LIU WC, Lin YL, Spearman M, Cheng PY, et al. Influenza Hemagglutinin Glycoproteins with Different N-glycan Patterns Activate Dendritic Cells in Vitro. J Virol. 2016 Apr 20. pii: JVI.00452-16.. Abstract
submitted by kickingbird at Apr, 28, 2016 from J Virol. 2016 Apr 20. pii: JVI.00452-16. (via http://www.ncbi.nlm.nih.gov/pubmed/27099319)
Influenza HA N-glycans serve important regulatory roles in the control of virus virulence, antigenicity, receptor-binding specificity, and viral immune escape. Considered essential for controlling innate ... FUDO S, Yamamoto N, Nukaga M, Odagiri T, et al. Two Distinctive Binding Modes of Endonuclease Inhibitors to the N-Terminal Region of Influenza Virus Polymerase Acidic Subunit. Biochemistry. 2016 Apr 26. Abstract
submitted by kickingbird at Apr, 28, 2016 from Biochemistry. 2016 Apr 26 (via http://www.ncbi.nlm.nih.gov/pubmed/27088785)
Influenza viruses are global threat to humans, and the development of new antiviral agents are still demanded to prepare for pandemics and to overcome the emerging resistance to the current drugs. Influenza ... WU H, Lu R, Peng X, Peng X, et al. Isolation and genetic characterization of novel reassortant H6N6 subtype avian influenza viruses isolated from chickens in eastern China. Arch Virol. 2016 Apr 21.. Abstract
submitted by kickingbird at Apr, 28, 2016 from Arch Virol. 2016 Apr 21. (via http://www.ncbi.nlm.nih.gov/pubmed/27101069)
H6 subtype avian influenza viruses (AIVs) possess the ability to cross the species barrier to infect mammals and pose a threat to human health. From June 2014 to July 2015, 12 H6N6 AIVs were isolated from ... M.C.W.Chan, etc.,al. Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo. PNAS 2016 ; published ahead of print March 14, 201. Abstract
submitted by kickingbird at Mar, 29, 2016 from PNAS 2016 ; published ahead of print March 14, 201 (via http://www.pnas.org/content/early/2016/03/09/1601911113)
Influenza can cause acute lung injury. Because immune responses often play a role, antivirals may not ensure a successful outcome. To identify pathogenic mechanisms and potential adjunctive therapeutic ... SONG MS, Kumar G, Shadrick WR, Zhou W, et al. Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor. Proc Natl Acad Sci U S A. 2016 Mar 14. pii: 201519. Abstract
submitted by kickingbird at Mar, 21, 2016 from Proc Natl Acad Sci U S A. 2016 Mar 14. pii: 201519 (via http://www.ncbi.nlm.nih.gov/pubmed/26976575)
The influenza endonuclease is an essential subdomain of the viral RNA polymerase. It processes host pre-mRNAs to serve as primers for viral mRNA and is an attractive target for antiinfluenza drug discovery. ... SHANKS GD, Burroughs SA, Sohn JD, Waters NC, et al. Enhanced risk of illness during the 1918 influenza pandemic after previous influenza-like illnesses in three military populations. Epidemiol Infect. 2016 Mar 9:1-6.. Abstract
submitted by kickingbird at Mar, 14, 2016 from Epidemiol Infect. 2016 Mar 9:1-6. (via http://www.ncbi.nlm.nih.gov/pubmed/26957052)
The reasons for the unprecedented mortality during the 1918 influenza pandemic remain poorly understood. We examined morbidity records from three military cohorts from years prior to and during the 1918 ... MARCHENKO VY, Susloparov IM, Kolosova NP, Goncharo. Highly pathogenic influenza H5N1 virus of clade 2.3.2.1c in Western Siberia. Arch Virol. 2016 Mar 3.. Abstract
submitted by kickingbird at Mar, 14, 2016 from Arch Virol. 2016 Mar 3. (via http://www.ncbi.nlm.nih.gov/pubmed/26935914)
In the spring of 2015, avian influenza virus surveillance in Western Siberia resulted in isolation of several influenza H5N1 virus strains. The strains were isolated from several wild bird species. Investigation ... GE F, Li X, Ju H, Yang D, et al. Genotypic evolution and antigenicity of H9N2 influenza viruses in Shanghai, China. Arch Virol. 2016 Mar 3. Abstract
