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2026-3-7 17:48:05
Article

Jiang M, Zou J, Jin Y, Jiang C, Tu S, Chen T, Guo. Adducin-1 Facilitates Influenza Virus Endosomal Trafficking and Uncoating by Regulating Branched Actin Dynamics and Myosin IIB Activity. Adv Sci (Weinh). 2025 Jun 5:e2417318.  Abstract  
submitted by kickingbird at Jun, 12, 2025 from Adv Sci (Weinh). 2025 Jun 5:e2417318 (via https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.20)
Actin- and microtubule-based transport systems are essential for the trafficking of endocytic viruses and cargoes. Microtubules facilitate long-distance transport; however, the precise role of actin dynamics ...

Sullivan OM, Nesbitt DJ, Schaack GA, Feltman EM, N. IFIT3 RNA-binding activity promotes influenza A virus infection and translation efficiency. J Virol. 2025 Jun 11:e0028625.  Abstract  
submitted by kickingbird at Jun, 12, 2025 from J Virol. 2025 Jun 11:e0028625 (via https://journals.asm.org/doi/10.1128/jvi.00286-25)
Host cells produce a vast network of antiviral factors in response to viral infection. The interferon-induced proteins with tetratricopeptide repeats (IFITs) are important effectors of a broad-spectrum ...

Zhou W, Li X, Tian J, Liu S, Peng C, Li J, Hou G,. Development and application of a real-time fluorescent RAA assay for H9 subtype avian influenza viruses. Virus Genes. 2025 Jun 11.  Abstract  
submitted by kickingbird at Jun, 12, 2025 from Virus Genes. 2025 Jun 11 (via https://link.springer.com/article/10.1007/s11262-025-02167-x)
The H9N2 subtype of avian influenza virus (AIV) is a critical pathogen responsible for avian infectious diseases, inducing respiratory symptoms in poultry and exhibiting high susceptibility to coinfections, ...

Maria Alejandra Romero, etc.,al. Impact of the Avian Influenza Outbreak on the Population Dynamics of South American Sea Lions Otaria byronia in Northern Patagonia. Mar Mam Sci e70031.  Abstract  
submitted by kickingbird at Jun, 12, 2025 from Mar Mam Sci e70031 (via https://onlinelibrary.wiley.com/doi/10.1111/mms.70031)
Understanding the population dynamics of marine mammals is essential for assessing their resilience to historical harvesting pressures and current anthropogenic threats. The South American sea lion (SASL, ...

Yang, B., Gostic, K.M., Adam, D.C. et al. Breadth of influenza A antibody cross-reactivity varies by virus isolation interval and subtype. Nat Microbiol (2025).  Abstract  
submitted by kickingbird at Jun, 11, 2025 from Nat Microbiol (2025) (via https://link.springer.com/article/10.1038/s41564-025-02033-4)
Influenza virus infections generate antibodies that cross-react with antigenically similar viruses. However, the breadth of cross-reactivity is unclear. Here we analysed 200,000 haemagglutination inhibition ...

Yanyupei Yang, etc.,al. [preprint]A prospective, comparative cohort analysis of influenza antibody waning in Michigan and Hong Kong during periods of low influenza circulation. https://doi.org/10.1101/2025.05.26.25328346.  Abstract  
submitted by kickingbird at Jun, 10, 2025 from https://doi.org/10.1101/2025.05.26.25328346 (via https://www.medrxiv.org/content/10.1101/2025.05.26.25328346v)
Background: Reduced influenza transmission during the COVID-19 pandemic prompted concern about waning of population immunity that could lead to subsequent surges in circulation. We evaluated this by comparing ...

Giacinti JA, Rahman I, Wight J, Lewis H, Taylor LU. Comparison of whole blood on filter strips with serum for avian influenza virus antibody detection in wild birds. Conserv Physiol. 2025 Jun 9;13(1):coaf033.  Abstract  
submitted by kickingbird at Jun, 10, 2025 from Conserv Physiol. 2025 Jun 9;13(1):coaf033 (via https://academic.oup.com/conphys/article/13/1/coaf033/815857)
Serological surveillance enhances our understanding of influenza A virus (IAV) exposure and dynamics in wild bird populations. Traditional serum-based testing, while effective, poses logistical challenges ...

