Pascua PNQ, Chesnokov A, Nguyen HT, Di H, Cruz JDL. Antiviral Susceptibility of Influenza A(H5N1) Clade 2.3.2.1c and 2.3.4.4b Viruses from Humans, 2023~2024. Emerg Infect Dis. 2025 Apr. Abstract
submitted by kickingbird at Mar, 9, 2025 from Emerg Infect Dis. 2025 Apr (via https://wwwnc.cdc.gov/eid/article/31/4/24-1820_article)
During 2023~2024, highly pathogenic avian influenza A(H5N1) viruses from clade 2.3.2.1c caused human infections in Cambodia and from clade 2.3.4.4b caused human infections in the Americas. We assessed ... Levine MZ, Liu F, Bagdasarian N, Haliday C, Jeffer. Neutralizing Antibody Response to Influenza A(H5N1) Virus in Dairy Farm Workers, Michigan, USA. Emerg Infect Dis. 2025 Apr. Abstract
submitted by kickingbird at Mar, 9, 2025 from Emerg Infect Dis. 2025 Apr (via https://wwwnc.cdc.gov/eid/article/31/4/25-0007_article)
Since March 2024, highly pathogenic avian influenza A(H5N1) viruses have caused outbreaks in dairy cattle and poultry in the United States, and they continue to spill over into humans. However, data on ... Ebell MH, Rahmatullah I, Hulme C, Buhr M, Kotnik J. Accuracy of individual signs and symptoms and case definitions for the diagnosis of influenza in different age groups: a systematic review with meta-analysis. BMJ Open. 2025 Mar 3;15(3):e067574. Abstract
submitted by kickingbird at Mar, 8, 2025 from BMJ Open. 2025 Mar 3;15(3):e067574 (via https://pmc.ncbi.nlm.nih.gov/articles/PMC11877276/)
Objective: The objective of this study is to perform a comprehensive systematic review and meta-analysis of the accuracy of signs, symptoms and case definitions for the diagnosis of influenza.Design: Systematic ... Xiao N, Oong XY, Chen Y, Li C, Chung HC, Wang P, Y. Reverse genetics-derived cattle H5N1 virus from Clade 2.3.4.4b shows enhanced systemic infectivity and pathogenicity than an older Clade 1 H5N1 virus in BALB/c mice. Emerg Microbes Infect. 2025 Mar 4:2475836. Abstract
submitted by kickingbird at Mar, 8, 2025 from Emerg Microbes Infect. 2025 Mar 4:2475836 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
The newly emerged avian influenza A H5N1 Clade 2.3.4.4b can infect dairy cows and shed live virus in their milk. Sporadic cattle-to-human infections have been reported, highlighting the urgent need to ... Branda F, Mohapatra RK, Tuglo LS, Ciccozzi M, Scar. Real-time epidemiological surveillance data: tracking the occurrences of avian influenza outbreaks around the world. BMC Res Notes. 2025 Mar 4;18(1):95. Abstract
submitted by kickingbird at Mar, 8, 2025 from BMC Res Notes. 2025 Mar 4;18(1):95 (via https://bmcresnotes.biomedcentral.com/articles/10.1186/s1310)
Objectives: This study aims to provide real-time surveillance of epidemiological outbreaks of avian influenza in humans and mammals. The primary objective is to understand and track the dynamics of outbreaks ... Zhong S, Thompson MG, Cowling BJ. The Potential for Twice-Annual Influenza Vaccination to Reduce Disease Burden. Influenza Other Respir Viruses. 2025 Mar;19(3):e70. Abstract
submitted by kickingbird at Mar, 8, 2025 from Influenza Other Respir Viruses. 2025 Mar;19(3):e70 (via https://pubmed.ncbi.nlm.nih.gov/40045876/)
Background: Influenza vaccination is recommended annually based on the evolving nature of influenza viruses and the waning of vaccine-induced immunity. The timing of vaccination is usually before the winter ... Lu X, Li W, Li P, Li Y, Gou Y, Wang T, Liu Z, Wu Y. Selection and identification of an ssDNA aptamer against influenza B virus hemagglutinin protein. Virol J. 2025 Mar 7;22(1):64. Abstract
submitted by kickingbird at Mar, 8, 2025 from Virol J. 2025 Mar 7;22(1):64 (via https://virologyj.biomedcentral.com/articles/10.1186/s12985-)
