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2025-12-5 22:03:09
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Graziosi, G.; Lupini, C.; Catelli, E.; Carnaccini,. Highly Pathogenic Avian Influenza (HPAI) H5 Clade 2.3.4.4b Virus Infection in Birds and Mammals. Animals 2024, 14, 1372.  Abstract  
submitted by kickingbird at May, 5, 2024 from Animals 2024, 14, 1372 (via https://www.mdpi.com/2076-2615/14/9/1372)
Avian influenza viruses (AIVs) are highly contagious respiratory viruses of birds, leading to significant morbidity and mortality globally and causing substantial economic losses to the poultry industry ...

Amin F, Mukhtar N, Ali M, Shehzad R, Ayub S, Aslam. Mapping Genetic Markers Associated with Antigenicity and Host Range in H9N2 Influenza A Viruses Infecting Poultry in Pakistan. Avian Dis. 2024 Mar;68(1):43-51.  Abstract  
submitted by kickingbird at May, 4, 2024 from Avian Dis. 2024 Mar;68(1):43-51 (via https://bioone.org/journals/avian-diseases/volume-68/issue-1)
The aim of the current study was to map the genetic diversity in the haemagglutinin (HA) glycoprotein of influenza A viruses (IAVs) of the H9N2 subtype. Twenty-five H9N2 IAVs were isolated from broiler ...

Lehto KM, L?nsivaara A, Hyder R, Luomala O, Lippon. Wastewater-based surveillance is an efficient monitoring tool for tracking influenza A in the community. Water Res. 2024 Apr 20;257:121650.  Abstract  
submitted by kickingbird at May, 4, 2024 from Water Res. 2024 Apr 20;257:121650 (via https://www.sciencedirect.com/science/article/pii/S004313542)
Around the world, influenza A virus has caused severe pandemics, and the risk of future pandemics remains high. Currently, influenza A virus surveillance is based on the clinical diagnosis and reporting ...

Ahrens AK, Jónsson SR, Svansson V, Brugger B, Beer. Iceland: an underestimated hub for the spread of high-pathogenicity avian influenza viruses in the North Atlantic. J Gen Virol. 2024 May;105(5).  Abstract  
submitted by kickingbird at May, 4, 2024 from J Gen Virol. 2024 May;105(5) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
High-pathogenicity avian influenza viruses (HPAIVs) of the goose/Guangdong lineage are enzootically circulating in wild bird populations worldwide. This increases the risk of entry into poultry production ...

Uyeki TM, Milton S, Abdul Hamid C, et al. Highly Pathogenic Avian Influenza A(H5N1) Virus Infection in a Dairy Farm Worker. New England Journal of Medicine.  Abstract  
submitted by kickingbird at May, 3, 2024 from New England Journal of Medicine (via https://www.nejm.org/doi/full/10.1056/NEJMc2405371)
Sporadic human infections with highly pathogenic avian influenza (HPAI) A(H5N1) virus, with a wide spectrum of clinical severity and a cumulative case fatality of more than 50%, have been reported in 23 ...

Thao-Quyen Nguyen, etc.,al. [preprint] Emergence and interstate spread of highly pathogenic avian influenza A(H5N1) in dairy cattle. https://doi.org/10.1101/2024.05.01.591751.  Abstract  
submitted by kickingbird at May, 2, 2024 from https://doi.org/10.1101/2024.05.01.591751 (via https://www.biorxiv.org/content/10.1101/2024.05.01.591751v1)
Highly pathogenic avian influenza (HPAI) viruses cross species barriers and have the potential to cause pandemics. In North America, HPAI A(H5N1) viruses related to the goose/Guangdong 2.3.4.4b hemagglutinin ...

Pinotti, F., Kohnle, L., Louren?o, J. et al. Modelling the transmission dynamics of H9N2 avian influenza viruses in a live bird market. Nat Commun 15, 3494 (2024).  Abstract  
submitted by kickingbird at May, 2, 2024 from Nat Commun 15, 3494 (2024) (via https://www.nature.com/articles/s41467-024-47703-9)
H9N2 avian influenza viruses (AIVs) are a major concern for the poultry sector and human health in countries where this subtype is endemic. By fitting a model simulating H9N2 AIV transmission to data from ...

