Beate M. Crossley, etc.,al. In laboratory inactivation of H5N1 in raw whole milk through milk acidification: results from a pilot study. Journal of Dairy Science. Abstract
submitted by kickingbird at Jan, 30, 2025 from Journal of Dairy Science (via https://www.sciencedirect.com/science/article/pii/S002203022)
Avian Influenza virus H5N1 2.3.4.4.b has recently been detected in cattle, with milk from infected animals reported to contain a high viral load, serving as a potential source for shedding and dissemination ... Nicholas C. Morano, etc.,al. Structure of a zoonotic H5N1 hemagglutinin reveals a receptor-binding site occupied by an auto-glycan. Structure, January 2025. Abstract
submitted by kickingbird at Jan, 30, 2025 from Structure, January 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S09692)
Highly pathogenic avian influenza has spilled into many mammals, most notably cows and poultry, with several dozen human breakthrough infections. Zoonotic crossovers, with hemagglutinins mutated to enhance ... Huarui Duan, etc.,al. Computational design and improvement of a broad influenza virus HA stem targeting antibody. Structure, January 2025. Abstract
submitted by kickingbird at Jan, 30, 2025 from Structure, January 2025 (via https://www.sciencedirect.com/science/article/abs/pii/S09692)
Broadly neutralizing antibodies (nAbs) are vital therapeutic tools to counteract both pandemic and seasonal influenza threats. Traditional strategies for optimizing nAbs generally rely on labor-intensive, ... Nishiyama A, Nogimori T, Masuta Y, Matsuura T, Kas. Cross-Reactive Fc-Mediated Antibody Responses to Influenza HA Stem Region in Human Sera Following Seasonal Vaccination. Vaccines. 2025; 13(2):140. Abstract
submitted by kickingbird at Jan, 30, 2025 from Vaccines. 2025; 13(2):140 (via https://www.mdpi.com/2076-393X/13/2/140)
Background: Current influenza A vaccines primarily induce neutralizing antibodies targeting the variable hemagglutinin (HA) head domain, limiting their effectiveness against diverse or emerging influenza ... Wang Z, Tian C, Zhu J, Wang S, Ao X, He Y, Chen H,. Avian influenza mRNA vaccine encoding hemagglutinin provides complete protection against divergent H5N1 viruses in specific-pathogen-free chickens. J Nanobiotechnology. 2025 Jan 29;23(1):55. Abstract
submitted by kickingbird at Jan, 30, 2025 from J Nanobiotechnology. 2025 Jan 29;23(1):55 (via https://jnanobiotechnology.biomedcentral.com/articles/10.118)
Background: The rapid mutation of avian influenza virus (AIV) poses a significant threat to both the poultry industry and public health. Herein, we have successfully developed an mRNA-LNPs candidate vaccine ... Julia Lechmann, etc.,al. [preprint]The Swiss national program for the surveillance of influenza A viruses in pigs and humans: genetic variability and zoonotic transmissions from 2010-2022. https://doi.org/10.1101/2025.01.28.24319114. Abstract
submitted by kickingbird at Jan, 30, 2025 from https://doi.org/10.1101/2025.01.28.24319114 (via https://www.medrxiv.org/content/10.1101/2025.01.28.24319114v)
Influenza A viruses (IAV) are likely candidates for pandemics. This report summarizes the results of the Swiss national program for surveillance of influenza viruses in pigs and transmissions to humans ... Thomas Rawson, etc.,al. [preprint]A mathematical model of H5N1 influenza transmission in US dairy cattle.. https://doi.org/10.1101/2025.01.28.25321250. Abstract
submitted by kickingbird at Jan, 30, 2025 from https://doi.org/10.1101/2025.01.28.25321250 (via https://www.medrxiv.org/content/10.1101/2025.01.28.25321250v)