submitted by kickingbird at Mar, 14, 2016 from Arch Virol. 2016 Mar 3 (via http://www.ncbi.nlm.nih.gov/pubmed/26935915)
H9N2 influenza viruses have been circulating in China since 1994, but a systematic investigation of H9N2 in Shanghai has not previously been undertaken. Here, using 14 viruses we isolated from poultry ... BELSER JA, Creager HM, Sun X, Gustin KM, et al. Mammalian pathogenesis and transmission of H7N9 influenza viruses from three waves, 2013-2015. J Virol. 2016 Feb 24. pii: JVI.00134-16. Abstract
submitted by kickingbird at Mar, 7, 2016 from J Virol. 2016 Feb 24. pii: JVI.00134-16 (via http://www.ncbi.nlm.nih.gov/pubmed/26912620)
Three waves of human infection with H7N9 influenza viruses have concluded to date, but only viruses within the first wave (isolated between March-September 2013) have been extensively studied in mammalian ... NAGESH PT, Husain M. Influenza A virus dysregulates host histone deacetylase 1 that inhibits viral infection in lung epithelial cells. J Virol. 2016 Feb 24. pii: JVI.00126-16. Abstract
submitted by kickingbird at Mar, 7, 2016 from J Virol. 2016 Feb 24. pii: JVI.00126-16 (via http://www.ncbi.nlm.nih.gov/pubmed/26912629)
Viruses dysregulate the host factors that inhibit virus infection. Here, we demonstrate that human enzyme, histone deacetylase 1 (HDAC1) is a new class of host factor that inhibits influenza A virus (IAV) ... OBOHO I, Reed C, Gargiullo P, Leon M, et al. Benefit of Early Initiation of Influenza Antiviral Treatment to Pregnant Women Hospitalized With Laboratory-Confirmed Influenza. J Infect Dis. 2016 Feb 3. pii: jiw033. Abstract
submitted by kickingbird at Mar, 7, 2016 from J Infect Dis. 2016 Feb 3. pii: jiw033 (via http://www.ncbi.nlm.nih.gov/pubmed/26908745)
BACKGROUND:
?We describe the impact of early initiation of influenza antiviral treatment among pregnant women hospitalized with laboratory-confirmed influenza during the 2010-2014 influenza seasons.
METHODS: ... VIBOUD C, Simonsen L, Fuentes R, Flores J, et al. Global Mortality Impact of the 1957-1959 Influenza Pandemic. J Infect Dis. 2016 Mar 1;213(5):738-45. doi: 10.10. Abstract
submitted by kickingbird at Mar, 7, 2016 from J Infect Dis. 2016 Mar 1;213(5):738-45. doi: 10.10 (via http://www.ncbi.nlm.nih.gov/pubmed/26908781)
BACKGROUND:
Quantitative estimates of the global burden of the 1957 influenza pandemic are lacking. Here we fill this gap by modeling historical mortality statistics.
METHODS:
We used annual rates ... YU Yang, SI Weiying, YUAN Zhuangchuan, YAN Yan. Isolation and Identification of a Quail-origin H9N2 Subtype of the Influenza Virus and its Biologic Characterization. Chinese Journal of Virology, 2016(01). Abstract
submitted by kickingbird at Feb, 29, 2016 from Chinese Journal of Virology, 2016(01) (via http://www.cnki.net)
Abstract:A quail-origin subtype of the influenza virus was isolated from a human-infecting H7N9 subtype of the avian influenza virus found in a live poultry market and was given the name A/Quail/Hangzhou/1/2013 ... SHA J, Chen X, Ren Y, Chen H, et al. Differences in the epidemiology and virology of mild, severe and fatal human infections with avian influenza A (H7N9) virus. Arch Virol. 2016 Feb 18.. Abstract
submitted by kickingbird at Feb, 21, 2016 from Arch Virol. 2016 Feb 18. (via http://www.ncbi.nlm.nih.gov/pubmed/26887968)
A novel avian influenza A (H7N9) virus caused 5-10 % mild and 30.5 % fatal human infections as of December 10, 2015. In order to investigate the reason for the higher rate of fatal outcome of ... Chen G-W, Kuo S-M, Yang S-L, Gong Y-N, Hsiao M-R,. Genomic Signatures for Avian H7N9 Viruses Adapting to Humans. PLoS ONE 11(2): e0148432.. Abstract
submitted by kickingbird at Feb, 11, 2016 from PLoS ONE 11(2): e0148432. (via http://journals.plos.org/plosone/article?id=10.1371/journal.)