Mojsiejczuk L, Whitlock F, Chen H, Magill C, Arand. Multiple introductions of equine influenza virus into the United Kingdom resulted in widespread outbreaks and lineage replacement. PLoS Pathog. 2025 Jun 9;21(6):e1013227.  Abstract  
submitted by kickingbird at Jun, 10, 2025 from PLoS Pathog. 2025 Jun 9;21(6):e1013227 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Influenza A viruses (IAVs) are prime examples of emerging viruses in humans and animals. IAV circulation in domestic animals poses a pandemic risk as it provides new opportunities for zoonotic infections. ...

Oade MS, Te Velthuis AJW. Molecular Insights into Noncanonical Influenza Virus Replication and Transcription. Annu Rev Virol. 2025 Jun 9.  Abstract  
submitted by kickingbird at Jun, 10, 2025 from Annu Rev Virol. 2025 Jun 9 (via https://www.annualreviews.org/content/journals/10.1146/annur)
Influenza A viruses (IAVs) typically cause a mild to moderate respiratory disease, whereas infections with pandemic and highly pathogenic avian IAV strains are frequently associated with high morbidity ...

Martinez-Gzegozewska Y, Rasmussen L, Nebane NM, Mc. High-throughput screening for identification of Influenza A inhibitors using a cell-based immunofluorescence assay. Antiviral Res. 2025 Jun 6:106209.  Abstract  
submitted by kickingbird at Jun, 9, 2025 from Antiviral Res. 2025 Jun 6:106209 (via https://www.sciencedirect.com/science/article/abs/pii/S01663)
A highly sensitive cell-based imaging assay has been used to screen a 200,000 compounds library for potential influenza antivirals. Compounds were screened at a concentration of 10 μM against the influenza ...

Song M, Liang J, Wang S, Gao R, Lu X, Yang W, Chen. E627V mutation in PB2 protein promotes the mammalian adaptation of novel H10N3 avian influenza virus. Vet Res. 2025 Jun 8;56(1):111.  Abstract  
submitted by kickingbird at Jun, 9, 2025 from Vet Res. 2025 Jun 8;56(1):111 (via https://veterinaryresearch.biomedcentral.com/articles/10.118)
Since 2021, the novel H10N3 has caused four cases of human infection in China, the most recent of which occurred in December 2024, posing a potential threat to public health. Our previous studies indicated ...

WPRO. Avian Influenza Weekly Update # 1000: 6 June 2025. WHO.  Abstract  
submitted by kickingbird at Jun, 9, 2025 from WHO (via https://cdn.who.int/media/docs/default-source/wpro---documen)
Avian influenza subtype A(HxNy) normally spreads in birds but can also infect humans. Human infections are primarily acquired through direct contact with infected poultry or contaminated environments. ...

Gao, J., Landgraf, G., Yuan, Y. et al. Influenza neuraminidase active site proximity assay for rapid profiling of inhibitory antibodies and antigenic drift. npj Vaccines 10, 118 (2025).  Abstract  
submitted by kickingbird at Jun, 8, 2025 from npj Vaccines 10, 118 (2025) (via https://www.nature.com/articles/s41541-025-01173-2)
Efficient approaches that can help to select vaccine strains for the influenza virus neuraminidase (NA) antigen are currently needed to advance the development of vaccines containing NA. Here, we present ...

Amalie B. Rasmussen, etc.,al. [preprint]Influenza A virus polymerase co-opts distinct sets of host proteins for RNA transcription or replication. https://doi.org/10.1101/2025.06.06.658254.  Abstract  
submitted by kickingbird at Jun, 8, 2025 from https://doi.org/10.1101/2025.06.06.658254 (via https://www.biorxiv.org/content/10.1101/2025.06.06.658254v1)
The influenza A virus polymerase, consisting of a heterotrimer of three viral proteins, carries out both transcription and replication of the viral RNA genome. These distinct activities are regulated by ...

