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2026-6-13 12:41:29
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Di Genova C, Warren CJ, Johnson S, Riccio S, Roper. Pigeons exhibit low susceptibility and poor transmission capacity for H5N1 clade 2.3.4.4b high pathogenicity avian influenza virus. J Gen Virol. 2025 Sep;106(9).  Abstract  
submitted by kickingbird at Sep, 18, 2025 from J Gen Virol. 2025 Sep;106(9) (via https://www.microbiologyresearch.org/content/journal/jgv/10.)
The ongoing panzootic of H5N1 high pathogenicity avian influenza virus (HPAIV) has caused the deaths of over half a billion wild birds and poultry and has led to spillover events in both wild and domestic ...

Sun X, Subbiah J, Belser JA, Brock N, Gansebom S,. Effect of Seasonal Influenza Vaccines on Avian Influenza A(H5N1) Clade 2.3.4.4b Virus Infection in Ferrets. Emerg Infect Dis. 2025 Oct.  Abstract  
submitted by kickingbird at Sep, 18, 2025 from Emerg Infect Dis. 2025 Oct (via https://wwwnc.cdc.gov/eid/article/31/10/25-0668_article)
Highly pathogenic avian influenza A(H5N1) clade 2.3.4.4b viruses have infected >1,000 herds of dairy cattle and hundreds of poultry flocks in the United States since the beginning of 2024. Seventy human ...

Daniels BL, Osnas EE, Boldenow ML, Gerlach RF, Ahl. Observational, Virologic, and Serologic Data Provide Insights into an Outbreak of Highly Pathogenic Avian Influenza among Wild Birds on the Yukon-Kuskokwim Delta, Alaska, USA, in 2022. J Wildl Dis. 2025 Sep 15.  Abstract  
submitted by kickingbird at Sep, 16, 2025 from J Wildl Dis. 2025 Sep 15 (via https://meridian.allenpress.com/jwd/article/doi/10.7589/JWD-)
In 2021-22, clade 2.3.4.4b highly pathogenic avian influenza (HPAI) viruses were introduced by wild birds into North America, leading to geographically widespread disease. In response to HPAI outbreaks ...

Aparicio Coll A, Algarrada Vico L, Rigalós Cases A. Invasive bacterial infection in febrile neonates with influenza infection. An Pediatr (Engl Ed). 2025 Sep 12:503966.  Abstract  
submitted by kickingbird at Sep, 16, 2025 from An Pediatr (Engl Ed). 2025 Sep 12:503966 (via https://www.sciencedirect.com/science/article/pii/S234128792)
Introduction: Febrile infants with a confirmed viral infection are at lower risk of an invasive bacterial infection (IBI). Several authors recommend individualizing screening in febrile infants aged 1 ...

Banyard AC, Coombes H, Terrey J, McGinn N, Seeking. Detection of clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus in a sheep in Great Britain, 2025. Emerg Microbes Infect. 2025 Dec;14(1):2547730.  Abstract  
submitted by kickingbird at Sep, 16, 2025 from Emerg Microbes Infect. 2025 Dec;14(1):2547730 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus (HPAIV) continues to pose a significant global threat, affecting wild and domestic avian, and mammalian species. In early 2024, H5N1 HPAIV was ...

Eid S, Hagag NM, Mosaad Z, Bakry NR, Elhusseiny MH. Genomic surveillance and evolution of co-circulating avian influenza H5N1 and H5N8 viruses in Egypt, 2022-2024. Emerg Microbes Infect. 2025 Sep 15:2562046.  Abstract  
submitted by kickingbird at Sep, 16, 2025 from Emerg Microbes Infect. 2025 Sep 15:2562046 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
For over two decades, avian influenza virus (AIV) has significantly impacted the Egyptian poultry population, with multiple subtypes and genotypes contributing to significant economic and agricultural ...

Chika Kikuchi, etc.,al. [preprint]H3N2 influenza virus tropism shifts to glycan receptors on tracheal ciliated cells. https://doi.org/10.1101/2025.09.12.675939.  Abstract  
submitted by kickingbird at Sep, 16, 2025 from https://doi.org/10.1101/2025.09.12.675939 (via https://www.biorxiv.org/content/10.1101/2025.09.12.675939v1)
Human H3N2 influenza viruses, introduced during the 1968 pandemic, have evolved to recognize human-type sialic acid-containing receptors (Neu5Acα2-6Gal) extended with at least three LacNAc (Galβ1-4GlcNAc) ...

