WANG W, Suguitan AL Jr, Zengel J, Chen Z, et al.. Generation of recombinant pandemic H1N1 influenza virus with the HA cleavable by bromelain and identification of the residues influencing HA bromelain cleavage. Vaccine. 2011. Abstract
submitted by kickingbird at Dec, 21, 2011 from Vaccine. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22172510)
The proteolytic enzyme bromelain has been traditionally used to cleave the hemagglutinin (HA) protein at the C-terminus of the HA2 region to release the HA proteins from influenza virions. The bromelain ... MA W, Belisle SE, Mosier D, Li X, et al.. 2009 pandemic H1N1 influenza virus causes disease and upregulation of genes related to inflammatory and immune responses, cell death, and lipid metabolism in pigs. J Virol. 2011;85:11626-37. Abstract
submitted by kickingbird at Dec, 21, 2011 from J Virol. 2011;85:11626-37 (via http://www.ncbi.nlm.nih.gov/pubmed/21900171)
There exists limited information about whether adaptation is needed for cross-species transmission of the 2009 pandemic H1N1 influenza virus (pH1N1). Here, we compare the pathogenesis of two pH1N1 viruses, ... LIN L, Li Y, Pyo HM, Lu X, et al.. Identification of RNA helicase A as a cellular factor that interacts with influenza A NS1 protein and its role in virus life cycle. J Virol. 2011. Abstract
submitted by kickingbird at Dec, 21, 2011 from J Virol. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22171255)
Influenza A virus NS1 protein has multiple functions in the infected cell during the virus life cycle. Identification of novel cellular factors that interact with NS1 and understanding their functions ... ABED Y, Pizzorno A, Hamelin ME, Leung A, et al. The 2009 pandemic H1N1 D222G hemagglutinin mutation alters receptor specificity and increases virulence in mice but not in ferrets.. J Infect Dis. 2011;204:1008-16. Abstract
submitted by kickingbird at Dec, 21, 2011 from J Infect Dis. 2011;204:1008-16 (via http://www.ncbi.nlm.nih.gov/pubmed/21881115)
BACKGROUND:
The D222G (H1 numbering) hemagglutinin (HA) mutation within the receptor-binding site was detected with higher frequencies in severe cases of 2009 pandemic H1N1 (pH1N1) infections. We investigated ... MAINES TR, Belser JA, Gustin KM, van Hoeven N, et. Local Innate Immune Responses and Influenza Virus Transmission and Virulence in Ferrets.. J Infect Dis. 2011. Abstract
submitted by kickingbird at Dec, 21, 2011 from J Infect Dis. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22158704)
Host innate immunity is the first line of defense against invading pathogens, including influenza viruses. Ferrets are well recognized as the best model of influenza virus pathogenesis and transmission, ... VANDERMEER ML, Thomas AR, Kamimoto L, Reingold A,. Association Between Use of Statins and Mortality Among Patients Hospitalized With Laboratory-Confirmed Influenza Virus Infections: A Multistate Study.. J Infect Dis. 2011.. Abstract
submitted by kickingbird at Dec, 21, 2011 from J Infect Dis. 2011. (via http://www.ncbi.nlm.nih.gov/pubmed/22170954)
Background.?Statins may have anti-inflammatory and immunomodulatory effects that could reduce the risk of mortality from influenza virus infections. Methods.?The Centers for Disease Control and Prevention's ... AL-GARAWI A, Husain M, Ilieva D, Humbles AA, et al. Shifting of Immune Responsiveness to House Dust Mite by Influenza A Infection:Genomic Insights.. J Immunol. 2011. Abstract
submitted by kickingbird at Dec, 21, 2011 from J Immunol. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22174454)
Respiratory viral infections have been associated with an increased incidence of allergic asthma. However, the mechanisms by which respiratory infections facilitate allergic airway disease are incompletely ... KAMINSKI MM, Ohnemus A, Cornitescu M, Staeheli P,. Plasmacytoid dendritic cells and TLR7-dependent signaling promote efficient protection of mice against highly virulent influenza A virus. J Gen Virol. 2011.. Abstract
submitted by kickingbird at Dec, 21, 2011 from J Gen Virol. 2011. (via http://www.ncbi.nlm.nih.gov/pubmed/22170637)
Type I and type III interferons (IFNs) elicit protective antiviral immune responses during influenza virus infection. Although many cell types can synthesize IFN in response to virus infection, it remains ... VEHRESCHILD JJ, Brockelmann PJ, Bangard C, Verheye. Pandemic 2009 influenza A(H1N1) virus infection coinciding with invasive pulmonary aspergillosis in neutropenic patients. Epidemiol Infect. 2011.. Abstract
submitted by kickingbird at Dec, 21, 2011 from Epidemiol Infect. 2011. (via http://www.ncbi.nlm.nih.gov/pubmed/22152763)
SUMMARYIn patients receiving anti-neoplastic chemotherapy, the impact of influenza on the incidence of invasive pulmonary aspergillosis (IPA) remains unknown. We matched data of the Cologne Cohort of Neutropenic ... A. C. Hurt et al.. Mutations I117V and I117M and Oseltamivir Sensitivity of Pandemic (H1N1) 2009 Viruses. Emerg Infect Dis 2011 Dec 19. Full Text
submitted by kickingbird at Dec, 20, 2011 from Emerg Infect Dis 2011 Dec 19 (via http://wwwnc.cdc.gov/eid/)
