Taniguchi K, Noshi T, Omoto S, Sato A, Shishido T,. The impact of PA/I38 substitutions and PA polymorphisms on the susceptibility of zoonotic influenza A viruses to baloxavir. Arch Virol. 2024 Jan 12;169(2):29. Abstract
submitted by kickingbird at Jan, 18, 2024 from Arch Virol. 2024 Jan 12;169(2):29 (via https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10786730/)
Genetic reassortment of avian, swine, and human influenza A viruses (IAVs) poses potential pandemic risks. Surveillance is important for influenza pandemic preparedness, but the susceptibility of zoonotic ... Uno N, Ross TM. Multivalent next generation influenza virus vaccines protect against seasonal and pre-pandemic viruses. Sci Rep. 2024 Jan 16;14(1):1440. Abstract
submitted by kickingbird at Jan, 18, 2024 from Sci Rep. 2024 Jan 16;14(1):1440 (via https://www.nature.com/articles/s41598-023-51024-0)
Each year, new influenza virus vaccine formulations are generated to keep up with continuously circulating and mutating viral variants. A next-generation influenza virus vaccine would provide long-lasting, ... Kwasnik M, Rola J, Rozek W. Influenza D in Domestic and Wild Animals. Viruses. 2023 Dec 15;15(12):2433. Abstract
submitted by kickingbird at Jan, 17, 2024 from Viruses. 2023 Dec 15;15(12):2433 (via https://www.mdpi.com/1999-4915/15/12/2433)
Influenza D virus (IDV) infections have been observed in animals worldwide, confirmed through both serological and molecular tests, as well as virus isolation. IDV possesses unique properties that distinguish ... Chen B, Guo G, Wang G, Zhu Q, Wang L, Shi W, Wang. ATG7/GAPLINC/IRF3 axis plays a critical role in regulating pathogenesis of influenza A virus. PLoS Pathog. 2024 Jan 16;20(1):e1011958. Abstract
submitted by kickingbird at Jan, 17, 2024 from PLoS Pathog. 2024 Jan 16;20(1):e1011958 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Autophagy-related protein 7 (ATG7) is an essential autophagy effector enzyme. Although it is well known that autophagy plays crucial roles in the infections with various viruses including influenza A virus ... Yang H, Lei G, Deng Z, Sun F, Tian Y, Cheng J, Yu. An Engineered Influenza a Virus Expressing the Co-Stimulator OX40L as an Oncolytic Agent Against Hepatocellular Carcinoma. J Hepatocell Carcinoma. 2024 Jan 9;11:1-13. Abstract
submitted by kickingbird at Jan, 16, 2024 from J Hepatocell Carcinoma. 2024 Jan 9;11:1-13 (via https://www.dovepress.com/getfile.php?fileID=95852)
Background: Oncolytic virus (OV) therapy has emerged as a promising novel form of immunotherapy. Moreover, an increasing number of studies have shown that the therapeutic efficacy of OV can be further ... Qiao M, Zhu F, Chen J, Li Y, Wang X. Effects of scheduled school breaks on the circulation of influenza in children, school-aged population and adults in China: a spatio-temporal analysis. Int J Infect Dis. 2024 Jan 11:S1201-9712(24)00005-. Abstract
submitted by kickingbird at Jan, 15, 2024 from Int J Infect Dis. 2024 Jan 11:S1201-9712(24)00005- (via https://www.ijidonline.com/article/S1201-9712(24)00005-5/ful)
Objectives: To investigate the effect of scheduled school break on circulation of influenza in young children, school-aged population and adults.Methods: In a spatial-temporal analysis using influenza ... Yamaguchi E, Hayama Y, Murato Y, Sawai K, Kondo S,. A case-control study of the infection risk of H5N8 highly pathogenic avian influenza in Japan during the winter of 2020-2021. Res Vet Sci. 2024 Jan 9;168:105149. Abstract
submitted by kickingbird at Jan, 15, 2024 from Res Vet Sci. 2024 Jan 9;168:105149 (via https://www.sciencedirect.com/science/article/abs/pii/S00345)
