Zhu Y, Cong Y, Sun Y, Han J, Gai L, Yang T, Liu C,. Isolation and Identification of Novel Highly Pathogenic Avian Influenza Virus (H5N8) Subclade 2.3.4.4b from Geese in Northeastern China. Appl Environ Microbiol. 2023 Jan 5:e0157222. Abstract
submitted by kickingbird at Jan, 7, 2023 from Appl Environ Microbiol. 2023 Jan 5:e0157222 (via https://journals.asm.org/doi/10.1128/aem.01572-22)
H5N8, a highly pathogenic avian influenza, has become a new zoonotic threat in recent years. As of December 28, 2021, at least 3,206 H5N8 cases had been reported in wild birds and poultry worldwide. In ... Nemeth NM, Ruder MG, Poulson RL, Sargent R, Breedi. Bald eagle mortality and nest failure due to clade 2.3.4.4 highly pathogenic H5N1 influenza a virus. Sci Rep. 2023 Jan 5;13(1):191. Abstract
submitted by kickingbird at Jan, 7, 2023 from Sci Rep. 2023 Jan 5;13(1):191 (via https://www.nature.com/articles/s41598-023-27446-1)
The bald eagle (Haliaeetus leucocephalus) is a culturally and ecologically vital species in North America that embodies conservation success but continues to face threats that include emerging pathogens. ... Asher J, Lemenuel-Diot A, Clay M, Durham DP, Mier-. Novel modelling approaches to predict the role of antivirals in reducing influenza transmission. PLoS Comput Biol. 2023 Jan 6;19(1):e1010797. Abstract
submitted by kickingbird at Jan, 7, 2023 from PLoS Comput Biol. 2023 Jan 6;19(1):e1010797 (via https://journals.plos.org/ploscompbiol/article?id=10.1371/jo)
To aid understanding of the effect of antiviral treatment on population-level influenza transmission, we used a novel pharmacokinetic-viral kinetic transmission model to test the correlation between nasal ... Vandoorn E, Stadejek W, Leroux-Roels I, Leroux-Roe. Human Immunity and Susceptibility to Influenza A(H3) Viruses of Avian, Equine, and Swine Origin. Emerg Infect Dis. 2023 Jan;29(1):98-109. Abstract
submitted by kickingbird at Dec, 31, 2022 from Emerg Infect Dis. 2023 Jan;29(1):98-109 (via https://pubmed.ncbi.nlm.nih.gov/36573615/)
Influenza A viruses (IAVs) of subtype H3 that infect humans are antigenically divergent from those of birds, horses, and swine. Human immunity against these viruses might be limited, implying potential ... Edwards KM, Siegers JY, Wei X, Aziz A, Deng YM, Ya. Detection of Clade 2.3.4.4b Avian Influenza A(H5N8) Virus in Cambodia, 2021. Emerg Infect Dis. 2023 Jan;29(1):170-174. Abstract
submitted by kickingbird at Dec, 31, 2022 from Emerg Infect Dis. 2023 Jan;29(1):170-174 (via https://pubmed.ncbi.nlm.nih.gov/36573541/)
In late 2021, highly pathogenic avian influenza A(H5N8) clade 2.3.4.4b viruses were detected in domestic ducks in poultry markets in Cambodia. Surveillance, biosafety, and biosecurity efforts should be ... Zinyakov N, Andriyasov A, Zhestkov P, Kozlov A, Ni. Analysis of Avian Influenza (H5N5) Viruses Isolated in the Southwestern European Part of the Russian Federation in 2020-2021. Viruses. 2022 Dec 6;14(12):2725. Abstract
submitted by kickingbird at Dec, 27, 2022 from Viruses. 2022 Dec 6;14(12):2725 (via https://www.mdpi.com/1999-4915/14/12/2725)
In 2021, several isolates of the H5N5 avian influenza virus (AIV) were detected in Europe and the Russian Federation, which differed from those detected in 2020. Genetic analysis revealed a relationship ... Huang X, Yin G, Cai Y, Hu J, Huang J, Liu Q, Feng. Identification of Unique and Conserved Neutralizing Epitopes of Vestigial Esterase Domain in HA Protein of the H9N2 Subtype of Avian Influenza Virus. Viruses. 2022 Dec 8;14(12):2739. Abstract
submitted by kickingbird at Dec, 27, 2022 from Viruses. 2022 Dec 8;14(12):2739 (via https://www.mdpi.com/1999-4915/14/12/2739)