11-1079-ahead_of_print.pdf Storms AD, Gubareva V, Su S, et al. Oseltamivir-resistant pandemic (H1N1) 2009 virus infections, United States, 2010-11. Emerg Infect Dis 2011 Dec 19. Full Text
submitted by kickingbird at Dec, 20, 2011 from Emerg Infect Dis 2011 Dec 19 (via http://wwwnc.cdc.gov/eid/)
11-1466-ahead_of_print.pdf Hurt AC, Chotpitayasunondh T, Cox N, et al.. Antiviral resistance during the 2009 influenza A H1N1 pandemic: public health, laboratory, and clinical perspectives. Lancet Infect Dis 2011 Dec 19. Abstract
submitted by kickingbird at Dec, 20, 2011 from Lancet Infect Dis 2011 Dec 19 (via http://www.thelancet.com/journals/laninf/article/PIIS1473-30)
Influenza A H1N1 2009 virus caused the first pandemic in an era when neuraminidase inhibitor antiviral drugs were available in many countries. The experiences of detecting and responding to resistance ... ROTH B, Mohr H, Enders M, Garten W, et al.. Isolation of influenza viruses in MDCK 33016PF cells and clearance of contaminating respiratory viruses. Vaccine. 2011. Abstract
submitted by kickingbird at Dec, 20, 2011 from Vaccine. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22119922)
This paper summarizes results obtained by multiplex PCR screening of human clinical samples for respiratory viruses and corresponding data obtained after passaging of virus-positive samples in MDCK 33016PF ... SAMMON CJ, McGrogan A, Snowball J, de Vries CS, et. Factors associated with uptake of seasonal and pandemic influenza vaccine among clinical risk groups in the UK: An analysis using the General Practice Research Database. Vaccine. 2011.. Abstract
submitted by kickingbird at Dec, 20, 2011 from Vaccine. 2011. (via http://www.ncbi.nlm.nih.gov/pubmed/22133511)
Abstract
BACKGROUND:
Influenza vaccine uptake rates are low compared with uptake rates of many other vaccines. It is unclear how this differs between risk groups in the population and between pandemic ... GILES BM, Bissel SJ, Craigo JK, Dealmeida DR, et a. Elicitation of anti-1918 influenza immunity early in life prevents morbidity and lower lung infection by 2009 pandemic H1N1 influenza in aged mice. J Virol. 2011. Abstract
submitted by kickingbird at Dec, 20, 2011 from J Virol. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22130546)
The "Spanish" influenza pandemic of 1918 was responsible for 40 to 50 million deaths and is antigenically similar to the swine lineage 2009 pandemic influenza virus. Emergence of the 2009 pandemic from ... KILLINGLEY B, Enstone JE, Greatorex J, Gilbert AS,. Use of a Human Influenza Challenge Model to Assess Person-to-Person Transmission: Proof-of-Concept Study. J Infect Dis. 2011.. Abstract
submitted by kickingbird at Dec, 20, 2011 from J Infect Dis. 2011. (via http://www.ncbi.nlm.nih.gov/pubmed/22131338)
Background.?Influenza transmission in humans remains poorly understood. In particular, the relative contribution of contact, large droplet, and aerosol transmission is unknown. The aims of this proof-of-concept ... SONG D, Moon H, An DJ, Jeong HY, et al.. A Novel Reassortant Canine H3N1 Influenza Virus between Pandemic H1N1 and Canine H3N2 Influenza Viruses in Korea. J Gen Virol. 2011. Abstract
submitted by kickingbird at Dec, 20, 2011 from J Gen Virol. 2011 (via http://www.ncbi.nlm.nih.gov/pubmed/22131311)
During recent canine influenza surveillance in South Korea, a novel canine influenza virus (CIV) H3N1 which was a putative reassortant between pandemic H1N1 2009 and H3N2 canine influenza viruses was isolated. ... Nobuhiro Takemae, Sujira Parchariyanon, Ruttapong. Swine influenza virus infection in different age groups of pigs in farrow-to-finish farms in Thailand. Virology Journal 2011, 8:537. Abstract
submitted by kickingbird at Dec, 15, 2011 from Virology Journal 2011, 8:537 (via http://www.virologyj.com/content/8/1/537/abstract)
Background
Understanding swine influenza virus (SIV) ecology has become more and more important from both the pig industry and public health points of views. However, the mechanism whereby SIV occurs ... Epstein S. T-Cell Immune Responses and Asymptomatic H5N1 Influenza Infection. J Infect Dis 2011. Abstract
submitted by kickingbird at Dec, 3, 2011 from J Infect Dis 2011 (via http://jid.oxfordjournals.org/content/early/2011/11/10/infdi)
Approximately 60% of people ill with influenza A virus subtype H5N1 infection die [1], a case fatality rate about 25 times worse than that during the 1918 pandemic [2]. It is hard to even imagine the devastation ... Powell TJ, Fox A, Peng Y, et al.. Identification of H5N1-Specific T-Cell Responses in a High-risk Cohort in Vietnam Indicates the Existence of Potential Asymptomatic Infections. J Infect Dis 2011. Abstract
submitted by kickingbird at Dec, 3, 2011 from J Infect Dis 2011 (via http://jid.oxfordjournals.org/content/early/2011/11/10/infdi)
Background.?Most reported human H5N1 viral infections have been severe and were detected after hospital admission. A case ascertainment bias may therefore exist, with mild cases or asymptomatic infections ... 7514 items, 20/Page, Page[283/376][|<<] [|<] [281] [282] [283] [284] [285] [286] [287] [288] [289] [290] [>|] [>>|] |
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