Lucas Stolle, etc.,al. [preprint]Divergent antibody-mediated population immunity to H5, H7 and H9 subtype potential pandemic influenza viruses. https://doi.org/10.1101/2025.09.08.25335309.  Abstract  
submitted by kickingbird at Sep, 16, 2025 from https://doi.org/10.1101/2025.09.08.25335309 (via https://www.medrxiv.org/content/10.1101/2025.09.08.25335309v)
Influenza continues to cause significant mortality globally and possesses substantial pandemic potential. Assessing pandemic risk requires a clear understanding of existing population immunity. Leveraging ...

Chi Chen, Akhila Naru, Vineetha Reddy Mareddy, Sar. [preprint]Highly pathogenic avian influenza A H5N1 virus infection in an immunocompromised domestic cat. DOI:10.1128/asmcr.00134-25.  Abstract  
submitted by kickingbird at Sep, 14, 2025 from DOI:10.1128/asmcr.00134-25 (via https://www.researchgate.net/publication/395450263_Highly_pa)
Background Highly pathogenic avian influenza (HPAI) H5N1 viruses of clade 2.3.4.4b have recently caused widespread outbreaks in mammals, including domestic cats that live closely with humans and other ...

Martha P. Montgomery, etc.,al. Influenza surveillance and vaccine policy in Thailand - a historical perspective. The Lancet Regional Health - Southeast Asia.  Abstract  
submitted by kickingbird at Sep, 14, 2025 from The Lancet Regional Health - Southeast Asia (via https://www.sciencedirect.com/science/article/pii/S277236822)
Prior to 2000, influenza burden in Thailand and other low- and middle-income countries was underappreciated, and influenza vaccination was uncommon. For the last two decades, Thailand Ministry of Public ...

A. Rico, B. Nicks, A. Lago, N. Silva-del-Rio. Insights into Cow-Level Risk Factors for HPAI H5N1 clinical disease in Lactating Holsteins from a Single Outbreak in Colorado (US). An observational study. JDS Communications.  Abstract  
submitted by kickingbird at Sep, 14, 2025 from JDS Communications (via https://www.sciencedirect.com/science/article/pii/S266691022)
Highly Pathogenic Avian Influenza (HPAI) H5N1 (clade 2.3.4.4b) has spilled over into dairy cattle populations in the US. A year after the initial outbreak, many uncertainties remain about the virus's epidemiology. ...

Yang S-T, Hu M-H, Fang W-X, Diao H-M, Musonye HA,. H1N1pdm09 returns: a comparative study in Anhui, China. Microbiol Spectr. 2025 Sep 8:e0221824.  Abstract  
submitted by kickingbird at Sep, 13, 2025 from Microbiol Spectr. 2025 Sep 8:e0221824 (via https://journals.asm.org/doi/10.1128/spectrum.02218-24)
The 2022/2023 season witnessed a rapid resurgence of H1N1pdm09 in Anhui Province, China, surpassing previous years, prompting an examination of hemagglutinin (HA) gene mutations and cross-immunity in this ...

Rimi NA, Fahad MH, Clark A, Sultana R, Hossain K,. Developing a method to estimate aerosol generation during poultry slaughtering and defeathering in Bangladesh: An experimental study. Build Environ . 2025 Mar:271:10.1016/j.buildenv.20.  Abstract  
submitted by kickingbird at Sep, 13, 2025 from Build Environ . 2025 Mar:271:10.1016/j.buildenv.20 (via https://www.sciencedirect.com/science/article/abs/pii/S03601)
Influenza viruses can be aerosolized when slaughtering infected chickens, which increases the risk of zoonotic transmission. We conducted pilot experiments to measure the concentrations of airborne particles ...