The H9N2 subtype of avian influenza virus (AIV) has been reported to infect not only birds, but also humans. The hemagglutinin (HA) protein is the main surface antigen of AIV and plays an important role ... Xiao YN, Yu FY, Xu Q, Gu J. Tropism and Infectivity of Pandemic Influenza A H1N1/09 Virus in the Human Placenta. Viruses. 2022 Dec 15;14(12):2807. Abstract
submitted by kickingbird at Dec, 27, 2022 from Viruses. 2022 Dec 15;14(12):2807 (via https://www.mdpi.com/1999-4915/14/12/2807)
Influenza virus infection in pregnant women may put the fetus at higher risk; however, to date, there has been no detailed research about the expression of influenza virus receptors in the human placenta. ... Antigua KJC, Baek YH, Choi WS, Jeong JH, Kim EH, O. Multiple HA substitutions in highly pathogenic avian influenza H5Nx viruses contributed to the change in the NA subtype preference. Virulence. 2022 Dec;13(1):990-1004. Abstract
submitted by kickingbird at Dec, 27, 2022 from Virulence. 2022 Dec;13(1):990-1004 (via https://www.tandfonline.com/doi/full/10.1080/21505594.2022.2)
Novel highly pathogenic avian influenza (HPAI) H5Nx viruses are predominantly circulating worldwide, with an increasing potential threat of an outbreak in humans. It remains largely unknown how the stably ... Zhang J, Wang X, Ding S, Ma K, Jiang Y, Guo Y, Zha. Key amino acid position 272 in neuraminidase determines the replication and virulence of H5N6 avian influenza virus in mammals. iScience. 2022 Nov 30;25(12):105693. Abstract
submitted by kickingbird at Dec, 27, 2022 from iScience. 2022 Nov 30;25(12):105693 (via https://www.cell.com/iscience/fulltext/S2589-0042(22)01966-6)
Avian influenza H5N6 virus not only wreaks economic havoc in the poultry industry but also threatens human health. Strikingly, as of August 2022, 78 human beings were infected with H5N6, and the spike ... Yu C, Ding W, Zhu L, Zhou Y, Dong Y, Li L, Liu J,. Screening and characterization of inhibitory vNAR targeting nanodisc-assembled influenza M2 proteins. iScience. 2022 Dec 5;26(1):105736. Abstract
submitted by kickingbird at Dec, 27, 2022 from iScience. 2022 Dec 5;26(1):105736 (via https://www.cell.com/iscience/fulltext/S2589-0042(22)02009-0)
Influenza A virus poses a constant challenge to human health. The highly conserved influenza matrix-2 (M2) protein is an attractive target for the development of a universal antibody-based drug. However, ... Chang P, Lukosaityte D, Sealy JE, Rijal P, Sadeyen. Antigenic Characterization of Human Monoclonal Antibodies for Therapeutic Use against H7N9 Avian Influenza Virus. J Virol. 2022 Dec 21:e0143122. Abstract
submitted by kickingbird at Dec, 22, 2022 from J Virol. 2022 Dec 21:e0143122 (via https://journals.asm.org/doi/10.1128/jvi.01431-22)
Since 2013, H7N9 avian influenza viruses (AIVs) have caused more than 1,500 human infections and the culling of millions of poultry. Despite large-scale poultry vaccination, H7N9 AIVs continue to circulate ... Wang Q, Zeng X, Tan S, Lan L, Wang X, Lai Z, Liu Z. Pathogenicity and anti-infection immunity of animal H3N2 and H6N6 subtype influenza virus cross-species infection with tree shrews. Virus Res. 2022 Dec 18:199027. Abstract
submitted by kickingbird at Dec, 22, 2022 from Virus Res. 2022 Dec 18:199027 (via https://www.sciencedirect.com/science/article/pii/S016817022)
Animal influenza viruses can spread across species and pose a fatal threat to human health due to the high pathogenicity and mortality. Animal models are crucial for studying cross-species infection and ... Stadlbauer D, McMahon M, Turner HL, Zhu X, Wan H,. Antibodies targeting the neuraminidase active site inhibit influenza H3N2 viruses with an S245N glycosylation site. Nat Commun. 2022 Dec 21;13(1):7864. Abstract