Background: The influenza virus causes infectious respiratory disease with high morbidity and mortality worldwide. Influenza B typically goes unnoticed owing to its mild clinical symptoms and limitations. ... Jing Yang, etc.,al. A human-infecting H10N5 avian influenza virus: clinical features, virus reassortment, receptor-binding affinity, and possible transmission routes. Journal of Infection Available online 4 March 2025. Abstract
submitted by kickingbird at Mar, 6, 2025 from Journal of Infection Available online 4 March 2025 (via https://www.sciencedirect.com/science/article/pii/S016344532)
BackgroundIn late 2023, the first human case caused by an H10N5 avian influenza virus (AIV) was diagnosed in China. H10Ny AIVs have been identified in various poultry and wild birds in Eurasia, the Americas, ... Taeyong Kwon, etc.,al. [preprint]Pathogenicity and transmissibility of bovine-derived HPAI H5N1 B3.13 virus in pigs. https://doi.org/10.1101/2025.03.04.641414. Abstract
submitted by kickingbird at Mar, 6, 2025 from https://doi.org/10.1101/2025.03.04.641414 (via https://www.biorxiv.org/content/10.1101/2025.03.04.641414v1)
Since the first emergence of highly pathogenic avian influenza (HPAI) H5N1 viruses in dairy cattle, the virus has continued to spread, reaching at least 16 states and at least 950 dairy herds in the United ... Cassandra J Field, etc.,al. [preprint]Defining the transmissible dose 50%, the donor inoculation dose that results in airborne transmission to 50% of contacts, for two pandemic influenza viruses in ferrets. https://doi.org/10.1101/2025.03.04.641289. Abstract
submitted by kickingbird at Mar, 6, 2025 from https://doi.org/10.1101/2025.03.04.641289 (via https://www.biorxiv.org/content/10.1101/2025.03.04.641289v1)
Ferrets are widely used to model airborne transmission of influenza viruses in humans. Airborne transmission is evaluated by infecting donor ferrets with a high virus dose (106 infectious units) and monitoring ... Neda Nasheri, etc.,al. [preprint]Examining the Survival of A(H5N1) Influenza Virus in Thermised Whole Cow Milk. https://doi.org/10.1101/2025.03.05.641644. Abstract
submitted by kickingbird at Mar, 6, 2025 from https://doi.org/10.1101/2025.03.05.641644 (via https://www.biorxiv.org/content/10.1101/2025.03.05.641644v1)
The recent spillover events of highly pathogenic avian influenza (HPAI) A(H5N1) clade 2.3.4.4b to dairy cattle, and high viral shedding in the milk from infected animals, has created concern that milk ... Pardo-Roa, C., Nelson, M.I., Ariyama, N. et al. Cross-species and mammal-to-mammal transmission of clade 2.3.4.4b highly pathogenic avian influenza A/H5N1 with PB2 adaptations. Nat Commun 16, 2232 (2025). Abstract
submitted by kickingbird at Mar, 6, 2025 from Nat Commun 16, 2232 (2025) (via https://www.nature.com/articles/s41467-025-57338-z)
Highly pathogenic H5N1 avian influenza viruses (HPAIV) belonging to lineage 2.3.4.4b emerged in Chile in December 2022, leading to mass mortality events in wild birds, poultry, and marine mammals and one ... Qianqian Li, etc.,al. [preprint]Dominant substitutions underlying the antigenic evolution of H5 influenza virus. https://doi.org/10.21203/rs.3.rs-6040842/v1. Abstract
submitted by kickingbird at Mar, 5, 2025 from https://doi.org/10.21203/rs.3.rs-6040842/v1 (via https://www.researchsquare.com/article/rs-6040842/v1)
Highly pathogenic avian influenza (HPAI) H5 viruses have recently been documented in mammals including humans, posing a major threat to global public health. To prevent a potential H5 pandemic, it is critical ... Li S, Chu L, Zhang Y, Yu Y and Wang G. Genetic characterization of an H3N2 canine influenza virus strain in China in 2023-acquisition of novel human-like amino acid substitutions. Front. Vet. Sci. 12:1552115. Abstract