Kawano K, Hoshino T, Yano Y, Matsuzaki K. Steady dimer formation by the S31N mutant of influenza A virus M2 protein in living cell membranes. Biochim Biophys Acta Biomembr. 2025 Sep 9:184456.  Abstract  
submitted by kickingbird at Sep, 13, 2025 from Biochim Biophys Acta Biomembr. 2025 Sep 9:184456 (via https://www.sciencedirect.com/science/article/abs/pii/S00052)
The integral matrix protein M2 of the influenza A virus (H3N2) has been proposed to form a proton-selective channel, and is a target of the antiviral drug amantadine hydrochloride (Am). A significant increase ...

Maya Sangesland et al. Functional, immunogenetic, and structural convergence in influenza immunity between humans and macaques. Sci. Transl. Med.17,eady3570(2025).  Abstract  
submitted by kickingbird at Sep, 13, 2025 from Sci. Transl. Med.17,eady3570(2025) (via https://www.science.org/doi/10.1126/scitranslmed.ady3570)
Human B cell immunity to the influenza hemagglutinin (HA) stem, a universal vaccine target, is often stereotyped and immunogenetically restricted, posing hurdles to study outside of humans. Here, we show ...

Ruifeng Xu, Minhao Gao, Nailou Zhang, Zhenhua Wei,. [preprint]Transcontinental Spread of HPAI H5N1 from South America to Antarctica via Avian Vectors. https://doi.org/10.1101/2025.09.06.674605.  Abstract  
submitted by kickingbird at Sep, 12, 2025 from https://doi.org/10.1101/2025.09.06.674605 (via https://www.biorxiv.org/content/10.1101/2025.09.06.674605v1)
Our study has for the first time identified H5N1 strains (clade 2.3.4.4b, genotype B3.2) in brown skuas from the Fildes Peninsula, South Shetland Islands, Antarctica. These findings indicate that highly ...

Antje Steinfurth, etc.,al. [preprint]Investigating high pathogenicity avian influenza virus incursions to remote islands: Detection of H5N1 on Gough Island in the South Atlantic Ocean. https://doi.org/10.1101/2025.09.06.674618.  Abstract  
submitted by kickingbird at Sep, 12, 2025 from https://doi.org/10.1101/2025.09.06.674618 (via https://www.biorxiv.org/content/10.1101/2025.09.06.674618v1)
Understanding the mechanisms underlying the emergence and spread of high pathogenicity avian influenza virus (HPAIV) is critical for tracking its global dissemination, particularly via migratory seabirds, ...

Lan R, Yang J, Li J, Li H, Cao X, Tao M, Chang H,. Continuous evolution of Eurasian avian-like H1N1 swine influenza viruses with pdm/09-derived internal genes enhances pathogenicity in mice. J Virol. 2025 Sep 8:e0043025.  Abstract  
submitted by kickingbird at Sep, 11, 2025 from J Virol. 2025 Sep 8:e0043025 (via https://journals.asm.org/doi/10.1128/jvi.00430-25)
Swine influenza A virus (swIAV) is an important zoonotic pathogen with the potential to cause human influenza pandemics. Swine are considered "mixing vessels" for generating novel reassortant influenza ...

Holly A. Coombes, etc.,al. [preprint]Infection of ratites with clade 2.3.4.4b HPAIV H5N1: Potential implications for zoonotic risk. https://doi.org/10.1101/2025.09.08.674895.  Abstract  
submitted by kickingbird at Sep, 11, 2025 from https://doi.org/10.1101/2025.09.08.674895 (via https://www.biorxiv.org/content/10.1101/2025.09.08.674895v1)
We detected H5N1 high pathogenicity avian influenza in captive Greater Rhea (Rhea americana). Viral genetic analysis revealed the mammalian associated PB2-E627K mutation, indicating selection of mammalian-relevant ...

Zhu, Y., Sun, Y., Deng, X., Cao, P., Li, S., Yu, H. Matrix Protein 1 (M1) of Influenza A Virus: Structural and Functional Insights. Emerging Microbes & Infections.  Abstract  
submitted by kickingbird at Sep, 10, 2025 from Emerging Microbes & Infections (via https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2)
Enveloped viruses rely on matrix proteins for structural integrity and lifecycle progression. Matrix protein 1 (M1) is the most abundant structural protein of influenza A virus (IAV), playing a multifaceted ...

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