Xue, Ruixue, Ma, Huiling, Jiang, Zixin, Xing, Linl. Diversity of the H9N2 Avian Influenza Virus in Shandong Province, China. Transboundary and Emerging Diseases, 2025, 1432483. Abstract
submitted by kickingbird at Jan, 17, 2025 from Transboundary and Emerging Diseases, 2025, 1432483 (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/1432483)
H9N2 avian influenza virus (AIV) is one of the main pathogens causing respiratory disease in chicken; however, differentiating this virus from infectious bronchitis virus (IBV) and newcastle disease virus ... Duong MH, Phan TNU, Nguyen TH, Ho NHN, Nguyen TN,. Human Infection with Avian Influenza A(H9N2) Virus, Vietnam, April 2024. Emerg Infect Dis. Feb 2025. Abstract
submitted by kickingbird at Jan, 17, 2025 from Emerg Infect Dis. Feb 2025 (via https://wwwnc.cdc.gov/eid/article/31/2/24-1146_article)
In April 2024, Vietnam confirmed its first human case of influenza A(H9N2) in a 37-year-old man, marking a critical point in regional infectious disease monitoring and response. This case underscores the ... Zhang C, Hou J, Li Z, Shen Q, Bai H, Chen L, Shen. PROTAR Vaccine 2.0 generates influenza vaccines by degrading multiple viral proteins. Nat Chem Biol. 2025 Jan 15. Abstract
submitted by kickingbird at Jan, 17, 2025 from Nat Chem Biol. 2025 Jan 15 (via https://www.nature.com/articles/s41589-024-01813-z)
Manipulating viral protein stability using the cellular ubiquitin-proteasome system (UPS) represents a promising approach for developing live-attenuated vaccines. The first-generation proteolysis-targeting ... Shen J, Li J, Shen Q, Hou J, Zhang C, Bai H, Ai X,. Proteolysis-targeting influenza vaccine strains induce broad-spectrum immunity and in vivo protection. Nat Microbiol. 2025 Jan 15. Abstract
submitted by kickingbird at Jan, 17, 2025 from Nat Microbiol. 2025 Jan 15 (via https://www.nature.com/articles/s41564-024-01908-2)
Generating effective live vaccines from intact viruses remains challenging owing to considerations of safety and immunogenicity. Approaches that can be applied in a systematic manner are needed. Here we ... Ma W, Ren C, Shi L, Meng B, Feng Y, Zhang Y. Isoleucine at position 137 of Hemagglutinin acts as a Mammalian adaptation marker of H9N2 Avian influenza virus. Emerg Microbes Infect. 2025 Jan 16:2455597. Abstract
submitted by kickingbird at Jan, 17, 2025 from Emerg Microbes Infect. 2025 Jan 16:2455597 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
The H9N2 subtype of avian influenza virus (AIV) is widely distributed among poultry and wild birds and is also a threat to humans. During AIV active surveillance in Liaoning province from 2015 to 2016, ... Goel V, Ding J, Hatuwal B, Giri E, Deliberto TJ, L. Ecological Drivers of Evolution of Swine Influenza in the United States: A Review. Emerg Microbes Infect. 2025 Jan 16:2455598. Abstract
submitted by kickingbird at Jan, 17, 2025 from Emerg Microbes Infect. 2025 Jan 16:2455598 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Influenza A viruses (IAVs) pose a major public health threat due to their wide host range and pandemic potential. Pigs have been proposed as "mixing vessels" for avian, swine, and human IAVs, significantly ... Gert Zimmer, etc.,al. [preprint]Immunization with a novel RNA replicon vaccine confers long-lasting protection against H5N1 avian influenza virus in 24 bird species. ttps://doi.org/10.1101/2025.01.15.633174. Abstract
submitted by kickingbird at Jan, 16, 2025 from ttps://doi.org/10.1101/2025.01.15.633174 (via https://www.biorxiv.org/content/10.1101/2025.01.15.633174v1)
Highly pathogenic avian influenza viruses (HPAIV) of subtype H5N1 (clade 2.3.4.4b) have spread worldwide and caused the death of hundreds of millions of wild birds and domestic poultry. Moreover, spill ... Bia P, Losardo M, Manna A, Brusaferro S, Privitera. Selected microwave irradiation effectively inactivates airborne avian influenza A(H5N1) virus. Sci Rep. 2025 Jan 15;15(1):2021. Abstract
submitted by kickingbird at Jan, 16, 2025 from Sci Rep. 2025 Jan 15;15(1):2021 (via https://www.nature.com/articles/s41598-025-85376-6)
The highly pathogenic avian influenza A(H5N1) virus threatens animal and human health globally. Innovative strategies are crucial for mitigating risks associated with airborne transmission and preventing ... Jonathan D. Baghdadi, Deborah Grady, Daniel J. Mor. The Limited Role for Antiviral Therapy in Influenza. JAMA Intern Med. Abstract
submitted by kickingbird at Jan, 16, 2025 from JAMA Intern Med (via https://jamanetwork.com/journals/jamainternalmedicine/articl)
Influenza is associated with substantial morbidity and mortality. Given this, antiviral therapy is commonly prescribed in an effort to prevent these outcomes. We therefore found it surprising that antivirals ... Rosenke, K., Giffin, A., Kaiser, F. et al. Pathogenesis of bovine H5N1 clade 2.3.4.4b infection in Macaques. Nature (2025). Abstract
submitted by kickingbird at Jan, 16, 2025 from Nature (2025) (via https://www.nature.com/articles/s41586-025-08609-8)
Since early 2022 highly pathogenic avian influenza (HPAI) H5N1 virus infections have been reported in wild aquatic birds and poultry throughout the United States (US) with spillover into several mammalian ... Victoria Meliopoulos, etc.,al. [preprint]Susceptibility of bovine respiratory and mammary epithelial cells to avian and mammalian derived clade 2.3.4.4b H5N1 highly pathogenic avian influenza viruses. https://doi.org/10.1101/2025.01.09.632235. Abstract