An avian influenza A H7N9 virus emerged in March 2013 and caused a remarkable number of human fatalities. Genome variability in these viruses may provide insights into host adaptability. We scanned over ... MEYER L, Sausset A, Sedano L, Da Costa B, et al. Codon deletions in the influenza A virus PA gene generate temperature-sensitive viruses. J Virol. 2016 Jan 20. pii: JVI.03101-15.. Abstract
submitted by kickingbird at Jan, 24, 2016 from J Virol. 2016 Jan 20. pii: JVI.03101-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26792748)
The influenza virus RNA-dependent RNA polymerase which is composed of three subunits, PB1, PB2, and PA, catalyses genome replication and transcription within the cell nucleus. The PA linker (residues 197-256) ... JAIRAK W, Boonyapisitsopa S, Chaiyawong S, Nonthab. Genetic characterization of influenza A (H7N6) virus isolated from a live-bird market in Thailand. Arch Virol. 2016 Jan 21.. Abstract
submitted by kickingbird at Jan, 24, 2016 from Arch Virol. 2016 Jan 21. (via http://www.ncbi.nlm.nih.gov/pubmed/26795160)
A one-year influenza A virus (IAV) monitoring program was conducted in a live-bird market (LBM) in Thailand. Using one-step real-time RT-PCR (rRT-PCR), 2.39 % of live birds were found to be IAV positive. ... WANG J, Wu M, Hong W, Fan X, et al. Infectivity and Transmissibility of Avian H9N2 Influenza Viruses in Pigs. J Virol. 2016 Jan 13. pii: JVI.02605-15.. Abstract
submitted by kickingbird at Jan, 17, 2016 from J Virol. 2016 Jan 13. pii: JVI.02605-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26764002)
The H9N2 influenza viruses that are enzootic in terrestrial poultry in China pose a persistent pandemic threat to humans. To investigate whether the continuous circulation and adaptation of these viruses ... CHEN CJ, Ermler ME, Tan GS, Krammer F, et al. Influenza A viruses expressing intra- or inter-group chimeric hemagglutinins. J Virol. 2016 Jan 13. pii: JVI.03060-15. Abstract
submitted by kickingbird at Jan, 17, 2016 from J Virol. 2016 Jan 13. pii: JVI.03060-15 (via http://www.ncbi.nlm.nih.gov/pubmed/26764009)
A panel of influenza A viruses expressing chimeric hemagglutinins (cHA) with intragroup or intergroup head/stalk combinations was generated. Viruses were characterized for growth kinetics and preservation ... GAGLANI M, Pruszynski J, Murthy K, Clipper L, et a. Influenza Vaccine Effectiveness Against 2009 Pandemic Influenza A(H1N1) Virus Differed by Vaccine Type During 2013-2014 in the United States. J Infect Dis. 2016 Jan 6. pii: jiv577. Abstract
submitted by kickingbird at Jan, 17, 2016 from J Infect Dis. 2016 Jan 6. pii: jiv577 (via http://www.ncbi.nlm.nih.gov/pubmed/26743842)
BACKGROUND:
?The predominant strain during the 2013-2014 influenza season was 2009 pandemic influenza A(H1N1) virus (A[H1N1]pdm09). This vaccine-component has remained unchanged from 2009.
METHODS: ... 5150 items, 20/Page, Page[167/258][|<<] [|<] [161] [162] [163] [164] [165] [166] [167] [168] [169] [170] [>|] [>>|] |
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