Motta FC, Born PS, Resende PC, Brown D, et al. A cheap and accurate RT-PCR-melting temperature assay for real time Influenza B lineages discrimination. J Clin Microbiol. 2019 Sep 25..  Abstract  
submitted by kickingbird at Sep, 29, 2019 from J Clin Microbiol. 2019 Sep 25. (via https://jcm.asm.org/content/early/2019/09/19/JCM.00602-19)
In this work, we describe a SYBR-Green one-step RT-PCR protocol coupled with a melting temperature analysis (RT-PCR-Tm), which allows the discrimination of influenza B lineages Yamagata and Victoria. The ...

Feng H, et al. Food Additives as Novel Influenza Vaccine Adjuvants. Vaccines (Basel). 2019 Sep 24;7(4)..  Abstract  
submitted by kickingbird at Sep, 29, 2019 from Vaccines (Basel). 2019 Sep 24;7(4). (via https://www.mdpi.com/2076-393X/7/4/127)
Influenza is a major threat to public health. Vaccination is an effective strategy to control influenza; however, the current inactivated influenza vaccine has mild immunogenicity and exhibits suboptimal ...

Kim MJ, Oh MJ. Eosinophilic Enteritis Presenting as Massive Ascites after Influenza A Virus Infection in a Young Female. Korean J Gastroenterol. 2019 Sep 25;74(3):163-167..  Abstract  
submitted by kickingbird at Sep, 29, 2019 from Korean J Gastroenterol. 2019 Sep 25;74(3):163-167. (via https://www.ncbi.nlm.nih.gov/pubmed/31554032)
Eosinophilic gastrointestinal disorder (EGID) is an uncommon disease that is accompanied by intestinal eosinophil infiltration without a secondary cause of eosinophilia. Eosinophilic enteritis is a secondary ...

Roosenhoff R, et al. Viral Kinetics and Resistance Development in Children Treated with Neuraminidase Inhibitors: The Influenza Resistance Information Study (IRIS). Clin Infect Dis. 2019 Sep 27.  Abstract  
submitted by kickingbird at Sep, 29, 2019 from Clin Infect Dis. 2019 Sep 27 (via https://academic.oup.com/cid/advance-article/doi/10.1093/cid)
BACKGROUND: The effect of age, baseline viral load, vaccination status, antiviral therapy and emergence of drug resistance on viral shedding in children infected with influenza A or B virus was studied.METHODS: ...

Wright A, Patel R, Motamedi D. Influenza Vaccine-related Subacromial/Subdeltoid Bursitis: A Case Report. J Radiol Case Rep. 2019 Jun 30;13(6):24-31..  Abstract  
submitted by kickingbird at Sep, 29, 2019 from J Radiol Case Rep. 2019 Jun 30;13(6):24-31. (via http://www.radiologycases.com/index.php/radiologycases/artic)
Serious side effects of vaccinations are not common, though rare complications can occur. We present a case of one such uncommon side effect, influenza vaccine-related subacromial/subdeltoid bursitis. ...

Poen MJ, et al. Evidence of the Presence of Low Pathogenic Avian Influenza A Viruses in Wild Waterfowl in 2018 in South Africa. Pathogens. 2019 Sep 25;8(4)..  Abstract  
submitted by kickingbird at Sep, 29, 2019 from Pathogens. 2019 Sep 25;8(4). (via https://www.mdpi.com/2076-0817/8/4/163)
Avian influenza viruses are pathogens of global concern to both animal and human health. Wild birds are the natural reservoir of avian influenza viruses and facilitate virus transport over large distances. ...

Chen LL, et al. Assessment of population susceptibility to upcoming seasonal influenza epidemic strain using interepidemic emerging influenza virus strains. Epidemiol Infect. 2019 Sep 26;147:e279..  Abstract  
submitted by kickingbird at Sep, 29, 2019 from Epidemiol Infect. 2019 Sep 26;147:e279. (via https://www.cambridge.org/core/journals/epidemiology-and-inf)
Seasonal influenza virus epidemics have a major impact on healthcare systems. Data on population susceptibility to emerging influenza virus strains during the interepidemic period can guide planning for ...

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