We present a stochastic metapopulation transmission model that simulates the spread of H5N1 avian influenza through individual dairy cows in 35,974 dairy herds in the continental United States. Transmission ... Zhang L, Yang Q, Shao Y, Ding S, Guo J, Gao GF, De. Influenza A virus NS2 protein acts on vRNA-resident polymerase to drive the transcription to replication switch. Nucleic Acids Res. 2025 Jan 24;53(3):gkaf027. Abstract
submitted by kickingbird at Jan, 30, 2025 from Nucleic Acids Res. 2025 Jan 24;53(3):gkaf027 (via https://academic.oup.com/nar/article/53/3/gkaf027/7986046)
The heterotrimeric RNA-dependent RNA polymerase (RdRp) of influenza A virus catalyzes viral RNA transcription (vRNA→mRNA) and replication (vRNA→cRNA→vRNA) by adopting different conformations. A switch ... WHO. Influenza at the human-animal interface summary and assessment, 20 January 2025. WHO. Abstract
submitted by kickingbird at Jan, 28, 2025 from WHO (via https://www.who.int/publications/m/item/influenza-at-the-hum)
From 13 December 2024 to 20 January 2025, the detection of influenza A(H5) virus in five humans, influenza A(H9N2) virus in two humans, and influenza A(H10N3) virus in one human were reported officially. ... Jie Hu, Yuting Xu, Min Ma, Chenyao Zhao, Yue Yuan,. Novel Reassortant Avian Influenza A(H9N2) Viruses in Wild Birds in Shanghai, China, 2020–2023. Poultry Science. Abstract
submitted by kickingbird at Jan, 28, 2025 from Poultry Science (via https://www.sciencedirect.com/science/article/pii/S003257912)
The H9N2 subtype of avian influenza virus poses significant challenges to global poultry and human health. During the active surveillance of avian influenza virus in wild birds in Shanghai from 2020 to ... Yan M, Ma T, Shi X, Chen Q, Li L, Xu B, Pan X, Ten. Isolation and Characterization of H1 Subtype Swine Influenza Viruses Recently Circulating in China. Viruses. 2025; 17(2):185. Abstract
submitted by kickingbird at Jan, 28, 2025 from Viruses. 2025; 17(2):185 (via https://www.mdpi.com/1999-4915/17/2/185)
Pigs serve as a mixing vessel for influenza viruses and can independently promote the emergence of pandemic strains in humans. During our surveillance of pig populations from 2021 to 2023 in China, 11 ... Figueroa T, Bessière P, Coggon A, Bouwman KM, van. The Microbiota Contributes to the Control of Highly Pathogenic H5N9 Influenza Virus Replication in Ducks. J Virol. 2020 May 4;94(10):e00289-20. Abstract
submitted by kickingbird at Jan, 28, 2025 from J Virol. 2020 May 4;94(10):e00289-20 (via https://journals.asm.org/doi/10.1128/jvi.00289-20)
Ducks usually show little or no clinical signs following highly pathogenic avian influenza virus infection. In order to analyze whether the microbiota could contribute to the control of influenza virus ... Yuk SS, To EO, Kwon JH, Noh JY, Hong WT, Jeong JH,. Optimization of inactivated H5N9 highly pathogenic avian influenza vaccine and inactivated Salmonella enterica serovar Typhimurium vaccine with antigen dose and prime-boost regimen in domestic ducks. Poult Sci. 2017 Sep 1;96(9):3079-3085. Abstract
submitted by kickingbird at Jan, 28, 2025 from Poult Sci. 2017 Sep 1;96(9):3079-3085 (via https://www.sciencedirect.com/science/article/pii/S003257911)
Owing to the increase in the number of diseases affecting ducks and the demand for food safety by consumers, vaccination has become one of the factors that influence duck meat productivity. The highly ... Briand FX, Schmitz A, Ogor K, Le Prioux A, Guillou. Emerging highly pathogenic H5 avian influenza viruses in France during winter 2015/16: phylogenetic analyses and markers for zoonotic potential. Euro Surveill. 2017 Mar 2;22(9):30473. Abstract
