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2025-12-5 22:05:05
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Jallow MM, Diagne MM, Ndione MHD, Barry MA, Ndiaye. Genetic and Molecular Characterization of Avian Influenza A(H9N2) Viruses from Live Bird Markets (LBM) in Senegal. Viruses. 2025; 17(1):73.  Abstract  
submitted by kickingbird at Jan, 9, 2025 from Viruses. 2025; 17(1):73 (via https://www.mdpi.com/1999-4915/17/1/73)
Despite extensive experience with influenza surveillance in humans in Senegal, there is limited knowledge about the actual situation and genetic diversity of avian influenza viruses (AIVs) circulating ...

Escuyer KL, Gowie DL, St. George K. Influenza Virus Surveillance from the 1918 Influenza Pandemic to the 2020 Coronavirus Pandemic in New York State, USA. Viruses. 2024; 16(12):1952.  Abstract  
submitted by kickingbird at Jan, 9, 2025 from Viruses. 2024; 16(12):1952 (via https://www.mdpi.com/1999-4915/16/12/1952)
A historical perspective of more than one hundred years of influenza surveillance in New York State demonstrates the progression from anecdotes and case counts to next-generation sequencing and electronic ...

Rowe T, Fletcher A, Lange M, Hatta Y, Jasso G, Wen. Delay of innate immune responses following influenza B virus infection affects the development of a robust antibody response in ferrets. mBio. 2025 Jan 8:e0236124.  Abstract  
submitted by kickingbird at Jan, 9, 2025 from mBio. 2025 Jan 8:e0236124 (via https://journals.asm.org/doi/10.1128/mbio.02361-24)
Due to its natural influenza susceptibility, clinical signs, transmission, and similar sialic acid residue distribution, the ferret is the primary animal model for human influenza research. Antibodies ...

Wang, Y., Wang, H., Zhang, Y. et al. Single-dose suraxavir marboxil for acute uncomplicated influenza in adults and adolescents: a multicenter, randomized, double-blind, placebo-controlled phase 3 trial. Nat Med (2025).  Abstract  
submitted by kickingbird at Jan, 9, 2025 from Nat Med (2025) (via https://www.nature.com/articles/s41591-024-03419-3)
Suraxavir marboxil (GP681) is an antiviral drug inhibiting the polymerase acidic protein (PA) of RNA polymerase, of influenza. It has shown therapeutic activity against influenza A and B virus infections ...

Vidhi Dholakia, etc.,al. [preprint]Polymerase mutations underlie adaptation of H5N1 influenza virus to dairy cattle and other mammals. https://doi.org/10.1101/2025.01.06.631435.  Abstract  
submitted by kickingbird at Jan, 9, 2025 from https://doi.org/10.1101/2025.01.06.631435 (via https://www.biorxiv.org/content/10.1101/2025.01.06.631435v1)
In early 2024, an unprecedented outbreak of H5N1 high pathogenicity avian influenza was detected in dairy cattle in the USA. The epidemic remains uncontrolled, with spillbacks into poultry, wild birds ...

Manlin He, etc.,al. The H5N6 Virus Containing Internal Genes From H9N2 Exhibits Enhanced Pathogenicity and Transmissibility. Transboundary and Emerging Diseases.  Abstract  
submitted by kickingbird at Jan, 8, 2025 from Transboundary and Emerging Diseases (via https://onlinelibrary.wiley.com/doi/10.1155/tbed/6252849)
The H5N6 avian influenza virus (AIV) is constantly undergoing recombination and evolution with other subtypes of AIV, resulting in various types of recombinant H5N6 viruses. However, the risk to human ...

Ashraf MA, Raza MA, Imran A, Amjad MN. Next-generation vaccines for influenza B virus: advancements and challenges. Arch Virol. 2025 Jan 6;170(2):25.  Abstract  
submitted by kickingbird at Jan, 8, 2025 from Arch Virol. 2025 Jan 6;170(2):25 (via https://link.springer.com/article/10.1007/s00705-024-06210-4)
To battle seasonal outbreaks of influenza B virus infection, which continue to pose a major threat to world health, new and improved vaccines are urgently needed. In this article, we discuss the current ...