submitted by kickingbird at Jan, 15, 2025 from https://doi.org/10.1101/2025.01.09.632235 (via https://www.biorxiv.org/content/10.1101/2025.01.09.632235v1)
Zoonotic transmission of avian influenza viruses into mammals is relatively rare due to anatomical differences in the respiratory tract between species. Recently, clade 2.3.4.4b highly pathogenic H5N1 ... LI Shan, DONG Hui, YAO Xue, et al. Genetic Diversity of H10N3 Avian Influenza Virus Isolated from Anhui Province, China. Chin J Virol, 2024, 40(05): 1022-1032. Abstract
submitted by kickingbird at Jan, 15, 2025 from Chin J Virol, 2024, 40(05): 1022-1032
In April 2021，the first human case of infection by the H10N3 subtype avian influenza virus (AIV)was identified in Jiangsu，China. The genetic diversity and molecular characterizations of H10N3 subtype AIV ... WANG Shenjiao, QI Xian, YU Huiyan, DENG Fei, HUANG. Molecular origion of human infection with a novel avian influenza A H10N3 virus in China, 2021. Microbiology China, 2023, 50(3): 1231-1244.. Abstract
submitted by kickingbird at Jan, 15, 2025 from Microbiology China, 2023, 50(3): 1231-1244. (via http://journals.im.ac.cn/wswxtbcn)
[Background] Since the human infection with avian influenza that occurred in Hong Kong in 1997, avian influenza virus has become a major threat to human health and public health. [Objective] To perform ... Hawman, D.W., Tipih, T., Hodge, E. et al. Clade 2.3.4.4b but not historical clade 1 HA replicating RNA vaccine protects against bovine H5N1 challenge in mice. Nat Commun 16, 655 (2025). Abstract
submitted by kickingbird at Jan, 15, 2025 from Nat Commun 16, 655 (2025) (via https://link.springer.com/article/10.1038/s41467-024-55546-7)
The ongoing circulation of influenza A H5N1 in the United States has raised concerns of a pandemic caused by highly pathogenic avian influenza. Although the United States has stockpiled and is prepared ... Zou, J., Jiang, M., Xiao, R. et al. GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding. Nat Commun 16, 670 (2025). Abstract
submitted by kickingbird at Jan, 15, 2025 from Nat Commun 16, 670 (2025) (via https://link.springer.com/article/10.1038/s41467-025-55903-0)
The Eurasian avian-like (EA) H1N1 swine influenza virus (SIV) possesses the capacity to instigate the next influenza pandemic, owing to its heightened affinity for the human-type α-2,6 sialic acid (SA) ... Zhuanli Wu, Chengcheng Zhao, etc.,al. A Susceptible Cell-Selective Delivery (SCSD) of mRNA-Encoded Cas13d Against Influenza Infection. Advanced Science (2025). Abstract
submitted by kickingbird at Jan, 15, 2025 from Advanced Science (2025) (via https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.20)
To bolster the capacity for managing potential infectious diseases in the future, it is critical to develop specific antiviral drugs that can be rapidly designed and delivered precisely. Herein, a CRISPR/Cas13d ... Zhao C, Zhang X, Wang H, Qiang H, Liu S, Zhang C,. Proteomic Analysis of Differentially Expressed Proteins in A549 Cells Infected with H9N2 Avian Influenza Virus. International Journal of Molecular Sciences. 2025;. Abstract
submitted by kickingbird at Jan, 15, 2025 from International Journal of Molecular Sciences. 2025; (via https://www.mdpi.com/1422-0067/26/2/657)
Influenza A viruses (IAVs) are highly contagious pathogens that cause zoonotic disease with limited availability of antiviral therapies, presenting ongoing challenges to both public health and the livestock ... Liu S, Lin M, Zhou X. T4 Phage Displaying Dual Antigen Clusters Against H3N2 Influenza Virus Infection. Vaccines. 2025; 13(1):70. Abstract
submitted by kickingbird at Jan, 15, 2025 from Vaccines. 2025; 13(1):70 (via https://www.mdpi.com/2076-393X/13/1/70)
Background: The current H3N2 influenza subunit vaccine exhibits weak immunogenicity, which limits its effectiveness in preventing and controlling influenza virus infections. Methods: In this study, we ... Zhimin Wan, etc.,al. Identification of key antigenic sites in hemagglutinin of H10N3 avian influenza virus. Poultry Science (2024). Abstract
submitted by kickingbird at Jan, 15, 2025 from Poultry Science (2024) (via https://www.sciencedirect.com/science/article/pii/S003257912)
The H10 avian influenza viruses (AIV) have been detected in both birds and mammals. Recently, the cases of human infection with H10N8 and H10N3 in China pose high risk to public health. However, the antigenic ... Martins RP, Marc D, Germon P, Trapp S, Caballero-P. Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines. NPJ Vaccines. 2025 Jan 14;10(1):8. Abstract
submitted by kickingbird at Jan, 14, 2025 from NPJ Vaccines. 2025 Jan 14;10(1):8 (via https://www.nature.com/articles/s41541-025-01063-7)
Influenza, a major "One Health" threat, has gained heightened attention following recent reports of highly pathogenic avian influenza in dairy cattle and cow-to-human transmission in the USA. This review ... 9876 items, 20/Page, Page[80/494][|<<] [|<] [71] [72] [73] [74] [75] [76] [77] [78] [79] [80] [>|] [>>|] |
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