Menon, T., Illing, P.T., Chaurasia, P. et al. CD8+ T-cell responses towards conserved influenza B virus epitopes across anatomical sites and age. Nat Commun 15, 3387 (2024).  Abstract  
submitted by kickingbird at Apr, 30, 2024 from Nat Commun 15, 3387 (2024) (via https://www.nature.com/articles/s41467-024-47576-y)
Influenza B viruses (IBVs) cause substantive morbidity and mortality, and yet immunity towards IBVs remains understudied. CD8+ T-cells provide broadly cross-reactive immunity and alleviate disease severity ...

Hall V, Cardona C, Mendoza K, Torchetti M, Lantz K. Surveillance for highly pathogenic avian influenza A (H5N1) in a raptor rehabilitation center-2022. PLoS One. 2024 Apr 29;19(4):e0299330.  Abstract  
submitted by kickingbird at Apr, 30, 2024 from PLoS One. 2024 Apr 29;19(4):e0299330 (via https://journals.plos.org/plosone/article?id=10.1371/journal)
An ongoing, severe outbreak of highly pathogenic avian influenza virus (HPAI) A H5N1 clade 2.3.4.4b has been circulating in wild and domestic bird populations throughout the world, reaching North America ...

Marlene K Wolfe, Dorothea Duong, etc.,al. [preprint]Detection of hemagglutinin H5 influenza A virus sequence in municipal wastewater solids at wastewater treatment plants with increases in influenza A in spring, 2024. doi.org/10.1101/2024.04.26.24306409.  Abstract  
submitted by kickingbird at Apr, 30, 2024 from doi.org/10.1101/2024.04.26.24306409 (via https://www.medrxiv.org/content/10.1101/2024.04.26.24306409v)
Prospective influenza A (IAV) RNA monitoring at 190 wastewater treatment plants across the US identified increases in IAV RNA concentrations at 59 plants in spring 2024, after the typical seasonal influenza ...

Burrough ER, Magstadt DR, Petersen B, Timmermans S. Highly Pathogenic Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Domestic Dairy Cattle and Cats, United States, 2024. Emerg Infect Dis. 2024.  Abstract  
submitted by kickingbird at Apr, 30, 2024 from Emerg Infect Dis. 2024 (via https://wwwnc.cdc.gov/eid/article/30/7/24-0508_article)
We report highly pathogenic avian influenza A(H5N1) virus in dairy cattle and cats in Kansas and Texas, United States, which reflects the continued spread of clade 2.3.4.4b viruses that entered the country ...

Valenzuela-Sánchez F, Valenzuela-Méndez B, Rodrígu. Latest developments in early diagnosis and specific treatment of severe influenza infection. J Intensive Med. 2023 Dec 19;4(2):160-174.  Abstract  
submitted by kickingbird at Apr, 29, 2024 from J Intensive Med. 2023 Dec 19;4(2):160-174 (via https://www.sciencedirect.com/science/article/pii/S2667100X2)
Influenza pandemics are unpredictable recurrent events with global health, economic, and social consequences. The objective of this review is to provide an update on the latest developments in early diagnosis ...

Qui NH, Thu NTA, Linh NT. Factors affecting highly pathogenic avian influenza vaccination practices at poultry farms in Tra Vinh, Vietnam. Open Vet J. 2024 Mar;14(3):794-804.  Abstract  
submitted by kickingbird at Apr, 29, 2024 from Open Vet J. 2024 Mar;14(3):794-804 (via https://www.ejmanager.com/mnstemps/100/100-1698640057.pdf?t=)
Background: The increased number of cases of highly pathogenic avian influenza (HPAI) as a zoonosis has raised concerns in terms of poultry and human health. Farmers' preventive practices are an effective ...

