Huibin Lv, etc.,al. Evolution of antibody cross-reactivity to influenza H5N1 neuraminidase from an N2-specific germline. Cell Host & Microbe. Abstract
submitted by kickingbird at Oct, 18, 2025 from Cell Host & Microbe (via https://www.sciencedirect.com/science/article/abs/pii/S19313)
The ongoing spread of highly pathogenic avian influenza H5N1 clade 2.3.4.4b virus in animals and its occasional spillover to humans have raised concerns about a potential H5N1 pandemic. Although recent ... Gregory L Damhorst, Wilbur A Lam. Point-of-care and Home Use Influenza Diagnostics for Advancing Therapeutic and Public Health Strategies. The Journal of Infectious Diseases, Volume 232. Abstract
submitted by kickingbird at Oct, 18, 2025 from The Journal of Infectious Diseases, Volume 232 (via https://academic.oup.com/jid/article/232/Supplement_3/S314/8)
Point-of-care (POC) antigen-based diagnostics for influenza that have been granted waived status since the Clinical Laboratory Improvement Amendments of 1988 (CLIA-waived) have been available commercially ... Madeleine R Heldman, Michael J Boeckh, Michael G I. Influenza Antivirals for Prevention and Treatment in Immunocompromised People. The Journal of Infectious Diseases, Volume 232. Abstract
submitted by kickingbird at Oct, 18, 2025 from The Journal of Infectious Diseases, Volume 232 (via https://academic.oup.com/jid/article/232/Supplement_3/S243/8)
Antivirals form a foundation for protecting immunocompromised individuals (ICIs) from influenza complications. Neuraminidase inhibitors have demonstrated benefit for both prophylaxis and treatment in ICIs, ... Lindsey E Hastings, Edward P Acosta, David W Kimbe. Influenza Antiviral Pharmacokinetic-Pharmacodynamic Relationships in Pregnancy, Infancy, and Early Childhood. The Journal of Infectious Diseases, Volume 232. Abstract
submitted by kickingbird at Oct, 18, 2025 from The Journal of Infectious Diseases, Volume 232 (via https://academic.oup.com/jid/article/232/Supplement_3/S286/8)
Owing to its decades of use among patients of all ages and health conditions, oseltamivir has the most widely described pharmacokinetics (PK) and pharmacodynamics (PD) of all the modern influenza antivirals. ... Jahid MJ, Owsiany MC, Smith LM, Foreman BM, Cao Z,. Serological Evidence of Exposure to Eurasian-Lineage HPAI H5N1 Clade 2.3.4.4b in Wild Mammals in Ohio, USA, 2024-2025. Viruses. 2025; 17(10):1388. Abstract
submitted by kickingbird at Oct, 18, 2025 from Viruses. 2025; 17(10):1388 (via https://www.mdpi.com/1999-4915/17/10/1388)
The Goose/Guandong lineage of highly pathogenic avian influenza virus [A/Goose/Guangdong/1/1996(H5N1)] is the progenitor of the currently circulating Eurasian-lineage highly pathogenic avian influenza ... Puttahonnappa, S.K., Anandakumar, J., Barman, N.N.. Investigating environmental determinants and spatiotemporal dynamics of highly pathogenic avian influenza H5N1 outbreaks in India through machine learning. Sci Rep 15, 36132 (2025). Abstract
submitted by kickingbird at Oct, 18, 2025 from Sci Rep 15, 36132 (2025) (via https://link.springer.com/article/10.1038/s41598-025-96765-2)
Avian Influenza (AI), caused by highly pathogenic strains of influenza viruses, poses a significant threat to poultry populations and public health worldwide. This study offers a comprehensive evaluation ... Gaglani M, Raiyani C, Murthy K, Smith M, da Graca. Absolute and Relative Effectiveness of Cell- and Egg-based Quadrivalent Inactivated Influenza Vaccine Products from 2014-2015 to 2018-2019 seasons, U.S. Flu VE Network. Clin Infect Dis. 2025 Oct 16:ciaf579. Abstract
submitted by kickingbird at Oct, 18, 2025 from Clin Infect Dis. 2025 Oct 16:ciaf579 (via https://academic.oup.com/cid/advance-article/doi/10.1093/cid)