In Japan, outbreaks of H5N8 highly pathogenic avian influenza (HPAI) were reported between November 2020 and March 2021 in 52 poultry farms. Understanding HPAI epidemiology would help poultry industries ... Hulme KD, Tong ZWM, Rowntree LC, van de Sandt CE,. Increasing HbA1c is associated with reduced CD8+ T cell functionality in response to influenza virus in a TCR-dependent manner in individuals with diabetes mellitus. Cell Mol Life Sci. 2024 Jan 12;81(1):35. Abstract
submitted by kickingbird at Jan, 15, 2024 from Cell Mol Life Sci. 2024 Jan 12;81(1):35 (via https://link.springer.com/article/10.1007/s00018-023-05010-4)
Diabetes mellitus is on the rise globally and is a known susceptibility factor for severe influenza virus infections. However, the mechanisms by which diabetes increases the severity of an influenza virus ... Seo YR, Cho AY, Si YJ, Lee SI, Kim DJ, Jeong H, Kw. Evolution and Spread of Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus in Wild Birds, South Korea, 2022-2023. Emerg Infect Dis. 2024 Jan 12;30(2). Abstract
submitted by kickingbird at Jan, 14, 2024 from Emerg Infect Dis. 2024 Jan 12;30(2) (via https://pubmed.ncbi.nlm.nih.gov/38215495/)
During October 2022-March 2023, highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b virus caused outbreaks in South Korea, including 174 cases in wild birds. To understand the origin and role ... Ortigoza MB, Mobini CL, Rocha HL, Bartlett S, Loom. Inhibiting influenza virus transmission using a broadly acting neuraminidase that targets host sialic acids in the upper respiratory tract. mBio. 2024 Jan 11:e0220323. Abstract
submitted by kickingbird at Jan, 12, 2024 from mBio. 2024 Jan 11:e0220323 (via https://journals.asm.org/doi/10.1128/mbio.02203-23)
Influenza virus transmission studies have historically focused on viral mutations that alter hemagglutinin binding to sialic acid (SA) receptors in vitro. However, SA binding preference does not fully ... Lyashko AV, Timofeeva TA, Rudneva IA, Lomakina NF,. Antigenic Architecture of the H7N2 Influenza Virus Hemagglutinin Belonging to the North American Lineage. Int J Mol Sci. 2023 Dec 22;25(1):212. Abstract
submitted by kickingbird at Jan, 12, 2024 from Int J Mol Sci. 2023 Dec 22;25(1):212 (via https://www.mdpi.com/1422-0067/25/1/212)
The North American low pathogenic H7N2 avian influenza A viruses, which lack the 220-loop in the hemagglutinin (HA), possess dual receptor specificity for avian- and human-like receptors. The purpose of ... Si X, Wang L, Mengersen K, Hu W. Epidemiological features of seasonal influenza transmission among 11 climate zones in Chinese Mainland. Infect Dis Poverty. 2024 Jan 10;13(1):4. Abstract
submitted by kickingbird at Jan, 12, 2024 from Infect Dis Poverty. 2024 Jan 10;13(1):4 (via https://idpjournal.biomedcentral.com/articles/10.1186/s40249)
Background: Previous studies provided some evidence of meteorological factors influence seasonal influenza transmission patterns varying across regions and latitudes. However, research on seasonal influenza ... Maya-Badillo BA, Orta-Pineda G, Zavala-Vasco D, Ri. Influenza A virus antibodies in dogs, hunting dogs, and backyard pigs in Campeche, Mexico. Zoonoses Public Health. 2024 Jan 9. Abstract
submitted by kickingbird at Jan, 11, 2024 from Zoonoses Public Health. 2024 Jan 9 (via https://onlinelibrary.wiley.com/doi/10.1111/zph.13110)
Aims: This study aimed to identify exposure to human, swine, and avian influenza A virus subtypes in rural companion and hunting dogs, backyard pigs, and feral pigs.Methods and results: The study took ... Kayano T, Kobayashi T, Fujiwara S, Okada Y, Nishiu. Survey of exposure to stranded dolphins in Japan to investigate an outbreak of suspected infection with highly pathogenic avian influenza (H5N1) clade 2.3.4.4(b) in humans. New Microbes New Infect. 2023 Dec 16;56:101214. Abstract