Sayan Das, etc.,al. [preprint]Enhancing protective efficacy and immunogenicity of hemagglutinin-based influenza vaccine utilizing adjuvants developed by BECC. https://doi.org/10.1101/2025.06.03.657703.  Abstract  
submitted by kickingbird at Jun, 8, 2025 from https://doi.org/10.1101/2025.06.03.657703 (via https://www.biorxiv.org/content/10.1101/2025.06.03.657703v1)
Seasonal influenza viruses continue to pose a significant threat, causing substantial morbidity and mortality in the US and worldwide despite the availability of vaccines and antivirals. These challenges ...

Ou J, Dai Y, Jiang Y, Dai L, Xu L, Lu G, Lou G, Li. Identification of the functional domains of canine tetherin in antiviral activity against canine influenza virus. Front Vet Sci. 2025 May 21;12:1560273.  Abstract  
submitted by kickingbird at Jun, 6, 2025 from Front Vet Sci. 2025 May 21;12:1560273 (via https://www.frontiersin.org/journals/veterinary-science/arti)
Canine influenza virus (CIV) is a respiratory pathogen that causes fever, coughing, and sneezing in dogs and is continuously circulating in canine populations. Tetherin is an antiviral host restriction ...

Kaitlyn Sarlo Davila, etc.,al. [preprint]Susceptibility of calves fed unpasteurized milk from cows experimentally infected with highly pathogenic avian influenza H5N1. https://doi.org/10.21203/rs.3.rs-6681893/v1.  Abstract  
submitted by kickingbird at Jun, 6, 2025 from https://doi.org/10.21203/rs.3.rs-6681893/v1 (via https://www.researchsquare.com/article/rs-6681893/v1)
Highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b genotype B3.13 was confirmed in a dairy cow in Texas on March 25, 2024, by the US Department of Agriculture (USDA) National Veterinary Services ...

van der Vries Erhard, Germeraad Evelien A, Kronema. Swine influenza virus surveillance programme pilot to assess the risk for animal and public health, the Netherlands, 2022 to 2023. Euro Surveill. 2025;30(22):pii=2400664.  Abstract  
submitted by kickingbird at Jun, 6, 2025 from Euro Surveill. 2025;30(22):pii=2400664 (via https://www.eurosurveillance.org/content/10.2807/1560-7917.E)
Swine influenza A viruses (swIAV) are enzootic in pigs in Europe and cause respiratory disease in pigs. Clinical signs include fever, coughing, nasal discharge, sneezing, laboured breathing and loss of ...

Madison T. Gouthro, Emalie K. Hayes, Taylor Prest,. [preprint]Detection of Avian Influenza Virus in Surface Waters Using Passive Samplers. https://doi.org/10.21203/rs.3.rs-6768892/v1.  Abstract  
submitted by kickingbird at Jun, 6, 2025 from https://doi.org/10.21203/rs.3.rs-6768892/v1 (via https://www.researchsquare.com/article/rs-6768892/v1)
Avian influenza (AIV) remains a global concern not only for humans as a pandemic threat but pose a risk to poultry, wildlife, and livestock. The presence of AIV in the environment traditionally has relied ...

Kim, DH., Lee, DY., Seo, Y. et al. Immediate PB2-E627K amino acid substitution after single infection of highly pathogenic avian influenza H5N1 clade 2.3.4.4b in mice. Virol J 22, 183 (2025).  Abstract  
submitted by kickingbird at Jun, 5, 2025 from Virol J 22, 183 (2025) (via https://link.springer.com/article/10.1186/s12985-025-02811-w)
The highly pathogenic avian influenza virus (HPAIV) H5N1 clade 2.3.4.4b has rapidly disseminated globally, with mammalian infections reported in multiple species. Recent evidence of mammal-to-mammal transmission ...

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