Background: Estimates of annual effectiveness of influenza vaccination combine multiple vaccine types. Reports of brand/product-specific vaccine effectiveness (VE) of egg- and cell-culture based quadrivalent ... Liu Z, Guo J, Zhang C, Ding Y, Sun S, Yao B, Xing. Computational Discovery of Potent Nucleoprotein Inhibitors for Influenza A Virus: Validation Through QM/MM Analysis and Experimental Binding Assays. Molecules. 2025; 30(19):3960. Abstract
submitted by kickingbird at Oct, 17, 2025 from Molecules. 2025; 30(19):3960 (via https://www.mdpi.com/1420-3049/30/19/3960)
This study employed an integrated computational approach to discover novel nucleoprotein (NP) inhibitors for influenza A virus (IAV). Beginning with virtual screening of over 10 million compounds using ... Hepp C, Zhao Q, Robb N, Fodor E, Kapanidis AN. High-throughput single-virion DNA-PAINT reveals structural diversity, cooperativity, and flexibility during selective packaging in influenza. Nucleic Acids Res. 2025 Oct 14;53(19):gkaf1020. Abstract
submitted by kickingbird at Oct, 17, 2025 from Nucleic Acids Res. 2025 Oct 14;53(19):gkaf1020 (via https://academic.oup.com/nar/article/53/19/gkaf1020/8285782)
Influenza A, a negative-sense RNA virus, has a genome that consists of eight single-stranded RNA segments. Influenza co-infections can result in reassortant viruses that contain gene segments from multiple ... Hui DSC, Chan KKP. Host Immunomodulatory Interventions in Severe Influenza. J Infect Dis. 2025 Oct 17;232(Supplement_3):S262-S. Abstract
submitted by kickingbird at Oct, 17, 2025 from J Infect Dis. 2025 Oct 17;232(Supplement_3):S262-S (via https://academic.oup.com/jid/article/232/Supplement_3/S262/8)
Currently, no immunomodulatory agents have been conclusively shown to benefit severe influenza. The World Health Organization conditionally advises against the use of systemic corticosteroids, macrolides, ... Takashita E, Wolfe CR, Jones JC. Laboratory Methods for Monitoring Influenza Antiviral Resistance. J Infect Dis. 2025 Oct 17;232(Supplement_3):S273-. Abstract
submitted by kickingbird at Oct, 17, 2025 from J Infect Dis. 2025 Oct 17;232(Supplement_3):S273- (via https://academic.oup.com/jid/article-abstract/232/Supplement)
Monitoring antiviral susceptibility is an essential component of virologic surveillance conducted by laboratories participating in the World Health Organization (WHO) Global Influenza Surveillance and ... Yang J, Sun J, Zhao D, Liu J, Ma M, Wang Q, Bi Y. Reassortment risk of clade 2.3.4.4b H5N1 with avian H9N2 and human H3N2 and H1N1 influenza A viruses. Sci Bull (Beijing). 2025 Sep 23:S2095-9273(25)0097. Abstract
submitted by kickingbird at Oct, 17, 2025 from Sci Bull (Beijing). 2025 Sep 23:S2095-9273(25)0097 (via https://www.sciencedirect.com/science/article/abs/pii/S20959)
Since 2021, clade 2.3.4.4b H5N1 highly pathogenic avian influenza viruses(AIVs) have become the dominant strain responsible for the ongoing panzootics in birds worldwide, causing unprecedented deaths of ... Han X, Ma R, Ma X, Chen H, Zhao T, Liu X, Zhu L, Y. Development of a broad-spectrum nasal live attenuated influenza vaccine based on mosaic antigen design against influenza B viruses. Emerg Microbes Infect. 2025 Oct 15:2576141. Abstract
submitted by kickingbird at Oct, 17, 2025 from Emerg Microbes Infect. 2025 Oct 15:2576141 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Influenza B virus (IBV) causes significant seasonal disease burden, and frequent antigenic drift limits the effectiveness of conventional vaccines. To address this, we designed mosaic hemagglutinin (HA) ... Chen LL, Ip JD, Chan WM, Lam SJ, Leung RC, Yip CC,. Enhanced replication of a contemporary avian influenza A H9N2 virus in human respiratory organoids. Emerg Microbes Infect. 2025 Oct 16:2576574. Abstract