Arvia R, Rocca A, Casciato B, Stincarelli MA, Gian. High-resolution melting analysis for detection of nucleotide mutation markers in the polymerase-acidic (PA) gene of influenza virus that are associated with baloxavir marboxil resistance. Arch Virol. 2025 Jan 6;170(2):29.  Abstract  
submitted by kickingbird at Jan, 8, 2025 from Arch Virol. 2025 Jan 6;170(2):29 (via https://link.springer.com/article/10.1007/s00705-024-06214-0)
The I38T substitution in the influenza virus polymerase-acidic (PA) subunit is a resistance marker of concern for treatment with the antiviral baloxavir marboxil (BXM). Thus, monitoring PA/I38T mutations ...

Song J-H, Son S-E, Kim H-W, An S-H, Lee C-Y, Kwon. A Model H5N2 Vaccine Strain for Dual Protection Against H5N1 and H9N2 Avian Influenza Viruses. Vaccines. 2025; 13(1):22.  Abstract  
submitted by kickingbird at Jan, 7, 2025 from Vaccines. 2025; 13(1):22 (via https://www.mdpi.com/2076-393X/13/1/22)
Background/Objective: Highly pathogenic (HP) H5Nx and low-pathogenicity (LP) H9N2 avian influenza viruses (AIVs) pose global threats to the poultry industry and public health, highlighting the critical ...

Tremlett, C. J., Cleasby, I. R., Bolton, M., & Wil. Declines in UK breeding populations of seabird species of conservation concern following the outbreak of high pathogenicity avian influenza (HPAI) in 2021–2022. Bird Study, 1–18.  Abstract  
submitted by kickingbird at Jan, 6, 2025 from Bird Study, 1–18 (via https://www.tandfonline.com/doi/full/10.1080/00063657.2024.2)
CapsuleUK breeding populations of Great Skua Stercorarius skua, Northern Gannet Morus bassanus, Sandwich Tern Thalasseus sandvicensis and Common Tern Sterna hirundo decreased substantially between the ...

Przymencki, M., Beuch, S., Indykiewicz, P., Litwin. Mortality among scarce breeding gulls and terns during a highly pathogenic avian influenza (HPAI) H5N1 virus outbreak in Poland during 2023. Bird Study, 1–10.  Abstract  
submitted by kickingbird at Jan, 6, 2025 from Bird Study, 1–10 (via https://www.tandfonline.com/doi/full/10.1080/00063657.2024.2)
CapsuleDuring spring and summer 2023, the highly pathogenic avian influenza (HPAI) H5N1 virus caused mass mortality among colony-breeding gulls and terns in Poland.AimsTo document the national impact of ...

Altan, E., Avelin, V., Aaltonen, K., Korhonen, E.,. Highly Pathogenic Avian Influenza (HPAI) H5N1 virus in Finland in 2021-2023 – Genetic diversity of the viruses and infection kinetics in human dendritic cells. Emerging Microbes & Infections.  Abstract  
submitted by kickingbird at Jan, 6, 2025 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
Highly pathogenic avian influenza (HPAI) H5N1 is known for its virulence and zoonotic potential, infecting birds and mammals, thus raising public health concerns. Since 2021 its spread among birds has ...

Yuncong Yin, etc.,al. Random forest algorithm reveals novel sites in HA protein that shift receptor binding preference of the H9N2 avian influenza virus. Virologica Sinica.  Abstract  
submitted by kickingbird at Jan, 6, 2025 from Virologica Sinica (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
A switch from avian-type α-2,3 to human-type α-2,6 receptors is an essential element for the initiation of a pandemic from an avian influenza virus. Some H9N2 viruses exhibit a preference for binding to ...

Abigail P Paulos, etc.,al. [preprint]Detection of Hemagglutinin H5 influenza A virus RNA and model of potential inputs in an urban California sewershed. https://doi.org/10.1101/2024.12.31.24319823.  Abstract  
submitted by kickingbird at Jan, 5, 2025 from https://doi.org/10.1101/2024.12.31.24319823 (via https://www.medrxiv.org/content/10.1101/2024.12.31.24319823v)
In 2024, the highly pathogenic avian influenza A H5N1 caused outbreaks in wild birds, poultry, cows, and other mammals in the United States with 61 human cases also reported by the CDC. Detection of influenza ...