submitted by kickingbird at Jan, 10, 2024 from New Microbes New Infect. 2023 Dec 16;56:101214 (via https://www.sciencedirect.com/science/article/pii/S205229752)
Background: A highly pathogenic avian influenza (HPAI) A (H5N1) virus has been detected in domestic and wild animals worldwide. The incidence of HPAI infections in sea mammals has been increasing, as is ... Jang SG, Kim YI, Casel MAB, Choi JH, Gil JR, Rollo. HA N193D substitution in the HPAI H5N1 virus alters receptor binding affinity and enhances virulence in mammalian hosts. Emerg Microbes Infect. 2024 Jan 8:2302854. Abstract
submitted by kickingbird at Jan, 9, 2024 from Emerg Microbes Infect. 2024 Jan 8:2302854 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
During the 2021/2022 winter season, we isolated highly pathogenic avian influenza (HPAI) H5N1 viruses harboring an amino acid substitution from Asparagine(N) to Aspartic acid (D) at residue 193 of the ... Howard LM, Jensen TL, Goll JB, Gelber CE, Bradley. Metabolomic Signatures Differentiate Immune Responses in Avian Influenza Vaccine Recipients. J Infect Dis. 2024 Jan 5:jiad611. Abstract
submitted by kickingbird at Jan, 6, 2024 from J Infect Dis. 2024 Jan 5:jiad611 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: Avian influenza viruses pose significant risk to human health. Vaccines targeting the hemagglutinin of these viruses are poorly immunogenic without the use of adjuvants.Methods: Twenty healthy ... Jin, K., Dai, Z., Shi, P. et al.. Severe pneumonia with co-infection of H5N1 and SARS-CoV-2: a case report. BMC Infect Dis 24, 31 (2024). Abstract
submitted by kickingbird at Jan, 6, 2024 from BMC Infect Dis 24, 31 (2024) (via https://bmcinfectdis.biomedcentral.com/articles/10.1186/s128)
BackgroundThe H5N1 influenza virus is a cause of severe pneumonia. Co-infection of influenza virus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may lead to poor prognosis of patients ... Wang Q, Liu Z, Zeng X, Zheng Y, Lan L, Wang X, Lai. Integrated analysis of miRNA-mRNA expression of newly emerging swine H3N2 influenza virus cross-species infection with tree shrews. Virol J. 2024 Jan 4;21(1):4. Abstract
submitted by kickingbird at Jan, 5, 2024 from Virol J. 2024 Jan 4;21(1):4 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: Cross-species transmission of zoonotic IAVs to humans is potentially widespread and lethal, posing a great threat to human health, and their cross-species transmission mechanism has attracted ... Elli S, Raffaini G, Guerrini M, Kosakovsky Pond S,. Molecular modeling and phylogenetic analyses highlight the role of amino acid 347 of the N1 subtype neuraminidase in influenza virus host range and interspecies adaptation. Front Microbiol. 2023 Dec 19;14:1309156. Abstract
submitted by kickingbird at Jan, 5, 2024 from Front Microbiol. 2023 Dec 19;14:1309156 (via https://www.frontiersin.org/articles/10.3389/fmicb.2023.1309)
The N1 neuraminidases (NAs) of avian and pandemic human influenza viruses contain tyrosine and asparagine, respectively, at position 347 on the rim of the catalytic site; the biological significance of ... Nu?ez IA, Jang H, Huang Y, Kelvin A, Ross TM. Influenza virus immune imprinting dictates the clinical outcomes in ferrets challenged with highly pathogenic avian influenza virus H5N1. Front Vet Sci. 2023 Dec 19;10:1286758. Abstract
submitted by kickingbird at Jan, 5, 2024 from Front Vet Sci. 2023 Dec 19;10:1286758 (via https://www.frontiersin.org/articles/10.3389/fvets.2023.1286)
Zoonotic transmission of H5N1 highly pathogenic avian influenza virus (HPAIV) into the human population is an increasing global threat. The recent 2022 HPAIV outbreak significantly highlighted this possibility, ... 7508 items, 20/Page, Page[12/376][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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