submitted by kickingbird at Dec, 22, 2022 from Nat Commun. 2022 Dec 21;13(1):7864 (via https://www.nature.com/articles/s41467-022-35586-7)
Contemporary influenza A H3N2 viruses circulating since 2016 have acquired a glycosylation site in the neuraminidase in close proximity to the enzymatic active site. Here, we investigate if this S245N ... Guinat C, Valenzuela Agüí C, Vaughan TG, Scire J,. Disentangling the role of poultry farms and wild birds in the spread of highly pathogenic avian influenza virus in Europe. Virus Evol. 2022 Aug 18;8(2):veac073. Abstract
submitted by kickingbird at Dec, 21, 2022 from Virus Evol. 2022 Aug 18;8(2):veac073 (via https://academic.oup.com/ve/article/8/2/veac073/6671198)
In winter 2016-7, Europe was severely hit by an unprecedented epidemic of highly pathogenic avian influenza viruses (HPAIVs), causing a significant impact on animal health, wildlife conservation, and livestock ... Gaudino M, Chiapponi C, Moreno A, Zohari S, O&acut. Evolutionary and temporal dynamics of emerging influenza D virus in Europe (2009-22). Virus Evol. 2022 Sep 1;8(2):veac081. Abstract
submitted by kickingbird at Dec, 21, 2022 from Virus Evol. 2022 Sep 1;8(2):veac081 (via https://academic.oup.com/ve/article/8/2/veac081/6679728)
Influenza D virus (IDV) is an emerging influenza virus that was isolated for the first time in 2011 in the USA from swine with respiratory illness. Since then, IDV has been detected worldwide in different ... Gouma S, Furey C, Santos JJS, Parkhouse K, Weirick. Nucleoside-Modified mRNA-Based Influenza Vaccines Circumvent Problems Associated with H3N2 Vaccine Strain Egg Adaptation. J Virol. 2022 Dec 19:e0172322. Abstract
submitted by kickingbird at Dec, 21, 2022 from J Virol. 2022 Dec 19:e0172322 (via https://journals.asm.org/doi/10.1128/jvi.01723-22)
Most human influenza vaccine antigens are produced in fertilized chicken eggs. Recent H3N2 egg-based vaccine antigens have limited effectiveness, partially due to egg-adaptive substitutions that alter ... Chiba S, Hatta M, Pattinson D, Yasuhara A, Neumann. Ferret model to mimic the sequential exposure of humans to historical H3N2 influenza viruses. Vaccine. 2022 Dec 12:S0264-410X(22)01518-3. Abstract
submitted by kickingbird at Dec, 17, 2022 from Vaccine. 2022 Dec 12:S0264-410X(22)01518-3 (via https://www.sciencedirect.com/science/article/pii/S0264410X2)
Mutations accumulate in influenza A virus proteins, especially in the main epitopes on the virus surface glycoprotein hemagglutinin (HA). For influenza A(H3N2) viruses, in particular, the antigenicity ... Noisumdaeng P, Phadungsombat J, Weerated S, Wiriya. Genetic evolution of hemagglutinin and neuraminidase genes of H5N1 highly pathogenic avian influenza viruses in Thailand. PeerJ. 2022 Nov 30;10:e14419. Abstract
submitted by kickingbird at Dec, 17, 2022 from PeerJ. 2022 Nov 30;10:e14419 (via https://peerj.com/articles/14419/)
Background: Ongoing outbreaks of H5N1 highly pathogenic avian influenza (HPAI) viruses and the emergence of the genetic-related hemagglutinin (HA) gene of reassortant H5Nx viruses currently circulating ... Zhang B, Huang W, Pei S, Zeng J, Shen W, Wang D, W. Mechanisms for the circulation of influenza A(H3N2) in China: A spatiotemporal modelling study. PLoS Pathog. 2022 Dec 16;18(12):e1011046.. Abstract
submitted by kickingbird at Dec, 17, 2022 from PLoS Pathog. 2022 Dec 16;18(12):e1011046. (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Circulation of seasonal influenza is the product of complex interplay among multiple drivers, yet characterizing the underlying mechanism remains challenging. Leveraging the diverse seasonality of A(H3N2) ... 5156 items, 20/Page, Page[27/258][|<<] [|<] [21] [22] [23] [24] [25] [26] [27] [28] [29] [30] [>|] [>>|] |
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