submitted by kickingbird at Oct, 17, 2025 from Emerg Microbes Infect. 2025 Oct 16:2576574 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
H9N2 is currently the second most common avian influenza A virus subtype infecting humans. Monitoring viral phenotypic and genotypic adaptation to humans is crucial for risk assessment. Here, we compared ... Kok, A., Wilks, S.H., Tureli, S. et al. A vaccine central in A(H5) influenza antigenic space confers broad immunity. Nature (2025). Abstract
submitted by kickingbird at Oct, 16, 2025 from Nature (2025) (via https://link.springer.com/article/10.1038/s41586-025-09626-3)
Highly pathogenic avian influenza A(H5) viruses globally impact wild and domestic birds, and have caused severe infections in mammals, including humans, underscoring their pandemic potential1,2,3,4,5. ... Lasrado N, Wang L, Liu J, R?ssler A, Chaudhari J,. An intramuscular prime and mucosal boost vaccine regimen protects against lethal clade 2.3.4.4b H5N1 challenge in cynomolgus macaques. Sci Transl Med. 2025 Oct 15;17(820):eady2282. Abstract
submitted by kickingbird at Oct, 16, 2025 from Sci Transl Med. 2025 Oct 15;17(820):eady2282 (via https://www.science.org/doi/10.1126/scitranslmed.ady2282)
The H5N1 clade 2.3.4.4b avian influenza virus outbreak in poultry and dairy cattle is a potential pandemic threat for humans. A safe and effective H5N1 influenza vaccine will be needed if the virus acquires ... Ramos-Martínez JC, Ramos-Martínez I, Saavedra-Mont. Global seroprevalence and prevalence of infection of influenza in dogs and cats: A systematic review and meta-analysis. Prev Vet Med. 2025 Oct 11;246:106716. Abstract
submitted by kickingbird at Oct, 16, 2025 from Prev Vet Med. 2025 Oct 11;246:106716 (via https://www.sciencedirect.com/science/article/abs/pii/S01675)
This study aimed to estimate the prevalence and seroprevalence of influenza A virus in dogs and cats though a systematic review and meta-analysis was performed following PRISMA guidelines. A total of 79 ... Christin Hennig, etc.,al. High serological barriers may contribute to restricted Influenza-A-virus transmission between pigs and humans. One Health. Abstract
submitted by kickingbird at Oct, 16, 2025 from One Health (via https://www.sciencedirect.com/science/article/pii/S235277142)
Influenza A viruses (IAV) circulate in both humans and pigs, with bidirectional transmission potentially driving viral evolution. Despite frequent contact and genetic compatibility, observed cross-species ... Vuong N. Bui, etc.,al. Active Surveillance for Emerging Influenza A Viruses - Findings from a One Health Study in Vietnam‘s Live Bird Markets. International Journal of Infectious Diseases. Abstract
submitted by kickingbird at Oct, 16, 2025 from International Journal of Infectious Diseases (via https://www.sciencedirect.com/science/article/pii/S120197122)
ObjectivesLive bird markets (LBMs) in Asia have often been the source of human infections with avian influenza virus (AIV).MethodsFrom July 2021 to August 2023, we employed a One Health approach in conducting ... Akeno Tsuneki-Tokunaga, etc.,al. Epidemic Influenza Virus Strains with High Growth Capability induce Severe Inflammatory Response in Vivo. Virology. Abstract
submitted by kickingbird at Oct, 16, 2025 from Virology (via https://www.sciencedirect.com/science/article/abs/pii/S00426)
Influenza epidemics occur worldwide and impose a substantial socioeconomic burden. In our previous studies, epidemic influenza virus strains isolated from seasonal influenza patient specimens exhibited ... 9542 items, 20/Page, Page[12/478][|<<] [|<] [11] [12] [13] [14] [15] [16] [17] [18] [19] [20] [>|] [>>|] |
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