submitted by kickingbird at Jan, 28, 2025 from Euro Surveill. 2017 Mar 2;22(9):30473 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Several new highly pathogenic (HP) H5 avian influenza virus (AIV) have been detected in poultry farms from south-western France since November 2015, among which an HP H5N1. The zoonotic potential and origin ... Yu Y, Wang X, Jin T, Wang H, Si W, Yang H, Wu J, Y. Newly Emergent Highly Pathogenic H5N9 Subtype Avian Influenza A Virus. J Virol. 2015 Sep;89(17):8806-15. Abstract
submitted by kickingbird at Jan, 28, 2025 from J Virol. 2015 Sep;89(17):8806-15 (via https://journals.asm.org/doi/10.1128/jvi.00653-15)
The novel H7N9 avian influenza virus (AIV) was demonstrated to cause severe human respiratory infections in China. Here, we examined poultry specimens from live bird markets linked to human H7N9 infection ... El-Shesheny R, Gomaa M, Sayes ME, Kamel MN, Taweel. Emergence of a novel reassortant highly pathogenic avian influenza clade 2.3.4.4b A(H5N2) Virus, 2024. Emerg Microbes Infect. 2025 Jan 27:2455601. Abstract
submitted by kickingbird at Jan, 28, 2025 from Emerg Microbes Infect. 2025 Jan 27:2455601 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Reassortant highly pathogenic avian influenza A(H5N2) clade 2.3.4.4.b viruses were detected from ducks and environmental samples in Egypt, June 2024. Genomic and phylogenetic analyses revealed a novel ... Postel A, Gremmel N, Lydersen C, Kovacs KM, Schick. Highly pathogenic avian influenza virus (H5N5) detected in an Atlantic walrus (Odobenus rosmarus rosmarus) in the Svalbard Archipelago, Norway, 2023. Emerg Microbes Infect. 2025 Jan 27:2456146. Abstract
submitted by kickingbird at Jan, 28, 2025 from Emerg Microbes Infect. 2025 Jan 27:2456146 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
We present the first documented case of highly pathogenic avian influenza virus (HPAIV) subtype H5N5 in an Atlantic walrus (Odobenus rosmarus rosmarus). The animal was found dead in Svalbard, Norway, in ... Smith S, Rayner JO, Kim JH. Fluorofurimazine, a novel NanoLuc substrate, enhances real-time tracking of influenza A virus infection without altering pathogenicity in mice. Microbiol Spectr. 2025 Jan 27:e0268924. Abstract
submitted by kickingbird at Jan, 28, 2025 from Microbiol Spectr. 2025 Jan 27:e0268924 (via https://journals.asm.org/doi/10.1128/spectrum.02689-24)
Bioluminescence imaging (BLI) using engineered bioluminescent viruses has emerged as a powerful tool for real-time, noninvasive monitoring of viral replication in living animals. While traditional luciferase-based ... Zhang Y, Wu J, Lin Q, Ou J, Qi X, Zheng Y, Li F, W. Infection Tracing and Virus Genomic Analysis of Two Cases of Human Infection with Avian Influenza A(H5N6) - Fujian Province, China, April-May 2024. China CDC Wkly. 2025 Jan 17;7(3):107-112. Abstract
submitted by kickingbird at Jan, 28, 2025 from China CDC Wkly. 2025 Jan 17;7(3):107-112 (via https://weekly.chinacdc.cn/en/article/doi/10.46234/ccdcw2024)
What is known about this topic?: Global human cases of zoonotic influenza A(H5N6) have increased significantly in recent years, primarily due to widespread circulation of clade 2.3.4.4b virus since 2020. ... Gu J, Yan Y, Zeng Z, Liu D, Hu J, Hu S, Wang X, Gu. Hemagglutinin with a polybasic cleavage site confers high virulence on H7N9 avian influenza viruses. Poult Sci. 2025 Jan 18;104(2):104832. Abstract
submitted by kickingbird at Jan, 27, 2025 from Poult Sci. 2025 Jan 18;104(2):104832 (via https://www.sciencedirect.com/science/article/pii/S003257912)
H7N9 avian influenza virus (AIV) first emerged in February 2013 in China, and early isolates were all low pathogenic (LP). After circulation for a few years in live poultry markets of China, LP H7N9 AIVs ... 9876 items, 20/Page, Page[78/494][|<<] [|<] [71] [72] [73] [74] [75] [76] [77] [78] [79] [80] [>|] [>>|] |
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