Madelyn Krunkosky, etc.,al. Establishment of Swine Primary Nasal, Tracheal, and Bronchial Epithelial Cell Culture Models for the Study of Influenza Virus Infection. Journal of Virological Methods.  Abstract  
submitted by kickingbird at Apr, 28, 2024 from Journal of Virological Methods (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
We established primary porcine nasal, tracheal, and bronchial epithelial cells that recapitulate the physical and functional properties of the respiratory tract and have the ability to fully differentiate. ...

Gonzalo Tomás, etc.,al. Highly pathogenic avian influenza H5N1 virus infections in pinnipeds and seabirds in Uruguay: implications for bird-mammal transmission in South America. Virus Evolution, veae031.  Abstract  
submitted by kickingbird at Apr, 28, 2024 from Virus Evolution, veae031 (via https://academic.oup.com/ve/advance-article/doi/10.1093/ve/v)
The highly pathogenic avian influenza viruses of the clade 2.3.4.4b have caused unprecedented deaths in South American wild birds, poultry, and marine mammals. In September 2023, pinnipeds and seabirds ...

Se-Hee An, Na-Yeong Kim, etc.,al. Development and evaluation of a multiplex real-time RT-PCR assay for simultaneous detection of H5, H7, and H9 subtype avian influenza viruses. Journal of Virological Methods.  Abstract  
submitted by kickingbird at Apr, 28, 2024 from Journal of Virological Methods (via https://www.sciencedirect.com/science/article/abs/pii/S01660)
H5, H7 and H9 are the major subtypes of avian influenza virus (AIV) that cause economic losses in the poultry industry and sporadic zoonotic infection. Early detection of AIV is essential for preventing ...

Siru Lin, Junhong Chen, etc.,al. Evolutionary dynamics and comparative pathogenicity of clade 2.3.4.4b H5 subtype avian influenza viruses, China, 2021~2022. Virologica Sinica.  Abstract  
submitted by kickingbird at Apr, 28, 2024 from Virologica Sinica (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
The recent concurrent emergence of H5N1, H5N6, and H5N8 avian influenza viruses (AIVs) has caused significant avian mortality globally. Since 2020, frequent human-animal interactions have been documented. ...

Zhi, Y.; Zhao, X.; Liu, Z.; Shen, G.; Zhang, T.; Z. Oxymatrine Modulation of TLR3 Signaling: A Dual-Action Mechanism for H9N2 Avian Influenza Virus Defense and Immune Regulation. Molecules 2024, 29, 1945.  Abstract  
submitted by kickingbird at Apr, 27, 2024 from Molecules 2024, 29, 1945 (via https://www.mdpi.com/1420-3049/29/9/1945)
In our research, we explored a natural substance called Oxymatrine, found in a traditional Chinese medicinal plant, to fight against a common bird flu virus known as H9N2. This virus not only affects birds ...

Sanchez, P.L.; Andre, G.; Antipov, A.; Petrovsky,. Advax-SM?-Adjuvanted COBRA (H1/H3) Hemagglutinin Influenza Vaccines. Vaccines 2024, 12, 455.  Abstract  
submitted by kickingbird at Apr, 27, 2024 from Vaccines 2024, 12, 455 (via https://www.mdpi.com/2076-393X/12/5/455)
Adjuvants enhance immune responses stimulated by vaccines. To date, many seasonal influenza vaccines are not formulated with an adjuvant. In the present study, the adjuvant Advax-SM? was combined with ...

Xia, C.; Wang, T.; Hahm, B. Triggering Degradation of Host Cellular Proteins for Robust Propagation of Influenza Viruses. Int. J. Mol. Sci. 2024, 25, 4677.  Abstract  
submitted by kickingbird at Apr, 27, 2024 from Int. J. Mol. Sci. 2024, 25, 4677 (via https://www.mdpi.com/1422-0067/25/9/4677)
Following infection, influenza viruses strive to establish a new host cellular environment optimized for efficient viral replication and propagation. Influenza viruses use or hijack numerous host factors ...

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