submitted by kickingbird at Mar, 4, 2025 from Front. Vet. Sci. 12:1552115 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Around 2005, influenza A virus (IAV) once again crossed species barriers and established a stable lineage within canine populations. Currently, avian-origin H3N2 canine influenza virus (CIV) is the only ... WPRO. WHO: Avian Influenza Weekly Update # 987: 28 February 2025. WHO/WPRO. Abstract
submitted by kickingbird at Mar, 3, 2025 from WHO/WPRO (via https://cdn.who.int/media/docs/default-source/wpro---documen)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ... Mahmoud Bayoumi, etc.,al. [preprint]Identification of Amino Acid Residues Responsible for Differential Replication and Pathogenicity of Avian Influenza Virus H5N1 Isolated from Human and Cattle in Texas, US. https://doi.org/10.1101/2025.03.01.640810. Abstract
submitted by kickingbird at Mar, 3, 2025 from https://doi.org/10.1101/2025.03.01.640810 (via https://www.biorxiv.org/content/10.1101/2025.03.01.640810v1)
Highly pathogenic avian influenza viruses (HPAIV) pose a serious public health concern. In March 2024, a first-time outbreak of HPAIV H5N1 in dairy cattle herds was reported in the United States (US). ... Hoang-Hai Nguyen, etc.,al. [preprint]WaveSeekerNet: Accurate Prediction of Influenza A Virus Subtypes and Host Source Using Attention-Based Deep Learning. https://doi.org/10.1101/2025.02.25.639900. Abstract
submitted by kickingbird at Mar, 2, 2025 from https://doi.org/10.1101/2025.02.25.639900 (via https://www.biorxiv.org/content/10.1101/2025.02.25.639900v1)
Background Influenza A virus (IAV) poses a significant threat to animal health globally, with its ability to overcome species barriers and cause pandemics. Rapid and accurate prediction of IAV subtypes ... Hugo Castelan-Sanchez, Art Poon. [preprint]Phylogenetic discordance cannot identify genomic reassortment events: a case study with the avian influenza virus H5Nx. https://doi.org/10.1101/2025.02.24.639875. Abstract
submitted by kickingbird at Mar, 2, 2025 from https://doi.org/10.1101/2025.02.24.639875 (via https://www.biorxiv.org/content/10.1101/2025.02.24.639875v1)
Recombination plays a central role in the evolution of the RNA virus genome, as it allows the exchange of genetic material between different viral lineages. Reassortment is a form of recombination specific ... Kj?r, L.J., Kirkeby, C.T., Boklund, A.E. et al. Prediction models show differences in highly pathogenic avian influenza outbreaks in Japan and South Korea compared to Europe. Sci Rep 15, 6783 (2025). Abstract
submitted by kickingbird at Mar, 2, 2025 from Sci Rep 15, 6783 (2025) (via https://link.springer.com/article/10.1038/s41598-025-91384-3)
Avian influenza poses substantial risks to animal welfare and public health. The recent surge in highly pathogenic avian influenza (HPAI) outbreaks has led to extensive poultry culling, highlighting the ... Murray J, Nogales A, Martinez-Sobrido L, Martin DE. Evaluating Probenecid or Oseltamivir Inhibition of Influenza A Virus Replication Through Plaque Assay or Fluorescent Focus Assay Using Non-Structural Protein 1–H1N1 Venus Reporter Virus. Viruses. 2025; 17(3):335. Abstract
submitted by kickingbird at Mar, 2, 2025 from Viruses. 2025; 17(3):335 (via https://www.mdpi.com/1999-4915/17/3/335)
It is essential to understand the molecular mechanisms of influenza antiviral therapeutics to evaluate their efficacy. Virus plaque assays are commonly used to assess the antiviral effects of drugs on ... 9876 items, 20/Page, Page[71/494][|<<] [|<] [71] [72] [73] [74] [75] [76] [77] [78] [79] [80] [>|] [>>|] |
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