Zhao Y, Han L, Sang H, Yang P, Hou Y, Xiao Y. Two genotypes of H3N2 swine influenza viruses identified in pigs from Shandong Province, China. Front Cell Infect Microbiol. 2024 Dec 16;14:151702.  Abstract  
submitted by kickingbird at Jan, 3, 2025 from Front Cell Infect Microbiol. 2024 Dec 16;14:151702 (via https://www.frontiersin.org/journals/cellular-and-infection-)
Swine influenza virus (SIV) is a highly contagious pathogen that poses significant economic challenges to the swine industry and carries zoonotic potential, underscoring the need for vigilant surveillance. ...

Maria Ogrzewalska, etc.,al. [preprint]High Pathogenicity Avian Influenza Virus (HPAIV) H5N1 clade 2.3.4.4b recovered from a kelp gull (Larus dominicanus) in the South Shetland Islands, Antarctica. https://doi.org/10.1101/2024.12.29.630510.  Abstract  
submitted by kickingbird at Jan, 1, 2025 from https://doi.org/10.1101/2024.12.29.630510 (via https://www.biorxiv.org/content/10.1101/2024.12.29.630510v1)
Whole-genome analysis of the earliest-detected High Pathogenicity Avian Influenza Virus (HPAIV) H5N1 clade 2.3.4.4b detected in Hannah Point, Antarctica (January 2024) reveals close relatedness to strains ...

Jasmina M. Luczo, Erica Spackman. Molecular Evolution of the H5 and H7 Highly Pathogenic Avian Influenza Virus Haemagglutinin Cleavage Site Motif. Reviews in Medical Virology Volume 35, Issue 1.  Abstract  
submitted by kickingbird at Jan, 1, 2025 from Reviews in Medical Virology Volume 35, Issue 1 (via https://onlinelibrary.wiley.com/doi/10.1002/rmv.70012)
Avian influenza viruses are ubiquitous in the Anatinae subfamily of aquatic birds and occasionally spill over to poultry. Infection with low pathogenicity avian influenza viruses generally leads to subclinical ...

Kevin S. Kuchinski, etc.,al. Detection of a Reassortant Swine- and Human-Origin H3N2 Influenza A Virus in Farmed Mink in British Columbia, Canada. Zoonoses and Public Health.  Abstract  
submitted by kickingbird at Jan, 1, 2025 from Zoonoses and Public Health (via https://onlinelibrary.wiley.com/doi/10.1111/zph.13205)
IntroductionIn December 2021, influenza A viruses (IAV) were detected in a population of farmed mink in British Columbia, Canada. Circulation of IAVs in farmed mink populations has raised public health ...

Lin-Lei Chen, etc.,al. [preprint]Risk assessment of 2024 cattle H5N1 using age-stratified serosurveillance data. https://doi.org/10.1101/2024.12.23.24319580.  Abstract  
submitted by kickingbird at Jan, 1, 2025 from https://doi.org/10.1101/2024.12.23.24319580 (via https://www.medrxiv.org/content/10.1101/2024.12.23.24319580v)
The highly pathogenic avian influenza virus A(H5N1) clade 2.3.4.4b has caused a human outbreak in North America since March 2024. Here, we conducted a serosurveillance study to determine the risk of A(H5N1) ...

Yujia Yang, etc.,al. Rapid detection of Pan-Avian Influenza Virus and H5, H7, H9 subtypes of Avian Influenza Virus using CRISPR/Cas13a and lateral flow assay. Poultry Science February 2025.  Abstract  
submitted by kickingbird at Jan, 1, 2025 from Poultry Science February 2025 (via https://www.sciencedirect.com/science/article/pii/S003257912)
Avian Influenza Virus (AIV) has been prevalent worldwide in recent years, resulting in substantial economic losses in the poultry industry. More importantly, AIV is capable of cross-species transmission ...

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